Introduction About GANATON OD 150MG CAPSULE

GANATON OD 150MG CAPSULE contains Itopride which belongs to a group of medicine called Gastroprokinetic agents. It is used in the management of gastrointestinal symptoms of functional dyspepsia (indigestion) and non-ulcer dyspepsia (bloating, upper abdominal pain, anorexia, heartburn, nausea and vomiting). GANATON OD 150MG CAPSULE is not recommended for use in patients with an increase in gastrointestinal motility (gastrointestinal bleeding, mechanical obstruction or perforation).

The safety and effectiveness of GANATON OD 150MG CAPSULE in pregnant women and children under 16 years of age has not yet been established. It is not recommended for use in breastfeeding women. GANATON OD 150MG CAPSULE should be used with caution in elderly patients. The most common side effects of taking GANATON OD 150MG CAPSULE are diarrhoea, constipation, headache, abdominal pain, dizziness or feeling irritated. Consult your doctor if symptoms do not improve.

Uses Of GANATON OD 150MG CAPSULE

• Manage gastrointestinal symptoms of functional and non-ulcer indigestion (chronic gastritis)

How GANATON OD 150MG CAPSULE Works

GANATON OD 150MG CAPSULE stops the activity of dopamine D2 receptor and increases acetylcholine (messenger in the nervous system) concentrations which accelerates gastric emptying, improves gastric movement and reduces nausea and vomiting.

How to use GANATON OD 150MG CAPSULE

Always take GANATON OD 150MG CAPSULE exactly as prescribed by your doctor. Swallow the medicine with a glass of water. Do not crush or chew the medicine. Your doctor will decide the right dose and duration for you depending on your age, body weight and disease condition.

Side Effects Of GANATON OD 150MG CAPSULE

How To Manage Side Effects

Constipation: 

Take fiber-rich foods such as fresh fruit, vegetables and cereals, and drink plenty of water. Exercise more regularly. Consult your doctor if symptoms do not improve.

Headache:

Rest and drink plenty of fluids. Apply a cold, wet cloth, or ice pack to your forehead. Rest in a quiet, comfortable, dark room. Consult your doctor if symptoms do not improve.

Diarrhoea:

Drink a lot of fluids, such as water or squash, to avoid dehydration. Do not take any other medicines without speaking to a doctor. Consult your doctor if symptoms do not improve.

Stomach pain:

Try to rest and relax. You can eat and drink slowly or small have frequent meals. Keeping a heating pad on your stomach may also help. If the pain persists, speak to your doctor.

Warning & Precautions

Pregnancy

GANATON OD 150MG CAPSULE is not recommended for use in pregnant women unless the benefits outweigh the potential risks. Consult your doctor before taking it.

Breastfeeding

GANATON OD 150MG CAPSULE is not recommended for use in breastfeeding women as it is excreted in the breast milk. Your doctor will decide whether to discontinue nursing or to discontinue the drug, considering the importance of the drug to the mother.

Allergy

Do not take GANATON OD 150MG CAPSULE if you are allergic (hypersensitive) to this medicine or any other ingredients in this medicine.

Interactions

A. Drug-Drug Interaction:

Before taking GANATON OD 150MG CAPSULE inform your doctor if you are taking any of the following medicines:

• anti-ulcer drugs (Ex. cimetidine, ranitidine, teprenone and cetraxate) to manage gastric ulcers
• anticholinergic drugs (Ex. dicyclomine) to manage irritable bowel syndrome

Overdosage:

If you or anyone else accidentally use too much of GANATON OD 150MG CAPSULE, consult your doctor immediately or visit the nearby hospital.

Synopsis

More Information

• Store at room temperature 15-30°C
• Keep out of reach of children

FAQs About GANATON OD 150MG CAPSULE

What is GANATON OD 150MG CAPSULE used for?

GANATON OD 150MG CAPSULE is used in the management of gastrointestinal symptoms of functional dyspepsia (indigestion), non-ulcer dyspepsia (bloating, upper abdominal pain, anorexia, heartburn, nausea and vomiting).

How does GANATON OD 150MG CAPSULE work?

GANATON OD 150MG CAPSULE stops the activity of dopamine D2 receptor and increases acetylcholine (messenger in the nervous system) concentrations which accelerates gastric emptying, improves gastric movement and reduces nausea and vomiting.

Does GANATON OD 150MG CAPSULE cause diarrhoea?

Yes, GANATON OD 150MG CAPSULE may cause diarrhoea as a common side effect. Drink a lot of fluids, such as water or squash, to avoid dehydration. Do not take any other medicines without speaking to a doctor. Consult your doctor if symptoms do not improve.

Can GANATON OD 150MG CAPSULE be used in breastfeeding women?

GANATON OD 150MG CAPSULE is not recommended for use in breastfeeding women as it is excreted in the breast milk. Your doctor will decide whether to discontinue nursing or to discontinue the drug, considering the importance of the drug to the mother.

Can GANATON OD 150MG CAPSULE be used along with dicyclomine?

Do not take anticholinergic drugs (Ex. dicyclomine) along with this medicine as it can affect the way this medicine acts on your body. Consult your doctor before taking any other medicines.

References

1. KD. Tripathi. Essentials of medical pharmacology. Seventh edition. 2013. Chapter – 47, Antiemetic, Prokinetic and Digestant Drugs. 2013. Page – 663, 667.

2. Xuan Huang, Bin Lv, Shuo Zhang, Yi-Hong Fan, and Li-Na Meng. Itopride therapy for functional dyspepsia: A meta-analysis. National Library of Medicine, National Institute of Health. Pubmed Central. December 2012 [Accessed on 6th October 2022] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3544044/

3. Eman Mohamed Elmokadem , Radwa Maher El Borolossy , Ahmed M Bassiouny , Maha Gamil Hanna , Ebtissam Abdel Ghaffar Darweesh , Nagwa A Sabri. The efficacy and safety of itopride in feeding intolerance of critically ill patients receiving enteral nutrition: a randomized, double-blind study. National Library of Medicine, National Institute of Health. Pubmed.gov. March 2021. [Accessed on 6th October 2022] https://pubmed.ncbi.nlm.nih.gov/33740892/

4. Abbott laboratories limited. Itopride Hydrochloride. [Revised on September 2007] [Accessed on 6th October 2022] https://www.medicine.abbott/content/dam/bss/divisionalsites/epd/pk/Product%20Information/Leaflet%20Ganaton%2050.pdf