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What is ENDOBLOC T?
- ENDOBLOC T contains Ambrisentan and Tadalafil
What ENDOBLOC T is used for?
- ENDOBLOC T is used to treat pulmonary arterial hypertension (PAH) in adults
- PAH is high blood pressure in the blood vessels (the pulmonary arteries) that carry blood from the heart to the lungs
Talk to Doctor
Pregnancy & Breast Feeding
Children & Adolescents
Driving & Using Machines
Talk to your doctor before taking this medicine, if you:
- are allergic to Ambrisentan, Tadalafil, soya, or any of the other ingredients of this medicine
- have scarring of the lungs, of unknown cause (idiopathic pulmonary fibrosis)
- have anaemia (a reduced number of red blood cells)
- have swelling in the hands, ankles or feet caused by fluid (peripheral oedema)
- suffer from lung disease where the veins in the lungs are blocked (pulmonary veno-occlusive disease)
- have heart problems such as angina (chest pain), heart failure, irregular heartbeats or have had a heart attack
- have low blood pressure or high blood pressure that is not controlled
- have had a stroke
- have kidney or liver problems
- have stomach ulcers
- have vision problem, including any damage to your optic nerve
- have ever had hearing problems such as ringing in the ears, dizziness or loss of hearing
- have a deformed penis shape or Peyronie’s disease
- have had an erection that lasted more than 4 hours
- have blood cell problems such as sickle cell anemia, multiple myeloma or leukemia
- Do not take ENDOBLOC T if you are pregnant or planning to become pregnant
- Do not breast-feed while you are taking this medicine
- ENDOBLOC T is not recommended for children and adolescents aged under 18 years as the safety and effectiveness is not established in this age group
- ENDOBLOC T may cause side effects, such as low blood pressure, dizziness, tiredness, that may affect your ability to drive or use machines
- Do not drive or use machines if you are feeling unwell
Tell your doctor if you are taking, have recently taken or might take any other medicines such as:
- cyclosporine (a medicine used after transplant or to treat psoriasis)
- rifampicin (an antibiotic used to treat tuberculosis)
- other medicines used to treat pulmonary hypertension such as iloprost, epoprostenol, sildenafil
- nitrates or guanylate cyclase stimulators
- medicines used to treat hypertension
- protease inhibitors, used to treat HIV infection, such as ritonavir
- ketoconazole, itraconazole (medicines used to treat fungal infection)
- phenobarbital, phenytoin, carbamazepine used to treat fits
- other medicines for erectile dysfunction (impotence)
- Always take this medicine exactly as your doctor has told you to
- Swallow the medicine with a glass of water
- Do not split, crush or chew the medicine
If you take more ENDOBLOC T
- If you take more ENDOBLOC T, you may be more likely to have side effects, such as headache, flushing, dizziness, nausea (feeling sick), or low blood pressure that could cause light-headedness
- Contact your doctor or go to nearest hospital immediately
If you forget to take ENDOBLOC T
- If you forget a dose of ENDOBLOC T, just take the medicine as soon as you remember, then carry on as before
- Do not take two doses at the same time to make up for a forgotten dose
If you stop taking ENDOBLOC T
- Do not stop taking ENDOBLOC T without your doctor's advice
Like all medicines, this medicine can cause side effects, although not everybody gets them.
- allergic reactions marked by rash or itching and swelling (usually of the face, lips, tongue or throat) which may cause difficulty in breathing or swallowing
- swelling (oedema), especially of the ankles and feet
- heart failure (this is due to the heart not pumping out enough blood, causing shortness of breath, extreme tiredness and swelling in the ankles and legs)
- decreased eyesight in one or both eyes
- sudden decrease or loss of hearing, sometimes with ringing in the ears and dizziness
- erection that lasts more than 4 hours (with or without pain)
- anaemia (reduced number of red blood cells) marked by tiredness, weakness, shortness of breath and generally feeling unwell
- hypotension (low blood pressure)
- flushing (redness of the skin)
- vomiting
- rash
- chest pain/discomfort
- blurry or other changes to vision
- fainting
- running nose
- constipation
- ringing in the ears (tinnitus)
- liver injury
- sudden hearing loss
- Store at room temperature (15-25ºC)
- Keep this medicine out of the reach of children
- Do not use this medicine after the expiry date
The contents of this website are for informational purposes only and not intended to be a substitute for professional medical advice, diagnosis, or treatment. Please seek the advice of a physician or other qualified health provider with any questions you may have regarding a medical condition. Do not disregard professional medical advice or delay in seeking it because of something you have read on this website.