Introduction About PH 4 SYRUP

PH 4 SYRUP is a combination of Magaldrate and Simethicone, which belongs to the group of medicines called Antacids and Anti-flatulent agents, respectively. It is used for the management of heartburn (burning sensation in the chest due to stomach acid travelling up towards the throat), hyperacidity (excess acidity in the stomach), indigestion, flatulence (expulsion of gas out of the body's intestines via the anus), bloating (buildup of gas in the stomach and intestines), and sour stomach.

It is also used to manage esophagitis (inflammation of the lining of the esophagus) or gastritis (inflammation of the lining of the stomach), stomach or stress ulcers (open sores that develop on the lining of the stomach, which may also occur due to stress), and gastroesophageal reflux (a condition in which the stomach contents move up into the esophagus (food pipe).

Avoid alcohol and carbonated drinks and reduce intake of citrus fruit juices and caffeine to reduce acidity and gas problems. Also try to maintain a healthy diet plan with adequate sleep to get better results.

PH 4 SYRUP is not recommended for use in patients with high magnesium levels in blood, low phosphate levels in the blood, diarrhea, and severe liver or kidney impairment.

Before taking PH 4 SYRUP, inform your doctor if you have any kidney problems, appendicitis, stomach pain, nausea, vomiting, bowel blockage, rectal bleeding of unknown cause, a magnesium-restricted diet, and if you have a surgical history of bowel surgery.

PH 4 SYRUP should be used in pregnant and breast-feeding women only if advised by the doctor. Consult your child’s doctor for advice before giving PH 4 SYRUP to your child.

The most common side effects of taking PH 4 SYRUP are diarrhea, constipation, and chalky taste. Consult your doctor if any of the side effects worsen or bother you.

Uses Of PH 4 SYRUP

Used to manage the following:

• heartburn, hyperacidity, indigestion
• flatulence
• bloating, sour stomach
• esophagitis/gastritis
• stomach/stress ulcers
• gastroesophageal reflux

How PH 4 SYRUP Works

PH 4 SYRUP contains magaldrate and simethicone, where magaldrate works by neutralizing the pH of gastric acid in the stomach and suppressing the symptoms of acid-reflux-related issues. Simethicone is an anti-flatulent agent that works by breaking up gas bubbles, and it helps the gas to be eliminated easier.

How to use PH 4 SYRUP

Take PH 4 SYRUP as advised by your physician. Shake well before use. Use a measuring cup to properly measure the dose. Do not drink water or any other liquid after taking PH 4 SYRUP, which may decrease its effectiveness. Your doctor will decide the correct dose and duration for you depending upon your age, body weight, and disease condition.

Side Effects Of PH 4 SYRUP

How To Manage Side Effects

Constipation

Take fiber-rich foods in your diet, such as fresh fruits, vegetables, and whole grain cereals, and drink plenty of fluids. Exercise regularly (such as walking) and stay active. Consult your doctor if the constipation does not improve.

Diarrhea

Drink a lot of fluids, such as water or fruit juices, to keep yourself hydrated. Do not take any medicine on your own to manage diarrhea. Consult your doctor if the diarrhea does not improve.

Warning & Precautions

Pregnancy

Monitoring required

PH 4 SYRUP can be used in pregnant women only if considered clearly necessary. Consult your doctor for advice before taking PH 4 SYRUP.

Breastfeeding

Monitoring required

PH 4 SYRUP can be used in breast-feeding women only if advised by the doctor. Consult your doctor before taking PH 4 SYRUP.

Kidney

Consult your doctor

PH 4 SYRUP is not recommended for use in patients with severe kidney impairment. It should be used with caution in patients with kidney problems. Consult your doctor before taking PH 4 SYRUP.

Liver

Contraindicated

PH 4 SYRUP is not recommended for use in patients with severe liver impairment. Consult your doctor before taking PH 4 SYRUP.

Allergy

Contraindicated

Do not take PH 4 SYRUP if you are allergic to magaldrate, simethicone, or any other ingredients of this medicine. Consult your doctor before taking PH 4 SYRUP.

Use In Pediatrics

Consult your doctor

Consult your child’s doctor for advice before giving PH 4 SYRUP to your child.

Interactions

A. Drug-drug interactions:

Before taking PH 4 SYRUP, inform your doctor if you are taking any of the following medicines:

• warfarin (used to manage or manage blood clotting)
• citrate salt (found in calcium supplements (used to manage calcium deficiency) and laxatives such as magnesium citrate (used to manage constipation)
• alendronic acid (used to manage osteoporosis)
• sodium polystyrene sulfonate (used to manage high potassium levels in the blood)
• hormonal medicines for thyroid problems (Ex. levothyroxine)
• fluconazole (used to manage fungal infections)
• penicillamine (used to manage Wilson’s disease (too much copper in the body))
• mycophenolate (used to manage rheumatoid arthritis)
• medicines used to manage bacterial infections (Ex. cefaclor, doxycycline, ciprofloxacin)
• quinidine (used to manage irregular heartbeats)

Overdosage:

If you or anyone else accidentally takes too much of PH 4 SYRUP, consult your doctor immediately or go to a nearby hospital right away.

Synopsis

More Information

FAQs About PH 4 SYRUP

Q: How does PH 4 SYRUP work?

A: PH 4 SYRUP contains magaldrate and simethicone, where magaldrate works by neutralizing the pH of gastric acid in the stomach and suppressing the symptoms of acid reflux-related issues. Simethicone is an anti-flatulent agent that works by breaking up gas bubbles, and it helps the gas to be eliminated easier.

Q: What are the side effects of taking PH 4 SYRUP?

A: The most common side effects of taking PH 4 SYRUP are diarrhea, constipation, and chalky taste. Consult your doctor if any of the side effects worsen or bother you.

Q: Is it safe to take PH 4 SYRUP during pregnancy?

A: PH 4 SYRUP can be used in pregnant women only if advised by the doctor. Consult your doctor for advice before taking PH 4 SYRUP if you are pregnant or planning to get pregnant.

Q: Can PH 4 SYRUP be used in patients with kidney problems?

A: PH 4 SYRUP is not recommended for use in patients with severe kidney impairment. It should be used with caution in patients with kidney problems. Consult your doctor before taking PH 4 SYRUP.

Q: How to take PH 4 SYRUP?

A: Take PH 4 SYRUP as advised by your physician. Shake well before use. It is advised to take PH 4 SYRUP 40 minutes before having food. It is better to take the medicine in the morning for better results. Do not drink water or any other liquid after taking PH 4 SYRUP, which may decrease its effectiveness. Do not take antacid medicines half an hour before or after taking this medicine. Your doctor will decide the correct dose and duration for you depending upon your age, body weight, and disease condition.

Q: What is PH 4 SYRUP used for?

A: PH 4 SYRUP is used for the management of heartburn, hyperacidity, indigestion, flatulence, bloating, and sour stomach. It is also used to manage esophagitis or gastritis, stomach or stress ulcers, and gastroesophageal reflux. Consult your doctor before taking it.

Q: Who should not take PH 4 SYRUP?

A: PH 4 SYRUP is not recommended for use if you have high magnesium levels in the blood, low phosphate levels in the blood, diarrhea, severe kidney impairment, severe liver impairment, or if you are allergic to magaldrate, simethicone. Consult your doctor before taking PH 4 SYRUP.

Q: What precautions must be taken while using PH 4 SYRUP?

A: Before taking PH 4 SYRUP, inform your doctor if you have kidney problems, appendicitis, stomach pain, nausea, vomiting, bowel blockage, rectal bleeding of unknown cause, are following a low magnesium diet, or have had bowel surgery.

Q: Is PH 4 SYRUP safe for kids?

A: Consult your child’s doctor for advice before giving PH 4 SYRUP to your child.

Q: What should I avoid while taking PH 4 SYRUP?

A: Avoid alcohol and carbonated drinks and reduce intake of citrus fruit juices and caffeine to reduce acidity and gas problems. Also try to maintain a healthy diet plan with adequate sleep to get better results.

References

1. Goodman and Gillman’s. Drugs affecting gastrointestinal system. The pharmacological basis of therapeutics. Eleventh Edition. Page-974.

2. Torshin, I. Yu, O. A. Gromova, and N. A. Kuricina. Anta rite-synergistic combination of magaldrate+ simethicone with gastroprotective properties. Pharmacokinetics and Pharmacodynamics. 2018. [Accessed on 9th August 2024] https://www.pharmacokinetica.ru/jour/article/view/73?locale=en_US

3. Ljerka Brecevik, Ingrid Bosan Kilibarda, Franjo Strajnar. Mechanism of antifoaming action of simethicone. Journal of Applied Toxicology (1994). [Accessed on 9th August 2024] https://analyticalsciencejournals.onlinelibrary.wiley.com/doi/abs/10.1002/jat.2550140311

4. Celocid Suspension (Magaldrate and Simethicone). Biobrick Pharma [Accessed on 9th August 2024] https://www.biobrickpharma.com/product/celocid/

5. Magaldrate + Simethicone. MK Medicine. [Accessed on 9th August 2024] https://www.mkmedicine.in/magaldrate-simethicone-sugar-free-digestive-relief-suspension.html

6. Magvon Syrup (Magaldrate + Simethicone). Vontima lifecare. [Accessed on 9th August 2024] https://www.vontimalifecare.com/pharmaceutical-syrup-and-suspension.html

7. Nevigel Suspension (Magaldrate + simethicone). Bionova pharma. [Accessed on 9th August 2024] https://www.bionova.co.in/general-medicines.html

8. Magaldrate + Simethicone Suspension. Alaina pharma. [Accessed on 9th August 2024] http://alainapharma.com/44.html

9. Riegel Suspension. Magaldrate + simethicone. Moderik Healthcare. [Accessed on 9th August 2024] https://www.moderik.in/product/ricgel-susp/

10. Beliwell Suspension. Magaldrate + simethicone. Santo Medi Sciences Pvt. Ltd. [Accessed on 9th August 2024] https://www.santomedisciences.com/product/magaldrate-400-mg-simethicone-60-mg-5-ml-suspensions

11. Medical union pharmaceuticals. Simethicone Emulsion. [Revised in September 2013] [Accessed on 9th August 2024] https://pharmacia1.com/wp-content/uploads/2016/03/SIMETHICONE-EMULSION-PATIENT-INFORMATION-LEAFLET.pdf

Useful Diagnostic Tests

• Complete Blood Count (CBC)/ Hemogram
• Helicobacter Pylori Iga
• Helicobacter Pylori Igg
• Monsoon Gastro Infection Panel
• Gastro / Gut Health Panel
• Liver Function Test (LFT)
• Kidney Function Test (KFT)
• Men Health Checkup – Advanced
• Complete Women Checkup
• Full Body Checkup - Gold