Introduction About ZORBAX 125 SUSPENSION

ZORBAX 125 SUSPENSION contains Griseofulvin, which belongs to the group of medicines called Anti-fungals. It is used to manage fungal infections of the skin, hair or nails where topical therapy is not suitable or has failed to manage the condition.

Avoid consumption of alcohol during management with ZORBAX 125 SUSPENSION, as it may cause nausea, vomiting or flushing. Before taking ZORBAX 125 SUSPENSION, inform your doctor if you have skin, liver or kidney problems or porphyria (which results from an increase in certain chemicals related to red blood cell proteins).

ZORBAX 125 SUSPENSION is not recommended for pregnant women. It is not known if this medicine passes into breast milk in breastfeeding women; therefore, consult your doctor before taking it. The most common side effects of taking ZORBAX 125 SUSPENSION are skin conditions like rashes. Contact your doctor if any of the symptoms worsen.

Uses Of ZORBAX 125 SUSPENSION

• Manage fungal infections (ringworm) of skin, hair and nails

How ZORBAX 125 SUSPENSION Works

ZORBAX 125 SUSPENSION inhibits the growth of fungi by binding to a part of the fungus causing the infection in the body. This stops the fungus from multiplying. It also manages fungus from spreading to new cells. These actions cause the fungal infection to shed completely.

How to use ZORBAX 125 SUSPENSION

Take ZORBAX 125 SUSPENSION as advised by your physician. Shake well before use. Your doctor will decide the correct dose and duration for you depending on your age, body weight and disease condition.

Side Effects Of ZORBAX 125 SUSPENSION

Warning & Precautions

Pregnancy

ZORBAX 125 SUSPENSION is not recommended for use in pregnant women or women who may become pregnant during> management. Consult your doctor before taking it.

Breastfeeding

It is unknown if ZORBAX 125 SUSPENSION passes into breast milk. Consult your doctor before taking it.

Alcohol

Avoid consumption of alcohol while taking ZORBAX 125 SUSPENSION as it may cause nausea, vomiting, flushing, hast heartbeat or low blood pressure.

Kidney

Periodic monitoring of kidney functions is required in patients taking ZORBAX 125 SUSPENSION.

Liver

ZORBAX 125 SUSPENSION is not recommended in patients with liver failure. Periodic monitoring of liver functions is required. Consult your doctor before taking it.

Allergy

Do not take ZORBAX 125 SUSPENSION if you are allergic to Griseofulvin.

Interactions

A. Drug-Drug interactions:

Before taking ZORBAX 125 SUSPENSION, inform your doctor if you are taking any of the following medicine:

• medicines used to thin your blood (Ex. warfarin, clopidogrel)
• oral contraceptives (used to manage pregnancy) Ex. ethinyl estradiol, norethindrone
• ciclosporin (used after organ transplantation to manage organ rejection)
• salicylates (used to manage pain, fever or inflammation) Ex. aspirin
• barbiturates (used to manage fits or to induce sleep) Ex. phenobarbital, primidone
• medicines used to manage infections (Ex. penicillin)

Overdosage:

If you or anyone else accidentally take too much of ZORBAX 125 SUSPENSION, consult your doctor immediately or visit the nearby hospital.

Synopsis

More Information

• Keep ZORBAX 125 SUSPENSION out of reach from children
• Do not store above 25°C

FAQs About ZORBAX 125 SUSPENSION

What is the use of ZORBAX 125 SUSPENSION?

ZORBAX 125 SUSPENSION is an antifungal medicine that is used to manage certain kinds of fungal or yeast infections of the skin, hair or nails that are not effectively managed by other topical managements. The medicine works by inhibiting the growth of fungus.

Is ZORBAX 125 SUSPENSION safe for a child?

ZORBAX 125 SUSPENSION can be used in children over 2 years of age, depending on the body weight, age and condition of the disease. Therefore, consult your doctor before taking the medicine.

How fast does ZORBAX 125 SUSPENSION work?

ZORBAX 125 SUSPENSION usually takes about two to four weeks to show improvement in the symptoms of skin infections and about four to six weeks for hair and scalp infections to be completely gone. Take the medicine for as long as advised by your doctor for effective management of the infection.

Can ZORBAX 125 SUSPENSION cause liver damage?

Yes, ZORBAX 125 SUSPENSION may cause yellowish discoloration of the skin or eyeballs along with abdominal pain, fatigue and fever, along with elevated levels of liver enzymes in laboratory tests. These reactions may be serious and result in hospitalisation or death. Hence, patients should be monitored for liver function while taking ZORBAX 125 SUSPENSION for the long term.

Can ZORBAX 125 SUSPENSION cause diarrhea?

Yes. Diarrhea is occasionally reported in patients taking ZORBAX 125 SUSPENSION. Drink lots of fluids, such as water or fruit juice, to keep yourself hydrated. Do not consume any medicine on your own without consulting your doctor. If you experience persistent diarrhea, consult your doctor.

Can ZORBAX 125 SUSPENSION be used during pregnancy?

ZORBAX 125 SUSPENSION is not recommended for use during pregnancy as it may harm your baby. So, inform your doctor if you are pregnant, think you are pregnant or plan to get pregnant before taking it.

Can ZORBAX 125 SUSPENSION cause rashes?

Yes. Skin problems like rashes and hives are common symptoms of ZORBAX 125 SUSPENSION. Do not consume any medicine on your own without asking your doctor. Inform your doctor immediately if you feel like they’re getting worse.

Can I stop taking ZORBAX 125 SUSPENSION?

ZORBAX 125 SUSPENSION should be taken as advised by the physician to work properly. You must continue taking it until the infecting organism is completely eradicated, as indicated by an appropriate examination. If you stop early, the infection may recur.

What if I forget to take a dose of ZORBAX 125 SUSPENSION?

If you forget to take a dose of ZORBAX 125 SUSPENSION, take it as soon as you remember and then continue your management as usual. Do not take the medicine twice to make up for the forgotten dose.

Can ZORBAX 125 SUSPENSION make my skin sun-sensitive?

Yes. Your skin becomes more sensitive to sunlight or ultraviolet (UV) light when taking ZORBAX 125 SUSPENSION. Avoid going to places with strong sunlight or artificial UV light such as sunbeds. In case of while going out protect your skin by applying sunscreen protection cream with the approval of your doctor which helps to manage sunburn allergy reactions. Inform your doctor if you have a previous history of skin problems before taking ZORBAX 125 SUSPENSION.

References

1. KD Tripathi. Antifungal Drugs. Essentials of medical pharmacology. Seventh edition. 2013. Page – 790-791.

2. Jazmine M. Olson; Todd Troxell. Griseofulvin. NCBI; PMC. National Library of Medicine, National Institute of Health. [Revised in April 2022]. [Accessed on 2nd May 2022] https://www.ncbi.nlm.nih.gov/books/NBK537323/

3. Ronald M. Reisner, Richard S. Homer, Victor D. Newcomer, and Thomas H. Sternberg. Onychomycosis of the feet—Treatment with Griseofulvin. NIH. National Library of Medicine. NCBI. PMC. Pubmed Central [Revised in October 1960] [Accessed on 2nd May 2022]  https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1578431/

4. Janssen Pharmaceuticals, Inc. U.S. Food & Drug Administration. [Revised in September 2011] [Accessed on 2nd May 2022] https://www.accessdata.fda.gov/drugsatfda_docs/label/2014/062279s022lbl.pdf

5. Griseofulvin. Drugbank. [Accessed on 2nd May 2022] https://go.drugbank.com/drugs/DB00400

6. Griseofulvin- microsize suspension. Dailymed. [Accessed on 2nd May 2022] https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=9f7e4ecf-f992-42c5-81ea-91e6587b22a5&audience=consumer