Introduction About AVAPAR 50 TABLET

AVAPAR 50 TABLET is a combination of Camylofin and Paracetamol which belongs to the group of medicines called Anti-spasmodics, Analgesics and Antipyretics respectively. It is used in the management of abdominal pain and spasm associated with Irritable bowel syndrome (IBS), spasms associated with diarrhea and dysentery, renal colic (pain when the stone gets stuck in the urinary tract causing painful, bloody, or cloudy urination), biliary colic (pain in the abdomen due to obstruction by stones in the bile duct), intestinal colic (cramp-like pain in the small or large intestine) and dysmenorrhea (period or menstrual cramps around the abdomen, hips, lower back).  

Having a fiber-rich diet, keeping yourself hydrated, and quitting smoking and alcohol will help in the management process. Prior to the management, your doctor might want you to take certain blood tests.

Avoid smoking and consumption of alcohol during this management. AVAPAR 50 TABLET is not recommended for use in patients who have narrow-angle glaucoma, prostatic hypertrophy, mechanical stenoses, megacolon, GI hemorrhage, tachyarrhythmia, porphyria, and urinary retention.

Before taking AVAPAR 50 TABLET inform your doctor if you have paralytic ileus, ulcerative colitis, pyloric stenosis, thyrotoxicosis, obstructive lung disease, liver problems, kidney problems, heart problems, fever, and hypertension.

AVAPAR 50 TABLET is not recommended for use in pregnant and breastfeeding women. AVAPAR 50 TABLET is not recommended for use in children and adolescents below 12 years of age.

It should be used with caution above 65 years of age. The most common side effects of taking AVAPAR 50 TABLET are nausea, vomiting, drowsiness, dry mouth, giddiness, dilated pupil, skin rash, and fast heartbeat. Consult your doctor for advice if above side effects do not improve.

Uses Of AVAPAR 50 TABLET

It is used to manage spasms associated with:

• irritable bowel syndrome (IBS)
• diarrhoea and dysentery
• renal colic
• biliary colic
• dysmenorrhoea and pain due to gall stones

How AVAPAR 50 TABLET Works

AVAPAR 50 TABLET works by relieving muscle cramps and pain in which Camylofin is an antispasmodic that relaxes the muscles in the stomach and intestine stopping sudden muscle contractions (spasms), thereby relieving cramps and pain. Paracetamol is an analgesic (pain reliever) and an antipyretic (fever reducer) that works by blocking the release of certain chemical messengers that causes fever and pain.

How to use AVAPAR 50 TABLET

Take AVAPAR 50 TABLET as advised by your physician. Swallow the medicine with water. Do not crush or chew the medicine. Your doctor will decide the right dose and duration depending upon your age, body weight, and disease condition.

Side Effects Of AVAPAR 50 TABLET

How To Manage Side Effects

Nausea or Vomiting:

Take this medicine with meals. Stick to simple meals. Avoid eating rich or spicy food. If the symptom does not show improvement, consult your doctor.

Warning & Precautions

Pregnancy

AVAPAR 50 TABLET is not recommended for use in pregnant women (more than 6 months) or women who are planning to become pregnant. Consult your doctor before taking it.

Breastfeeding

AVAPAR 50 TABLET is not recommended for use in breastfeeding women. Consult your doctor before taking AVAPAR 50 TABLET.

Driving and Using Machines

Do not drive or use machines while taking AVAPAR 50 TABLET as it may cause dizziness, drowsiness, fatigue, and visual disturbances.

Alcohol

Avoid consumption of alcohol while taking AVAPAR 50 TABLET as it can increase the side effect of dizziness.

Kidney

AVAPAR 50 TABLET is not recommended for use in patients with kidney disease. Consult your doctor before taking.

Liver

AVAPAR 50 TABLET is not recommended for use in patients with severe liver disease. Consult your doctor before taking.

Allergy

Do not take AVAPAR 50 TABLET if you are allergic to Camylofin or Paracetamol or any other ingredients of this medicine.

Lungs

AVAPAR 50 TABLET should be used with caution in patients with obstructive airway disease, asthma, and other lung diseases. Consult your doctor before taking.

Heart Disease

AVAPAR 50 TABLET is not recommended for use in patients who had tachyarrhythmia, mechanical stenosis, and other serious heart problems. AVAPAR 50 TABLET should be used with caution in patients with tachycardia, cardiac insufficiency, cardiac surgery, and high blood pressure. Consult your doctor before taking.

Interactions

A. Drug-Drug interactions:

Before taking AVAPAR 50 TABLET, inform your doctor if you are taking any of the following medicine:

• antacids (Ex. aluminium hydroxide, magnesium carbonate)
• anticoagulant (Ex. warfarin, aspirin, clopidogrel, to manage clotting problems)
• antihistamines (Ex. brompheniramine, chlorpheniramine)
• antidepressants (Ex. amitriptyline, paroxetine, imipramine, desipramine, and lithium)
• antipsychotics (Ex. phenothiazines)
• medicine used to manage heart problems (Ex. digoxin), steroids, heart rhythm problems (quinidine), manage high blood pressure (Ex. lisinopril, captopril, atenolol, ramipril, valsartan)
• opioid pain-relief medicine (Ex. pethidine)
• medicines used to manage cholesterol (Ex. statins)
• medicines used to manage gastroesophageal reflux disease (Ex. metochlopramide)
• antiemetics (Ex. domperidone)
• medicine used to manage HIV (Ex. zidovudine)

Overdosage:

If you or anyone else accidentally takes too much of AVAPAR 50 TABLET, consult your doctor immediately or visit the nearby hospital. Symptoms include dry mouth, difficulty in swallowing and talking, flushed and hot skin (especially over face and neck), fever, difficulty in micturition, decreased bowel sounds, dilated pupil, photophobia, blurring of near vision, palpitation, and a scarlet rash may appear.

Synopsis

More Information

• Keep AVAPAR 50 TABLET out of reach of children
• Store at room temperature

FAQs About AVAPAR 50 TABLET

What is AVAPAR 50 TABLET used for?

AVAPAR 50 TABLET is used in the management of abdominal pain and spasm associated with Irritable bowel syndrome (IBS), spasms associated with diarrhea and dysentery, renal colic (pain when the stone gets stuck in the urinary tract causing painful, bloody, or cloudy urination), biliary colic (pain in the abdomen due to obstruction by stones in the bile duct), intestinal colic (cramp-like pain in the small or large intestine) and dysmenorrhea (period or menstrual cramps around the abdomen, hips, lower back). 

Can AVAPAR 50 TABLET be used in patients with kidney problems?

AVAPAR 50 TABLET is not recommended for use in patients with kidney disease. Consult your doctor before taking AVAPAR 50 TABLET.

Can AVAPAR 50 TABLET be used in pregnant women?

AVAPAR 50 TABLET is not recommended for use in pregnant women (more than 6 months) or women who are planning to become pregnant and should be used with caution in the first 6 months of pregnancy. Consult your doctor before taking.

How does AVAPAR 50 TABLET work?

AVAPAR 50 TABLET works by relieving muscle cramps and pain in which Camylofin is an antispasmodic that relaxes the muscles in the stomach and intestine stopping sudden muscle contractions (spasms), thereby relieving cramps and pain. Paracetamol is an analgesic (pain reliever) and an antipyretic (fever reducer) that works by blocking the release of certain chemical messengers that causes fever and pain.

Can AVAPAR 50 TABLET be used in elderly patients?

AVAPAR 50 TABLET should be used with caution in elderly patients above 65 years of age as they are more prone to side effects. The dose will be adjusted by the doctor. Consult your doctor before taking.

References

1. KD Tripathi. Nonsteroidal Anti-inflammatory Drugs and Antipyretic-Analgesics. Essentials of medical pharmacology. Eighth Edition. 2019. Page – 192-209.

2. Nandita Palshetkar, Ameya Purandare, Hemant Mehta, and Rohan Palshetkar. Effectiveness and Safety of Camylofin in Augmentation of Labor: A Systematic Review and Meta-Analysis Journal of Obstetrics and Gynaecology of India. August 2020 [Accessed on 19th July 2022] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7758393/

3. Camylofin. Pubchem. [Accessed on 19th July 2022] https://pubchem.ncbi.nlm.nih.gov/compound/Camylofin

4. CIMS. Camylofin. [Accessed on 19th July 2022] https://www.mims.com/india/drug/info/camylofin?type=full&mtype=generic

5. Paracetamol. NHS. [Revised in May 2022] [Accessed on 19th July 2022] https://www.nhs.uk/medicines/paracetamol-for-adults/

6. Paracetamol. Pubchem. [Accessed on 19th July 2022] https://pubchem.ncbi.nlm.nih.gov/compound/1983#section=Top

7. Paracetamol. ScienceDirect. [Accessed on 19th July 2022] https://www.sciencedirect.com/topics/neuroscience/paracetamol

8. Leeford. Camyfyl Tablet. [Accessed on 19th July 2022] https://www.leeford.in/product/889/camyfyl-tablets

9. Orion Life Science. Camypan Tablet. [Accessed on 19th July 2022] http://www.orionlifeindia.com/camylofin-dihydrochloride-and-paracetamol-tablet-6309654.html

10. Camylofin+ Paracetamol. Medicine India. [Accessed on 19th July 2022] https://www.medicineindia.org/pharmacology-for-generic/287/camylofin-dihydrochloride-paracetamol