Introduction About CORTEYE INJECTION

CORTEYE INJECTION contains Triamcinolone which belongs to the group of medicines called Corticosteroids. It is used to manage pain, swelling and stiffness in joints as seen in various disorders such as Rheumatoid Arthritis. It is also used to manage various allergic disorders such as asthma, hormonal problems, rheumatic fever and various disorders of the digestive system, skin, kidneys and lungs.

CORTEYE INJECTION is not recommended if you are diagnosed with any condition affecting the kidney, liver and thyroid gland or any infection, hypertension and heart failure. Before taking CORTEYE INJECTION, inform your doctor if you have/had infection recently such as Tuberculosis (TB), diabetes, bowel surgery, stomach ulcer and/or a bowel disorder, inflamed veins or infection in legs, mental health disorder, epilepsy, any form of cancer, osteoporosis (thick and brittle bones, myasthenia gravis, glaucoma, have visual disturbances, loss of vision, inflammation of the retina (viral retinitis) or of eyes (red, bloodshot eyes) etc.

CORTEYE INJECTION is not recommended for use in children below 6 years of age. Also, pregnant and nursing women are recommended to inform the doctor about their pregnancy and breastfeeding status, before receiving CORTEYE INJECTION. The most common side effects of taking CORTEYE INJECTION are increased risk of infection, reaction at the site reaction, headache and pain in joints. Consult your doctor if any of your symptoms get worse or persist.

Uses Of CORTEYE INJECTION

• Manage joint pain, swelling and stiffness in various disorders such as rheumatoid arthritis
• Manage various allergic disorders such as asthma
• Manage hormonal problems
• Manage rheumatic fever
• Manage disorders of the digestive system, skin, kidneys and lungs

How CORTEYE INJECTION Works

CORTEYE INJECTION is used to inhibit the synthesis of various chemicals that cause inflammation namely prostaglandins and leukotrienes. It works by decreasing the expression of cyclo-oxygenase, lipoxygenase enzymes, responsible for their production. It also decreases the activity of a certain nuclear factor called kappa-B which leads to decreased production of interleukin 6 and 8, which are pro-inflammatory substances.

How to use CORTEYE INJECTION

CORTEYE INJECTION will be given to you only by a doctor or a nurse in the muscles or joints. Your doctor will decide the correct dose and duration for you depending on your age, body weight and disease condition.

Side Effects Of CORTEYE INJECTION

How To Manage Side Effects

Headache

Stay hydrated and avoid taking products rich in caffeine and avoid harsh lights and loud sounds. Apply a pain-relieving balm on the forehead if needed. Consult your doctor if your symptom gets worse or persist.

Indigestion

Stick to simple meals. Avoid eating heavily rich or spicy food. Stay hydrated. Consult your doctor if it persists or gets worse.

Nausea And Vomiting

Stick to simple meals. Avoid eating heavily rich or spicy food. Drink oral rehydration solution to compensate for the loss of water and minerals. Stay hydrated. Consult your doctor if it persists or gets worse.

Tiredness

Stay hydrated and also maintain an adequate intake of electrolytes throughout the day. Also, take a nutrient-rich diet and healthy calories to sustain energy throughout the day. Consult your doctor if it persists or gets worse.

Visual Disturbances

Keep your spectacles and contact lenses and lens case clean. Also, wash your eyes frequently with water and try to reduce the time spent in front of the screen. Pay a visit to a doctor if the problem worsens or gets prolonged. Consult your doctor if it persists or gets worse.

Weight Gain

Eat healthy and well-balanced meals throughout the day which are packed with healthy and vital nutrients and vitamins. Also, moderate physical exercise is recommended. Consult your doctor if it persists or gets worse.

Warning & Precautions

Pregnancy

Consult your doctor

It is recommended to consult the doctor before receiving CORTEYE INJECTION if you are pregnant or planning pregnancy. 

Breastfeeding

Consult your doctor

It is recommended to consult your doctor before receiving CORTEYE INJECTION, if you are a nursing mother.

Driving and Using Machines

Use with Caution

It is recommended not to drive or use machinery after receiving CORTEYE INJECTION as causes disturbances in vision. Consult your doctor before receiving it.

Kidney

Contraindicated

It is not recommended to receive CORTEYE INJECTION if you have any disorder of kidney. Consult your doctor before receiving it.

Liver

Contraindicated

It is not recommended to receive CORTEYE INJECTION if you have any disorder of liver. Consult before receiving it.

Allergy

Contraindicated

It is not recommended to receive CORTEYE INJECTION if you are allergic to Triamcinolone and/or any other constituent found in CORTEYE INJECTION. Consult your doctor before receiving it.

Heart Disease

Contraindicated

It is not recommended to receive CORTEYE INJECTION if you have increased blood pressure or heart failure. Consulted your doctor before receiving it.

Interactions

A. Drug-Drug Interactions:

Before taking CORTEYE INJECTION, inform your doctor if you are taking any of the following medicine:

• medicines used to manage HIV (Ex. ritonavir, cobicistat)
• medicines used to manage pain and inflammation (Ex. aspirin, ibuprofen)
• medicines used to manage fungal infections (Ex. clarithromycin, ketoconazole etc.)
• medicines used to thin the blood (Ex. warfarin)
• medicines used for contraception or as hormone replacement therapy (HRT) (Ex. estrogen)
• medicines used to manage tuberculosis (rifampicin)
• medicines used to suppress the immune response (Ex. ciclosporin)
• medicines used to manage increased blood pressure and irregular heartbeat (Ex. Digoxin)
• medicines used to manage myasthenia gravis (Ex. pyridostigmine)
• medicines used to manage epilepsy and fits (Ex. phenytoin)
• medicines used to manage diabetes (Ex. insulin, metformin)
• medicines used to manage disorders of the thyroid gland (Ex. levothyroxine, liothyronine)

Overdosage:

CORTEYE INJECTION will be administered to you only by a doctor or a nurse in a hospital, so it is unlikely to receive an overdose. However, consult your doctor or nurse if you experience any unusual symptoms.

Synopsis

More Information

• Keep CORTEYE INJECTION out of reach and sight from children
• Do not store it above the temperature of 25°C

FAQs About CORTEYE INJECTION

Q. Can CORTEYE INJECTION be given to infants?

A. No, CORTEYE INJECTION is not recommended for children below the age of 6. For children above the age of 6 and adults, your doctor will decide the correct dose or select a suitable alternative therapy for your child.

Q. Can I self-administer CORTEYE INJECTION at my home?

A. No, CORTEYE INJECTION is administered only by a doctor or a nurse in the muscles or joints. Do not self-administer it at home. Consult your doctor for advice.

Q. Can I stop receiving CORTEYE INJECTION if I feel better?

A. CORTEYE INJECTION is a steroid medication, Management with steroids should not be abruptly stopped as it may lead to various adverse effects. The dosage of CORTEYE INJECTION is to be gradually reduced.

Q. What are the precautions I should follow during the course of my management with CORTEYE INJECTION?

A. During the course of management with CORTEYE INJECTION, stay away from people who have chickenpox or shingles if you never had it in past as it could have severe effects. Visit a doctor immediately, if you come in contact with a person having it. Also, do not have any vaccinations without your doctor’s consent while receiving CORTEYE INJECTION.

Q. Do I need to follow a special diet while receiving CORTEYE INJECTION?

A. If you are receiving long-term intramuscular management with CORTEYE INJECTION, it is recommended to include more proteins in your diet. It is so because long-term management with steroids can result in gradual loss of weight.

Q. What happens after stopping the CORTEYE INJECTION management?

A. After the termination of your management with CORTEYE INJECTION, there can be the development of certain flu-like symptoms, runny nose or itchy eyes and skin. Usually, after the cessation of management with CORTEYE INJECTION, your doctor may ask you to take oral steroids for a while.

Q. Does CORTEYE INJECTION cause mental illness?

A. Yes, CORTEYE INJECTION is reported to cause mental illness if taken at higher doses. It generally goes away by lowering the dosage. Also, report to a doctor if you feel depressed and have suicidal thoughts.

References

1. KD Tripathi. Corticosteroids. Essentials of medical pharmacology. Seventh edition. 2013. Page – 287-289.

2. Wang, S., Wang, X., Liu, Y., Sun, X. and Tang, Y., 2019. Ultrasound-guided intra-articular triamcinolone acetonide injection for treating refractory small joints arthritis of rheumatoid arthritis patients. [Published on 16th August 2019] [Accessed on 2nd February 2023] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6831351/

3. Bristol-Myers Squibb Pharmaceuticals Unlimited Company. Electronic Medicines Compendium (EMC). [Revised in March 2022] [Accessed on 2nd February 2023] https://www.medicines.org.uk/emc/files/pil.6748.pdf

4. DrugBank. Triamcinolone. [Accessed on 2nd February 2023] https://go.drugbank.com/drugs/DB00620