Introduction About LIMOSONE NM CREAM

LIMOSONE NM CREAM is a combination of Clobetasol, Miconazole and Neomycin which belongs to the group of medicines called Corticosteroids, Antifungals and Antibiotics. It is used to manage resistant dermatoses (skin infections) with secondary bacterial or fungal infection.

LIMOSONE NM CREAM is not recommended for use in patients with rosacea, acne vulgaris, perioral dermatitis, perianal and genital pruritus, viral infections (ex. herpes simplex, chickenpox) and perforated eardrum. Contact your doctor before applying. LIMOSONE NM CREAM should be used with caution in patients with liver or kidney disease. Contact your doctor before applying.

LIMOSONE NM CREAM is generally not recommended for use in pregnancy unless considered clearly necessary. LIMOSONE NM CREAM should be used with caution in breastfeeding women as it is not known whether it may pass through the breast milk. Contact your doctor before applying. LIMOSONE NM CREAM is not recommended for use in children under 2 years of age. Contact your doctor before applying.

Dosage adjustment is not required for LIMOSONE NM CREAM in the geriatric population. However, greater sensitivity of some older individuals cannot be ruled out. Contact your doctor before applying. The most common side effects of this medicine are skin rash, itching, redness, burning sensation and contact dermatitis. Contact your physician if any of the symptoms worsen.

Uses Of LIMOSONE NM CREAM

• Used to manage resistant dermatoses (skin infections) with secondary bacterial or fungal infection

How LIMOSONE NM CREAM Works

LIMOSONE NM CREAM helps to manage infection, where Clobetasol have anti-inflammatory, antipruritic, and vasoconstrictive properties, which blocks the production of certain chemical messengers (prostaglandins) that make the skin red, swollen, and itchy. Miconazole belongs to antifungal which stops the growth of fungi while Neomycin belongs to antibiotic which stops the growth of bacteria in the skin.

How to use LIMOSONE NM CREAM

Apply LIMOSONE NM CREAM as directed by your physician. It is for external use only. Wash your hands with soap and water and apply a thin layer of the medicine to the affected area of the skin and rub it gently. Avoid contact with eyes, face, groin or in the skin folds.

Side Effects Of LIMOSONE NM CREAM

How To Manage Side Effects

Skin rash Or Itching

Avoid hot showers because hot water can irritate the skin. Do not scratch the affected area. Use sunscreen and protective clothing when outdoors. Regularly use unscented moisturizers to soothe and hydrate the affected area. Contact your doctor if itching worsens.

Warning & Precautions

Pregnancy

Monitoring required

LIMOSONE NM CREAM is not recommended for use in pregnancy unless considered clearly necessary. Contact your doctor before applying.

Breastfeeding

Use with Caution

LIMOSONE NM CREAM should be used with caution in breastfeeding women as it is not known whether it may pass through the breast milk. Contact your doctor before applying.

Kidney

Use with Caution

LIMOSONE NM CREAM should be used with caution in patients with kidney disease. Contact your doctor before applying.

Liver

Use with Caution

LIMOSONE NM CREAM should be used with caution in patients with liver disease. Contact your doctor before applying.

Allergy

Contraindicated

Do not use LIMOSONE NM CREAM if you are allergic to Clobetasol, Miconazole, Neomycin, or to any other ingredients of this medicine.

Use In Pediatrics

Contraindicated

LIMOSONE NM CREAM is not recommended for use in children under 2 years of age. Contact your doctor before applying.

Use In Geriatrics

Use with Caution

Dosage adjustment is not required for LIMOSONE NM CREAM in the geriatric population. However, greater sensitivity of some older individuals cannot be ruled out. Contact your doctor before applying.

Interactions

A. Drug-Drug interactions:

Before applying LIMOSONE NM CREAM tell your doctor if you are taking,

• ritonavir (medicines used for HIV infections)
• itraconazole (medicines used for fungal infections)
• amikacin, gentamicin (medicines used for bacterial infections)
• neuromuscular blocking agents like atracurium, pancuronium (medicines used in anaesthesia)
• warfarin (medicines used to manage or manage blood clots)

Overdosage:

If you or anyone else accidentally uses too much of LIMOSONE NM CREAM, consult your doctor immediately or visit the nearby hospital.

Synopsis

More Information

• Keep out of reach of children
• Store LIMOSONE NM CREAM below 25°C

FAQs About LIMOSONE NM CREAM

Q: What are the possible side effects of applying LIMOSONE NM CREAM?

A: The most common side effects of this medicine are skin rash, urticaria, itching, redness, burning sensation and contact dermatitis. Contact your physician if any of the symptoms worsen.

Q: Can I use LIMOSONE NM CREAM in children?

A: LIMOSONE NM CREAM is not recommended for use in children under 2 years of age. Contact your doctor before applying.

Q: For what conditions LIMOSONE NM CREAM is used?

A: LIMOSONE NM CREAM is used to manage resistant dermatoses (skin infections) with secondary bacterial or fungal infection.

Q: Does LIMOSONE NM CREAM cause itching on the skin?

A: Yes, LIMOSONE NM CREAM may cause skin itching at the site of application as a temporary side effect. However, if the itching persists or worsens, consult your doctor for advice.

Q: Can I stop using LIMOSONE NM CREAM when my symptoms are relieved?

A: No, do not stop using LIMOSONE NM CREAM and complete the full course of management, even if you feel better. Your symptoms may improve before the infection is completely managed.

Q: Who should not use LIMOSONE NM CREAM?

A: LIMOSONE NM CREAM is not recommended for use in patients with rosacea, acne vulgaris, perioral dermatitis, perianal and genital pruritus, viral infections (ex. herpes simplex, chickenpox), perforated eardrum. Contact your doctor before applying.

References

1. K.D. Tripathi. Drugs acting on the skin and mucous membrane, Antifungal Drugs & Aminoglycoside Antibiotics. Essentials of medical pharmacology. Seventh edition. 2013. Page – 895, 792, 750.

2. Bethesda (MD). Clobetasol. National Institute of Health. NLM. National Centre for Biotechnology Information. PubChem Compound Summary. 2004. [Accessed on 17th June 2022] https://pubchem.ncbi.nlm.nih.gov/compound/5311051

3. Bethesda (MD). Miconazole. National Institute of Health. NLM. National Centre for Biotechnology Information. PubChem Compound Summary. 2004. [Accessed on 17th June 2022] https://pubchem.ncbi.nlm.nih.gov/compound/4189

4. Bethesda (MD). Neomycin. National Institute of Health. NLM. National Centre for Biotechnology Information. PubChem Compound Summary. 2004. [Accessed on 17th June 2022] https://pubchem.ncbi.nlm.nih.gov/compound/Neomycin

5. Blue Cross labs. Clobetasol, Miconazole and Neomycin. [Revised on May 2020] [Accessed on 24th June 2022] https://www.bluecrosslabs.com/img/sections/SONADERM-NM-CREAM.pdf