Introduction About WIKORYL SUSPENSION

Wikoryl Oral Suspension American Ice cream Flavour is a combination of Chlorpheniramine, Paracetamol, and Phenylephrine, which belong to the group of medicines called Antihistamines, Analgesics, and Nasal decongestants, respectively. It is used to relieve the symptoms of allergic rhinitis (hay fever), common cold, and other upper respiratory allergies, like headache, facial congestion and pressure, nasal congestion, runny nose, sneezing, minor aches and pains, itchy nose, throat, eyes, and watery eyes.

It can also be used as an adjunct with antibiotics in sinusitis (inflammation of cavities around your nose), tonsillitis (inflammation of tonsils), and otitis media (inflammation inside the middle ear). Hay fever is a seasonal allergy that occurs in response to specific allergens like pollens, present at certain times of the year (spring or fall) and causes more short-term symptoms.

Wikoryl Oral Suspension American Ice cream Flavour is not recommended for use in children (aged less than 2 months). Consult your doctor for advice. Before taking Wikoryl Oral Suspension American Ice cream Flavour, inform your doctor if you have any kidney, liver, heart, thyroid, or lung problems, diabetes, or glaucoma. Consult your doctor for advice. Wikoryl Oral Suspension American Ice cream Flavour should be used with caution by pregnant and breastfeeding women, consult your doctor before taking the medicine.

The most common side effects of taking Wikoryl Oral Suspension American Ice cream Flavour are vomiting, nausea, allergic reactions, sleepiness, and headaches. Contact your doctor if any of the above side effects worsen.

Uses Of WIKORYL SUSPENSION

It is used:

• to relieve the symptoms of allergic rhinitis, common cold, or other upper respiratory allergies
• as an adjunct with antibiotics in sinusitis, tonsillitis, and otitis media

How WIKORYL SUSPENSION Works

Wikoryl Oral Suspension American Ice cream Flavour relieves upper respiratory symptoms where Chlorpheniramine binds to the histamine H1 receptor and blocks its action, resulting in temporary relief of the negative symptoms (runny nose, sneezing, watery eyes) brought on by histamine. Paracetamol relieves pain by elevating the pain threshold and reduces fever by acting on the heat-regulating center in brain. Phenylephrine constricts blood vessels and reduces the blood flow to certain areas, thus decreasing swelling and allowing nasal and respiratory passages to open up.

How to use WIKORYL SUSPENSION

Take Wikoryl Oral Suspension American Ice cream Flavour as advised by your physician. Shake well before use. Your doctor will decide the correct dose and duration for you depending on your age, body weight, and disease condition.

Side Effects Of WIKORYL SUSPENSION

How To Manage Side Effects

Dizziness Or Drowsiness

Lie down until dizziness is gone, then get up slowly. Move slowly and carefully, do not hurry. Get adequate rest. Drink plenty of water and other fluids. Avoid coffee, cigarettes and alcohol.

Headache

Drink ample amount of water. Get adequate rest. Try to be relaxed and stress free. Ask your doctor before taking any medicine for headache.

Nausea And Vomiting

Take regular sips of a cold drink. Have ginger or peppermint tea. Stick to simple meals. Avoid eating oily or spicy foods. Get adequate rest. Drink lots of fluids, especially water. Do not take any medicine without asking your doctor.

Warning & Precautions

Pregnancy

Monitoring required

Wikoryl Oral Suspension American Ice cream Flavour should be used in pregnant women only if considered clearly necessary by your doctor. Consult your doctor before taking it.

Breastfeeding

Monitoring required

Wikoryl Oral Suspension American Ice cream Flavour should be used in breastfeeding women only if considered clearly necessary by your doctor. Consult your doctor before taking it.

Driving and Using Machines

Use with Caution

Do not drive or use any machines during management with Wikoryl Oral Suspension American Ice cream Flavour. Consult your doctor for advice.

Alcohol

Consult your doctor

Avoid consumption of alcohol with Wikoryl Oral Suspension American Ice cream Flavour. It should be used with caution in patients with alcohol dependence. Consult your doctor before taking Wikoryl Oral Suspension American Ice cream Flavour.

Kidney

Use with Caution

Wikoryl Oral Suspension American Ice cream Flavour should be used with caution in patients with kidney dysfunction and urinary retention. Consult your doctor before taking the medicine.

Liver

Consult your doctor

Wikoryl Oral Suspension American Ice cream Flavour is not recommended for use in patients with liver insufficiency, failure, or active liver disease. Wikoryl Oral Suspension American Ice cream Flavour should be used with caution in patients with liver dysfunction. Consult your doctor before taking the medicine.

Allergy

Contraindicated

Do not take Wikoryl Oral Suspension American Ice cream Flavour if you are allergic to Chlorpheniramine, Paracetamol, Phenylephrine, or any other ingredients in this medicine.

Lungs

Use with Caution

Wikoryl Oral Suspension American Ice cream Flavour should be used with caution in patients with chronic bronchitis, asthma, bronchiectasis, and coughs that last a long time or that occur with too much phlegm. Consult your doctor before taking it.

Heart Disease

Contraindicated

Wikoryl Oral Suspension American Ice cream Flavour is not recommended in patients with severely high blood pressure or any other cardiovascular problems. Consult your doctor before taking it.

Use In Pediatrics

Contraindicated

Wikoryl Oral Suspension American Ice cream Flavour is not recommended for use in children (aged less than 2 years). Your doctor will prescribe the right dose depending on your child’s age, body weight, and disease condition. Consult your doctor before taking it.

Use In Geriatrics

Use with Caution

Wikoryl Oral Suspension American Ice cream Flavour should be used with caution in elderly patients, as they may be at a greater risk of getting side effects. Consult your doctor before taking it.

Interactions

A. Drug-Drug interactions:

Before taking Wikoryl Oral Suspension American Ice cream Flavour, inform your doctor if you are taking any of the following medicines:

• medicines used to manage depression (Ex. isocarboxazid, phenelzine, tranylcypromine)
• cholestyramine (used to lower blood cholesterol levels)
• medicines used to manage nausea and vomiting (Ex. metoclopramide, domperidone)
• medicines used to induce sleep or manage anxiety (Ex. zolpidem, diazepam, and alprazolam)
• warfarin (used to manage blood clot)
• medicines used for high blood pressure (reserpine, veratrum alkaloids, methyldopa, mecamylamines)
• medicines used to relax muscles (Ex. salbutamol, terbutaline)

Overdosage:

If you or anyone else accidentally took too much of Wikoryl Oral Suspension American Ice cream Flavour, contact your doctor immediately or visit a nearby hospital.

Synopsis

More Information

• Keep Wikoryl Oral Suspension American Ice cream Flavour out of reach of children
• Store below 30°C

FAQs About WIKORYL SUSPENSION

Q: Can WIKORYL SUSPENSION be used on infants?

A: WIKORYL SUSPENSION is not recommended for use in children (aged less than 2 years). Your doctor will prescribe the right dose depending on your child’s age, body weight, and disease condition. Consult your doctor before taking it.

Q: What if I forget to take a dose of WIKORYL SUSPENSION?

A: If you forget to take a dose of WIKORYL SUSPENSION, take it as soon as you remember. However, omit the missed dose if it is almost time for the next dose. Do not take the medicine twice to make up for a forgotten dose.

Q: How does WIKORYL SUSPENSION work?

A: WIKORYL SUSPENSION relieves upper respiratory symptoms where chlorpheniramine binds to the histamine H1 receptor and blocks its action, resulting in temporary relief of the negative symptoms (runny nose, sneezing, watery eyes) brought on by histamine. Paracetamol relieves pain by elevating the pain threshold, and it reduces fever by acting on the heat-regulating center in your brain. Phenylephrine constricts blood vessels and reduces the blood flow to certain areas, thus decreasing swelling and allowing nasal and respiratory passages to open up.

Q: What is the use of WIKORYL SUSPENSION?

A: WIKORYL SUSPENSION is used to relieve the symptoms of hay fever, common cold, or other upper respiratory allergies, like headache, facial congestion and pressure, nasal congestion, runny nose, sneezing, minor aches and pains, itching of the nose, throat, or eyes, and watery eyes. It can also be used to clear nasal passages and decongest facial openings and passages.

Q: Can I drink alcohol while taking WIKORYL SUSPENSION?

A: No, avoid consumption of alcohol with WIKORYL SUSPENSION, as it may affect you more than usual. WIKORYL SUSPENSION should be used with caution in patients with alcohol dependence.

Q: Can WIKORYL SUSPENSION cause nausea?

A: Yes. WIKORYL SUSPENSION causes nausea. Take WIKORYL SUSPENSION with or just after a meal or a snack, stick to simple meals, and do not eat oil-rich, fried, or spicy food. Consult your doctor if the symptom does not improve.

Q: Can I stop taking WIKORYL SUSPENSION?

A: Do not stop taking WIKORYL SUSPENSION without consulting your doctor. You can do it if you experience any serious side effects from your doctor’s consultation. If you have any more doubts regarding the use of WIKORYL SUSPENSION, ask your doctor.

Q: Can WIKORYL SUSPENSION cause dizziness?

A: Dizziness is a common side effect of WIKORYL SUSPENSION. In such a case, lie down until the dizziness is gone, then get up slowly. Move slowly and carefully, do not hurry. Get adequate rest. Drink plenty of water and other fluids. Avoid coffee, cigarettes, and alcohol, and tell your doctor if your dizziness does not improve.

Q: Can WIKORYL SUSPENSION be taken during pregnancy?

A: WIKORYL SUSPENSION should be used in pregnancy only if considered clearly necessary by your doctor. If you are pregnant, think you may be pregnant, or are planning to get pregnant, consult your doctor before taking this medicine.

Q: What precautions must be taken while using WIKORYL SUSPENSION?

A: Before taking WIKORYL SUSPENSION, inform your doctor if you have liver, kidney, lung disorders, or have intestinal obstruction.

Q: Who should not take WIKORYL SUSPENSION?

A: WIKORYL SUSPENSION is not recommended for use in patients who are allergic to Chlorpheniramine, Paracetamol, Phenylephrine, or have liver insufficiency, failure, or active liver disease; breathing problems like emphysema or chronic bronchitis, heart disease, high blood pressure, or diabetes; a condition in which there is increased pressure inside your eye; an enlarged prostate gland; problems with your adrenal gland; overactive thyroid; seizures; a blood clot that obstructs a vein; trouble sleeping; or stomach problems. Consult your doctor before taking it.

References

1. Barbara G. Wells, Joseph T. DiPiro, Terry L. Shwinghammer, Cecily V. DiPiro. Allergic Rhinitis. Pharmacotherapy Handbook. Ninth edition. Page- 813.

2. Kiran, M., Vakharia, M., Pawaskar, L., & Sheikh, S. Efficacy and safety of a fixed dose combination of paracetamol, chlorpheniramine maleate and phenylephrine in management of common cold: a phase IV, open-labelled, multi-centric study. International Journal of Basic & Clinical Pharmacology. 2018. [Accessed on 18th March 2024] https://www.ijbcp.com/index.php/ijbcp/article/view/3076

3. PubChem Compound Summary for CID 2725, Chlorpheniramine. National Center for Biotechnology Information. June 2022. [Accessed on 18th March 2024] https://pubchem.ncbi.nlm.nih.gov/compound/Chlorpheniramine#section=Mechanism-of-Action

4. Centaur Pharma. Chlorpheniramine + Paracetamol + Phenylephrine. [Accessed on 18th March 2024] https://www.centaurpharma.com/downloads/Sinarest-Oral-Drops2018.pdf

5. Pharmasynth Formulation Ltd. Chlorpheniramine + Paracetamol + Phenylephrine. [Accessed on 18th March 2024] https://pharmasynth.in/product/sedoril-kid/

6. Zuventus Healthcare Ltd. Chlorpheniramine + Paracetamol + Phenylephrine. [Accessed on 18th March 2024] http://www.zuventus.co.in/patient_wise_products_selected.aspx?Medi_Id=219

7. Ticoma Pharmacia. Chlorpheniramine + Paracetamol + Phenylephrine. [Accessed on 18th March 2024] https://www.jabsbiotech.com/product/paracetamol-phenylephrine-hydrochloride-chlorpheniramine-maleate-syrup#tab-additional_information

8. Wellona Pharma. Chlorpheniramine + Paracetamol + Phenylephrine. [Accessed on 18th March 2024] https://wellonapharma.com/product/finished/paracetamol-phenyephrine-chlorpheniramine-suspension

9. Comed Chemicals. Chlorpheniramine + Paracetamol + Phenylephrine. [Accessed on 18th March 2024] https://comedchemicals.com/product?id=22

10. Franco Indian Pharmaceuticals Pvt. Ltd. Chlorpheniramine + Paracetamol + Phenylephrine. [Accessed on 18th March 2024] http://www.francoindian.com/products/grilinctus-paediatric-syrup.htm

11. Kepler healthcare Pvt. Ltd. Chlorpheniramine + Paracetamol + Phenylephrine. [Accessed on 18th March 2024] https://keplerhealthcare.com/product/nosier-syrup/