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Introduction About DROTIN INJECTION
DROTIN INJECTION is an antispasmodic agent used for renal colic, biliary colic, smooth muscle spasm of bladder and urinary tract, menstrual cramps, abdominal cramps and other pain related to smooth muscles. It can also be used for cervical dilation during labour in some cases.
It contains a medicine called Drotaverine which works by relaxing the smooth muscles. Before taking DROTIN INJECTION, inform your doctor if you have any pre-existing liver, kidney or heart problems. You must also inform your doctor if you have asthma, allergic rhinitis, stomach ulcers or inflammation or if you are pregnant or breastfeeding as a precaution.
The most common side effects of taking this medicine are pain at injection site, dry mouth, dizziness, headache and irregular pulse rate. Consult your doctor if they trouble you.
How DROTIN INJECTION Works
DROTIN INJECTION contains a medicine called drotaverine which works by relaxing the smooth muscles in the body, especially those in the digestive and urinary systems. It does this by blocking an enzyme called phosphodiesterase (PDE-4), which leads to an increase in certain molecules that help muscles relax. This action helps to relieve pain and discomfort caused by muscle spasms, like those experienced in conditions such as cramps, stomach pain, or menstrual pain.
How to use DROTIN INJECTION
- DROTIN INJECTION should be used only under medical supervision
- It will be administered to you only by a doctor or a nurse into the vein or muscles
- The dosage and frequency depend on your medical condition and how your body responds to the treatment.
Side Effects Of DROTIN INJECTION
Common Side Effects of DROTIN INJECTION:
- Low blood pressure, dizziness
- Headache
- Dryness of mouth
- Slow or irregular pulse rate
- Pain at injection site
Warning & Precautions
Pregnancy
Use with CautionAnimal and human studies have not indicated any harm to the growing fetus. However, caution should be exercised before using this medicine in pregnant women.
Breastfeeding
Consult your doctorThere are no adequate data on the use of Drotaverine in lactation women. Therefore, consult your doctor before taking this medicine.
Driving and Using Machines
Use with CautionDo not drive or handle heavy machines if your ability is affected by this medicine.
Kidney
ContraindicatedStudies have shown that drotaverine can harm your kidneys. Therefore, this medicine is not recommended for use in patients with pre-existing kidney conditions.
Liver
Consult your doctorThis medicine is not suitable for use in patients with severe liver conditions. It should be used with caution in patients mild to moderate liver problems.
Allergy
ContraindicatedDo not take DROTIN INJECTION if you are allergic to drotaverine and mefenamic acid
Lungs
ContraindicatedThis medicine should not be used in patients suffering from allergic rhinitis, urticaria, or asthma.
Heart Disease
Consult your doctorThis medicine is not suitable for use in patients with severe heart conditions. It should be used with caution in patients mild to moderate heart problems.
Use In Pediatrics
SafeDrotaverine injections are suitable for use in children.
Use In Geriatrics
Use with CautionDROTIN INJECTION should be used with caution in elderly patients, especially with pre-existing illnesses.
Others
DROTIN INJECTION is not recommended for use in patients suffering from:
- Stomach ulcers or inflammation
- Porphyria
Interactions
Drug-Drug Interactions:
- Other spasmolytics
- Tricyclic antidepressants
- Quinidine and novocainamid (antiarrhythmics agent)
- morphine (a pain killer)
- antiparkinsonian (such as levodopa)
- analgesics, antimuscarinics or benzodiazepines
Overdosage:
DROTIN INJECTION will be given to you only by a doctor or nurse. Therefore, it is unlikely to receive an overdose. However, symptoms of overdose includes weakness, general feeling of discomfort, dizziness, vomiting, headache, etc.
Synopsis
| Drug | : | Drotaverine |
| Pharmacological Category | : | Antispasmodics |
| Therapeutic Indication | : | Smooth muscle cramps |
| Dosage Forms | : | Tablet, Injection, Suspension |
FAQs About DROTIN INJECTION
Q: What is DROTIN INJECTION used for?
A: This medicine is an antispasmodic agent used to provide relief from painful conditions such as menstrual pain, abdominal pain or any other pain related to smooth muscle. It is also used in the pain management of functional bowel disorders and alleviating pain in renal colic.
Q: How should I take DROTIN INJECTION?
A: This medicine will be given to you by a doctor or a nurse into the veins or muscles.
Q: Can I take DROTIN INJECTION during pregnancy?
A: It is important to consult your doctor before taking Drotaverine during pregnancy. Although it may be prescribed in certain cases, its safety must be evaluated on an individual basis.
Q: Are there any side effects of Drotaverine?
A: Some common side effects include nausea, headache, dizziness, and dry mouth. In rare cases, it may cause a drop in blood pressure or allergic reactions. If you experience any severe side effects, contact your doctor.
Q: Can I take DROTIN INJECTION with other medications?
A: Always inform your doctor about any other medications you are taking, as Drotaverine may interact with certain drugs, especially those for blood pressure or other muscle relaxants.
Q: How quickly does DROTIN INJECTION work?
A: This medicine typically starts to relieve pain within 30 minutes to 1 hour after taking it, depending on the condition and individual response.
Q: Is DROTIN INJECTION safe for long-term use?
A: Drotaverine is usually prescribed for short-term relief of pain due to muscle spasms. Long-term use should be guided by a healthcare professional to avoid potential risks.
References
- Efficacy and Safety of Drotaverine Hydrochloride in Irritable Bowel Syndrome: A Randomized Double-Blind Placebo-Controlled Study. PMC. PubMed Central. National Library of Medicine. National Center for Biotechnology Information. Nov-Dec 2014. [Accessed on 17th October 2024]. click here
- DRO SPAZ 40 mg/ 2 ml, solution for injection Drotaverine hydrochloride ADIPHARM LTD. [Revised in January 2019]. [Accessed on 17th October 2024]. click here
- Regulix 80. BDA HEALTHCARE PVT. LTD., [Revised in July 2023]. [Accessed on 17th October 2024]. click here
- Leeford Healthcare Pvt Ltd. 2024. [Accessed on 17th October 2024]. click here
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The contents of this website are for informational purposes only and not intended to be a substitute for professional medical advice, diagnosis, or treatment. Please seek the advice of a physician or other qualified health provider with any questions you may have regarding a medical condition. Do not disregard professional medical advice or delay in seeking it because of something you have read on this website.
