Introduction About RENX SACHET

Avoid taking RENX SACHET with orange juice or other fruit juices that are known to raise the blood potassium levels. It is not recommended for use if you are allergic to calcium polystyrene sulfonate and in patients with other conditions such as bowel obstruction or blocked intestine, thyroid problems and high blood calcium levels. RENX SACHET should be used with caution if you have breathing or chest problems, kidney or heart problems.

RENX SACHET should be used with caution during pregnancy and breastfeeding. It should be used with caution in children and adolescents (below 18 years of age). Consult your doctor before taking. The common side effects associated with the use of RENX SACHET are tiredness, confusion, muscle weakness, muscle cramps, altered heart rate, nausea and vomiting. Contact your doctor if any of the side effects worsens.

• hyperkalemia due to acute and chronic renal failure
• hyperkalemia (associated with anuria, severe oliguria and in patients requiring dialysis)

Before taking RENX SACHET, inform your doctor, if you are taking any of the following medicines:

• medicines used to manage heart problems (ex. Digitalis)
• medicines used for acid reflux or constipation such as non-absorbable cation-donating antacids and laxatives (ex. magnesium hydroxide, aluminium carbonate)
• medicines used to manage heart burn or peptic ulcer (ex. aluminium hydroxide)
• medicines used to manage underactive thyroid (ex. levothyroxine, thyroxine)
• medicines used to manage depression (ex. Lithium)
• calcium (used as a calcium supplement in diet)

B. Drug-Food Interactions:

Avoid taking RENX SACHET with orange juice or other fruit juices that are known to raise the blood potassium levels.

Overdosage:

If you or anyone else accidentally takes too much of RENX SACHET, consult your doctor immediately or visit the nearby hospital. Overdosage symptoms of RENX SACHET are irritability, confusion, muscle weakness, diminished reflexes, paralysis, inability to concentrate, delayed thought process, breathing problems, fast/pounding heartbeat, muscle cramps, sleep apnea (serious sleep disorder) and irregular heartbeat.

A: It is used to manage increased potassium levels in blood (hyperkalemia) due to acute and chronic renal failure that occurs after certain conditions. RENX SACHET is also used in patients with hyperkalemia associated with anuria, severe oliguria (condition marked by low urine output) and in patients requiring dialysis.

Q: What happens if you take more RENX SACHET than your required dose?

A: If you or anyone else accidentally takes too much of RENX SACHET, consult your doctor immediately or visit the nearby hospital. Overdosage symptoms of RENX SACHET are irritability, confusion, muscle weakness, diminished reflexes, paralysis, inability to concentrate, breathing problems, pounding heartbeat, or muscle cramps.

Q: Who should avoid taking RENX SACHET?

A: RENX SACHET is not recommended for use if you are allergic to calcium polystyrene sulfonate and in patients with other conditions such as bowel obstruction or blocked intestine, thyroid problems or high levels of calcium in your blood such as excessive thirst, frequent urination.

Q: How does RENX SACHET work?

A: RENX SACHET works by releasing calcium ions in the stomach which binds to hydrogen ions and it gets exchanged with free potassium ions in the large intestine, that gets eliminated with the faeces along with the excess potassium ions thereby resulting in reduced potassium levels in the body.

Q: How to take RENX SACHET?

A: Take RENX SACHET as advised by your physician. Avoid using orange juice or other fruit juices. Your doctor will decide the correct dose of RENX SACHET and duration for you depending upon your age, body weight and disease condition.

Q: When to stop taking RENX SACHET?

A: Stop taking RENX SACHET and contact your doctor if you experience any of the serious side effects such as severe stomach or rectal pain, bloating, severe constipation, severe nausea and vomiting, abnormal stools (black, bloody, or tarry), coughing with blood, or vomit resembling coffee grounds.

2. Nobuhiro Takeuchi, Yusuke Nomura, Testuo Meda, Masato Iida, Akihito Ohtsuka, Kazuyoshi Naba. Development of Colonic Perforation during Calcium Polystyrene Sulfonate Administration: A Case Report. NIH National Library of Medicine. National Centre for Biotechnology Information. PMC PubMed Central. December 2013. [Accessed on 23rd July 2022] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3872384/

3. Jing Wang, Meng-Meng Lv, Odeh Zach, Ling-Yu Wang, Meng-Ying Zhou, Gui-Rong Song, Xu Zhang, Hong-Li Lin. Calcium-Polystyrene Sulfonate Decreases Inter-Dialytic Hyperkalemia in Patients Undergoing Maintenance Hemodialysis: A Prospective, Randomized, Crossover Study. NIH National Library of Medicine, National center for biotechnology information. Pubmed.gov. December 2018. [Accessed on 23rd July 2022] https://pubmed.ncbi.nlm.nih.gov/30109784/

4. Hospimax. Potblok (Calcium Polystyrene Sulphonate 15 gm). [Accessed on 23rd July 2022] http://www.hospimax.com/formulation/PotbloK%20Website%20Content.pdf

5. Sanofi-aventis Canada Inc. Resonium calcium. [Revised in September 2018] [Accessed on 23rd July 2022] https://products.sanofi.ca/en/resonium-calcium.pdf

6. Laboratorios Rubio, S.A. Industria. Electronic Medicines Compendium (EMC). [Revised in October 2021] [Accessed on 23rd July 2022] https://www.medicines.org.uk/emc/files/pil.13346.pdf