Introduction About DART

DART TABLET is a combination of Caffeine, Paracetamol, and Propyphenazone, belongs to a group of medicines called CNS stimulants, Analgesics, and Antipyretics, respectively. It is used to manage headaches, body aches, fevers, backaches, migraines, and dental pain.

Avoid smoking and consuming alcohol while taking DART TABLET. It is not recommended for use in patients with a deficiency of glucose-6-phosphate dehydrogenase, hemolytic anemia, or acute hepatic porphyria. Contact your doctor before taking.

DART TABLET should be used with caution in patients with asthma, chronic rhinitis, chronic urticaria, bone marrow dysfunction, liver disease, or kidney disease. Contact your doctor before taking.

DART TABLET is generally not recommended for use in pregnancy. Contact your doctor before taking.

DART TABLET is not recommended for use in breastfeeding women as it may pass through the breast milk. Contact your doctor before taking.

DART TABLET is not recommended for use in children and adolescents below 12 years of age. Contact your doctor before taking.

DART TABLET should be used with caution in elderly patients (aged 65 years or older). Contact your doctor before taking.

The most common side effects of this medicine are skin rashes and urticaria. Contact your physician if any of the symptoms worsen.

Uses Of DART

DART TABLET is used to manage:

• headache
• body ache
• fever
• backache
• migraine
• dental pain

How DART Works

DART TABLET helps with pain, where caffeine has a stimulating effect on the central nervous system by blocking adenosine receptors and improving alertness and drowsiness. Paracetamol is an analgesic and antipyretic that works by increasing the pain threshold by inhibiting COX-1 and COX-2 enzymes and also acts on the heat-regulating center of the brain, causing peripheral vasodilation, sweating, and loss of body heat. Propyphenazone works by blocking COX-1 and COX-2 enzymes, which are responsible for pain and inflammation.

How to use DART

Take this medicine as advised by your physician. Swallow this medicine as whole with a glass of water and do not crush or chew the medicine. Your doctor will decide the right dose depends on your age, body weight and disease condition.

Side Effects Of DART

How To Manage Side Effects

Skin rash Or Itching

Avoid hot showers because hot water can irritate the skin. Do not scratch the affected area. Use sunscreen and protective clothing when outdoors. Regularly use unscented moisturizers to soothe and hydrate the affected area. Contact your doctor if the itching worsens.

Warning & Precautions

Pregnancy

Contraindicated

DART TABLET is generally not recommended for use in pregnancy. Contact your doctor before taking.

Breastfeeding

Contraindicated

DART TABLET is not recommended for use in breastfeeding women as it may pass through the breast milk. Contact your doctor before taking.

Driving and Using Machines

Use with Caution

DART TABLET has no effect on the ability to drive or use machines.

Alcohol

Consult your doctor

Avoid consumption of alcohol while taking DART TABLET. Consult your doctor for advice.

Kidney

Use with Caution

DART TABLET should be used with caution in patients with impaired kidney function. Contact your doctor before taking.

Liver

Use with Caution

DART TABLET should be used with caution in patients with impaired liver function like hepatitis, gilbert’s syndrome. Contact your doctor before taking.

Allergy

Contraindicated

Do not take DART TABLET if you are allergic to Caffeine, Paracetamol, Propyphenazone or any other ingredients of this medicine.

Lungs

Use with Caution

DART TABLET should be used with caution in patients with asthma, chronic rhinitis. Contact your doctor before taking.

Use In Pediatrics

Contraindicated

DART TABLET is not recommended for use in children and adolescents under 12 years of age. Contact your doctor before taking.

Use In Geriatrics

Use with Caution

DART TABLET should be used with caution in elderly patients (aged 65 years or older). Contact your doctor before taking.

Interactions

A. Drug-drug interactions:

Inform your physician if you are taking any of the following medicines:

• Medicines used to manage fits (Ex. phenobarbital, phenytoin, and carbamazepine)
• Rifampicin (a medicine used to manage tuberculosis)
• Propantheline and cimetidine (medicines used to manage ulcers)
• Metoclopramide (medicines used to manage nausea and vomiting)
• Chloramphenicol (a medicine used to manage bacterial infections)
• Zidovudine (a medicine used to manage HIV infection)
• Butabarbital (medicines used to manage insomnia)
• Azelastine (a medicine used to manage allergies)
• Lorazepam (medicines used to manage panic disorders, anxiety, and fits)
• Oral contraceptives (medicines used to avoid pregnancy)
• Disulfiram (a medicine used for alcohol withdrawal)
• Theophylline (a medicine used to manage asthma)
• Ephedrine (a medicine used to manage hypotension)

Overdosage:

If you or anyone else accidentally took too much of this medicine, consult your doctor immediately.

Synopsis

More Information

• Keep out of reach of children
• Store DART TABLET below 25°C

FAQs About DART

Q: What is DART TABLET used for?

A: DART TABLET is a combination of Caffeine, Paracetamol, and Propyphenazone used to manage headaches, body aches, fevers, backache, migraine and dental pain. Contact your doctor before taking the medicine.

Q: Can I consume alcohol while taking DART TABLET?

A: No. Avoid consumption of alcohol while taking DART TABLET. Contact your doctor before taking the medicine.

Q: Can I take DART TABLET if I have asthma?

A: Yes. DART TABLET should be used with caution in patients with asthma. Contact your doctor before taking.

Q: Who should not take DART TABLET?

A: DART TABLET is not recommended for use in patients with allergic to Caffeine, Paracetamol or to Aspirin and Propyphenazone, deficiency of glucose-6-phosphate dehydrogenase or haemolytic anaemia, acute hepatic porphyria, pregnancy, breastfeeding. Contact your doctor before taking the medicine.

Q: Can I take DART TABLET for the long term?

A: No, DART TABLET is not recommended for long-term use as it may cause kidney damage. Contact your doctor before taking.

Q: Can I use DART TABLET for headache?

A: Yes. DART TABLET is used to manage headaches. But do not use more than the recommended duration as advised by your doctor as it may itself lead to adverse effects. Contact your doctor before taking.

Q: Are there any precautions or warnings associated with DART TABLET?

A: Certain medications may have specific precautions or warnings, such as avoiding alcohol, interactions with other drugs, or precautions for certain medical conditions (e.g., pregnancy, liver or kidney problems). It's important to discuss these with your healthcare provider.

Q: What should I do if I miss a dose of DART TABLET?

A: If you miss a dose of DART TABLET, take it as soon as you remember unless it's close to the time for your next dose. In that case, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for a missed dose.

Q: Is DART TABLET available over the counter (OTC) or do I need a prescription?

A: The availability of DART TABLET over the counter or by prescription would depend on its active ingredient(s) and local regulations. Some medications may require a prescription, while others are available OTC.

Q: How should I take DART TABLET?

A: Take DART TABLET as advised by your physician. Swallow this medicine whole with a glass of water, and do not crush or chew the medicine. Your doctor will decide the right dose depending on your age, body weight, and disease condition.

Q: How can I buy DART TABLET online?

A: If you wish to buy DART TABLET on Netmeds, you need a prescription from a registered medical practitioner. Netmeds has made buying online medicines more easy for consumers and is one of India's leading online pharmacies.

References

1. K.D. Tripathi. NSAIDs and Antipyretic-Analgesics & CNS Stimulants and Cognition Enhancers. Essentials of medical pharmacology. Seventh edition. 2013. Page - 206, 488.

2. Bethesda (MD). Caffeine. National Institute of Health. NLM. National Centre for Biotechnology Information. PubChem Compound Summary. 2004. [Accessed on 22nd March 2024] https://pubchem.ncbi.nlm.nih.gov/compound/2519

3. Bethesda (MD). Paracetamol. National Institute of Health. NLM. National Centre for Biotechnology Information. PubChem Compound Summary. 2004. [Accessed on 22nd March 2024] https://pubchem.ncbi.nlm.nih.gov/compound/1983

4. Bethesda (MD). Propyphenazone. National Institute of Health. NLM. National Centre for Biotechnology Information. PubChem Compound Summary. 2004. [Accessed on 22nd March 2024] https://pubchem.ncbi.nlm.nih.gov/compound/3778

5. Mohamed F. Radwan, Kevin N. Dalby, Tamer S. Kaoud. Mechanism of action of Propyphenazone. National Institute of Health. NLM. National Centre for Biotechnology Information. Pubmed.gov. June 2014. [Accessed on 22nd March 2024] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4160749/#:~:text=Propyphenazone%20is%20a%20nonacidic%20pyrazole,with%20minimal%20anti%2Dinflammatory%20activity.&text=The%20coupling%20of%20propyphenazone%20with,prodrugs%20with%20synergistic%20analgesic%20effects.

6. Caffeine + Paracetamol+ Propyphenazone. Mims.com.  [Accessed on 22nd March 2024] https://www.mims.com/philippines/drug/info/saridon%20triple%20action?type=full

7. Saridon (Caffeine + Paracetamol+ Propyphenazone). Bayer Global. [Accessed on 22nd March 2024] https://www.bayer.com/en/id/product/indonesia-pain-medicine-and-allergy

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