Introduction About X DERM PLUS CREAM

X DERM PLUS CREAM is used to provide relief from skin infection, inflammation, itching, irritation, redness and swelling. It contains a combination of Beclomethasone, Clotrimazole and Neomycin.

Beclomethasone is a steroid medicine. It works by making your body not release certain chemicals that causes inflammation and swelling. Clotrimazole and neomycin stops the activity of microbes (fungi and bacteria) which when applied at the infected site.

X DERM PLUS CREAM is strictly for external use only. Apply a thin layer of X DERM PLUS CREAM on the affected skin areas. Avoid its contact with your eyes, mouth, ears, nose, or any open wounds. Do not use X DERM PLUS CREAM for more than 4 weeks without consulting your doctor.

Before using X DERM PLUS CREAM inform your doctor if you have any viral skin infections, skin ulcers, spotty red rash around the mouth, acne, rosacea (redness of skin) or itching of your anus (back passage) or genital areas as a precaution. Consult your doctor before using X DERM PLUS CREAM if you are pregnant or breastfeeding.

The most common side effects of applying X DERM PLUS CREAM are skin thinning and application site irritation and burning sensation. Consult your doctor if this side effect trouble you.

Uses Of X DERM PLUS CREAM

• Skin infections (Fungal and Bacterial origin)
• Skin inflammation, itching, irritation, redness and swelling associated with autoimmune skin conditions

How X DERM PLUS CREAM Works

X DERM PLUS CREAM contains three medicines, namely beclomethasone, clotrimazole and neomycin. Beclomethasone is a steroid medicine which stops your body from producing certain chemicals that causes inflammation and swelling, while parallelly making your body release chemicals that heals inflammation.

Clotrimazole is an antifungal medication which works by inhibiting the synthesis of ergosterol, an essential component of fungal cell membranes. Without ergosterol, the cell membranes become weakened and leaky, leading to fungal cell damage.

Neomycin is an antibiotic which stops protein synthesis in bacteria which is necessary for it to survive. As a result, it disrupts bacterial growth and replication and controls the spread of bacterial infection.

How to use X DERM PLUS CREAM

Apply a small amount of X DERM PLUS CREAM into the affected skin areas or directed by the physician. It is for topical use only. Wash your hands before and after application.

Your doctor will decide the correct dose and duration of therapy for you depending upon your age, body weight and health condition. Do not stop using or overuse X DERM PLUS CREAM without consulting your doctor.

Avoid contact of X DERM PLUS CREAM with your eyes, mouth, ears, nose or with open wounds. In case of accidental contact, rinse with plenty of water.

Side Effects Of X DERM PLUS CREAM

How To Manage Side Effects

Application Site Reactions

Gently cleanse the irritated area with mild, fragrance-free soap and lukewarm water to remove any irritants or debris. Avoid using hot water, harsh soaps, or scrubbing vigorously, as these can further irritate the skin. After cleansing, gently pat the skin dry with a soft towel, avoiding rubbing. Next, apply a soothing moisturizer or emollient cream to help hydrate and protect the skin barrier. Look for products containing ingredients like aloe vera, oatmeal, or ceramides, which have calming and moisturizing properties. Additionally, consider avoiding known triggers or irritants that may exacerbate the skin irritation, such as harsh chemicals, fragrances, or rough fabrics. Opt for loose-fitting, breathable clothing made from natural fibers like cotton to minimize further irritation. If the skin irritation persists, worsens, or is accompanied by other concerning symptoms like severe pain, swelling, or signs of infection, it's essential to seek medical advice from a doctor.

Warning & Precautions

Pregnancy

Consult your doctor

There is inadequate information regarding the safety of X DERM PLUS CREAM during pregnancy.  Hence, X DERM PLUS CREAM should be used in pregnant women only if it is considered necessary by the doctor. Therefore, consult your doctor before using it.

Breastfeeding

Consult your doctor

X DERM PLUS CREAM can be used in breastfeeding women if required. However, consult your doctor before using it.

Driving and Using Machines

Safe

X DERM PLUS CREAM is unlikely to affect your ability to drive or use machines.

Allergy

Contraindicated

Do not use X DERM PLUS CREAM if you are allergic to beclomethasone, clotrimazole or neomycin.

Use In Pediatrics

Consult your doctor

X DERM PLUS CREAM should be used in children and adolescents (aged 12 year or older) only if prescribed by the physician. There is no proper study information regarding the use of X DERM PLUS CREAM in children aged below 12 years. Therefore, consult your doctor before using it.

Use In Geriatrics

Use with Caution

X DERM PLUS CREAM should be used with caution in elderly patients. Therefore, consult your doctor before using it.

Interactions

A. Drug - Drug interactions

Before using X DERM PLUS CREAM, inform your doctor if you are using any of the following medicines including prescription, non-prescription and/or herbal supplements.

Overdosage

X DERM PLUS CREAM is for external use only. Therefore, it is unlikely to cause any overdosage. However, if you applied too much of this medicine, rinse with water. Alternatively, if you or anyone else accidentally swallowed X DERM PLUS CREAM, consult your doctor for advice or visit the nearby hospital.

Synopsis

More Information

FAQs About X DERM PLUS CREAM

Q: What is X DERM PLUS CREAM used for?

A: X DERM PLUS CREAM is used to provide relief from skin infection, inflammation, itching, irritation, redness and swelling associated with certain skin problems, such as psoriasis and eczema (atopic dermatitis).

Q: How X DERM PLUS CREAM works?

A: X DERM PLUS CREAM contains a combination of Beclomethasone, Clotrimazole and Neomycin. Beclomethasone is a steroid medicine. It works by making your body not release certain chemicals that causes inflammation and swelling. Clotrimazole and neomycin stops the activity of microbes (fungi and bacteria) which when applied at the infected site. Together, they provide relief from skin infection, irritation and inflammation.

Q: How to use X DERM PLUS CREAM?

A: Apply a small amount of X DERM PLUS CREAM into the affected skin areas or directed by the physician. It is for topical use only. Wash your hands before and after application.

Q: What precautions must be followed while using X DERM PLUS CREAM?

A: X DERM PLUS CREAM is for topical use only. Avoid contact of X DERM PLUS CREAM with your eyes, mouth, ears, nose or with open wounds. Wash your hands before and after application. Before using X DERM PLUS CREAM inform your doctor if you have acne, or any viral skin infections or skin ulcers or sores. Consult your doctor before using X DERM PLUS CREAM if you are pregnant or breastfeeding.

Q: Is X DERM PLUS CREAM safe?

A: X DERM PLUS CREAM is safe at doses prescribed by the physician. When in some individuals it may cause skin irritation and discomfort. Consult your doctor if this bothers you.

Q: What are the common side effects of using X DERM PLUS CREAM?

A: The most common side effects of applying X DERM PLUS CREAM are skin thinning and application site irritation or burning sensation. Consult your doctor if this side effect trouble you.

Q: How long will it take for X DERM PLUS CREAM to heal my condition?

A: It may around take 2-4 weeks for you to heal. However, you might see an improvement in your condition within the first week of the therapy. The recovery period may differ from person to person based on severity of skin condition.

Q: Can I use other topical medicines while using X DERM PLUS CREAM?

A: Avoid using any other topical medicines along with X DERM PLUS CREAM without consulting your doctor.

Q: Can X DERM PLUS CREAM be used in children?

A: X DERM PLUS CREAM should be used in children and adolescents (aged 12 year or older) only if prescribed by the physician. There is no proper study information regarding the use of X DERM PLUS CREAM in children aged below 12 years. Therefore, consult your doctor before using it.

Q: Can X DERM PLUS CREAM be used in pregnancy?

A: There is inadequate information regarding the safety of X DERM PLUS CREAM during pregnancy. Hence, X DERM PLUS CREAM should be used in pregnant women only if it is considered necessary by the doctor. Therefore, consult your doctor before using it.

Q: Can I use X DERM PLUS CREAM for psoriasis?

A: Yes. X DERM PLUS CREAM is used to reduce the redness and itchiness associated with certain skin problems, such as psoriasis and eczema (atopic dermatitis).

Q: Can I discontinue X DERM PLUS CREAM once my symptoms improve?

A: No, it's important not to discontinue X DERM PLUS CREAM and to finish the entire course of therapy, even if you start feeling better. Improvement in symptoms may occur before the skin infection is fully managed.

References

1. KD. Tripathi. Essential of Medical Pharmacology. 7th Edition. Antifungal agents. Aminoglycoside Antibiotics. Drugs Acting on Skin and Mucous Membrane. Page – 743, 750, 787, 792, & 895.
2. Leeford Healthcare Ltd. Diprolite Cream 15gm. [Accessed on 9th May 2024]. https://www.leeford.in/product/1260/diprolite
3. HAB PHARMACEUTICL & RESEARCH LTD. TURBODERM (Clotrimazole, Beclomethasone Dipropionate, Neomycin Sulfate Cream). NAFDAC.Gov.ng. [Accessed on 9th May 2024]. https://www.nafdac.gov.ng/wp-content/uploads/Files/SMPC/November_2022_Revised/TURBODERM-CREAM.pdf
4. Purna Pharmaceuticals NV. Electronic Medicines Compendium (EMC). [Revised in September 2021] [Accessed on 9th May 2024]. https://www.medicines.org.uk/emc/files/pil.12941.pdf
5. Beclomethasone for skin. NHS. UK. [Accessed on 9th May 2024]. https://www.nhs.uk/medicines/beclometasone-skin-creams/#:~:text=Beclometasone%20skin%20creams%20are%20available,same%20as%20an%20anabolic%20steroid.
6. Neomycin Topical. MedlinePlus. American Society of Health System Pharmacists. [Revised in June 2017]. [Accessed on 9th May 2024]. https://medlineplus.gov/druginfo/meds/a682274.html
7. Clotrimazole Cream 1%. Viatris UK Healthcare Limited. [July 2022]. [Accessed on 9th May 2024]. https://www.medicines.org.uk/emc/files/pil.2598.pdf

Useful Diagnostic Tests

• Complete Blood Count
• Skin Care Package