VASOGLAR A Combi Kit 1's
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VASOGLAR A COMBI KIT is a combination of Aspirin and Ticagrelor which belongs to the group of medicines called Antiplatelet agents. It is used to manage blood clot formation in the body following an heart attack or stroke.
It is usually prescribed to manage the recurrence of heart attack, stroke or any other circulatory disorders caused due to blood clots in patients who have undergone any heart surgeries (Ex. cardiac stent or bypass surgery) or have heart problems and/or problems in blood circulation.
Before taking VASOGLAR A COMBI KIT inform your doctor if you have any liver, kidney or heart problems. You must also inform your doctor if you have asthma, hay fever, high blood pressure, dehydration, heavy menstrual periods or if you are scheduled for any surgery (including minor dental surgeries) in the upcoming days as a precaution.
VASOGLAR A COMBI KIT is not recommended for use in patients with ulcers or bleeding from the stomach or intestines. Do not take VASOGLAR A COMBI KIT if you are pregnant or breastfeeding women.
VASOGLAR A COMBI KIT may make you bleed more easily even after minor cuts or injuries, and so be cautions while you perform even minor activities that involves such risks (like shaving, playing, or handling sharp objects).
The most common side effects of taking VASOGLAR A COMBI KIT are indigestion, joint pain, nausea, stomach pain, constipation, nose bleeds, bleeding gums, headache and dizziness. Consult your doctor if they trouble you.
Uses Of VASOGLAR A COMBI KIT
- Prevents the risk of blood clot formation in the body
- Prevents heart attack, stroke, angina or blockage of blood vessels
- Prevents the recurrence of heart complications in patients who have undergone stent implantation or any procedures to unclog blocked blood vessels supplying the heart (such as PCI)
How VASOGLAR A COMBI KIT Works
VASOGLAR A COMBI KIT is an antiplatelet medication. It manages the clumping of platelets (a type of blood cells that causes blood clot) within the blood vessels. This reduces the risk of clot formation within the blood vessels and improves blood flow to all parts of body.
How to use VASOGLAR A COMBI KIT
Take VASOGLAR A COMBI KIT as advised by your physician. Swallow the medicine with a glass of water. Do not crush or chew the medicine. It can be taken with or without meals.
Your doctor will decide the correct dose and duration of therapy for you depending upon your age, body weight and disease condition. Do not stop taking VASOGLAR A COMBI KIT without consulting your doctor.
Side Effects Of VASOGLAR A COMBI KIT
Common
- indigestion, diarrhea
- increased tendency of bleeding or bruising (including from minor cuts)
- joint pain
- headache, dizziness with spinning sensation
- nausea, constipation
- skin rash or itching
- low blood pressure (causing dizziness and blurred vision)
- nosebleeds, bleeding gums
Uncommon
- runny nose
- breathing difficulty
- confusion
- vision problems
- heavy menstrual periods
- bleeding from the ears
Rare
- inflammation of the stomach lining
- vomiting
- cramps in the lower respiratory tract
- inflammation in the blood vessels
- low blood platelet count
Stop taking VASOGLAR A COMBI KIT and contact your doctor immediately if you notice any of the following side effects:
- severe allergic reactions (such as skin rash, itching, swelling of the face, lips, throat, tongue causing difficulty in breathing or swallowing)
- severe allergic skin reactions (such as skin rash, itching, skin redness with blisters or peeling of the skin, swelling in the mouth, which may be associated with high fever and joint pains)
- unusual or prolonged bleeding tendency (such as coughing up blood, blood in urine, or black or blood-stained stools, bleeding in the stomach or bowels, unusual bleeding or bruising under the skin, nasal bleeds, bleeding in the eye, bleeding inside the head, bleeding in the lung or joints)
- excessive bleeding from small cuts or injuries
- signs of stroke (such as sudden numbness or weakness of the arm, leg or face, especially on one side of the body, confusion, difficulty in speaking or understanding others, difficulty in walking, loss of balance, sudden dizziness, severe headache
- bleeding under the skin causing red-purplish spots on the skin, with or without tiredness or jaundice
- severe shortness of breath or asthma attacks
How To Manage Side Effects
Dizziness Or Drowsiness
Try to rest and relax. Get enough sleep. Avoid driving or operating any tools or machines completely while you are feeling dizzy. Do not consume excessive alcohol, as it could aggravate your dizziness. Consult your doctor if your dizziness worsens.
Headache
Rest and relax. Keep yourself hydrated by drinking plenty of fluids such as water or electrolytes. Applying a pain-relieving balm on your forehead can be beneficial. Do not consume excessive alcohol, as it could aggravate your headache. Consult your doctor if your headache worsens.
Nausea And Vomiting
Take VASOGLAR A COMBI KIT with or just after a meal or a snack. Stick to simple meals. Avoid eating rich or spicy food. Consult your doctor if your nausea worsens.
Warning & Precautions
Pregnancy
ContraindicatedVASOGLAR A COMBI KIT is not recommended for use in pregnant women (especially during the last 3 months of pregnancy) as it may harm the unborn baby. Therefore, consult your doctor before taking it.
Breastfeeding
Monitoring requiredVASOGLAR A COMBI KIT is not recommended for use in breastfeeding women unless advised by the physician. Therefore, consult your doctor before taking it.
Driving and Using Machines
Use with CautionVASOGLAR A COMBI KIT does not affect your ability to drive or operate any machines.
Alcohol
Consult your doctorAvoid consumption of alcohol while taking VASOGLAR A COMBI KIT as it may increase the risk of side effects.
Kidney
Consult your doctorVASOGLAR A COMBI KIT is not recommended for use in patients with severe kidney problems. It should be used with caution among patients with other kidney problems. Therefore, consult your doctor before taking it.
Liver
Consult your doctorVASOGLAR A COMBI KIT is not recommended for use in patients with severe liver problems. It should be used with caution among patients with other liver problems. Therefore, consult your doctor before taking it.
Allergy
ContraindicatedDo not take VASOGLAR A COMBI KIT if you are allergic to Aspirin or Ticagrelor.
Lungs
Consult your doctorVASOGLAR A COMBI KIT is not recommended for use in patients who previously developed asthma attacks following the use of this medicine. It should be used with caution in patients with asthma or any other respiratory diseases. Therefore, consult your doctor before taking it.
Heart Disease
Use with CautionVASOGLAR A COMBI KIT should be used with caution among patients with heart problems (such as slow or irregular heart rate or having a pacemaker). Therefore, consult your doctor before taking it.
Use In Pediatrics
ContraindicatedVASOGLAR A COMBI KIT is not recommended for use in children and adolescents aged below 18 years. Therefore, consult your doctor for advice before administration.
Use In Geriatrics
Use with CautionVASOGLAR A COMBI KIT should be used with caution in elderly patients. Therefore, consult your doctor for advice before taking it.
Others
VASOGLAR A COMBI KIT is not recommended for use if you:
- currently have or ever had any ulcers in the stomach or intestines
- currently have or ever had any signs of bleeding in the gut (such as blood vomits or bloody stools)
- have bleeding in the brain
- have gout (joint pain)
- ever had stroke or mini stroke
Before taking VASOGLAR A COMBI KIT inform your doctor if you:
- have allergic rhinitis (hay fever causing repeated sneezing, watery eyes, itching of the eyes/nose and runny nose)
- have nasal polyps (a non-cancerous growth in the nose)
- have high blood pressure
- are severely dehydrated
- have G6PD deficiency
- have or previously had any problems in the stomach or intestines
- have heavy menstrual periods
- must undergo any surgery/operation in the upcoming days (including minor dental surgery)
- recently had any surgery or serious injury
- have blood clotting disorders
Interactions
A. Drug - Drug interactions:
Before taking VASOGLAR A COMBI KIT, inform your doctor if you are taking any of the following medicines such as:
- heparin, warfarin (medicines used for blood thinning)
- medicines used to manage depression (such as isocarboxazid, phenelzine, selegiline, fluoxetine, moclobemide, sertraline, nefazodone, paroxetine, sertraline and citalopram)
- methotrexate (a medicine used to manage cancer or rheumatoid arthritis)
- medicine used to suppress immune system and to manage graft rejection (such as ciclosporin or tacrolimus)
- oral contraceptives (birth control pills) Ex. mifepristone, drospirenone, ethinyl estradiol
- medicines used to manage abnormal heart rhythm (such as digoxin, quinidine, diltiazem)
- medicines used to manage fever or pain (such as ibuprofen, metamizole, naproxen)
- corticosteroids (medicines used to manage pain and inflammation) such as prednisolone
- medicines used to manage epilepsy (such as phenytoin, carbamazepine, phenobarbital and sodium valproate)
- medicines used to manage diabetes (such as glibenclamide, glipizide or insulin)
- medicines used to manage hypertension (such as ramipril, captopril, atenolol, propranolol, verapamil)
- diuretics (used to reduce edema by increasing urine output) such as spironolactone and acetazolamide
- medicines used to manage gout (such as probenecid and sulfinpyrazone)
- acetazolamide (a medicine used to manage glaucoma)
- medicines used to manage bacterial infections (such as clarithromycin, co-trimoxazole)
- medicines used to manage fungal infections (Ex. ketoconazole)
- medicines used to manage HIV infections (Ex. ritonavir, atazanavir)
- medicines used to manage high blood cholesterol levels (such as rosuvastatin, simvastatin or lovastatin)
- rifampicin (a medicine used to manage Tuberculosis)
- opioid medicines (used for pain relief) such as morphine, pethidine, fentanyl
- cisapride (a medicine used to manage heartburn)
- ergot alkaloids (used to manage migraine headaches)
- fibrinolytics (used for dissolving blood clots in the body) such as streptokinase or alteplase
Overdosage:
If you or anyone else accidentally took excessive amount of this medicine, consult your doctor or visit the nearby hospital immediately. Symptoms of overdose might include nausea, vomiting, stomach pain, ringing in the ears, vertigo, problems in hearing, headache, dizziness, confusion, sweating, flushing of arms, legs or hands with racing pulse, rapid and deep breathing and increased breathing rate.
Synopsis
| Drug | : | Aspirin, Ticagrelor |
| Pharmacological Category | : | Non-Steroidal Anti-inflammatory Drugs, Reversible P2Y12 Antagonists |
| Therapeutic Indication | : | Blood clots |
| Dosage Forms | : | Tablet, Combi kit |
More Information
- Keep VASOGLAR A COMBI KIT out of reach of children
- Store VASOGLAR A COMBI KIT in room temperature
FAQs About VASOGLAR A COMBI KIT
Q: What is VASOGLAR A COMBI KIT used for?
A: VASOGLAR A COMBI KIT is used to reduce the risk of blood clot formation in patients who have undergone surgeries or non-surgical procedures in the heart (such as PCI or stent implantation). This helps in managing the recurrence of heart attack, stroke, angina, atherosclerosis and other circulatory problems caused due to blood clots among patients with heart problems and/or problems in blood circulation.
Q: What are the side effects of VASOGLAR A COMBI KIT?
A: The most common side effects of taking VASOGLAR A COMBI KIT are increased bleeding tendency, indigestion, joint pain, nausea, stomach pain, constipation, nose bleeds, bleeding gums, headache and dizziness. Consult your doctor if they trouble you.
Q: Can I stop taking VASOGLAR A COMBI KIT once my symptoms subside?
A: No. Do not stop taking VASOGLAR A COMBI KIT without consulting your doctor. As blood clot problems is a chronic condition, long term management is necessary to control its symptoms. Therefore, take VASOGLAR A COMBI KIT as advised by your doctor for the stipulated duration. Sudden withdrawal of therapy may cause the symptoms to reappear.
Q: What should I do if I forget to take a dose of VASOGLAR A COMBI KIT?
A: If you forget to take a dose of VASOGLAR A COMBI KIT, take it as soon as you remember. However, if it is time to take the next dose, skip the missed dose of VASOGLAR A COMBI KIT and take the next one at the regular time. Do not take a double dose of VASOGLAR A COMBI KIT to compensate the missed dose.
Q: Is VASOGLAR A COMBI KIT a blood thinner?
A: Yes. VASOGLAR A COMBI KIT is a blood thinner. It manages the clumping of platelets (a type of blood cells that causes blood clot) within the blood vessels. This reduces the risk of clot or plaque formation within the blood vessels and improves blood flow to all parts of body.
Q: What precautions do I need to follow while taking VASOGLAR A COMBI KIT?
A: Before taking VASOGLAR A COMBI KIT inform your doctor if you have any liver, kidney or heart problems. You must also inform your doctor if you have asthma, hay fever, high blood pressure, dehydration, heavy menstrual periods or if you are scheduled for any surgery (including minor dental surgeries) in the upcoming days as a precaution. Do not take VASOGLAR A COMBI KIT if you have ulcers/bleeding in the stomach or intestines or if you are pregnant or breastfeeding. Avoid engaging in activities that involves risk of cuts or injuries (like shaving, playing, or handling sharp objects) as this medicine may make you bleed more.
Q: Can the use of VASOGLAR A COMBI KIT affect the liver?
A: Yes. VASOGLAR A COMBI KIT may affect the way your liver work. It can elevate the levels of certain liver enzymes in your body. Therefore, it is strictly not recommended for use in patients with severe liver diseases. It should be used with caution in patients with other minor liver problems. Therefore, consult your doctor before taking it.
Q: Should I stop taking VASOGLAR A COMBI KIT before any surgery?
A: Yes. VASOGLAR A COMBI KIT is a blood thinner which may make you bleed more easily even after minor cuts or injuries. As surgeries are always associated with increased bleeding tendency, simultaneous use of VASOGLAR A COMBI KIT is not recommended as it may make you bleed more.
References
1. KD. Tripathi. NSAIDS and Anti-pyrectics and Analgesics. Essentials of Medical Pharmacology. 7th Edition. 2013. Page – 195.
2. Jeffery I. Weitz. Modulation of Cardiovascular functions. Blood coagulation and Anticoagulant, Fibrinolytics and Anti-platelet drugs. Goodman & Gilman’s: The Pharmacological Basics of Therapeutics. Page – 871.
3. Yongjun Wang, MD; Yuesong Pan, PhD, Hao Li, PhD. Efficacy and Safety of Ticagrelor and Aspirin in Patients With Moderate Ischemic StrokeAn Exploratory Analysis of the THALES Randomized Clinical Trial. JAMA Neurology. July 2021. [Accessed on 28th February 2023] https://jamanetwork.com/journals/jamaneurology/fullarticle/2781887
4. Dexcel Pharma Ltd. Aspirin 75mg Gastro-resistant Tablets. Electronic Medicines Compendium (EMC). [Revised in May 2021] [Accessed on 28th February 2023]. https://www.medicines.org.uk/emc/files/pil.2614.pdf
5. AstraZeneca AB. Brilique® 90 mg film-coated tablets ticagrelor. Electronic Medicines Compendium (EMC). [Revised in August 2022] [Accessed on 28th February 2023] https://www.medicines.org.uk/emc/files/pil.5767.pdf
6. Torrent Pharmaceuticals Ltd. Torplat A Copack. [Revised in March 2021]. [Accessed on 28th February 2023] https://www.torrentian.com/pisheet/Upload/PI_Sheet/3015.pdf
Useful Diagnostic Tests
- Activated Partial Thromboplastin Time
- Complete Blood Count
- Prothrombin Time
Author Details
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