Introduction About AVANEXT 200 TABLET

AVANEXT 200 TABLET contains Avanafil, which belongs to the group of medicines called Phosphodiesterase type 5 (PDE 5) inhibitors. It is used in adult men to improve blood flow to the penis.

AVANEXT 200 TABLET is not recommended for use in patients suffering from kidney diseases, heart diseases (history of cardiac arrest, had heart surgery in the past 6 months, uncontrolled blood pressure, chest pain), liver diseases, and eye problems. It is not recommended for use in children or adolescents (less than 18 years of age).

Before taking AVANEXT 200 TABLET, inform your doctor if you are suffering from bleeding disorders, heart troubles, or a physical condition that affects the shape of the penis. The common side effects of taking AVANEXT 200 TABLET may include headache, stuffy nose and flushing. Consult your doctor if any of the symptoms worsen.

Uses Of AVANEXT 200 TABLET

• To improve blood flow to the penis

How AVANEXT 200 TABLET Works

AVANEXT 200 TABLET blocks the phosphodiesterase enzyme in the body and releases a chemical called nitric oxide, which helps to relax the smooth muscles and blood vessels supplying the inner part of the penis. This increases the supply of blood to the penis.

How to use AVANEXT 200 TABLET

Take AVANEXT 200 TABLET exactly as advised by your doctor. Swallow the medicine with a glass of water. It is advised to take AVANEXT 200 TABLET 15 minutes before intercourse to get better results. Your doctor will decide the correct dose and duration for you, depending on your age and the severity of the condition.

Side Effects Of AVANEXT 200 TABLET

How To Manage Side Effects

Dizziness Or Drowsiness

Lie down until the dizziness passes and get up slowly. Do not bend down suddenly. Get a lot of rest. Walk slowly and carefully. Take plenty of fluids. Avoid drinking coffee, alcohol, or smoking. Consult your doctor if the symptom gets worse.

Headache

Drink plenty of fluids and stay hydrated. Avoid consuming alcohol and skipping meals. Try to be relaxed and stress-free. Get adequate sleep and rest. Apply a pain-relieving balm to the forehead if necessary. Consult your doctor if the symptom does not improve.

Stomach Discomfort

Always stay hydrated. Avoid eating oily, fried, or spicy foods. Maintain a well-balanced diet. Do not take alcohol or other carbonated drinks. Consult your doctor if the symptom gets worse.

Tiredness

Drink plenty of fluids and eat a balanced diet with frequent meals. Do regular, minimal exercise, and follow a regular sleep schedule. Consult your doctor if the symptom does not improve.

Warning & Precautions

Pregnancy

Contraindicated

AVANEXT 200 TABLET is not intended for use by women.

Breastfeeding

Contraindicated

AVANEXT 200 TABLET is not intended for use by women.

Driving and Using Machines

Use with Caution

Do not drive or operate any machines if you feel dizzy or have altered vision after taking AVANEXT 200 TABLET.

Alcohol

Consult your doctor

Avoid consuming alcohol while taking AVANEXT 200 TABLET, as there is a chance of developing unwanted symptoms like increased heart rate, a decrease in blood pressure, dizziness, and headache. It may also decrease your ability to get an erection. Consult your doctor for advice.

Kidney

Contraindicated

AVANEXT 200 TABLET is not recommended for use in patients suffering from serious kidney diseases or in patients undergoing dialysis> management. Consult your doctor before taking it.

Liver

Contraindicated

AVANEXT 200 TABLET is not recommended for use in patients suffering from serious liver diseases. Consult your doctor before taking it.

Allergy

Contraindicated

Do not take AVANEXT 200 TABLET if you are allergic to avanafil or any other phosphodiesterase type 5 inhibitor (PDE5) (Ex. Sildenafil).

Heart Disease

Consult your doctor

AVANEXT 200 TABLET is not recommended for use in patients with heart rate disturbances that may cause cardiac arrest (sudden unexpected loss of heart function, consciousness, and breathing), heart attack, chest pain (angina), variation in blood pressure, or if you have had a heart attack in the past 6 months that will disturb your intercourse. AVANEXT 200 TABLET should be used with caution in patients with heart troubles, which may make it risky for them to have sexual intercourse. Consult your doctor before taking it.

Use In Pediatrics

Contraindicated

AVANEXT 200 TABLET is not recommended for use in children and adolescents (less than 18 years of age).

Use In Geriatrics

Consult your doctor

AVANEXT 200 TABLET should be used in elderly patients (aged 65 years and above) after consulting the doctor. Consult your doctor for advice.

Interactions

A. Drug-drug interactions:

Before taking AVANEXT 200 TABLET, inform your doctor if you are taking the following medicines:

• medicines used to manage chest pain (Ex. nitrates like glyceryl trinitrate and isosorbide dinitrate)
• medicines used to manage HIV infections (Ex. ritonavir, indinavir, saquinavir, nelfinavir, amprenavir, or atazanavir)
• medicines to manage fungal infections (Ex. ketoconazole, fluconazole)
• medicines used to manage bacterial infections (Ex. azithromycin, erythromycin, and clarithromycin)
• medicines used to manage high blood pressure (Ex. terazosin, doxazosin, verapamil)
• medicines used to manage an irregular heartbeat (Ex. quinidine, procainamide, amiodarone, or sotalol)
• medicines used to manage fits (Ex. carbamazepine, phenobarbital, or primidone)
• aprepitant (used to manage nausea caused by chemotherapy)
• riociguat (used to manage pulmonary hypertension)

B. Drug-food interactions:

Avoid drinking grapefruit juice within 24 hours prior to taking AVANEXT 200 TABLET, as it may increase the risk of side effects.

Overdosage:

If you or anyone else accidentally takes too much of AVANEXT 200 TABLET, consult your doctor immediately or visit the nearby hospital.

Synopsis

More Information

• Keep AVANEXT 200 TABLET out of reach of children
• Store it at room temperature

FAQs About AVANEXT 200 TABLET

Q: What is AVANEXT 200 TABLET used for?

A: AVANEXT 200 TABLET is used in adult men to help improve blood flow to the male reproductive organ. Consult your doctor before taking it.

Q: Can I consume alcohol while taking AVANEXT 200 TABLET?

A: Do not drink alcohol while taking AVANEXT 200 TABLET, as there is a chance of developing unwanted symptoms like increased heart rate, a decrease in blood pressure, dizziness, and headache. Consult your doctor for advice before taking AVANEXT 200 TABLET.

Q: What are the common side effects of AVANEXT 200 TABLET?

A: The most common side effects of taking AVANEXT 200 TABLET are headaches, stuffy noses, and flushing. Consult your doctor before taking AVANEXT 200 TABLET.

Q: Is AVANEXT 200 TABLET safe to use in patients with heart problems?

A: AVANEXT 200 TABLET is not recommended for use in patients with heart rate disturbances that may cause cardiac arrest (sudden unexpected loss of heart function, consciousness, and breathing), heart attack, chest pain (angina), variation in blood pressure, or if you have had a heart attack in the past 6 months that will disturb your intercourse. AVANEXT 200 TABLET should be used with caution in patients with heart troubles. Consult your doctor before taking it.

Q: How does AVANEXT 200 TABLET work?

A: AVANEXT 200 TABLET works by blocking the phosphodiesterase enzyme in the body and releasing a chemical called nitric oxide, which helps to relax the smooth muscles and blood vessels supplying the inner part of the penis. This increases the supply of blood to penis.

Q: Can I take AVANEXT 200 TABLET with other medications?

A:It is important to inform your doctor about all medications you are currently taking, including prescription medications, over-the-counter drugs, and herbal supplements. AVANEXT 200 TABLET should not be taken with nitrates or alpha-blockers, as this can lead to a dangerous drop in blood pressure.

Q: Who should not take AVANEXT 200 TABLET?

A: AVANEXT 200 TABLET is not suitable for everyone. Men with certain medical conditions such as severe heart or liver problems, uncontrolled high or low blood pressure, or a history of stroke should not take AVANEXT 200 TABLET. Additionally, individuals who are allergic to Avanafil or any of its ingredients should avoid using this medication.

Q: Is AVANEXT 200 TABLET available over the counter?

A: No, AVANEXT 200 TABLET is a prescription medication and is not available over the counter. It should be used only under the supervision of a healthcare provider.

Q: Can AVANEXT 200 TABLET be used by patients with diabetes?

A: AVANEXT 200 TABLET can be used by individuals with diabetes, but it is important to discuss any underlying medical conditions with a healthcare provider before starting management.

Q: Is AVANEXT 200 TABLET effective for men who have had prostate surgery?

A: If the medicine needed for men who have had a prostatectomy or other prostate surgery. Your doctor will prescribe AVANEXT 200 TABLET according to their age, body weight and disease condition.

References

1. KD Tripathi. Autocoids and related drugs. Essentials of Medical Pharmacology. Eighth edition. 2019. Page – 327-328.

2. Jeffery A. Kyle, Dana A. Brown and Jerame K. Hill. Avanafil for erectile dysfunction. Annals of Pharmacotherapy. Sage journals. September 2013. [Accessed on 30th July 2022] https://journals.sagepub.com/doi/abs/10.1177/1060028013501989

3. Vivus LLC. Long-Term Safety and Efficacy Study of Avanafil in Men With Erectile Dysfunction. NIH U.S. National Library of Medicine ClinicalTrials.gov. [Revised in August 2012] [Accessed on 30th July 2022] https://clinicaltrials.gov/ct2/show/NCT00853606

4. Menarini - Von Heyden GmbH. Electronic Medicines Compendium (EMC) [Revised in November 2021] [Accessed on 30th July 2022] https://www.medicines.org.uk/emc/files/pil.5331.pdf

5. Menarini Australia Pty Ltd. Spedra (Avanafil). October 2016. [Accessed on 30th July 2022] https://www.tga.gov.au/sites/default/files/auspar-avanafil-161027-pi.pdf

6. Cipla Ltd. Avanair Tablets (Avanafil) Ciplamed. [Revised in March 2022] [Accessed on 30th July 2022] https://www.ciplamed.com/content/avanair-tablets

7. Mist Pharmaceuticals, LLC. NIH. National Library of Medicine. Stendra-Avanafil tablet. Dailymed. [Revised in May 2021] [Accessed on 30th July 2022] https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=a8726f90-9329-46ca-9379-2b50c78fe0e2

Useful Diagnostic Tests

• Kidney Function Tests
• Liver Function Tests
• Electrocardiogram (ECG)