Uses of Chlorthalidone+Losartan

The combination of Chlorthalidone and Losartan is used in adults to treat mild to moderate high blood pressure which is not adequately controlled by monotherapy. 

Therapeutic Category

Chlorthalidone: Antihypertensive agents (Thiazide-like diuretics)

Losartan: Antihypertensive agents (Angiotensin receptor blockers (ARBs))

How Chlorthalidone+Losartan works

Chlorthalidone + Losartan effectively reduces elevated blood pressure where losartan acts by blocking the actions of Angiotensin – II (a substance that causes narrowing of blood vessels and increase in blood pressure) at the angiotensin type-I receptors of the vascular smooth muscle and chlorthalidone acts by increasing the urinary excretion of sodium and water by inhibiting sodium-chloride reabsorption in the kidneys, thus leading to a marked decrease in blood pressure. 

Common side effects of Chlorthalidone+Losartan

• nettle rash, skin rash
• low blood pressure
• dizziness
• loss of appetite, upset stomach
• impotence in men 

When to consult your doctor

Consult your doctor:

• In case of accidental overdosage
• If you experience severe allergic reaction (signs include rash, itching, swelling of the face, lips, mouth or throat that may cause trouble swallowing or breathing)
• If you experience muscle weakness or abnormal heartbeat

Health Tips for Chlorthalidone+Losartan

• Reduce your intake of high-sodium items including processed foods, fast food and salty snacks. Lowering sodium intake can help reduce blood pressure. Cut back on processed and high-sugar foods, as they can contribute to weight gain and high blood pressure
• Stay hydrated by drinking plenty of water throughout the day. Proper hydration is essential for overall health and blood pressure control
• Exercise on a regular basis can help decrease blood pressure and enhance cardiovascular health. As prescribed by your doctor, aim for at least 150 minutes of moderate-intensity aerobic activity every week
• If you are overweight, decreasing weight can improve your blood pressure control substantially. A healthy weight improves general well-being
• Avoid drinking alcohol as it can affect the blood pressure and interact with your medications
• Use stress-relieving strategies such as meditation and deep breathing exercises. Stress reduction can improve blood pressure levels
• Monitor your blood pressure on a regular basis, as directed by your doctor. Keeping track of your blood pressure levels assists you and your doctor in determining the efficacy of the treatment
• Take Chlorthalidone + Losartan exactly as directed by your doctor. Follow the specified dosage and regimen. Do not change the dosage or discontinue the medicine without first consulting your doctor