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Introduction About RYTSTAT 50 TABLET
RYTSTAT 50 TABLET contains Desidustat which belongs to the group of medicines called anti-anemics. It is used in the management of anemia associated with chronic kidney disease. It works by stimulating your body release a hormone called erythropoietin which regulates the synthesis of red blood cell (RBC) count in the body.
Studies have shown that desidustat is also helpful in restoring RBC count in patients suffering from COVID-2019 infections and chemotherapy induced anaemia.
RYTSTAT 50 TABLET should be used under proper medical supervision. Do not take RYTSTAT 50 TABLET if you are allergic to Desidustat or to any ingredients of this medicine. Consult your doctor before taking RYTSTAT 50 TABLET if you are pregnant or breastfeeding. Inform your doctor about all your pre-existing disease conditions as a precaution before taking this medicine.
During management with RYTSTAT 50 TABLET, your doctor recommends several blood tests and regularly monitor the levels of electrolytes such as potassium, hemoglobin, and blood cells in your blood to analyze the improvements in your health condition.
The most common side effects of taking RYTSTAT 50 TABLET are abdominal pain, vomiting, headache, fever, weakness, and peripheral edema. Consult your doctor if these side effect does not resolve on its own.
Uses Of RYTSTAT 50 TABLET
- It is used in the management of anaemia associated with chronic kidney disease
How RYTSTAT 50 TABLET Works
Desidustat is a hypoxia-inducible factor-prolyl hydroxylase (HIF-PH) inhibitor. It works by blocking the actions of an enzyme called prolyl hydroxylase which is responsible for destruction of red blood cells. As a results, it stimulates erythropoietin production and regulates erythropoiesis.
How to use RYTSTAT 50 TABLET
Take RYTSTAT 50 TABLET as advised by your physician. Swallow the medicine with a glass of water. Do not crush or chew the medicine. Do not exceed the recommended daily dosages.
Your doctor will decide the correct dose and duration depending on your age, body weight, and disease condition.
Side Effects Of RYTSTAT 50 TABLET
Common
- Abdominal pain
- Vomiting
- Headache
- Fever
- Weakness
- Peripheral edema (swelling of hands and legs)
Stop taking RYTSTAT 50 TABLET and inform your doctor if you experience any of the following side effects:
- Severe allergic reactions with shortness of breath
How To Manage Side Effects
Headache
Managing a headache involves several strategies to alleviate discomfort. Start by ensuring you are well-hydrated, as dehydration can contribute to headaches. Rest in a quiet, dark room to minimize sensory stimuli, and try using a cold or warm compress on your forehead or neck. Over-the-counter pain relievers like acetaminophen or ibuprofen can be effective, but it's essential to follow recommended dosages and consult a healthcare professional if you have any concerns or underlying health conditions. Practice relaxation techniques, such as deep breathing or meditation, to reduce stress and tension. If your headache persists or becomes severe, seeking medical advice is advisable for a proper diagnosis and tailored management plan.
Nausea And Vomiting
Managing vomiting involves several steps to help alleviate discomfort and promote recovery. Stay hydrated by sipping clear fluids like water, electrolyte drinks, or ginger tea in small amounts throughout the day. Avoiding solid foods temporarily and opting for bland, easily digestible options such as crackers or plain rice can be beneficial. Resting in a comfortable position and avoiding strenuous activities can also aid in recovery. If vomiting persists or is accompanied by other concerning symptoms, seeking medical attention is crucial for proper evaluation and> management. Over-the-counter antiemetic medications may be considered under medical guidance, but it's essential to consult a healthcare professional before taking any medication, especially for prolonged or severe cases of vomiting.
Warning & Precautions
Pregnancy
Consult your doctorThere is no proper information available regarding the use of RYTSTAT 50 TABLET among pregnant women. Therefore, consult your doctor before taking it.
Breastfeeding
Consult your doctorThere is no proper information available regarding the use of RYTSTAT 50 TABLET among breastfeeding women. Therefore, consult your doctor before taking it.
Driving and Using Machines
Use with CautionDo not drive or operate any machinery if your ability is affected by RYTSTAT 50 TABLET.
Alcohol
Consult your doctorIt is not known whether consumption of alcohol is considered safe while taking RYTSTAT 50 TABLET. Please consult your doctor before taking it.
Liver
Use with CautionRYTSTAT 50 TABLET should be used with caution in patients with liver problems. Therefore, consult your doctor before taking it.
Allergy
ContraindicatedDo not take RYTSTAT 50 TABLET if you are allergic to Desidustat or to any other ingredients of this medicine.
Use In Pediatrics
Consult your doctorThere is no information regarding the use of RYTSTAT 50 TABLET among children and adolescents (aged below 18 years). Therefore, consult your doctor before administration.
Use In Geriatrics
Use with CautionRYTSTAT 50 TABLET should be used with caution among elderly patients. Therefore, consult your doctor before taking it.
Interactions
A. Drug-Drug interactions
Before taking RYTSTAT 50 TABLET, inform your doctor if you are taking any of the following medicines including, prescription, non-prescription and over the counter medicines.
Overdosage:
If you or anyone else accidentally took more RYTSTAT 50 TABLET, consult your doctor immediately or visit the nearby hospital.
Synopsis
| Drug | : | Desidustat |
| Pharmacological Category | : | HIF-PH inhibitor |
| Therapeutic Indication | : | Anemia caused due to chronic kidney disease |
| Dosage Forms | : | Tablet |
More Information
- Keep RYTSTAT 50 TABLET out of reach of children
- Store below 30°C
FAQs About RYTSTAT 50 TABLET
Q: What is RYTSTAT 50 TABLET and what is it used for?
A: RYTSTAT 50 TABLET is an oral medicine given for the management of anaemia associated with chronic kidney disease among patients undergoing dialysis or not. It is a prescription medicine approved in India and can be taken only under the advice and guidance of a doctor.
Q: What is chronic kidney disease or CKD?
A: Chronic kidney disease or CKD is a condition in which the kidneys are damaged and lose their ability to filter blood. Consequently, the accumulation of excess waste and toxins in the body can give rise to various health issues. Factors contributing to the risk of kidney disease include elevated blood pressure, diabetes, heart disease, and a familial predisposition to kidney failure.
Q: What test can help me know if I have any kidney disease?
A: Your doctor may advise you to take a blood test to find out if you have kidney disease. The test measures the amount of waste product called creatinine in your blood. The doctor will use the blood test results, your age, gender, weight, and ethnic group to calculate how many milliliters of waste your kidneys should be able to filter in a minute. This calculation is known as your estimated glomerular filtration rate or eGFR. Healthy kidneys should be able to filter more than 90 mL/min. You may have kidney disease if your rate is lower than this.
Q: How to manage chronic kidney disease?
A: You are at risk for kidney disease if you have high blood pressure, diabetes, heart disease, or a family history of kidney failure. If you have risk factors, it is advisable to get tested for kidney disease and protect your kidneys by changing your diet, lifestyle and controlling your blood pressure and blood glucose levels.
Q: How is anemia related to chronic kidney disease?
A: Your kidneys make an important hormone called erythropoietin (EPO) that tells your body to make red blood cells. When you have kidney disease, kidneys fail to make enough EPO. Low EPO levels cause a drop in your red blood cell count leading to anemia.
Q: Who is more likely to have anemia in CKD?
A: The likelihood of developing anemia escalates as kidney disease progresses. Individuals with Chronic Kidney Disease (CKD) and diabetes face a heightened risk of anemia, experiencing its onset earlier and often exhibiting more severe manifestations compared to those with CKD without diabetes. Additionally, individuals aged 60 years and above are more prone to developing anemia in conjunction with CKD.
Q: What are the symptoms of anemia in patients with CKD?
A: Some of the symptoms of anemia with CKD include fatigue, dizziness, pale skin, headache, body-ache, shortness of breath, and fast or irregular heartbeats.
Q: What are the complications of anemia in patients with CKD?
A: In people with CKD, severe anemia can increase the risk of developing heart problems and strokes because of low oxygen levels in the body, which results from the decreasing level of red blood cells in the body.
Q: How to take RYTSTAT 50 TABLET?
A: RYTSTAT 50 TABLET should be used under proper medical supervision. Swallow the medicine with a glass of water. Do not crush or chew the medicine. Do not exceed the recommended daily dosages.
Q: How long should I take RYTSTAT 50 TABLET?
A: You need to take RYTSTAT 50 TABLET as long as your doctor prescribes you the medicine. Your doctor will decide the correct dose and duration of therapy for you depending upon your age, body weight and disease condition.
Q: What to do if I forgot to take a dose of RYTSTAT 50 TABLET?
A: If you forgot to take a dose of RYTSTAT 50 TABLET, take it as soon as you remember. However, if it is time for the next dose of RYTSTAT 50 TABLET, skip the missed dose and take the next one regularly. Do not take a double dose of RYTSTAT 50 TABLET to compensate for the missed ones.
Q: What are the most common side effects of taking RYTSTAT 50 TABLET?
A: The most common side effects of taking RYTSTAT 50 TABLET are abdominal pain, vomiting, headache, fever, weakness, and peripheral edema. Consult your doctor if these side effect does not resolve on its own.
Q: Can I stop taking RYTSTAT 50 TABLET without consulting your doctor?
A: No. You should not stop taking RYTSTAT 50 TABLET without consulting your doctor because it may lead to reversal of symptoms. If you feel better after using RYTSTAT 50 TABLET, consult your doctor for advice.
Q: Will taking a higher dose of RYTSTAT 50 TABLET be more effective?
A: No, taking a higher dose of RYTSTAT 50 TABLET will not be effective rather it can lead to toxicity. Always take the dose prescribed by your doctor. If the prescribed dose is not effective for you, consult your doctor for advice. Your doctor might increase the dose or suggest an alternative therapy.
Q: Can RYTSTAT 50 TABLET be used during pregnancy?
A: There is no proper information available regarding the use of RYTSTAT 50 TABLET among pregnant women. Therefore, consult your doctor before taking it.
References
1. Desidustat: First Approval. Sohita Dhillon. National Library of Medicine. National Center for Biotechnology Information. PMC. PubMed Central. July 2022. [Accessed on 24th January 2024] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9281218/
Useful Diagnostic Tests
- Hemoglobin (Hb)
- Kidney Function Test (KFT)
- Healthy Midlife Checkup
Author Details
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