Introduction About PANDERM ++ CREAM

PANDERM ++ CREAM is a combination of Clobetasol, Miconazole, and Neomycin, which belong to the group of medicines called Corticosteroids, Antifungals, and Antibiotics. It is used to manage resistant dermatoses (skin infections) with secondary bacterial or fungal infections.

PANDERM ++ CREAM is not recommended for use in patients with rosacea, acne vulgaris, perioral dermatitis, perianal and genital pruritus, viral infections (ex. herpes simplex, chickenpox), or perforated eardrums. Contact your doctor before applying. PANDERM ++ CREAM should be used with caution in patients with liver or kidney disease. Contact your doctor before applying.

PANDERM ++ CREAM is generally not recommended for use in pregnancy unless considered clearly necessary. PANDERM ++ CREAM should be used with caution in breastfeeding women, as it is not known whether it may pass through the breast milk. Contact your doctor before applying. PANDERM ++ CREAM is not recommended for use in children under 2 years of age. Contact your doctor before applying.

Dosage adjustment is not required for PANDERM ++ CREAM in the geriatric population. However, the greater sensitivity of some older individuals cannot be ruled out. Contact your doctor before applying. The most common side effects of this medicine are skin rashes, itching, redness, burning sensations, and contact dermatitis. Contact your physician if any of the symptoms worsen.

Uses Of PANDERM ++ CREAM

• Used to manage resistant dermatoses (skin infections) with secondary bacterial or fungal infections

How PANDERM ++ CREAM Works

PANDERM ++ CREAM helps to manage infection, where Clobetasol has anti-inflammatory, antipruritic, and vasoconstrictive properties that block the production of certain chemical messengers (prostaglandins) that make the skin red, swollen, and itchy. Miconazole belongs to the antifungal category, which stops the growth of fungi, while Neomycin belongs to the antibiotic category, which stops the growth of bacteria in the skin.

How to use PANDERM ++ CREAM

Apply PANDERM ++ CREAM as directed by your physician. It is for external use only. Wash your hands with soap and water, apply a thin layer of the medicine to the affected area of the skin, and rub it gently. Avoid contact with the eyes, face, groin, or skin folds.

Side Effects Of PANDERM ++ CREAM

How To Manage Side Effects

Skin rash Or Itching

Avoid hot showers because hot water can irritate the skin. Do not scratch the affected area. Use sunscreen and protective clothing when outdoors. Regularly use unscented moisturizers to soothe and hydrate the affected area. Contact your doctor if itching worsens.

Warning & Precautions

Pregnancy

Monitoring required

PANDERM ++ CREAM is not recommended for use in pregnancy unless considered clearly necessary. Contact your doctor before applying.

Breastfeeding

Consult your doctor

PANDERM ++ CREAM should be used with caution in breastfeeding women, as it is not known whether it may pass through the breast milk. Contact your doctor before applying.

Kidney

Use with Caution

PANDERM ++ CREAM should be used with caution in patients with kidney disease. Contact your doctor before applying.

Liver

Use with Caution

PANDERM ++ CREAM should be used with caution in patients with liver disease. Contact your doctor before applying.

Allergy

Contraindicated

Do not use PANDERM ++ CREAM if you are allergic to Clobetasol, Miconazole, Neomycin, or any other ingredients of this medicine.

Use In Pediatrics

Contraindicated

PANDERM ++ CREAM is not recommended for use in children under 2 years of age. Contact your doctor before applying.

Use In Geriatrics

Consult your doctor

Dosage adjustment is not required for PANDERM ++ CREAM in the geriatric population. However, the greater sensitivity of some older individuals cannot be ruled out. Contact your doctor before applying.

Interactions

A. Drug-Drug interactions:

Before applying PANDERM ++ CREAM tell your doctor if you are taking,

• Ritonavir (medicines used for HIV infections)
• Itraconazole (a medicine used for fungal infections)
• Amikacin, gentamicin (medicines used for bacterial infections)
• Neuromuscular-blocking agents like atracurium and pancuronium (medicines used in anesthesia)
• Warfarin (medicines used to manage blood clots)

Overdosage:

If you or anyone else accidentally uses too much of PANDERM ++ CREAM, consult your doctor immediately or visit the nearby hospital.

Synopsis

More Information

• Keep out of reach of children
• Store PANDERM ++ CREAM below 25°C

FAQs About PANDERM ++ CREAM

Q: What are the possible side effects of applying PANDERM ++ CREAM?

A: The most common side effects of PANDERM ++ CREAM are skin rash, itching, redness, burning sensation, and contact dermatitis. Contact your physician if any of the symptoms worsen.

Q: Can I use PANDERM ++ CREAM with children?

A: PANDERM ++ CREAM is not recommended for use in children under 2 years of age. Contact your doctor before applying.

Q: For what conditions is PANDERM ++ CREAM used?

A: PANDERM ++ CREAM is used to manage resistant dermatoses (skin infections) with secondary bacterial or fungal infection.

Q: Does PANDERM ++ CREAM cause itching on the skin?

A: Yes, PANDERM ++ CREAM may cause skin itching at the site of application as a temporary side effect. However, if the itching persists or worsens, consult your doctor for advice.

Q: Can I stop using PANDERM ++ CREAM when my symptoms are relieved?

A: No, do not stop using PANDERM ++ CREAM and complete the full course of management, even if you feel better. Your symptoms may improve before the infection is completely managed.

Q: Who should not use PANDERM ++ CREAM?

A: PANDERM ++ CREAM is not recommended for use in patients with rosacea, acne vulgaris, perioral dermatitis, perianal and genital pruritus, viral infections (ex. herpes simplex, chickenpox), perforated eardrums, or in children. Contact your doctor before applying.

Q: How does PANDERM ++ CREAM work?

A: PANDERM ++ CREAM helps to manage infection, where Clobetasol has anti-inflammatory, antipruritic, and vasoconstrictive properties, which block the production of certain chemical messengers (prostaglandins) that make the skin red, swollen, and itchy. Miconazole belongs to the antifungal category, which stops the growth of fungi, while Neomycin belongs to the antibiotic category, which stops the growth of bacteria in the skin.

Q: How do I use PANDERM ++ CREAM?

A: Apply PANDERM ++ CREAM as directed by your physician. It is for external use only. Wash your hands with soap and water, apply a thin layer of the medicine to the affected area of the skin, and rub it gently. Avoid contact with the eyes, face, groin, or skin folds.

Q: Can I use other medicines with PANDERM ++ CREAM?

A: Before using PANDERM ++ CREAM, inform your doctor if you are using, have used, or might use any other medicine, including prescription, non-prescription, or any herbal medicine, as these might interact with each other and cause serious side effects.

Q: Is PANDERM ++ CREAM safe during pregnancy?

A: PANDERM ++ CREAM is not recommended for use in pregnancy unless considered clearly necessary. Contact your doctor before applying.

Q: What happens if I accidentally use more PANDERM ++ CREAM?

A: If you or anyone else accidentally uses too much of PANDERM ++ CREAM, contact your doctor immediately or go to a hospital right away.

Q: What precautions must be taken while using PANDERM ++ CREAM?

A: Before using PANDERM ++ CREAM, inform your doctor if you have liver or kidney disease as a precaution.

References

1. K.D. Tripathi. Drugs acting on the skin and mucous membrane, Antifungal Drugs & Aminoglycoside Antibiotics. Essentials of medical pharmacology. Seventh edition. 2013. Page – 895, 792, 750.

2. Bethesda (MD). Clobetasol. National Institute of Health. NLM. National Centre for Biotechnology Information. PubChem Compound Summary. 2004. [Accessed on 26th March 2024] https://pubchem.ncbi.nlm.nih.gov/compound/5311051

3. Bethesda (MD). Miconazole. National Institute of Health. NLM. National Centre for Biotechnology Information. PubChem Compound Summary. 2004. [Accessed on 26th March 2024] https://pubchem.ncbi.nlm.nih.gov/compound/4189

4. Bethesda (MD). Neomycin. National Institute of Health. NLM. National Centre for Biotechnology Information. PubChem Compound Summary. 2004. [Accessed on 26th March 2024] https://pubchem.ncbi.nlm.nih.gov/compound/Neomycin

5. Blue Cross labs. Clobetasol, Miconazole and Neomycin. [Revised on May 2020] [Accessed on 26th March 2024] https://www.bluecrosslabs.com/img/sections/SONADERM-NM-CREAM.pdf

Useful Diagnostic Tests

• Complete Blood Count (CBC)/ Hemogram
• Thyroid Stimulating Hormone (TSH)
• Free Thyroxine (Ft4)
• Free Triiodothyronine (Ft3)
• Urine Routine & Microscopy
• Skin Care Package
• Random Blood Sugar (Rbs)
• Healthy Midlife Checkup
• Men Health Checkup - Advanced
• Complete Women Checkup
• Senior Citizen Checkup - Female
• Senior Citizen Checkup – Male
• Women Health Checkup – Essential
• Full Body Checkup - Gold
• Elderly Checkup - Female
• Elderly Checkup - Male
• Full Body Checkup - Silver

Author Details

Written By Dr. N. Sai Swaroop - Pharm.D

Reviewed By Dr. Sankara Babu Gorle - MBBS, MD(Pharmacology) View profile

Last updated on 10 Apr 2024 | 04:52 PM(IST)