Introduction About VALZAAR H 80MG TABLET

VALZAAR H 80MG TABLET is a combination of Hydrochlorothiazide and Valsartan which belongs to the group of medicines called Antihypertensive agents. It is used to manage hypertension (high blood pressure) when management with single agents is not effective.

Hypertension (also known as high blood pressure) is a medical condition in which the force of the blood exerted against the walls of the artery remains very high, and as a result it may lead to severe damage to the blood vessels supplying several vital organs, such as heart, kidney, or brain. If left unmanageed, it may cause serious complications such as heart attack, heart failure, stroke or even blindness.

By lowering blood pressure, VALZAAR H 80MG TABLET can also reduce the risk of heart attack, (myocardial infarction), kidney failure or stroke.

During management with VALZAAR H 80MG TABLET your doctor will constantly monitor your kidney functions, blood pressure, electrolyte levels and blood sugar levels to avoid the risk of unwanted side effects.

Before taking VALZAAR H 80MG TABLET inform your doctor if you have any heart, liver, or kidney problems. You must also inform your doctor if you have diabetes, high blood cholesterol levels, low blood pressure or are severely dehydrated due to excessive vomiting or diarrhea.

VALZAAR H 80MG TABLET is also not suitable for use in pregnant or breastfeeding women as it may cause serious harm to the growing baby. Stop taking VALZAAR H 80MG TABLET and inform your doctor immediately if you become pregnant while undergoing therapy with VALZAAR H 80MG TABLET.

The most common side effects of taking VALZAAR H 80MG TABLET are low blood pressure, dizziness, low or high blood potassium levels, muscle pain, diarrhoea, dry mouth, erectile dysfunction and increased blood uric acid levels. Contact your doctor if any of these side effect worsens.

Uses Of VALZAAR H 80MG TABLET

• Manage Hypertension (high blood pressure)
• Prevents the risk of heart attack, kidney failure or stroke

How VALZAAR H 80MG TABLET Works

VALZAAR H 80MG TABLET is an antihypertensive medicine. It relaxes your blood vessels and improves blood flow across them. It also reduces thickness of the blood by removing excess fluids from the body in the form of urine. Collectively, these actions reduce the strain on the heart and helps the heart to pump blood more smoothly with less pressure.

How to use VALZAAR H 80MG TABLET

Take VALZAAR H 80MG TABLET as directed by your physician. Swallow the medicine with a glass of water. Do not crush or chew the medicine.

Try to take VALZAAR H 80MG TABLET at the same time each day. VALZAAR H 80MG TABLET can be taken with or without food.

Your doctor will decide the correct dose and duration of therapy for you depending upon your age, body weight and health condition.

Continue to take VALZAAR H 80MG TABLET for the stipulated duration instructed by your doctor without any interruption to achieve better results.

Side Effects Of VALZAAR H 80MG TABLET

How To Manage Side Effects

Nausea and vomiting:

Take VALZAAR H 80MG TABLET with or just after a meal or a snack. Stick to simple meals. Avoid eating rich or spicy food. Consult your doctor if your nausea worsens.

Dizziness:

Try to rest and relax. Get enough sleep. Avoid driving or operating any tools or machines completely while you are feeling dizzy. Do not consume excessive alcohol, as it could aggravate your dizziness. Consult your doctor if your dizziness worsens.

Headache:  

Rest and relax. Keep yourself hydrated by drinking plenty of fluids such as water or electrolytes. Applying a pain-relieving balm on your forehead can be beneficial. Do not consume excessive alcohol, as it could aggravate your headache. Consult your doctor if your headache worsens.

Warning & Precautions

Pregnancy

VALZAAR H 80MG TABLET is not recommended for use in pregnant women as it may cause serious harm to the growing fetus. Therefore, inform your doctor before taking VALZAAR H 80MG TABLET if you are pregnant, think you may be pregnant or planning to have a baby. If you become pregnant while undergoing therapy with VALZAAR H 80MG TABLET, stop taking it and consult your doctor immediately.

Breastfeeding

VALZAAR H 80MG TABLET is not recommended for use in breastfeeding women. Therefore, consult your doctor before taking it.

Driving and Using Machines

Do not drive or handle any heavy tools or machines if you experience dizziness or drowsiness after taking VALZAAR H 80MG TABLET.

Alcohol

Avoid consumption of alcohol while taking VALZAAR H 80MG TABLET as it might make you feel dizzier and drowsier.

Kidney

VALZAAR H 80MG TABLET is not recommended for use in patients with severe kidney problems. It should be used with caution in patients with other kidney problems (such as kidney transplant, narrowing of renal arteries). Therefore, consult your doctor before taking it.

Liver

VALZAAR H 80MG TABLET is not recommended for use in patients with severe liver impairment (such as cholestasis, jaundice, biliary obstruction). It should be used with caution in patients with mild to moderate liver problems. Therefore, consult your doctor before taking it.

Allergy

Do not take VALZAAR H 80MG TABLET if you are allergic to Valsartan or Hydrochlorothiazide.

Lungs

VALZAAR H 80MG TABLET should be used with caution in patients with breathing problems. Therefore, consult your doctor before taking it.

Heart Disease

VALZAAR H 80MG TABLET should be used with caution in patients with heart problems (such as irregular heart rhythm, heart failure, problems with heart muscle or valves). Therefore, consult your doctor before taking it.

Interactions

A. Drug - Drug interactions:

• antidepressants such as lithium, citalopram, fluoxetine, paroxetine, nefazodone, St. John’s wort (herbal medicine used to manage depression)
• other medicines used to manage elevated blood pressure (such as aliskiren, bosentan, methyldopa, guanethidine, captopril, enalapril, lisinopril, verapamil, diltiazem, losartan, valsartan)
• potassium supplements or potassium-sparing diuretics such as spironolactone, triamterene or amiloride (used to retain or increase potassium levels in the body)
• non-steroidal anti-inflammatory drugs (used for pain relief) such as indomethacin, celecoxib, ibuprofen, aspirin
• heparin (a medicine used to manage or manage blood clots)
• medicines used to manage bacterial infections (Ex. erythromycin, clarithromycin, telithromycin, trimethoprim, sparfloxacin, pentamidine, penicillin-G)
• baclofen (a medicine used for relaxing muscles)
• amifostine (a kidney protectant used along with chemotherapeutic agents)
• medicines used to manage mental disorders such as depression, psychosis, or anxiety (Ex. pimozide, amisulpride, haloperidol)
• corticosteroids (used to manage inflammation) Ex. prednisolone
• amphotericin B (a medicine used to manage fungal infections)
• carbenoxolone (a medicine used to manage mouth ulcers)
• allopurinol (a medicine used to manage gout)
• cyclophosphamide or methotrexate (medicine used to manage cancer)
• laxatives (used to manage constipation) Ex. lactulose
• corticotropin (a medicine used to correct hormone problems)
• medicines used to lower blood cholesterol levels (such as cholestyramine and colestipol)
• insulin, metformin (medicines used to manage diabetes)
• noradrenaline (a medicine used to increased blood pressure)
• tubocurarine, dantrolene (medicine used as a muscle relaxant)
• calcium supplements and/or vitamin D supplements
• atropine or biperiden used for abdominal or stomach spasms or cramps
• amantadine (medicine used to manage Parkinson’s disease)
• medicines to control the heart rhythm (Ex. quinidine, disopyramide, amiodarone, sotalol, digoxin)
• medicines used to manage mental disorders (Ex. thioridazine, chlorpromazine, levomepromazine)
• medicines used to manage allergic reactions (Ex. terfenadine)

Overdosage:

If you or anyone else accidentally took more VALZAAR H 80MG TABLET, consult your doctor immediately. Overdosage may cause low blood pressure, abnormal heartbeat, dizziness, vomiting, decreased kidney functions, nausea, sleepiness and muscle cramps.

Synopsis

More Information

• Keep VALZAAR H 80MG TABLET out of reach of children
• Store VALZAAR H 80MG TABLET at room temperature

FAQs About VALZAAR H 80MG TABLET

What are the uses of VALZAAR H 80MG TABLET?

VALZAAR H 80MG TABLET is used to manage hypertension. It can also be used to manage the risk of heart attack or stroke.

What type of a medicine is VALZAAR H 80MG TABLET?

VALZAAR H 80MG TABLET is an antihypertensive medicine. It relaxes your blood vessels and improves blood flow across them. It also reduces thickness of the blood by removing excess fluids from the body in the form of urine. Collectively, it reduces the strain on the heart and helps the heart to pump blood more smoothly with less pressure.

What happens when I stop taking VALZAAR H 80MG TABLET?

Do not stop taking VALZAAR H 80MG TABLET without consulting your doctor as your blood pressure may raise once again. Make sure to take VALZAAR H 80MG TABLET for the stipulated duration recommended by your doctor to achieve maximum results.

What is the best time to take VALZAAR H 80MG TABLET?

VALZAAR H 80MG TABLET can be taken with or without meals. Your doctor will decide the best time for you to take VALZAAR H 80MG TABLET based on your age, body weight and disease condition.

What to do if I forgot to take a dose of VALZAAR H 80MG TABLET?

If you forgot to take a dose of VALZAAR H 80MG TABLET, take it as soon as you remember. However, if it is time for the next dose of VALZAAR H 80MG TABLET, skip the missed dose and take the next one regularly. Do not take a double dose of VALZAAR H 80MG TABLET to compensate the missed ones.

What precautions should be followed while taking VALZAAR H 80MG TABLET?

Before taking VALZAAR H 80MG TABLET, inform your doctor if you have any heart, liver or kidney problems. You must also inform your doctor if you have diabetes, low blood pressure volume or are severely dehydrated. Stop taking VALZAAR H 80MG TABLET and consult your doctor immediately if you become pregnant. Regularly visit your doctor and take all the necessary blood test recommended by your doctor without fail.

Can I consume alcohol while taking VALZAAR H 80MG TABLET?

Avoid consumption of alcohol while taking VALZAAR H 80MG TABLET as it might make you feel dizzier and drowsier.

What happens if I accidentally take more VALZAAR H 80MG TABLET?

If you or anyone else accidentally took more VALZAAR H 80MG TABLET, consult your doctor immediately. Overdosage may cause low blood pressure, abnormal heartbeat, dizziness, vomiting, decreased kidney functions, nausea, sleepiness and muscle cramps.

Can I take VALZAAR H 80MG TABLET daily?

Take VALZAAR H 80MG TABLET as advised by your physician. Your doctor will evaluate your health condition and suggests whether can you take VALZAAR H 80MG TABLET every day or not.

Is VALZAAR H 80MG TABLET safe to use in diabetic patients?

VALZAAR H 80MG TABLET may alter the blood sugar levels in your body. Therefore, it is necessary to inform your doctor if you have diabetes before taking VALZAAR H 80MG TABLET as a precaution. Your doctor will closely monitor you blood sugar levels to avoid the risk of side effects.

What are the side effects of VALZAAR H 80MG TABLET?

The most common side effects of taking VALZAAR H 80MG TABLET are low blood pressure, dizziness, low or high blood potassium levels, muscle pain, diarrhoea, dry mouth, erectile dysfunction and increased blood uric acid levels. Contact your doctor if any of these side effect worsens.

Can I stop taking VALZAAR H 80MG TABLET once my symptoms subside?

No. Do not stop taking VALZAAR H 80MG TABLET without consulting your doctor. As hypertension is a chronic condition, long term management may be necessary to control its symptoms. Therefore, take VALZAAR H 80MG TABLET as advised by your doctor for the stipulated duration. Premature discontinuation of therapy may increase your blood pressure once again.

Can VALZAAR H 80MG TABLET be taken during pregnancy?

VALZAAR H 80MG TABLET is not recommended for use in pregnant women as it may cause serious harm to the growing fetus. Therefore, inform your doctor before taking VALZAAR H 80MG TABLET if you are pregnant, think you may be pregnant or planning to have a baby. If you become pregnant while undergoing therapy with VALZAAR H 80MG TABLET, stop taking it and consult your doctor immediately.

Is VALZAAR H 80MG TABLET safe to use in kidney disease?

VALZAAR H 80MG TABLET is not recommended for use in patients with severe kidney problems. It should be used with caution in patients with other kidney problems (such as kidney transplant, narrowing of renal arteries). Your doctor will access your health condition and suggest a suitable dose for you. Therefore, it is important to inform your doctor if you have any kidney problems before taking VALZAAR H 80MG TABLET as a precaution.

Can the use of VALZAAR H 80MG TABLET affect the liver?

Yes. VALZAAR H 80MG TABLET may affect the way your liver work. It can elevate the levels of certain liver enzymes in your body. Therefore, it is strictly not recommended for use in patients with severe liver diseases. It should be used with caution in patients with other minor liver problems. Consult your doctor before taking it.

References

1. KD. Tripathi. Antihypertensive Drugs. Drugs Affecting Renin-Angiotensin System and Plasma Kinins. Essentials of medical pharmacology. Seventh edition. 2013. Page – 559, 561 & 562.

2. D H Zappe, B F Palmer, D Purkayastha, R Samuel and K A Jamerson. Effectiveness of initiating treatment with valsartan/hydrochlorothiazide in patients with stage-1 or stage-2 hypertension. NIH. National Library of Medicine. National Center for Biotechnology Information. PMC. PubMed Central. December 2009. [Accessed on 14th December 2022] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2898539/

3. APL Swift Services (Malta) Limited. Electronic Medicines Compendium (EMC). [Revised in November 2021] [Accessed on 14th December 2022] https://www.medicines.org.uk/emc/files/pil.13420.pdf?view=pil

4. Alembic Pharmaceuticals Inc. Valsartan and Hydrochlorothiazide, Tablet, Film coated. Dailymed.com. [Revised in July 2021]. [Accessed on 14th December 2022] https://dailymed.nlm.nih.gov/dailymed/lookup.cfm?setid=973973a3-9fec-4afc-910f-187f099dfe2d

5. Central Drugs Standard Control Organization. Valsartan 80mg/160mg/160mg+HCTZ 12.5mg/12.5mg/25mg tablet. March 2003. [Accessed on 14th December 2022] https://cdsco.gov.in/opencms/resources/UploadCDSCOWeb/2018/UploadApprovalNewDrugs/dciApprovedfdc.pdf

Useful Diagnostic Tests

• Kidney Function Test

Author Details

Written By Srilekha. R - B.Pharm

Reviewed By Dr. Sankara Babu Gorle - MBBS, MD(Pharmacology) View profile

Last updated on 17 Dec 2022 | 05:04 PM(IST)