VINLEP SUSPENSION is used alone or in combination with other anti-epileptic medicines in children and adults to manage partial seizures with or without secondarily generalised tonic-clonic seizures. It contains Oxcarbazepine which belongs to the group of medicines called Anti-epileptics.

Uses Of VINLEP SUSPENSION

It is used alone or in combination with other anti-epileptic medicines:

• To manage partial seizures with or without secondarily generalized tonic-clonic seizures

How VINLEP SUSPENSION Works

VINLEP SUSPENSION works by keeping the brain’s hyperactive nerve cells under control (by binding to sodium channels) thus reducing the chances and frequency of seizures.

How to use VINLEP SUSPENSION

• Take the medicine as advised by your physician
• Shake well before use. Use a measuring cup or a spoon to properly measure the dose
• Your doctor will decide the correct dose and duration for you depending upon your age, body weight and disease condition
• Do not stop taking the medicine unless your doctor advises you to stop

Side Effects Of VINLEP SUSPENSION

Common side effects of VINLEP SUSPENSION:

• tiredness, weakness
• headache, dizziness, drowsiness
• memory disturbances
• impaired concentration, loss of interest
• constipation, diarrhoea, stomach pain
• balance disturbance

Stop taking VINLEP SUSPENSION and contact your doctor immediately if you experience any of the following side effects:

• underactive thyroid (signs include weight gain, tiredness, hair loss, muscle weakness and feeling cold)
• anaphylactic reactions and angioedema (signs include swelling of the lips, eyelids, face, throat or mouth, leading to trouble breathing, speaking or swallowing)
• low blood sodium levels (signs include lethargy, confusion, muscle twitching or significant worsening of fits)
• decrease in the number of platelets or blood cells (signs include tiredness, shortness of breath when exercising, paleness, headache, chills, dizziness, frequent infections causing fever, sore throat, mouth ulcers, bleeding or bruising more easily than usual, nose bleeds, reddish or purplish patches or unexplained blotches on the skin)

Warning & Precautions

Pregnancy

Monitoring required

VINLEP SUSPENSION should be used with caution in pregnant women only if considered clearly necessary as there may be a risk to your baby.

Breastfeeding

Contraindicated

VINLEP SUSPENSION is not recommended for use in breastfeeding women as it may pass through breast milk.  

Driving and Using Machines

Use with Caution

Do not drive or operate any machines while taking VINLEP SUSPENSION as it may cause dizziness, sleepiness, muscle coordination problems, eye problems like double or blurred vision or depressed level of consciousness.

Alcohol

Consult your doctor

Avoid consumption of alcohol while taking VINLEP SUSPENSION as it may increase the sedative effect of this medicine.

Kidney

Use with Caution

VINLEP SUSPENSION should be taken with caution in patients with kidney disease.

Liver

Use with Caution

VINLEP SUSPENSION should be taken with caution in patients with serious liver disease.  

Allergy

Contraindicated

Do not take VINLEP SUSPENSION if you are allergic to Oxcarbazepine or any other ingredients of this medicine.

Heart Disease

Use with Caution

VINLEP SUSPENSION should be taken with caution in patients with heart disease (causing shortness of breath or swelling of the feet or legs due to fluid build-up).

Use In Pediatrics

Consult your doctor

VINLEP SUSPENSION can be used in children above 6 years of age. Your child’s doctor may monitor the thyroid function of the child before and during management with this medicine and may adjust the dose depending on the child’s body weight.

Use In Geriatrics

Use with Caution

VINLEP SUSPENSION should be used with caution in elderly patients (aged 65 years and above), especially in patients with kidney impairment.

Interactions

A. Drug-Drug interactions:

Before taking the medicine, inform your doctor if you are taking any of the following medicines:

• anticonvulsants (Ex. phenobarbital, phenytoin, carbamazepine, lamotrigine, valproic acid)
• contraceptives (Ex. ethinyl estradiol, desogestrel)
• antipsychotics (Ex. lithium, phenelzine, moclobemide)
• diuretics (Ex. furosemide, hydrochlorothiazide)
• anti-diabetic agents (Ex. desmopressin)
• non-steroidal anti-inflammatory agents (Ex. indomethacin, ibuprofen)
• immunosuppressants (Ex. ciclosporin, tacrolimus)
• anti-TB agents (Ex. rifampicin)

Overdosage:

If you or anyone else accidentally takes too much of VINLEP SUSPENSION, consult your doctor immediately or visit the nearby hospital. Overdosage symptoms are drowsiness, dizziness, problems with coordination or involuntary movement of the eyes, muscular twitching or significant worsening of fits, headache, nausea, vomiting, increased uncontrolled movements, lethargy, double or blurred vision, narrowing of the black part of the eye, tiredness, short and shallow breathing, irregular heartbeat, shaking, headache, uncontrollable movements of mouth, tongue and limbs, aggression, agitation, confusion and low blood pressure.

Synopsis

More Information

FAQs About VINLEP SUSPENSION

References

1. Barbara G. Wells, Joseph T. DiPiro, Terry L. Shwinghammer, Cecily V. DiPiro. Epilepsy. Pharmacotherapy Handbook. Ninth edition. 2015. Page-518.

2. S M Grant, D Faulds. Oxcarbazepine. A review of its pharmacology and therapeutic potential in epilepsy, trigeminal neuralgia and affective disorders. NIH. National Center for Biotechnology Information.Pubmed.gov. June 1992. [Accessed on 4th June 2022] click here

3. Charles V. Preuss, Gagandeep Randhawa, Tom Joshua P. Wy, Abdolreza Saadabadi. Oxcarbazepine. NIH. National Library of Medicine. National Center for Biotechnology Information. May 2022. [Accessed on 4th June 2022] click here

4. Novartis Pharmaceuticals UK Limited. Health Products Regulatory Authority (HPRA). [Revised in April 2022] [Accessed on 4th June 2022] click here

Author Details

Written By Srilekha. R - B.Pharm

Reviewed By Dr. Sankara Babu Gorle - MBBS, MD(Pharmacology) View profile

Last updated on 21 Nov 2024 | 03:18 PM(IST)