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Introduction About GLUCORYL MV 2/0.2MG TABLET
GLUCORYL MV 2/0.2MG TABLET is used in adults to manage type 2 diabetes mellitus when diet, exercise, and single-agent or second-line therapy with two drugs are insufficient to adequately control blood sugar levels. It contains a combination of three medicines namely, Glimepiride, Metformin and Voglibose, which works by making your body absorb circulating blood glucose levels.
Take GLUCORYL MV 2/0.2MG TABLET as advised by your physician. Swallow the medicine with a glass of water. Do not crush or chew the medicine.
GLUCORYL MV 2/0.2MG TABLET is not recommended for use in patients allergic to glimepiride, metformin, voglibose, and/or other sulfonylureas or sulphonamides. It is also not recommended for use in patients with acute conditions (such as dehydration or severe infection), severe ketosis (a severe complication of diabetes), severe trauma, lung problems (such as acute or chronic respiratory failure), heart problems (such as acute or chronic cardiac failure or recent myocardial infarction), and/or severe kidney or liver problems. Before taking GLUCORYL MV 2/0.2MG TABLET, inform your doctor if you recently had trauma and/or have febrile infections, fever, uncontrolled diabetes, hypothyroidism (underactive thyroid), chronic intestinal disease, fever, or other kidney or liver problems.
GLUCORYL MV 2/0.2MG TABLET is not recommended for use in pregnant and breastfeeding women since it may cause harm to the developing fetus or nursing child. GLUCORYL MV 2/0.2MG TABLET is also not recommended for use in children and adolescents (aged below 18 years) and is advised to be used with caution in elderly patients (aged 75 years or older) after consulting the doctor.
The most common side effects of GLUCORYL MV 2/0.2MG TABLET are nausea and vomiting, diarrhea, abdominal pain, loss of appetite, metallic taste, and/or hypoglycemia (low blood sugar).
Uses Of GLUCORYL MV 2/0.2MG TABLET
How GLUCORYL MV 2/0.2MG TABLET Works
GLUCORYL MV 2/0.2MG TABLET contains a combination of three medicines namely, glimepiride, metformin, and voglibose. Each of these drugs works in a different way to help lower blood sugar:
- Glimepiride: It stimulates the pancreas to release more insulin, which helps lower blood sugar by allowing cells to take in glucose.
- Metformin: It decreases the amount of glucose produced by the liver and improves the sensitivity of muscle cells to insulin, allowing them to use glucose more effectively.
- Voglibose: It inhibits enzymes in the gut that break down carbohydrates into glucose, slowing down the absorption of sugar from food.
Together, these actions help control blood sugar levels throughout the day by improving insulin secretion, reducing glucose production, and slowing sugar absorption.
How to use GLUCORYL MV 2/0.2MG TABLET
- Take GLUCORYL MV 2/0.2MG TABLET under medical supervision. It can be taken once or twice daily with meals, depending on your doctor’s advice
- Taking it with food helps reduce stomach upset and ensures proper absorption of the medication.
- The tablet should be swallowed whole with water. Do not crush, chew, or break the tablet as this can affect how the medication is absorbed.
- Since glimepiride stimulates insulin release, make sure to eat meals regularly to avoid hypoglycemia (low blood sugar).
- Do not adjust the dose or stop taking the medication without consulting your healthcare provider.
- Always follow your doctor's specific instructions, and regularly monitor your blood sugar levels as advised.
Side Effects Of GLUCORYL MV 2/0.2MG TABLET
Common Side Effects of GLUCORYL MV 2/0.2MG TABLET:
- Nausea, vomiting, diarrhea, abdominal pain, and loss of appetite
- Metallic taste
- Hypoglycaemia (low blood sugar)
Stop taking GLUCORYL MV 2/0.2MG TABLET and contact your doctor immediately if you experience any of the following side effects:
- Severe hypoglycemia (very low blood sugar level)
- Signs of lactic acidosis (lactic acid built up in the bloodstream) such as exhaustion or extreme fatigue, body weakness, diarrhea, and/or headache
Warning & Precautions
Pregnancy
ContraindicatedGLUCORYL MV 2/0.2MG TABLET is not recommended for use during pregnancy since it may cause harm to the fetus.
Breastfeeding
ContraindicatedGLUCORYL MV 2/0.2MG TABLET is not recommended for use in breastfeeding women since the medicine may pass through breast milk and may cause harm to the nursing child.
Driving and Using Machines
Use with CautionDo not drive or operate any machines if you experience impaired alertness or reactions (due to hypoglycemia) while taking GLUCORYL MV 2/0.2MG TABLET.
Alcohol
ContraindicatedDo not consume alcohol while taking GLUCORYL MV 2/0.2MG TABLET since it may reduce your blood sugar level.
Kidney
Consult your doctorGLUCORYL MV 2/0.2MG TABLET is not recommended in patients with severe renal failure. It should be used with caution in patients with other kidney diseases.
Liver
Consult your doctorGLUCORYL MV 2/0.2MG TABLET is not recommended for use in patients with severe liver disease. It should be used with caution in patients with other liver diseases.
Allergy
ContraindicatedDo not take GLUCORYL MV 2/0.2MG TABLET if you are allergic to glimepiride, metformin, voglibose, other sulfonylureas/sulphonamides, and/or any other ingredients of this medicine.
Lungs
ContraindicatedGLUCORYL MV 2/0.2MG TABLET is not recommended for use in patients with lung problems such as acute or chronic respiratory failure.
Heart Disease
ContraindicatedGLUCORYL MV 2/0.2MG TABLET) is not recommended in patients with heart problems such as acute or chronic cardiac failure or recent myocardial infarction.
Use In Pediatrics
ContraindicatedGLUCORYL MV 2/0.2MG TABLET is not recommended for use in children and adolescents (aged below 18 years) since the safety and effectiveness of the medicine are not established.
Use In Geriatrics
Use with CautionGLUCORYL MV 2/0.2MG TABLET should be used with caution in elderly patients (aged 65 years and above).
Others
GLUCORYL MV 2/0.2MG TABLET is not recommended for use if you:
- Suffer from any acute type of metabolic acidosis (the buildup of excess acid in the body), such as lactic acidosis, diabetic ketoacidosis, and/or diabetic precoma
- Suffer from acute conditions such as dehydration, severe infection, and shock
- Have severe ketosis (a severe complication of diabetes)
- Are in a state of diabetic coma
- Had severe infections before or after the operation
- Had severe trauma
- Have gastrointestinal obstruction
Before taking GLUCORYL MV 2/0.2MG TABLET, inform your doctor if you:
- Recently had trauma
- Had or scheduled for any surgery
- Suffer from febrile infections, fever, and/or uncontrolled diabetes
- Are undernourished and/or have irregular mealtimes or skipped meals
- Suffer from an imbalance between physical exertion and carbohydrate intake
- Have hypothyroidism (underactive thyroid)
- Have a history of laparotomy (a surgical incision done into the abdominal cavity for diagnosing a condition) and/or ileus (interrupted movement of the intestines)
- Suffer from chronic intestinal disease (accompanied by disturbances in digestion and absorption)
- Suffer from fever
Interactions
A. Drug-Drug interactions:
Before taking GLUCORYL MV 2/0.2MG TABLET, inform your doctor if you are taking any of the following medicines:
- Antibacterials (Ex. rifampicin, ciprofloxacin, clarithromycin, sulfacetamide, minocycline, and chloramphenicol)
- Antifungals (Ex. fluconazole, isavuconazole, and miconazole)
- Oral antidiabetics and insulin (medicines used to manage high blood sugar) Ex. glipizide, glyburide diazoxide
- Anticancer (Ex. cyclophosphamide, trofosfamide, vandetanib, crizotinib, olaparib)
- Disopyramide (medicine used to manage an irregular heartbeat)
- Fenyramidol (a medicine used to relax muscles)
- Pentoxifylline (a medicine used to improve blood flow through the arteries)
- Medicine used to manage joint pain (Ex. phenylbutazone, oxyphenbutazone, and probenecid sulfinpyrazone)
- Corticosteroids (Ex. prednisolone, methylprednisolone)
- Diuretics (Ex. Furosemide)
- Laxatives (Ex. Bisacodyl)
- Phenytoin and fenfluramine (medicines used to manage seizures)
- Dolutegravir (a medicine used to manage HIV infection)
- Antidepressants (Ex. phenelzine, selegiline)
- alpha blockers (Ex. doxazosin, prazosin)
- Anticoagulants (Ex. Warfarin)
Overdosage:
If you or anyone else accidentally takes too much of GLUCORYL MV 2/0.2MG TABLET, consult your doctor immediately or visit the nearby hospital. Symptoms of overdose are hypoglycemia (low blood sugar), lactic acidosis, pancreatitis (inflammation of the pancreas), abdominal discomfort, and/or diarrhea.
Synopsis
| Drug | : | Glimepiride, Metformin, Voglibose |
| Pharmacological Category | : | Antidiabetic Agents |
| Therapeutic Indication | : | Type II diabetes mellitus |
| Dosage Forms | : | Tablet |
More Information
To know more about this medicine:
FAQs About GLUCORYL MV 2/0.2MG TABLET
Q: What is GLUCORYL MV 2/0.2MG TABLET used for?
A: GLUCORYL MV 2/0.2MG TABLET is used in adults to manage type 2 diabetes mellitus when diet, exercise, and single-agent or second-line therapy with two drugs are insufficient to adequately control blood sugar levels.
Q: How does GLUCORYL MV 2/0.2MG TABLET work?
A: Glimepiride lowers blood glucose levels by increasing the amount of insulin released by the pancreas. Metformin works by decreasing glucose production in the liver and the amount of glucose absorbed by the stomach and intestine. Voglibose works by inhibiting the alpha-glucosidase enzyme, which breaks down complex carbohydrates into simple sugars. This leads to a reduction in blood glucose levels in individuals with type 2 diabetes mellitus.
Q: What are the side-effects of GLUCORYL MV 2/0.2MG TABLET?
A: The most common side-effects of GLUCORYL MV 2/0.2MG TABLET are nausea and vomiting, diarrhea, abdominal pain, loss of appetite, metallic taste, and/or hypoglycemia (low blood sugar).
Q: How do I take GLUCORYL MV 2/0.2MG TABLET?
A: Take GLUCORYL MV 2/0.2MG TABLET as advised by your physician. It is preferably taken with meals to avoid stomach upset. Swallow the medicine with a glass of water. Do not crush or chew the medicine.
Q: What happens if GLUCORYL MV 2/0.2MG TABLET is taken at more than its required dosage?
A: If you or anyone else accidentally takes too much of GLUCORYL MV 2/0.2MG TABLET, symptoms of hypoglycemia (low blood sugar), lactic acidosis, pancreatitis (inflammation of the pancreas), abdominal discomfort, and/or diarrhea may occur.
Q: Can GLUCORYL MV 2/0.2MG TABLET be used in pregnancy?
A: No, GLUCORYL MV 2/0.2MG TABLET is not recommended for use during pregnancy since it may cause harm to the fetus.
Q: Who should not take GLUCORYL MV 2/0.2MG TABLET?
A: GLUCORYL MV 2/0.2MG TABLET is also not recommended for use in patients with acute conditions (such as dehydration or severe infection), severe ketosis, severe trauma, lung problems, heart problems and/or severe kidney or liver problems.
Q: Can GLUCORYL MV 2/0.2MG TABLET be used in children?
A: No, GLUCORYL MV 2/0.2MG TABLET is not recommended for use in children and adolescents (aged below 18 years).
References
1. KD Tripathi. Insulin, Oral Hypoglycaemic Drugs and Glucagon. Essentials of Medical Pharmacology. Seventh Edition. 2019. Page – 270, 275, 277.
2. Kalra S, Das AK, Priya G, Ghosh S, Mehrotra RN, Das S, Shah P, Bajaj S, Deshmukh V, Sanyal D, Chandrasekaran S, Khandelwal D, Joshi A, Nair T, Eliana F, Permana H, Fariduddin MD, Shrestha PK, Shrestha D, Kahandawa S, Sumanathilaka M, Shaheed A, Rahim AA, Orabi A, Al-Ani A, Hussein W, Kumar D, Shaikh K. Fixed-dose combination in management of type 2 diabetes mellitus. NIH National Library of Medicine. National center for biotechnology information. PMC PubMed Central. [Revised in November 2020] [Accessed on 26th November 2022] click here
3. Windlas Biotech Private Limited. Amaryl MV 1mg, Amaryl MV 2mg. [Revised in March 2021] [ [Accessed on 26th November 2022] click here
4. Primus Remedies Pvt. Ltd. Voglow GM1 Fort. [Accessed on 26th November 2022] click here
5. Eris Lifesciences. Glimisave MV 1.3 F, Glimisave MV 2 forte, Glimisave MV 3.3, Glimisave MV 3.3 F. [Accessed on 26th November 2022] click here
6. Leeford Healthcare Ltd. VOGLIMET-GM FORTE. [Accessed on 26th November 2022] click here
7. Ikon Remedies Pvt. Ltd. Voglicon-GM Tablets. [Accessed on 26th November 2022] click here
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