Introduction About REZULUNG D TABLET

REZULUNG D TABLET contains Acebrophylline, desloratadine and montelukast that help in improving breathing difficulties associated with various conditions like asthma, hay fever and allergic rhinitis. These conditions trigger an allergic reaction like narrowing of the airway passages like bronchi which in turn leads to difficulty in breathing and chest pain.

REZULUNG D TABLET relaxes the airways, thereby removing the obstruction in the respiratory system and facilitating easy breathing. It also relieves various skin reactions such as itch and rash.

REZULUNG D TABLET is not recommended in patients suffering from various kidney disorders, liver disorders, and heart disorders like an irregular heartbeat (arrhythmia) and chest pain due to an insufficient supply of blood to the heart muscles (myocardial infarction).

REZULUNG D TABLET is not recommended for use by children below the age of 15 years. It is recommended to consult a doctor before taking it, as only he can decide the required dosage of REZULUNG D TABLET based on body mass, age, and the condition of the infection. The most common side effects reported with the use of REZULUNG D TABLET are diarrhoea, nausea, and vomiting. Consult your doctor if any of your symptoms get worse.

Uses Of REZULUNG D TABLET

• Manage breathlessness and wheezing caused due to an obstruction in the lungs (chronic obstructive pulmonary disease)
• Manage breathlessness and chest pain occurring due to the narrowing of the tubes called bronchi (bronchial asthma)
• Manage inflammation of bronchi (bronchitis)
• Manage the inflammation of the nasal passages characterized by sneezing, runny or itchy nose, itchy palate and eyes, in adults and adolescents of 12 years of age and older due to allergy (Allergic Rhinitis) ( Ex. Hay fever or allergy to dust mites)
• Relieve the dry, itchy skin associated with Hives/ Urticaria
• Prevent exercise-related breathlessness due to the narrowing of airways

How REZULUNG D TABLET Works

REZULUNG D TABLET contains acebrophylline, desloratadine, and montelukast. Acebrophylline is a bronchodilator that helps in relaxing the muscles of the bronchi, thus widening the lumen (bronchodilator) and regulating mucous production and clearance, thus resulting in relief from inflammation (anti-inflammatory property), which provides relief from breathing difficulties.

Desloratadine is a tricyclic antihistamine that helps to control various allergic reactions and also does not make you feel sleepy or drowsy. Montelukast blocks the action of various allergy-producing chemicals in the body (leukotrienes), which provides relief and improves the symptoms of asthma and/or hay fever and/or seasonal allergies like wheezing and breathing difficulty by managing the narrowing and swelling of lung airways.

Thus, together, these medicines present in REZULUNG D TABLET help in improving breathing difficulties associated with various causes.

How to use REZULUNG D TABLET

Take REZULUNG D TABLET as advised by your physician. Swallow the medicine with a glass of water. Do not crush or chew the medicine. It is recommended to take medicine thirty to sixty minutes before or after food. Your doctor will determine the correct dose and duration for you depending on your age, body weight, and disease condition.

Side Effects Of REZULUNG D TABLET

How To Manage Side Effects

Constipation

Eat healthy meals that are rich in fiber. Try to incorporate leafy green vegetables and whole grains into your diet. Take an adequate amount of water. Consult your doctor if it persists for a long time or worsens with time.

Diarrhea

Stick to simple meals. Consume less rich or spicy foods. To compensate for the loss of water and minerals, consume an oral rehydration solution. Stay hydrated. Consult your doctor if it persists for a long time or worsens with time.

Headache

Stay hydrated and get as much rest as you can. Stay away from harsh lights and loud sounds. Apply a pain-relieving balm to your forehead and/or take aspirin or acetaminophen. If the headache persists or worsens, consult your doctor.

Nausea And Vomiting

Stick to simple meals. Consume less rich or spicy foods. Stay hydrated. Consult your doctor if it persists for a long time or worsens with time.

Tiredness

Drink plenty of fluids and electrolytes and eat a balanced diet with an increased frequency of meals. Try to do regular, minimal exercise and follow a proper sleep schedule. If the symptom does not improve, consult your doctor about it.

 

Warning & Precautions

Pregnancy

Contraindicated

REZULUNG D TABLET is not recommended for use in pregnant women or those who are planning pregnancy. Consult your doctor before taking REZULUNG D TABLET.

Breastfeeding

Contraindicated

REZULUNG D TABLET is not recommended for use in nursing women due to a lack of safety data. Consult your doctor before taking REZULUNG D TABLET.

Driving and Using Machines

Use with Caution

REZULUNG D TABLET does not affect your ability to drive or use machinery.

Alcohol

Contraindicated

REZULUNG D TABLET is not recommended to be taken along with alcohol as it may lead to an increase in the severity of side effects like fainting and dizziness.

Kidney

Contraindicated

REZULUNG D TABLET is not recommended for patients suffering from any disorder of kidney. Consult your doctor before taking REZULUNG D TABLET.

Liver

Contraindicated

REZULUNG D TABLET is not recommended for patients suffering from any disorder of the liver. Consult your doctor before taking REZULUNG D TABLET.

Allergy

Contraindicated

Do not take REZULUNG D TABLET if you are allergic to acebrophylline and/or theophylline and/or any other xanthine derivative and/or desloratadine and/or montelukast and/or any other constituent of REZULUNG D TABLET.

 

Lungs

Use with Caution

REZULUNG D TABLET is to be used with caution in patients suffering from asthma. Consult your doctor before taking REZULUNG D TABLET.

Heart Disease

Contraindicated

REZULUNG D TABLET is not recommended in patients suffering from pain in the chest due to insufficient oxygen supply to muscles of the heart (Acute Myocardial Infarction) and/or irregular heartbeat (arrhythmia) and/or low blood pressure. Consult your doctor before taking REZULUNG D TABLET.

Use In Pediatrics

Contraindicated

REZULUNG D TABLET is not recommended to be taken by children less than the age of 15 years. Consult your doctor before using REZULUNG D TABLET.

Interactions

A. Drug-Drug Interactions:

Before taking REZULUNG D TABLET, inform your doctor if you are taking any of the following medicine:

• medicines to manage gout (ex. allopurinol)
• medicines to manage ulcers (ex. cimetidine)
• medicines to relieve inflammatory disorders (corticosteroids)
• medicines to manage infections (ex, ciprofloxacin, erythromycin, amoxicillin, doxycycline)
• medications to manage parasitic (pinworm) infection (ex. thiabendazole)
• medicines to manage heart disorders (ex. diltiazem, verapamil, isoprenaline, frusemide)
• oral medicines for contraception (ex. estrogen)
• medicines to manage epilepsy (ex. phenobarbital, phenytoin)
• medicines used to manage various infections like tuberculosis (ex. rifampicin)
• medicines used to manage increased bad lipids in plasma (ex. gemfibrozil)

Overdosage:

If you or anyone else accidentally take too much of REZULUNG D TABLET, consult your doctor immediately or visit the nearby hospital. Symptoms of overdose are
nausea, severe vomiting, pain in the stomach and blood in vomiting (haematemesis). If abdominal pain persists for a long time, it may indicate inflammation of the pancreas (Pancreatitis). Other symptoms include restlessness, increased tonicity of muscles (hypertonia), exaggerated limb reflexes and convulsions. Increased tendency to sleep and increased thirst can also be experienced on overdosage with REZULUNG D TABLET.

Synopsis

More Information

• Keep REZULUNG D TABLET out of reach from children
• Keep REZULUNG D TABLET safe from light and humidity
• Store at below 25° Celsius

FAQs About REZULUNG D TABLET

Q: What is REZULUNG D TABLET used for?

A: REZULUNG D TABLET is used to provide relief from the symptoms associated with various conditions like asthma, hay fever, and allergic rhinitis. These conditions trigger allergic reactions like narrowing of the airway passages like the bronchi, which in turn lead to difficulty breathing and chest pain. REZULUNG D TABLET relaxes the airways, thereby removing the obstruction in the respiratory system and facilitating easy breathing.

Q: Can I drive after taking REZULUNG D TABLET?

A: Yes, you can drive after taking REZULUNG D TABLET as it does not affect your ability to drive or use machinery. However, it is advised that you consult your doctor first.

Q: Can I take REZULUNG D TABLET during pregnancy?

A: Pregnant women or women planning to become pregnant should avoid using REZULUNG D TABLET. Make sure to consult your doctor before taking REZULUNG D TABLET.

Q: How do I take REZULUNG D TABLET?

A: Take REZULUNG D TABLET as advised by your physician. Take REZULUNG D TABLET as advised by your physician. Swallow the medicine with a glass of water. Do not crush or chew the medicine. It is recommended to take medicine thirty to sixty minutes before or after food. Your doctor will determine the correct dose and duration for you depending upon your age, body weight, and disease condition.

Q: Can REZULUNG D TABLET be taken by children?

A: REZULUNG D TABLET is not recommended to be taken by children younger than 15 years old. Consult your doctor before using REZULUNG D TABLET. It is recommended to consult a doctor before taking it, as only he can decide the required dosage of REZULUNG D TABLET based on body mass, age, and the condition of the infection.

Q: How should I store REZULUNG D TABLET?

A: REZULUNG D TABLET should be stored away from light and at a temperature below 250 °C. Also, REZULUNG D TABLET must be kept out of the reach of children.

Q: Can I take alcohol after taking REZULUNG D TABLET?

A: No, it is recommended to avoid drinking alcohol while taking and/or after taking REZULUNG D TABLET because it might make you dizzy.

References

1. KD Tripathi Drugs for Cough and Bronchial Asthma  Essentials of medical pharmacology. Seventh edition Page- 218.

2. KD Tripathi. Histamine and Antihistaminics. Essentials of medical pharmacology. Seventh edition Page 159.

3. Ciebiada, M., Górska-Ciebiada, M., DuBuske, L.M. and Górski, P., 2006. Montelukast with desloratadine or levocetirizine for the treatment of persistent allergic rhinitis. Annals of allergy, asthma & immunology. [Revised in November 2006] [Accessed on 8th August 2022] https://pubmed.ncbi.nlm.nih.gov/17165277/

4. Nettis, E., Colanardi, M.C., Paradiso, M.T. and Ferrannini, A., 2004. Desloratadine in combination with montelukast in the treatment of chronic urticaria: a randomized, double-blind, placebo-controlled study. Clinical & Experimental Allergy. [Revised in 2004] [Accessed on 8th August 2022] https://citeseerx.ist.psu.edu/viewdoc/download?doi=10.1.1.616.47&rep=rep1&type=pdf

5. Agliati, G., 1995. Acebrophylline in the treatment of chronic obstructive pulmonary disease. Current therapeutic research. [Revised in February 1995] [Accessed on 8th August 2022] https://www.sciencedirect.com/science/article/abs/pii/0011393X95850422

6. Ciplamed Acebrophyllin. [Last Reviewed in November 2013] [Accessed on 8th August 2022] https://www.ciplamed.com/content/mucophylin-capsules#:~:text=In%20healthy%20volunteers%2C%20given%20200,acetic%20acid%20after%201%20hour

7. Accord Healthcare Limited. Electronic Medicines Compendium (EMC). [Revised in April 2022] [Accessed on 8th August 2022] https://www.medicines.org.uk/emc/files/pil.12005.pdf

8. Accord Healthcare Limited. Electronic Medicines Compendium (EMC). [Revised in September 2020] [Accessed on 8th August 2022] https://www.medicines.org.uk/emc/files/pil.1243.pdf

9. Steris Healthcare. [Published on 28th April 2021] [Accessed on 8th August 2022] https://www.sterisindia.com/latest-update/-montelukast-acebr/4977

10. Divine Saviour. [Accessed on 8th August 2022] https://divinesavior.in/products-list.php?cat=20&ptype=Respiratory#prettyPhoto   

Useful Diagnostic Tests

• Liver Function Test
• Kidney Function Test
• Complete Blood Count