THIOBLIS 4 Tablet 10's
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Introduction About THIOBLIS 4 TABLET
THIOBLIS 4 TABLETcontains Thiocolchicoside, which belongs to the group of medicines called Muscle relaxants. It is used in adults and adolescents over 16 years of age to manage painful muscle contractions and for acute painful conditions related to the spine. Muscle spasms (muscle cramps) are painful contractions and tightening of your muscles. They’re common, involuntary, and unpredictable. The symptoms may include swelling, pain, stiffness, tenderness, and fatigue.
Your doctor may advise you to take relevant tests to understand your condition. Before taking THIOBLIS 4 TABLET, inform your doctor if you have flaccid paralysis (sagging of the face), muscular hypotonia (weak muscles), diarrhoea, lactose intolerance, seizure, or epilepsy.
THIOBLIS 4 TABLET is not recommended for use by pregnant or breastfeeding women. THIOBLIS 4 TABLET should not be used by children or adolescents under the age of 16. The most common side effects of taking THIOBLIS 4 TABLET are skin allergic reactions, drowsiness, diarrhea, and gastric symptoms. Consult your doctor if your symptoms get worse or persist.
Uses Of THIOBLIS 4 TABLET
- painful muscle contractions
- acute painful conditions related to the spine
How THIOBLIS 4 TABLET Works
THIOBLIS 4 TABLET works through selective binding to the GABA-A receptor (neurotransmitter). It manages muscle contractions by activating the GABA-inhibitory motor pathway and inhibiting the glycine receptors (neurotransmitters). Thus, relaxing the muscle pain and spasms.
How to use THIOBLIS 4 TABLET
Take THIOBLIS 4 TABLET as advised by your physician. Swallow the medicine with a glass of water. Do not crush or chew the medicine. Your doctor will decide the right dose and duration depending on your age, body weight and disease condition.
Side Effects Of THIOBLIS 4 TABLET
Common
- digestive disorders such as diarrhea and stomach pain
- gastralgia
- drowsiness
Uncommon
- itching, redness, bumps, vesicles or blisters on the skin
- allergic skin reaction
- nausea and vomiting
Rare
- allergic skin reactions like hives/urticaria
Stop taking THIOBLIS 4 TABLET and contact your doctor immediately if you experience any of the following side effects:
- seizures
- signs of a liver problem (loss of appetite, nausea or vomiting, abdominal discomfort, unexplained fatigue, dark-coloured urine, jaundice, fever, itching)
- angioedema (sudden swelling of the neck and face, possibly causing difficulty breathing)
- anaphylactic shock (drop in blood pressure, possibly preceded by an eruption of bumps, itching, redness of the skin, difficulty breathing, swelling of the face and/or neck)
How To Manage Side Effects
Nausea
Try to take THIOBLIS 4 TABLET with or just after a meal or a snack. Stick to simple meals. Avoid eating rich or spicy food. Consult your doctor if your symptom gets worse.
Itchy skin:
Avoid taking hot showers as they can irritate the skin. Do not scratch the affected area. Use sunscreen and protective clothing when going outdoors or use unscented moisturizers to soothe and hydrate the skin. Consult your doctor if your symptom gets worse.
Diarrhoea:
Drink plenty of water or fruit juices to keep yourself hydrated. Don’t take any medicine on your own to manage diarrhoea. Consult your doctor if your symptom gets worse.
Warning & Precautions
Pregnancy
THIOBLIS 4 TABLET is not recommended for use in pregnant women, women planning to have a baby or women of childbearing potential who are not taking contraceptives. Consult your doctor before taking THIOBLIS 4 TABLET.
Breastfeeding
THIOBLIS 4 TABLET is not recommended for use by breastfeeding women. Consult your doctor before taking THIOBLIS 4 TABLET.
Driving and Using Machines
Do not drive or use machines while taking THIOBLIS 4 TABLET as it can make you drowsy. Consult your doctor for advice.
Allergy
Do not take THIOBLIS 4 TABLET if you are allergic to Thiocolchicoside or any other ingredients of this medicine.
Others
THIOBLIS 4 TABLET is not recommended for use if you:
- flaccid paralysis (sagging face)
- muscular hypotonia (muscle weakness)
Before taking THIOBLIS 4 TABLET, inform your doctor if you:
- have diarrhea
- have epilepsy or risk of seizure
- lactose intolerant
Use in pediatrics:
THIOBLIS 4 TABLET is not recommended for use in children below 16 years of age. Consult your doctor before taking THIOBLIS 4 TABLET.
Interactions
A. Drug-Drug interactions:
Before taking THIOBLIS 4 TABLET, inform your doctor if you are taking any of the following medicine:
- taking or have taken any other medicines, muscle relaxants or central nervous system sedatives
Overdosage:
If you or anyone else accidentally take too much of THIOBLIS 4 TABLET, consult your doctor immediately or visit the nearby hospital.
Synopsis
| Drug | : | Thiocolchicoside |
| Pharmacological Category | : | Triaminopyridines |
| Therapeutic Indication | : | Painful muscle contractions, Acute painful conditions related to the spine |
| Dosage Forms | : | Gel, Tablet, Capsule, Injection |
More Information
- Keep THIOBLIS 4 TABLET out of reach from children
- Store at room temperature
FAQs About THIOBLIS 4 TABLET
What is THIOBLIS 4 TABLET used for?
THIOBLIS 4 TABLET is used as an add-on therapy in adults and adolescents 16 years of age and older for painful muscle contractions and acute painful spine conditions.
Can THIOBLIS 4 TABLET be used by children?
No, THIOBLIS 4 TABLET should not be used by children under the age of 16. Consult your doctor before taking THIOBLIS 4 TABLET.
How does THIOBLIS 4 TABLET work?
THIOBLIS 4 TABLET works through selective binding to the GABA-A receptor (a neurotransmitter). It manages muscle contractions by activating the GABA-inhibitory motor pathway and inhibiting the glycine receptors (neurotransmitters). Thus, relaxing the muscle pain and spasms.
When is THIOBLIS 4 TABLET contraindicated?
THIOBLIS 4 TABLET is not recommended for use in patients with flaccid paralysis, muscular hypotonia, or hypersensitivity to this medicine. Consult your doctor before taking THIOBLIS 4 TABLET.
What if I skip a dose of THIOBLIS 4 TABLET?
If you miss a dose of THIOBLIS 4 TABLET, you should take it as soon as possible. If it’s time for the next dose, do not take the missed dose. Continue the management as scheduled by your doctor.
References
1. KD Tripathi. Skeletal Muscle Relaxants. Essentials of medical pharmacology. Eighth Edition. 2019. Page –383-384.
2. Marco Gervasi, Davide Sisti, Piero Benelli, Eneko Fernández-Peña, Cinzia Calcabrini, Marco B.L. Rocchi, Luigi Lanata, Michela Bagnasco, Andrea Tonti, Stocchi Vilberto, and Piero Sestili. The effect of topical thiocolchicoside in preventing and reducing the increase of muscle tone, stiffness, and soreness. [Accessed on 6th July 2022] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5627858/
3. A.R Umarkar, S.R Bavaskar & P.N.Yewale. Thiocolchicoside as Muscle Relaxant: A Review. [Revised in September 2011] [Accessed on 6th July 2022] http://www.ijpbsonline.com/uploads/1/2/1/8/12183777/364-371.pdf
4. Iasis Pharma Hellas s.a. Thiocolchicoside [Revised in October 2014] [Accessed on 6th July 2022] https://iasispharma.com/wp-content/uploads/pdf/RELIEF_PIL_ENG.pdf
5. European Medical Agency. Thiocolchicoside. [Revised on November 2013] [Accessed on] https://www.ema.europa.eu/en/documents/referral/thiocolchicoside-article-31-referral-annex-iii_en.pdf
6. Thiocolchicoside. Pubchem. [Revised in July 2022] [Accessed on 6th July 2022] https://pubchem.ncbi.nlm.nih.gov/compound/Thiocolchicoside#section=Associated-Disorders-and-Diseases
7. Thiocolchicoside. Clevelandclinic. [Revised in March 2021] [Accessed on 6th July 2022] https://my.clevelandclinic.org/health/diseases/15466-muscle-spasms
Author Details
The contents of this website are for informational purposes only and not intended to be a substitute for professional medical advice, diagnosis, or treatment. Please seek the advice of a physician or other qualified health provider with any questions you may have regarding a medical condition. Do not disregard professional medical advice or delay in seeking it because of something you have read on this website.
