Introduction About INCYST M TABLET

INCYST M TABLET contains a combination of Metformin and Myo Inositol, which belong to groups of medicines called antidiabetic agents and nutritional supplements, respectively. It is used in the management of polycystic ovarian syndrome (PCOS) in women. Polycystic ovarian syndrome is a hormonal disorder among women of reproductive age that causes the ovaries to enlarge, which manages the release of eggs at regular intervals. The symptoms may include menstrual irregularity, excess hair growth, acne, weight gain, etc.

While taking INCYST M TABLET, your doctor will monitor your blood sugar level, and kidney functions at regular intervals. During the course of management with INCYST M TABLET, your doctor may advise regular monitoring of blood sugar levels and kidney function. Before taking INCYST M TABLET, inform your doctor if you have liver, kidney, lung, or heart problems or should undergo any surgery. Do not consume alcohol while taking INCYST M TABLET as it can worsen the side effects.

Inform your doctor if you are pregnant or breastfeeding before taking this medicine. INCYST M TABLET is not recommended for use by children. The most common side effects of taking INCYST M TABLET are nausea, changes in taste, diarrhoea, dizziness, stomach pain, and loss of appetite.

Uses Of INCYST M TABLET

• To manage polycystic ovarian syndrome (PCOS) in women

How INCYST M TABLET Works

INCYST M TABLET is a drug that combines metformin and myo-inositol. Metformin enhances the body's sensitivity to insulin by decreasing the level of circulating insulin and producing a positive effect on the accumulated adipose (fat) tissue. Myo-inositol works by reducing insulin resistance and regulating hormonal imbalances. These types of actions aid in the control of polycystic ovarian syndrome symptoms and the regulation of the menstrual cycle. 

How to use INCYST M TABLET

Take INCYST M TABLET as advised by your physician. Swallow the medicine with water. Do not crush or chew the medicine. Your doctor will decide the right dose and duration depending on your age, body weight, and disease condition.

Side Effects Of INCYST M TABLET

How To Manage Side Effects

Diarrhea

Drink lots of fluids, such as water or fruit juice, to keep yourself hydrated. Consult your doctor if your symptoms don’t improve.

Loss Of Appetite

Eat when you are hungry. Eat a nutritious snack rich in calories and protein, such as dried fruit and nuts. If your symptoms do not improve, see your doctor. 

Nausea And Vomiting

Stick to simple meals. Avoid eating oily or spicy foods. If your symptoms do not improve, consult your doctor.

Stomach Pain

Try to have smaller and more frequent meals. Keep a heating pad on your stomach. If the symptom does not improve, consult your doctor.

Warning & Precautions

Pregnancy

Consult your doctor

The safety and effectiveness of INCYST M TABLET for use by pregnant women are not established. Consult your doctor before taking it.

Breastfeeding

Contraindicated

INCYST M TABLET is not recommended for use by breastfeeding women. Consult your doctor before taking it.

Driving and Using Machines

Use with Caution

Avoid driving or using heavy machines if you feel weak, dizzy, have profuse sweating, faster heartbeat, have vision problems or have concentrating difficulties after taking INCYST M TABLET.

Alcohol

Consult your doctor

Do not consume alcohol while taking INCYST M TABLET as it can increase the impact of side effects.

Kidney

Consult your doctor

INCYST M TABLET is not recommended for use in patients with severe kidney disease. It should be used with caution in patients with mild to moderate kidney disease. Consult your doctor before taking it.

Liver

Consult your doctor

INCYST M TABLET is not recommended for use in patients with severe liver diseases. INCYST M TABLET should be used with caution in patients with mild to moderate liver disease. Consult your doctor before taking it.

Allergy

Contraindicated

Do not take INCYST M TABLET if you are allergic to Metformin or Myo Inositol.

Lungs

Contraindicated

INCYST M TABLET is not recommended for use in patients with a severe lung infection. Consult your doctor before taking it.

Heart Disease

Contraindicated

INCYST M TABLET is not recommended for use in patients with acute heart failure, who recently had a heart attack, severe problems with circulation (such as shock), or who have breathing difficulties. Consult your doctor before taking it.

Use In Pediatrics

Contraindicated

INCYST M TABLET is not recommended for use by children. Consult your doctor before taking it.

Use In Geriatrics

Consult your doctor

Your doctor will decide the right dose depending on your kidney tests and disease condition. Consult your doctor before taking [GBNKEYORD].

Interactions

A. Drug-Drug interactions:

Before taking INCYST M TABLET, inform your doctor if you are taking any of the following medicine:

• medicines used to manage high blood pressure (Ex. propranolol, metoprolol)
• Medicines used in depression management (Ex. fluoxetine, amitriptyline)
• cholesterol-lowering agents (Ex. cholestyramine)
• fluorouracil (used in cancer management)
• sulfasalazine (used to manage stomach or duodenum ulcers)
• medicines used to relieve pain and inflammation (Ex. ibuprofen, celecoxib)
• medicine used to manage heart conditions (Ex. digoxin, digitalis)
• medicines used to provide relief from inflammation (Ex. prednisone, hydrocortisone)

Overdosage:

If you or anyone else accidentally take too much of INCYST M TABLET, consult your doctor immediately or visit the nearby hospital. Symptoms of overdose are lactic acidosis (vomiting, stomachache, muscle cramps, tiredness, difficulty breathing, reduced body temperature and heartbeat) as this condition may lead to coma.

Synopsis

More Information

• Keep INCYST M TABLET out of reach from children
• Store below 25°C

FAQs About INCYST M TABLET

Q: What is INCYST M TABLET used for?

A: INCYST M TABLET is used to manage polycystic ovarian syndrome (PCOS) in women. Polycystic ovary syndrome (PCOS) is a hormonal disorder in women where the ovaries may develop numerous small collections of fluid (follicles) and fail to regularly release eggs.

Q: Can INCYST M TABLET be used in patients with kidney disease?

A: No, INCYST M TABLET is not recommended for use in patients with severe kidney disease. Patients with mild to moderate disease should take this medicine with caution, and regular monitoring of kidney function is needed, especially in the elderly.

Q: How does INCYST M TABLET work?

A: INCYST M TABLET helps your body to utilise insulin and regulate menstrual cycles. Metformin decreases glucose production in the liver and improves insulin sensitivity. Myo-inositol increases insulin sensitivity (body cells utilise insulin effectively to produce glucose) and decreases hyperandrogenism (levels of the male hormone androgen are reduced).

Q: What if I take more of INCYST M TABLET?

A: If you or anyone else takes more INCYST M TABLET, consult your doctor right away because you could develop lactic acidosis (vomiting, stomach-ache, muscle cramps, tiredness, difficulty breathing, reduced body temperature, and decreased heartbeat) and end up in a coma.

Q: Can I consume alcohol or drive while taking INCYST M TABLET?

A: No, do not consume alcohol while taking INCYST M TABLET as it can increase the side effects, and do not drive or use machines as it can make you feel dizzy or sleepy, which affects your ability to drive.

References

1. KD Tripathi. Insulin, Oral Antidiabetic Drugs and Glucagon. Essentials of medical pharmacology. Eighth Edition. 2019. Page –299-300.

2. Philippe Merviel, Pandora James, Sarah Bouée, Mathilde Le Guillou, Camille Rince, Charlotte Nachtergaele & Véronique Kerlan. Impact of myo-inositol treatment in women with polycystic ovary syndrome in assisted reproductive technologies [Revised in January 2021] [Accessed on 21st June 2022] https://reproductive-health-journal.biomedcentral.com/articles/10.1186/s12978-021-01073-3

3. R Dumitrescu, C Mehedintu, I Briceag, VL Purcarea, and D Hudita. Metformin-Clinical Pharmacology in PCOs. [Accessed on 21st June 2022] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4392089/

4. Milpharm Limited. Electronic Medicines Compendium (EMC). [Revised in June 2020] [Accessed on 21st June 2022] https://www.medicines.org.uk/emc/files/pil.594.pdf

5. Myo inositol. Drugs.com. [Accessed on 27th June 2022] https://www.drugs.com/ingredient/inositol.html

Useful Diagnostic Tests

• Blood tests
• Kidney function test

Author Details

Written By Dr. N. Sai Swaroop - Pharm.D

Reviewed By Dr. Sankara Babu Gorle - MBBS, MD(Pharmacology) View profile

Last updated on 12 Dec 2023 | 11:33 AM(IST)