Introduction About PASITREX OINTMENT

PASITREX OINTMENT contains Calcipotriol which belongs to group of medicines called Anti-psoriatics. PASITREX OINTMENT is used to manage plaque psoriasis (long-lasting autoimmune disease that cause thicky scaly patches on skin) in affected individuals.

PASITREX OINTMENT is not recommended for use in patients allergic to Calcipotriol. It is also not recommended for use in patients with a history of hypersensitivity reaction (immune response to an allergen), calcium metabolism disorders (due to high/low calcium levels), vitamin D toxicity, and/or severe liver & kidney disease.

Before applying PASITREX OINTMENT, inform your doctor if you are a smoker, undergoing ultraviolet management, and/or suffering from exfoliative/pustular psoriasis.

[GBNKEYWORLD] should be used with caution during pregnancy only if it is clearly necessary. It is also used with caution in breastfeeding women which is advised not to apply on breast area while feeding the baby.

PASITREX OINTMENT is not recommended for use in children (aged below 6 years) and is advised to be used with caution in elderly patients (aged 65 years/above) after consulting the doctor.  

The most common side effects of applying PASITREX OINTMENT are pain at the site of application, burning/stinging sensation, skin irritation, itching, itchy rash, and skin redness. Consult your doctor if any of these symptoms worsens.

Uses Of PASITREX OINTMENT

• Manage plaque psoriasis in affected individuals

How PASITREX OINTMENT Works

PASITREX OINTMENT works by inhibiting cell growth and its development without causing any harm to the cell which results in decreased growth of abnormal cells thus controlling psoriatic condition and managing the condition in affected individuals.

How to use PASITREX OINTMENT

Always apply PASITREX OINTMENT as directed by your physician. It is for external use only. Apply a thin layer of this medicine on the affected area. Managed areas on the face need not be covered with a plaster or bandage. Do not use this medicine on your face.

Side Effects Of PASITREX OINTMENT

How To Manage Side Effects

Dry Skin:

Try moisturizing your skin with an ointment, cream, or lotion 2 or 3 times a day, or as often as needed.  Moisturizers help to keep the area moisture, so they work best on damp skin. After you bathe, pat your skin dry then apply your moisturizer. Try to avoid using skin care products and soaps that contain alcohol, fragrances, dyes, or other chemicals.

Itchy Skin:

Try to pat or tap your skin instead of scratching it. Hold a damp towel to cool your skin. Wear loose clothing and avoid tight clothes, or clothes made from wool or synthetic fabrics. Avoid using perfumed soaps, deodorants or moisturizers and use a skin softener regularly.

Warning & Precautions

Pregnancy

PASITREX OINTMENT should be used with caution in pregnant women only if it is clearly necessary. Consult your doctor before applying it.

Breastfeeding

PASITREX OINTMENT should be used with caution in breastfeeding women. It is not recommended to be applied on breast area while feeding the baby. Consult your doctor before applying the medicine.

Driving and Using Machines

PASITREX OINTMENT generally does not have any effect on your ability to drive or use machines. Consult your doctor before applying the medicine.

Kidney

PASITREX OINTMENT is not recommended for use in patients suffering from severe kidney problems. Consult your doctor before applying the medicine.

Liver

PASITREX OINTMENT is not recommended for use in patients suffering from severe liver problems. Consult your doctor before applying the medicine.

Allergy

Do not take PASITREX OINTMENT if you are allergic to Calcipotriol or any of the other ingredients of this medicine.

Interactions

A. Drug - Drug interactions:

Inform your doctor about all the medicines you use, including prescription and non-prescription medicines, and herbal supplements.

Over dosage:

If you or anyone else applies too much of PASITREX OINTMENT or accidentally swallows it, consult your doctor immediately or visit the nearby hospital. Symptoms of overdose include elevated serum calcium levels with signs such as increased urinary frequency, excessive thirst, loss of appetite, dry/metallic taste in the mouth, stomach upsets.

Synopsis

More Information

• Keep PASITREX OINTMENT out of reach of children
• Store below 25°C

FAQs About PASITREX OINTMENT

Does PASITREX OINTMENT cause skin irritation?

Yes, PASITREX OINTMENT may cause skin irritation. Avoid harsh soaps and detergents, lotions, perfumed soaps and known allergy triggers that may help to soothe irritated skin. Consult your doctor before using.

Can I take other calcium supplements along with PASITREX OINTMENT?

As calcium supplements might increase calcium level in blood, consult your doctor before applying PASITREX OINTMENT to avoid excess production of calcium in blood which may occur with signs such as increased urinary frequency, excessive thirst, loss of appetite, dry/metallic taste in the mouth, stomach upsets.

How much dose of PASITREX OINTMENT can i use in a day?

Always apply PASITREX OINTMENT as directed by your physician. It is for external use only. Apply a thin layer of this medicine on the affected area. Managed areas on the face need not be covered with a plaster or bandage. Do not use this medicine on your face.

Can a patient undergoing UV light management apply PASITREX OINTMENT?

Yes, PASITREX OINTMENT can be used but with caution in patients undergoing ultraviolet light management since the medicine may get degraded upon exposure to ultraviolet resulting in reduced effect of the drug. Consult your doctor before applying the medicine.

References

1. K.D. Tripathi. Drugs Acting on Skin and Mucous Membranes. Essentials of medical pharmacology. Seventh edition. 2013. Page 891. [Accessed on 5th May 2022].

2. Luigi Naldi, Berthold Rzany. Psoriasis (chronic plaque). NIH National Library of Medicine. National Center for Biotechnology Information. PMC PubMed Central. January 2009. [Accessed on 5th May 2022] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2907770/

3. LEO Laboratories Ltd. U.S. Food and Drugs Administration (USFDA) [Revised in March 2015] [Accessed on 5th May 2022] https://www.accessdata.fda.gov/drugsatfda_docs/label/2015/020273s013,020554s012lbl.pdf

4. Leo Laboratories Limited. Electronic Medicines Compendium (EMC) [Revised in November 2019] [Accessed on 5th May 2022] https://www.medicines.org.uk/emc/files/pil.981.pdf

5. Biocon Biologics India Limited. Calpsor Lotion. [Revised in August 2019] [Accessed on 5th May 2022] https://www.biocon.com/docs/domestic-market-pi/immuno/CALPSOR%20LOTION%20PI.pdf

Useful Diagnostic Tests

• Skin biopsy