Valembic 80 AM Tablet 10'S
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INTRODUCTION
VALEMBIC 80 AM is a combination of Amlodipine and Valsartan which belongs to the group of medicines called Antihypertensive agents. It is used to manage hypertension (high blood pressure) when management with single agents is not effective.
Hypertension (also known as high blood pressure) is a medical condition in which the force of the blood exerted against the walls of the artery remains very high, and as a result it may lead to severe damage to the blood vessels supplying several vital organs, like heart, kidney, or brain. If left unmanageed, it may cause serious complications such as heart attack, heart failure, stroke or even blindness. By lowering blood pressure, VALEMBIC 80 AM can also reduce the risk of heart attack (myocardial infarction) or stroke.
Amlodipine is a calcium channel blocker and valsartan is an angiotensin II receptor blocker. They both act by relaxing the blood vessels supplying the various vital organs. This allows blood to flow more smoothly across the blood vessels which in turn reduces the strain on the heart and helps the heart to pump more blood smoothly with less pressure.
During management with VALEMBIC 80 AM your doctor will constantly monitor your kidney functions, blood pressure and blood sugar levels to avoid the risk of unwanted side effects. Also, avoid eating grapefruit or drinking grapefruit juice while taking VALEMBIC 80 AM as it may increase the risk of side effects.
Before taking VALEMBIC 80 AM inform your doctor if you have any heart, liver, or kidney problems. You must also inform your doctor if you have diabetes, low blood pressure or are severely dehydrated due to excessive vomiting or diarrhea.
VALEMBIC 80 AM is also not suitable for use in pregnant or breastfeeding women as it may cause serious harm to the growing baby. Stop taking VALEMBIC 80 AM and inform your doctor immediately if you become pregnant while undergoing therapy with VALEMBIC 80 AM.
The most common side effects of taking VALEMBIC 80 AM are low blood pressure, dizziness, tiredness, headache, sleepiness, swollen ankles, and flushing. Contact your doctor if any of these side effect worsens.
USES OF VALEMBIC 80 AM
- Manages Hypertension (high blood pressure)
HOW VALEMBIC 80 AM WORKS
VALEMBIC 80 AM effectively controls blood pressure in patients with hypertension. It contains two medicines namely, amlodipine and valsartan. Valsartan blocks the actions of certain hormones (angiotensin-II) in the body that causes narrowing of blood vessels and increase in blood pressure.
Amlodipine is a vasodilator. It relaxes the blood vessels by blocking the entry of certain ions (calcium ions) within them that causes narrowing. This allows blood to flow more smoothly across the blood vessels. Collectively, they reduce the strain on the heart and helps the heart to pump more blood smoothly with less pressure.
DIRECTIONS FOR USE
Take VALEMBIC 80 AM as directed by your physician. Swallow the medicine with a glass of water. Do not crush or chew the medicine. Try to take VALEMBIC 80 AM at the same time each day.
Your doctor will decide the correct dose and duration of therapy for you depending upon your age, body weight and health condition. Continue to take VALEMBIC 80 AM for the stipulated duration instructed by your doctor without any interruption to achieve better results.
SIDE EFFECTS OF VALEMBIC 80 AM
COMMON
- low blood pressure
- swelling of ankles and legs (edema)
- headache, dizziness
- nausea, vomiting, stomach pain, constipation, diarrhea, indigestion
- sleepiness
- abnormal heartbeat (fast or slow)
- muscle cramps
- flushing (warmth and redness of face and neck)
- feeling tired or weak
- vision problems
UNCOMMON
- urinary tract infections, difficulty in passing urine, urge to urinate
- sore throat, common cold
- high blood potassium levels (causing muscle weakness, irregular heartbeat, chest pain)
- difficulty in falling asleep
- feeling depressed or anxious, changes in mood
- vertigo (spinning sensation), shakiness
- orthostatic hypotension (dizziness while standing up from sitting or lying position)
- increased sweating
- back pain, tingling of numbness of body parts
- changes in taste
- ringing in the ears
- dry nose, dry mouth
- hair loss
- impotence (inability to obtain an erection), breast enlargement in men
- changes in body weight
RARE
Stop taking VALEMBIC 80 AM and contact your doctor immediately if you experience any of the following side effects such as:
- signs of allergic reactions (such as skin rash, swelling of the face, lips, mouth, or throat which can lead to difficulty in breathing or swallowing)
- severe skin reactions (such as skin rash with itching and redness, blistering and peeling of skin, skin swelling and inflammation of mucous membrane)
- chest pain, shortness of breath
- inflammation of pancreas (causing severe stomach pain that radiates to the back side of the body)
HOW TO MANAGE SIDE EFFECTS
Nausea and Vomiting:
Take VALEMBIC 80 AM with or just after a meal or a snack. Stick to simple meals. Avoid eating rich or spicy food. Consult your doctor if your nausea worsens.
Dizziness:
Try to rest and relax. Get enough sleep. Avoid driving or operating any tools or machines completely while you are feeling dizzy. Do not consume excessive alcohol, as it could aggravate your dizziness. Consult your doctor if your dizziness worsens.
Headache:
Rest and relax. Keep yourself hydrated by drinking plenty of fluids such as water or electrolytes. Applying a pain-relieving balm on your forehead can be beneficial. Do not consume excessive alcohol, as it could aggravate your headache. Consult your doctor if your headache worsens.
WARNING & PRECAUTIONS
PREGNANCY
VALEMBIC 80 AM is not recommended for use in pregnant women as it may cause serious harm to the growing fetus. Therefore, inform your doctor before taking VALEMBIC 80 AM if you are pregnant, think you may be pregnant or planning to have a baby. If you become pregnant while undergoing therapy with VALEMBIC 80 AM, stop taking it and consult your doctor immediately.
BREASTFEEDING
VALEMBIC 80 AM is not recommended for use in breastfeeding women. Therefore, consult your doctor before taking it.
DRIVING AND USING MACHINES
Do not drive or handle any heavy tools or machines if you experience dizziness or drowsiness after taking VALEMBIC 80 AM.
ALCOHOL
Avoid consumption of alcohol while taking VALEMBIC 80 AM as it might make you feel dizzier and drowsier.
KIDNEY
VALEMBIC 80 AM should be used with caution in patients with kidney problems (such as kidney transplant, narrowing of renal arteries). Therefore, consult your doctor before taking it.
LIVER
VALEMBIC 80 AM is not recommended for use in patients with severe liver impairment (such as cholestasis, jaundice, biliary obstruction). It should be used with caution in patients with mild to moderate liver problems. Therefore, consult your doctor before taking it.
ALLERGY
Do not take VALEMBIC 80 AM if you are allergic to Amlodipine or Valsartan.
HEART DISEASE
VALEMBIC 80 AM should be used with caution in patients with heart problems (such as irregular heart rhythm, heart failure, recent heart attack, and problems with heart muscle or valves). Therefore, consult your doctor before taking it.
OTHERS
VALEMBIC 80 AM is not recommended for use if you:
- have cardiogenic shock (heart cannot pump blood suddenly)
- have diabetes related kidney problems
Before taking VALEMBIC 80 AM, inform your doctor if you:
- have primary hyperaldosteronism (problems in adrenal gland)
- have low blood pressure or are severely dehydrated (due to diarrhea, vomiting or excess sweating)
- have diabetes
- have hyperkalemia (high blood potassium levels)
- have unstable angina (a type of chest pain)
- have narrowing of arteries
Use in pediatrics:
VALEMBIC 80 AM should be used in children and adolescents (aged between 6-18 years) only if prescribed by the physician. Therefore, consult your doctor for advice.
Use in geriatrics:
VALEMBIC 80 AM should be used with caution in the elderly patients. Therefore, consult your doctor before taking it.
INTERACTIONS
A. Drug-Drug Interaction:
Before taking VALEMBIC 80 AM, inform your doctor if you are taking any of the following:
- other medicines used to manage elevated blood pressure (such as aliskiren, captopril, enalapril, lisinopril, verapamil, diltiazem, losartan, valsartan)
- lithium, St. John’s wort (medicines used to manage depression)
- potassium supplements or potassium-sparing diuretics such as spironolactone, triamterene or amiloride (used to retain or increase potassium levels in the body)
- non-steroidal anti-inflammatory drugs (used for pain relief) such as indomethacin, celecoxib, ibuprofen, aspirin
- heparin (a medicine used to prevent or manage blood clots)
- medicines used to manage bacterial infections (Ex. erythromycin, clarithromycin, telithromycin, trimethoprim)
- medicines to suppress immune system (Ex. cyclosporin, tacrolimus, sirolimus, temsirolimus and everolimus)
- dantrolene (a medicine used to manage muscle spasm)
- medicine used to manage HIV infection (Ex. indinavir, ritonavir, saquinavir)
- medicines used to manage fungal infections (Ex. itraconazole, ketoconazole and fluconazole)
- digoxin (a medicine used to manage irregular heartbeat)
- simvastatin (a medicine used to lower blood cholesterol levels)
- baclofen (a medicine used for relaxing muscles)
- amifostine (a kidney protectant used along with chemotherapeutic agents)
- medicines used to manage mental disorders such as depression, psychosis, or anxiety (Ex. pimozide, amisulpride, haloperidol)
- corticosteroids (used to manage inflammation) Ex. prednisolone
B. Drug-Food Interaction:
Do not eat grapefruit or drink grapefruit juice while taking VALEMBIC 80 AM as it may increase the risk of side effects.
Overdosage:
If you or anyone else accidentally took more VALEMBIC 80 AM, consult your doctor immediately. Overdosage may cause low blood pressure, abnormal heartbeat, and dizziness.
SYNOPSIS
| Drug | : | Amlodipine, Valsartan |
| Pharmacological Category | : | Calcium channel blocker, Angiotensin II blockers |
| Therapeutic Indication | : | Hypertension |
| Dosage Forms | : | Tablet |
MORE INFORMATION
- Keep VALEMBIC 80 AM out of reach of children
- Store VALEMBIC 80 AM at room temperature
FAQs ABOUT VALEMBIC 80 AM
What are the uses of VALEMBIC 80 AM?
VALEMBIC 80 AM is used to manage hypertension in adults.
What type of a medicine is VALEMBIC 80 AM?
VALEMBIC 80 AM is an antihypertensive medicine. It is a combination of two medicines namely amlodipine and valsartan. Amlodipine is a calcium channel blocker and valsartan is a angiotensin-II receptor blocker. They both reduces strain on the heart, relaxes blood vessels and makes the heart to pump more blood with lesser force.
What happens when I stop taking VALEMBIC 80 AM?
Do not stop taking VALEMBIC 80 AM without consulting your doctor as your blood pressure may raise once again. Make sure to take VALEMBIC 80 AM for the stipulated duration recommended by your doctor to achieve maximum results.
What is the best time to take VALEMBIC 80 AM?
VALEMBIC 80 AM can be taken with or without meals. Your doctor will decide the best time for you to take VALEMBIC 80 AM based on your age, body weight and disease condition.
What to do if I forgot to take a dose of VALEMBIC 80 AM?
If you have missed a dose of VALEMBIC 80 AM, take it as soon as you remember. However, if it is time for the next dose of VALEMBIC 80 AM, skip the missed dose and take the next one regularly. Do not take a double dose of VALEMBIC 80 AM to compensate the missed ones.
What precautions should be followed while taking VALEMBIC 80 AM?
Before taking VALEMBIC 80 AM, inform your doctor if you have any heart, liver, or kidney problems. You must also inform your doctor if you have diabetes, low blood pressure volume or are severely dehydrated. Stop taking VALEMBIC 80 AM and consult your doctor immediately if you become pregnant. Regularly visit your doctor and take all the necessary blood test recommended by your doctor without fail.
Can I consume alcohol while taking VALEMBIC 80 AM?
Avoid consumption of alcohol while taking VALEMBIC 80 AM as it might make you feel dizzier and drowsier.
What happens if I accidentally take more VALEMBIC 80 AM?
If you or anyone else accidentally took more VALEMBIC 80 AM, consult your doctor immediately. Overdosage may cause low blood pressure, abnormal heartbeat, fainting, drowsiness, nausea, vomiting or confusion.
Can I take VALEMBIC 80 AM daily?
Take VALEMBIC 80 AM as advised by your physician. Your doctor will evaluate your health condition and suggests whether can you take VALEMBIC 80 AM every day or not.
Is VALEMBIC 80 AM safe to use in diabetic patients?
VALEMBIC 80 AM may alter the blood sugar levels in your body. Therefore, it is necessary to inform your doctor if you have diabetes before taking VALEMBIC 80 AM as a precaution. Your doctor will closely monitor you blood sugar levels to avoid the risk of side effects.
What are the side effects of VALEMBIC 80 AM?
The most common side effects of taking VALEMBIC 80 AM are low blood pressure, dizziness, tiredness, headache, sleepiness, swollen ankles, and flushing. Contact your doctor if any of these side effect worsens.
Can I stop taking VALEMBIC 80 AM once my symptoms subside?
No. Do not stop taking VALEMBIC 80 AM without consulting your doctor. As hypertension is a chronic condition, long term management may be necessary to control its symptoms. Therefore, take VALEMBIC 80 AM as advised by your doctor for the stipulated duration. Premature discontinuation of therapy may increase your blood pressure once again.
Can VALEMBIC 80 AM be taken during pregnancy?
VALEMBIC 80 AM is not recommended for use in pregnant women as it may cause serious harm to the growing fetus. Therefore, inform your doctor before taking VALEMBIC 80 AM if you are pregnant, think you may be pregnant or planning to have a baby. If you become pregnant while undergoing therapy with VALEMBIC 80 AM, stop taking it and consult your doctor immediately.
Is VALEMBIC 80 AM safe to use in kidney disease?
VALEMBIC 80 AM should be used with caution in patients with kidney diseases (such as those having renal artery stenosis, kidney transplant or in those undergoing haemodialysis). Your doctor will access your health condition and suggest a suitable dose for you. Therefore, it is important to inform your doctor if you have any kidney problems before taking VALEMBIC 80 AM as a precaution.
Can the use of VALEMBIC 80 AM affect the liver?
Yes. VALEMBIC 80 AM may affect the way your liver work. It can elevate the levels of certain liver enzymes in your body. Therefore, it is strictly not recommended for use in patients with severe liver diseases. It should be used with caution in patients with other minor liver problems. Consult your doctor before taking it.
REFERENCES
1. KD Tripathi. Antihypertensive drugs. Essentials of Medical Pharmacology. Seventh edition. 2013. Page – 561 &562.
2. Khalid M Khan, Somia Iqtadar, Mahmood Nasir, Anum S Siddiqui, and Atiq Rehman. Amlodipine/Valsartan (Avsar®): Efficacy in Hypertensive Patients - A Real World Observational Study (ALERT). NIH. National Library of Health. National Center of Biotechnology Information. PMC PubMed Central. May 2020. [Accessed on 14th July 2022] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7299538/
3. Novartis Farmacéutica SA. Electronic Medicines Compendium (EMC). [Revised in July 2019] [Accessed on 14th July 2022] https://www.medicines.org.uk/emc/files/pil.7771.pdf
4. Dr. Reddy’s Laboratories (UK) Ltd. Electronic Medicines Compendium (EMC). [Revised in August 2018] [Accessed on 14th July 2022] https://www.medicines.org.uk/emc/files/pil.3478.pdf
5. McDermott Laboratories Ltd. Electronic Medicines Compendium (EMC). [Revised in May 2021] [Accessed on 14th July 2022] https://www.medicines.org.uk/emc/files/pil.8178.pdf
USEFUL DIAGNOSTIC TESTS
- Kidney Function Test
The contents of this website are for informational purposes only and not intended to be a substitute for professional medical advice, diagnosis, or treatment. Please seek the advice of a physician or other qualified health provider with any questions you may have regarding a medical condition. Do not disregard professional medical advice or delay in seeking it because of something you have read on this website.
