Introduction About LABEVAC 100 TABLET

LABEVAC 100 TABLET contains Labetalol which belongs to the group of medicines called Alpha, Beta Adrenergic Antagonists. It is used to manage hypertension and angina. It can also be used to control hypertension among pregnant women.

Hypertension (also known as high blood pressure) is a medical condition in which the force of the blood exerted against the walls of the artery remains very high and as a result it may lead to severe damage to the blood vessels supplying vital organs, such as heart, kidney or brain. If left unmanageed, it may cause serious complications such as heart attack, heart failure, stroke or even blindness.

Angina pectoris is a type of chest pain caused due to an inadequate supply of oxygen to the heart muscle. Symptoms include severe chest pain, tightness or heaviness with dizziness, fatigue, sweating, shortness of breath and fast heart rate.

Before taking LABEVAC 100 TABLET inform your doctor if you have any liver or kidney problems. You must also inform your doctor if you have any other types of anginas (such as Prinzmetal angina), psoriasis, diabetes or if you are scheduled for any surgery (including cataract surgery) in the upcoming days as a precaution.

LABEVAC 100 TABLET is not recommended for use in patients with asthma, hypotension (low blood pressure) or shock. It is also not suitable for use in patients with heart block, history of heart attack or heart failure.

LABEVAC 100 TABLET should be used in pregnant or breastfeeding women only if considered necessary by the physician. Therefore, consult your doctor before taking it.

The most common side effects of taking LABEVAC 100 TABLET are difficulty in passing urine, problems in erection or ejaculation, dizziness and tingling sensation in the scalp. Consult your doctor if any of these side effect troubles you.

Uses Of LABEVAC 100 TABLET

• Manage hypertension (including high blood pressure during pregnancy)
• Manage angina (chest pain)

How LABEVAC 100 TABLET Works

LABEVAC 100 TABLET is an alpha, beta-blocker. It works by blocking the actions of certain chemical messengers (such as adrenaline and noradrenaline) in our body that controls the functions of the heart, brain, kidneys and lungs. This action relaxes the blood vessels supplying the heart and improves blood flow and oxygen supply within them which helps in reducing chest pain (angina). It also reduces the strain on the heart and helps the heart to pump blood more efficiently with less pressure.

How to use LABEVAC 100 TABLET

Take LABEVAC 100 TABLET as directed by your physician. Swallow the medicine with a glass of water. Do not crush or chew the medicine. Try to take LABEVAC 100 TABLET at the same time each day. It is preferable to be taken after meals.

Your doctor will decide the correct dose and duration of therapy for you depending upon your age, body weight and health condition. Do not stop taking LABEVAC 100 TABLET unless advised by your doctor.

Side Effects Of LABEVAC 100 TABLET

How To Manage Side Effects

Dizziness:

Try to rest and relax. Get enough sleep. Avoid driving or operating any tools or machines completely while you are feeling dizzy. Do not consume excessive alcohol, as it could aggravate your dizziness. Consult your doctor if your dizziness worsens.

Warning & Precautions

Pregnancy

LABEVAC 100 TABLET should be used during pregnancy only if considered necessary by the physician. Therefore, consult your doctor before taking it.

Breastfeeding

LABEVAC 100 TABLET may excrete in breast milk. Therefore, it should be used in breastfeeding women only if considered necessary by the physician. Consult your doctor for advice before taking it.

Driving and Using Machines

Do not drive or operate any heavy tools or machines if you feel dizzy or tired after taking LABEVAC 100 TABLET.

Alcohol

Avoid consumption of alcohol while taking LABEVAC 100 TABLET as it might make you feel dizzier and drowsier.

Kidney

LABEVAC 100 TABLET should be used with caution in patients with kidney problems. Therefore, consult your doctor before taking it.

Liver

LABEVAC 100 TABLET should be used with caution in patients with liver problems. Therefore, consult your doctor before taking it.

Allergy

Do not take LABEVAC 100 TABLET if you are allergic to labetalol.

Lungs

LABEVAC 100 TABLET is not recommended to use in patients with a history of asthma, wheezing or any lung diseases. Therefore, consult your doctor before taking it.

Heart Disease

LABEVAC 100 TABLET is not recommended for use in patients with heart problems (such as slow heart rate, heart failure, heart block or heart rhythm disorder). Therefore, consult your doctor before taking it.

Interactions

A. Drug-Drug interactions:

Before taking LABEVAC 100 TABLET, inform your doctor if you are taking any of the following medicines such as:

• other medicines used in the management of hypertension and other heart problems (Ex. nifedipine, nisoldipine, nicardipine, isradipine, lacidipine, verapamil, diltiazem, hydralazine, clonidine, enalapril, lisinopril, ramipril, disopyramide, quinidine, amiodarone, isoprenaline, dobutamine, propafenone and digoxin)
• other beta-blockers (used to manage heart problems) Ex. atenolol, propranolol
• medicines used to manage diabetes (Ex. insulin, metformin)
• adrenaline (a medicine that can stimulate the heart)
• medicine used to relieve pain and inflammation (Ex. ibuprofen, indomethacin, hydrocortisone)
• medicines used to manage migraine headaches (Ex. ergotamine, dihydroergotamine or rizatriptan)
• medicine used in the management of mental illness (Ex. chlorpromazine, thioridazine, haloperidol)
• cimetidine, aluminium hydroxide gel (medicine used for stomach problems)
• barbiturates (medicine used to reduce anxiety and to induce sleep) Ex. phenobarbitone, pentobarbitone
• medicines used to manage depression (Ex. isocarboxazid, phenelzine, Selegiline, fluvoxamine and Tranylcypromine, amitriptyline)
• medicines used to manage malaria (Ex. mefloquine or quinine)
• alprostadil (a medicine used to manage impotence)
• moxisylyte (a medicine used to manage Raynaud’s disease)
• aldesleukin (a medicine used to manage secondary cancer of the kidney)
• contraceptive pills (birth control pills) Ex. ethinylestradiol

Overdosage:

If you or anyone else accidentally took more LABEVAC 100 TABLET, consult your doctor immediately or visit the nearby hospital. Symptoms of overdose might include slow heartbeat, low blood pressure, breathing difficulties and decrease in blood sugar which can cause sweating and confusion.

Synopsis

More Information

• Keep LABEVAC 100 TABLET out of reach of children
• Store LABEVAC 100 TABLET at room temperature

FAQs About LABEVAC 100 TABLET

Can LABEVAC 100 TABLET used in asthmatic patients?

No, LABEVAC 100 TABLET cannot be used in patients suffering from asthma. This is because using it can cause breathing problems, which may trigger an asthma attack. Always inform your doctor if you have or ever had asthma or any kind of difficulty breathing difficulty, before starting management with LABEVAC 100 TABLET.

Does LABEVAC 100 TABLET make you feel sleepy?

LABEVAC 100 TABLET may occasionally can cause dizziness or tiredness while taking it. Don't drive, use machinery or perform any activities that require alertness. If this occurs to you, consult your doctor for opinion.

Should we take LABEVAC 100 TABLET before or after food?

LABEVAC 100 TABLET should preferably be taken with meals. It should be swallowed with a drink of water.

When can I expect relief in my symptoms after taking LABEVAC 100 TABLET?

LABEVAC 100 TABLET usually starts working within a few hours of taking it. However, to notice considerable changes in the symptoms of high blood pressure or heart conditions, it may take a week. You will not be able to notice any difference, but that does not mean it is not working. However, keep taking LABEVAC 100 TABLET as prescribed by your doctor to get its full benefits.

What are the uses of LABEVAC 100 TABLET?

LABEVAC 100 TABLET It is used to manage hypertension and angina. It can also be used to manage high blood pressure during pregnancy.

What type of a medicine is LABEVAC 100 TABLET?

LABEVAC 100 TABLET is an alpha, beta-blocker. It works by blocking the actions of certain chemical messengers (such as adrenaline and noradrenaline) in our body that controls the functions of the heart, brain, kidneys and lungs. This action relaxes the blood vessels supplying the heart and improves blood flow and oxygen supply within them which helps in reducing chest pain (angina). It also reduces the strain on the heart and helps the heart to pump blood more efficiently with less pressure.

What happens when I stop taking LABEVAC 100 TABLET?

Do not stop taking LABEVAC 100 TABLET without consulting your doctor as your symptoms may re-appear once again. Make sure to take LABEVAC 100 TABLET for the stipulated duration recommended by your doctor to achieve maximum results.

What is the best time to take LABEVAC 100 TABLET?

LABEVAC 100 TABLET is preferably taken with meals. Your doctor will decide the best time for you to take LABEVAC 100 TABLET based on your age, body weight and disease condition.

What to do if I forgot to take a dose of LABEVAC 100 TABLET?

If you forgot to take a dose of LABEVAC 100 TABLET, take it as soon as you remember. However, if it is time for the next dose of LABEVAC 100 TABLET, skip the missed dose and take the next one regularly. Do not take a double dose of LABEVAC 100 TABLET to compensate the missed ones.

What precautions should be followed while taking LABEVAC 100 TABLET?

Before taking LABEVAC 100 TABLET inform your doctor if you have any liver or kidney problems. You must also inform your doctor if you have any other types of anginas (such as Prinzmetal angina), psoriasis, diabetes or if you are scheduled for any surgery (including cataract surgery) in the upcoming days as a precaution. LABEVAC 100 TABLET is not recommended for use in patients with asthma, hypotension (low blood pressure) or shock. It is also not suitable for use in patients with heart block, history of heart attack or heart failure. Do not take LABEVAC 100 TABLET without consulting your doctor if you are pregnant or breastfeeding. Regularly visit your doctor and take all the necessary blood test recommended by your doctor without fail.

Can I consume alcohol while taking LABEVAC 100 TABLET?

Avoid consumption of alcohol while taking LABEVAC 100 TABLET as it might make you feel dizzier and drowsier.

What happens if I accidentally take more LABEVAC 100 TABLET?

If you or anyone else accidentally took more LABEVAC 100 TABLET, consult your doctor immediately or visit the nearby hospital. Symptoms of overdose might include slow heartbeat, low blood pressure, breathing difficulties and decrease in blood sugar levels causing sweating and confusion.

Can I take LABEVAC 100 TABLET daily?

Take LABEVAC 100 TABLET as advised by your physician. Your doctor will evaluate your health condition and suggests whether can you take LABEVAC 100 TABLET every day or not.

Is LABEVAC 100 TABLET safe to use in diabetic patients?

LABEVAC 100 TABLET may alter the blood sugar levels in your body. Therefore, it is necessary to inform your doctor if you have diabetes before taking LABEVAC 100 TABLET as a precaution. Your doctor will closely monitor you blood sugar levels to avoid the risk of side effects.

What are the side effects of LABEVAC 100 TABLET?

The most common side effects of taking LABEVAC 100 TABLET are difficulty in passing urine, problems in erection or ejaculation, dizziness and tingling sensation in the scalp. Consult your doctor if any of these side effect troubles you.

Can I stop taking LABEVAC 100 TABLET once my symptoms subside?

No. Do not stop taking LABEVAC 100 TABLET without consulting your doctor as it may make your symptoms reappear. Therefore, take LABEVAC 100 TABLET as advised by your doctor for the stipulated duration.

Can LABEVAC 100 TABLET be taken during pregnancy?

LABEVAC 100 TABLET should be used during pregnancy only if considered necessary by the physician. Therefore, consult your doctor before taking it.

Is LABEVAC 100 TABLET safe to use in kidney disease?

LABEVAC 100 TABLET should be used with caution in patients with kidney problems. Your doctor will access your health condition and suggest a suitable dose for you.

Can the use of LABEVAC 100 TABLET affect the liver?

Yes. LABEVAC 100 TABLET may affect the way your liver work. It can elevate the levels of certain liver enzymes in your body. Therefore, it should be used with caution in patients with liver problems. Consult your doctor before taking it.

Can the use of LABEVAC 100 TABLET affect my sexual life?

LABEVAC 100 TABLET may cause problems in erection and ejaculation in some individuals. Consult your doctor if it troubles you.

References

1. KD. Tripathi. Adrenergic drugs and drugs acting on glaucoma. Essentials of medical pharmacology. 7th Edition. 2019. Page –151.

2. Louise M. Webster, Jenny E. Myers, Catherine Nelson-Piercy, Kate Harding, J. Kennedy Cruickshank, Ingrid Watt-Coote, Asma Khalil, Cornelia Wiesender, Paul T. Seed and Lucy C. Chappell. Labetalol Versus Nifedipine as Antihypertensive Treatment for Chronic Hypertension in Pregnancy. Journal of Hypertension. September 2017. [Accessed on 9th November 2022] https://www.ahajournals.org/doi/10.1161/hypertensionaha.117.09972

3. Prof Thomas Easterling, MD, Prof Shuchita Mundle, MD, Hillary Bracken, PhD, Seema Parvekar, MD, Sulabha Mool, DGO, Prof Laura A Magee, MD, Prof Peter von Dadelszen, Dphil Tara Shochet, PhD, Prof Beverly Winikoff, MD. Oral antihypertensive regimens (nifedipine retard, labetalol and methyldopa) for management of severe hypertension in pregnancy: an open label, randomized controlled trial. The Lancet. September 2019. [Accessed on 9th November 2022] https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(19)31282-6/fulltext

4. Mylan Laboratories Limited. Electronic Medicines Compendium (EMC). [Revised in January 2022]. [Accessed on 9th November 2022] https://www.medicines.org.uk/emc/files/pil.2648.pdf

Useful Diagnostic Tests

• Kidney Function Test

Author Details

Written By Srilekha. R - B.Pharm

Reviewed By Dr. Sankara Babu Gorle - MBBS, MD(Pharmacology) View profile

Last updated on 10 Nov 2022 | 02:26 PM(IST)