Introduction About METROZIDE GEL

METROZIDE GEL contains Metronidazole which belongs to the group of medicines called Antiprotozoal drugs. It helps to control infection and inflammation in certain skin problems, such as rosacea (skin redness and flushing with or without small red pus-filled pustules on the skin) and acne. It is also helpful in the management of wound infections, diabetic foot ulcers and vaginal infections.

METROZIDE GEL is for external use only. Cleanse and dry the affected areas before applying the medicine. Do not expose the managed areas in direct sunlight. Wear protective clothing and consult your doctor for a suitable sunscreen while going outdoors.

Before using METROZIDE GEL, inform your doctor if you are suffering from any kind of blood disorders (Ex. blood dyscrasias) or neurological disorders (such as nerve damage). You must also inform your doctor if you suffer from any allergic skin conditions (such as contact dermatitis) as a precaution.

Do not use METROZIDE GEL without consulting your doctor if you are pregnant or breastfeeding. The most common side effects of using METROZIDE GEL are skin dryness, redness, itching and/or irritation at the site of application. Consult your doctor if any of these side effect bothers you.

Uses Of METROZIDE GEL

It is used to control infections and inflammatory lesions associated with:

• Rosacea (skin redness and flushing with or without small red pus-filled pustules on the skin)
• Acne
• Diabetic foot ulcers
• Wounds that have severe inflammation, redness and odour
• Vaginal infections

How METROZIDE GEL Works

METROZIDE GEL is an antiprotozoal agent with antibacterial properties. It works by killing the susceptible germs that cause infections in the body. When applied on the skin, it destroys the infection causing germs and manages their further growth and multiplication which therefore reduces the severity of the infection.

How to use METROZIDE GEL

Always apply METROZIDE GEL as directed by your physician. It is for external use only. Clean and dry the affected area before application. Apply a thin layer of METROZIDE GEL on the affected areas. Wash your hands before and after application.

Avoid contact of METROZIDE GEL with eyes, ears, mouth, or nose. In case of accidental contact, rinse it with plenty of warm water. Your doctor will decide the correct dose and duration of therapy for you depending upon your skin condition. 

Side Effects Of METROZIDE GEL

How To Manage Side Effects

Skin rash Or Itching

Avoid hot showers because hot water can irritate your skin further. Do not scratch the affected area. Use protective clothing while going outdoors. Consult your doctor for a suitable moisturizer that suits your skin. Consult your doctor if your skin condition worsens.

Warning & Precautions

Pregnancy

Monitoring required

METROZIDE GEL is not recommended for use in pregnant women unless considered necessary by the physician. Therefore, consult your doctor before application.

Breastfeeding

Monitoring required

METROZIDE GEL is not recommended for use in breastfeeding women unless considered necessary by the physician. Therefore, consult your doctor before application.

Alcohol

Consult your doctor

As METROZIDE GEL is applied only on the skin, it is unlikely to react with alcohol. However, avoid consumption of alcohol while you are undergoing therapy with METROZIDE GEL as a precaution.

Allergy

Contraindicated

Do not use METROZIDE GEL if you are allergic to Metronidazole.

Use In Pediatrics

Consult your doctor

The safety and effectiveness of METROZIDE GEL have not been established in children and adolescents (aged below 18 years). Therefore, consult your doctor before application.

Use In Geriatrics

Use with Caution

METROZIDE GEL should be used with caution in elderly patients. Therefore, consult your doctor before application.

Interactions

A. Drug - Drug interactions:

Before applying METROZIDE GEL, inform your doctor if you are taking:

• anti-coagulants (medicines used for thinning the blood) Ex. warfarin

Overdosage:

If you or anyone else used more METROZIDE GEL or swallowed the medicine, contact your doctor immediately or visit the nearby hospital straight away.

Synopsis

More Information

• Keep METROZIDE GEL out of reach of children
• Do not store above 25°C

FAQs About METROZIDE GEL

Q: What is the use of METROZIDE GEL?

A: METROZIDE GEL helps to control infection and inflammation in certain skin problems, such as rosacea and acne. It is also helpful in the management of wound infections, diabetic foot ulcers and vaginal infections.

Q: How METROZIDE GEL works in my body?

A: METROZIDE GEL is an antiprotozoal agent with antibacterial properties. It works by killing the susceptible germs that cause infections in the body. When applied on the skin, it destroys the infection causing germs and manages their further growth and multiplication which therefore reduces the severity of the infection.

Q: How to use METROZIDE GEL?

A: METROZIDE GEL is for external use only. Clean and dry the affected area before application. Apply a thin layer of METROZIDE GEL on the affected areas. Wash your hands before and after application. Avoid contact of METROZIDE GEL with eyes, ears, mouth, or nose.

Q: Can METROZIDE GEL be used in children?

A: The safety and effectiveness of METROZIDE GEL have not been established in children and adolescents (aged below 18 years). Therefore, consult your doctor before application.

Q: Can I stop using METROZIDE GEL once my symptoms subside?

A: Do not stop using METROZIDE GEL once your symptoms subside. It is important to take the full course of METROZIDE GEL to achieve better results. Failing to complete the full course of the therapy or skipping doses in between the therapy may not result in adequate infection control. It may also cause your symptoms to reappear.

Q: What are the common side effects of using METROZIDE GEL?

A: The most common side effects of using METROZIDE GEL are skin dryness, redness, itching and/or irritation at the site of application. Consult your doctor if any of these side effect bothers you.

Q: For how long should I take METROZIDE GEL?

A: Apply METROZIDE GEL for the stipulated duration as prescribed by your doctor. Do not skip the medicine or stop using it on your own to achiever quick results.

Q: Will METROZIDE GEL be more effective if I overuse it?

A: Do not overuse METROZIDE GEL. Excessive application of METROZIDE GEL may cause skin irritation and dryness. Therefore, use METROZIDE GEL only directed by your physician.

Q: Can the use of METROZIDE GEL make my skin sensitive to sunlight?

A: Yes. METROZIDE GEL may make your skin more sensitive to sunlight. Therefore, use protective clothing while going outdoors. Do not exposure the affected part of the skin to the direct sunlight. Consult your doctor if you require any sunscreen to protect your skin while going outdoors. Consult your doctor if your skin condition worsens.

Q: Can METROZIDE GEL be applied around eyes?

A: No. METROZIDE GEL should not be applied around the eyes. As the areas around the eyes are highly sensitive, keep this medicine away from your eyes or eyelids. In case of accidental contact, rinse your eyes with plenty of warm water. If irritation persists, contact your doctor for advice.

Q: What should I do if I forgot to use METROZIDE GEL?

A: METROZIDE GEL should be used regularly starting from the first day of management. If you forgot to apply this medicine at the stipulated time, apply it as soon as you remember. However, it is time for next application, skip the missed application and continue with next application at regular times. Do not apply too much of medicine at a time with a view of compensating the missed application, as this could cause skin irritation.

Q: Can METROZIDE GEL manage acne?

A: Yes. METROZIDE GEL helps to control infection and inflammatory lesions associated with acne.

Q: Do I need prescription for METROZIDE GEL?

Yes. METROZIDE GEL is a prescription medicine which needs to be used only if prescribed by the physician. Kindly consult your doctor before using it.

References

1. KD. Tripathi. Macrolide and other antibacterial antibiotics. Anti-amoebic and other antiprotozoal drugs. Essentials of Medical Pharmacology. 7th Edition. Page – 763 & 837.

2. Weir CB, JK. Metronidazole. StatPearls. NIH. National Library of Medicine. National Center for Biotechnology Information. PMC. PubMed Central. June 2022. [Accessed on 20th March 2023] https://www.ncbi.nlm.nih.gov/books/NBK539728/

3. Galderma Laboratories. Metrogel 0.75% w/w Gel. Metronidazole Gel. Electronic Medicines Compendium. [Revised in February 2022]. [Accessed on 20th March 2023] https://www.medicines.org.uk/emc/files/pil.922.pdf

4. Galderma Laboratories. Metronidazole Gel. Dailymed.com. [Revised in March 2022]. [Accessed on 20th March 2023] https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=ab3a8a2d-714a-4beb-af8a-99bc3ac3ebbe

5. Leeford Healthcare Ltd. Metnizid. [Accessed on 20th March 2023] https://www.leeford.in/product/1400/metnizid