TENEMERZ 20mg Tablet 10's

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Introduction About TENEMERZ 20MG TABLET

TENEMERZ 20MG TABLET belongs to the class of DPP-4 inhibitors, used to manage type 2 diabetes mellitus. It works by increasing insulin production and reducing sugar levels in the blood.

TENEMERZ 20MG TABLET regulates blood sugar levels, improves insulin response and easy-to-take oral medication.

Take one tablet daily with or without food, as prescribed by your doctor. Do not exceed the recommended dose.

TENEMERZ 20MG TABLET is not recommended for type 1 diabetes or diabetic ketoacidosis. Inform your doctor if you have kidney or liver issues. Pregnant or breastfeeding women should consult a healthcare provider before taking TENEMERZ 20MG TABLET.

The common side effects include headache, sore throat, and mild gastrointestinal issues. Consult your physician if symptoms persist or worsen.

Uses Of TENEMERZ 20MG TABLET

  • Used to manage Type II diabetes mellitus

Benefits of TENEMERZ 20MG TABLET

1. Regulates blood sugar levels:

  • TENEMERZ 20MG TABLET helps maintain optimal blood glucose levels, particularly in patients with Type 2 Diabetes
  • It reduces post-meal blood sugar spikes and supports steady sugar control throughout the day

2. Improves insulin response:

  • By enhancing the action of incretin hormones, TENEMERZ 20MG TABLET boosts the body’s natural insulin production in response to meals and reduces excessive glucose release from the liver, improving overall insulin efficiency

3. Easy-to-take oral medication:

  • This tablet is taken orally, once daily, with or without food, offering a hassle-free alternative to injections
  • It’s simplicity increases management adherence and long-term diabetes control

How TENEMERZ 20MG TABLET Works

How it helps in diabetes management:

1. Enhancing incretin hormone activity:

  • Incretins are natural hormones that help regulate blood sugar
  • TENEMERZ 20MG TABLET increases the levels of these hormones, which stimulate insulin release after meals, decrease glucose production in the liver, help lower blood sugar levels more effectively

2. Controlling post-meal glucose spikes:

  • One of the major challenges in diabetes is managing blood sugar after eating. TENEMERZ 20MG TABLET targets this phase specifically, helping to manage sudden sugar spikes

3. Reducing the risk of hypoglycemia:

  • Unlike some other diabetes medications, TENEMERZ 20MG TABLET does not cause significant drops in blood sugar when used alone, making it safer and well-tolerated for most patients

4. Supporting long-term glycemic control

  • Regular use of TENEMERZ 20MG TABLET, as prescribed by a doctor, helps in maintaining HbA1c levels, a key marker of long-term blood glucose control

How to use TENEMERZ 20MG TABLET

Recommended dosage of TENEMERZ 20MG TABLET:

  • One tablet (20 mg) of TENEMERZ 20MG TABLET once daily
  • It can be taken with or without food
  • It should be taken at the same time each day for best results

Instructions for use for TENEMERZ 20MG TABLET:

  • Take one tablet once daily, or as directed by your doctor
  • Swallow the tablet whole with a glass of water. Do not crush, chew, or break the tablet
  • It can be taken with or without food, but try to take it at the same time every day to maintain a consistent level in your bloodstream
  • It should be preferably taken at the same time daily (e.g., morning with breakfast)

What if I forgot to take TENEMERZ 20MG TABLET

  • Take the missed dose as soon as you remember
  • If it is almost time for your next scheduled dose, skip the missed dose
  • Do not double up to catch up for the missed dose

Side Effects Of TENEMERZ 20MG TABLET

Common side effects of TENEMERZ 20MG TABLET

  • headache
  • sore throat
  • mild gastrointestinal issues

How To Manage Side Effects

Headache

  • Drink plenty of water throughout the day
  • Maintain balanced meals with proteins, healthy fats, and fiber
  • Aim for 7-8 hours of restful sleep

Sore Throat

  • Gargle with warm water or a saline solution after inhalation to remove residual medication
  • Drink plenty of water to soothe the throat and keep it moist
  • Warm herbal teas with ginger, chamomile, or licorice may also provide relief

Stomach Discomfort

  • Include fiber-rich foods like vegetables, whole grains, and fruits to aid digestion
  • Avoid spicy, greasy, or processed foods, which can aggravate stomach discomfort
  • Gentle physical activity like walking after meals can help improve digestion and reduce bloating

Warning & Precautions

Pregnancy

Monitoring required

Animal studies have not demonstrated significant teratogenic effects. However, due to the absence of comprehensive human studies, Teneligliptin should only be used during pregnancy if the potential benefits justify the potential risks to the fetus.

Breastfeeding

Contraindicated

Animal studies indicate that Teneligliptin is excreted in milk. The presence of Teneligliptin in human breast milk is unknown, and its effects on the nursing infant have not been studied. Therefore, breastfeeding is not recommended during treatment with Teneligliptin.

Driving and Using Machines

Use with Caution

Do not drive or operate any machines if you feel dizzy after taking TENEMERZ 20MG TABLET.

Alcohol

Consult your doctor

Avoid consumption of alcohol while taking TENEMERZ 20MG TABLET as it may increase the risks of side effects.

Liver

Use with Caution

TENEMERZ 20MG TABLET should be used with caution in patients with severe liver diseases.

Allergy

Contraindicated

Do not take TENEMERZ 20MG TABLET if you are allergic to Teneligliptin or any of the other ingredients of this medicine.

Heart Disease

Use with Caution

TENEMERZ 20MG TABLET should be used with caution in patients with heart problems (like heart failure or slow heartbeat).

Use In Pediatrics

Consult your doctor

There is no proper information regarding the use of TENEMERZ 20MG TABLET in children and in adolescents (below 18 years).

Use In Geriatrics

Use with Caution

TENEMERZ 20MG TABLET should be used with caution in elderly patients. Therefore, consult your doctor before taking the medicine. Proper dose adjustments and careful monitoring are required in such patients.

Other Warnings for TENEMERZ 20MG TABLET

Before taking TENEMERZ 20MG TABLET, inform your doctor if you:

  • have pituitary insufficiency or adrenal insufficiency
  • are malnourished, starved, on an irregular diet, or feeling weak
  • perform extreme muscle exercises
  • have a history of abdominal operation or intestinal obstruction
  • have hypokalaemia (low blood potassium levels)

Who should not take [GBNKEYWORD

TENEMERZ 20MG TABLET is not recommended for use if you:

  • have severe ketosis (increased levels of ketone bodies in the blood)
  • have diabetic coma or precoma
  • have type I diabetes mellitus
  • have serious traumatic injury

Diet and Lifestyle Advice

Best foods to eat while TENEMERZ 20MG TABLET:

  • Brown rice, quinoa, whole wheat bread, oats
  • Lentils, chickpeas, kidney beans
  • Spinach, kale, broccoli, carrots
  • Apples, pears, oranges, berries
  • Eggs, chicken, fish, tofu & paneer
  • Broccoli, cauliflower, cabbage

Exercise tips to enhance the effectiveness of TENEMERZ 20MG TABLET:

  • Cardiovascular (Aerobic) Exercises
  • Strength Training – Builds Muscle & Burns Fat
  • Flexibility & Balance Exercises – Manages Diabetes-Related Complications
  • High-Intensity Interval Training (HIIT) – Quick & Effective

Foods & drinks to avoid while on TENEMERZ 20MG TABLET:

  • Sugary foods & high-carb processed foods
  • Fried & fatty foods
  • Alcohol & caffeinated drinks
  • High-sodium foods
  • Dairy products with added sugar & artificial sweeteners

How to balance your diet to manage blood sugar spikes:

  • Prioritize low-glycemic index (GI) foods
  • Eat more protein with every meal
  • Add healthy fats for better blood sugar control
  • Control carbohydrate intake
  • Stay hydrated & avoid sugary drinks
  • Eat at regular intervals
  • Plan a balanced plate (the diabetes plate method)

Drug - Drug interaction

Drug/Drug Class

Interaction Type

Possible Effect

Recommendation

Sulfonylureas (e.g., Glimepiride)

Additive Hypoglycemic Effect

May increase risk of low blood sugar (hypoglycemia)

Monitor blood sugar; dosage adjustment may be needed

Metformin

Complementary Action

Safe, often prescribed together for improved glycemic control

Usually co-administered

Insulin

Additive Hypoglycemic Effect

Risk of hypoglycemia when used with Teneligliptin

Close monitoring and possible dose reduction

Rifampicin (antibiotic)

Enzyme Inducer

May reduce effectiveness of TENEMERZ 20MG TABLET by increasing metabolism

Monitor blood sugar levels

Corticosteroids (e.g., Prednisone)

Antagonistic Effect

May raise blood sugar, reducing TENEMERZ 20MG TABLET effectiveness

Monitor glucose closely

Thiazide diuretics

Hyperglycemic Potential

Can increase blood glucose levels

Monitor and adjust therapy as needed

Beta-blockers (e.g., Atenolol)

Masking Effect

May mask symptoms of hypoglycemia (e.g., rapid heartbeat)

Use with caution; patient education needed

Alcohol

Unpredictable Effect

May enhance or reduce blood sugar unpredictably

Limit or avoid alcohol

Synopsis

Drug :   Teneligliptin
Pharmacological Category :   Dipeptidyl Peptidase-4 Inhibitors
Therapeutic Indication :   Type II Diabetes mellitus                     
Dosage Forms :   Tablet

More Information

How TENEMERZ 20MG TABLET compares to other DPP-4 inhibitors:

Feature

TENEMERZ 20MG TABLET (Teneligliptin)

Sitagliptin

Saxagliptin

Linagliptin

Dosage

20 mg once daily

100 mg once daily

5 mg once daily

5 mg once daily

Half-Life

~24 hours

~12 hours

~2.5 hours

~12 hours

Renal Adjustment Needed?

No (mild to moderate CKD)

Yes

Yes

No

Liver Adjustment Needed?

Use with caution

Generally safe

Safe

Safe

Weight Neutral?

Yes

Yes

Yes

Yes

Hypoglycemia Risk (Monotherapy)

Low

Low

Low

Low

Combination Therapy Use

Metformin, sulfonylureas, insulin

Same

Same

Same

Cost (India)

Lower (more affordable)

Higher

Higher

Higher

Availability in India

Widely available

Widely available

Limited

Limited

 

Side effects you should not ignore:

Symptom

What it may indicate

What to do

Severe abdominal pain

Possible pancreatitis

Stop medication and consult a doctor right away

Persistent sore throat or fever

Possible infection or low white blood cell count

Get medical advice promptly

Skin rash, itching, or swelling

Allergic reaction or hypersensitivity

Discontinue use and seek emergency care

Dizziness or fainting

Blood sugar fluctuation or low blood pressure

Monitor sugar levels, consult your doctor

Shortness of breath or chest tightness

Possible cardiac or respiratory reaction

Seek urgent medical attention

Yellowing of eyes or skin

Liver dysfunction

Stop taking and get liver function tests done

Unusual fatigue or weakness

Possible lactic acidosis (especially with metformin)

Immediate evaluation needed

 

Interaction warnings with common foods:

Item

Effect

Advice

High-sugar foods

Counteracts medication effect

Follow a diabetes-friendly diet

Grapefruit juice

No known major interaction with Teneligliptin

Can be consumed, unless advised otherwise

Caffeine

May worsen headache side effects in sensitive users

Consume in moderation

 

What makes TENEMERZ 20MG TABLET cheaper or cost-effective?

1. Indian-Manufactured Generic:

  • TENEMERZ 20MG TABLET is manufactured by Indian pharmaceutical companies, which lowers production and distribution costs

2. No Patent-Related Premium:

  • Teneligliptin’s patent has expired or is not enforced in several countries, allowing multiple brands to market it
  • The absence of patent restrictions results in healthy competition and price reduction

3. Single-Ingredient Formulation:

  • Unlike combination pills (e.g., with metformin), TENEMERZ 20MG TABLET contains only Teneligliptin, reducing manufacturing complexity and cost

4. Fewer Monitoring Requirements:

  • Since TENEMERZ 20MG TABLET does not require renal dose adjustment in most cases, it reduces the need for expensive routine lab monitoring

5. Widely Available in India:

  • Approved and marketed in India since 2013, Teneligliptin has widespread availability across urban and rural regions, keeping prices competitive

Is there a cheaper alternative to TENEMERZ 20MG TABLET? Or You may also like:

Type 2 Diabetes Mellitus:

Type 2 Diabetes Mellitus (T2DM) is a chronic metabolic disorder characterized by high blood sugar levels due to insulin resistance and/or reduced insulin production. If left untreated, it can lead to serious complications like heart disease, kidney damage, and nerve disorders.

  • Insulin resistance - Body cells do not respond effectively to insulin
  • Pancreatic dysfunction - Reduced insulin production over time
  • Genetics & family history - Higher risk if a parent or sibling has diabetes
  • Unhealthy lifestyle - Poor diet, obesity, and lack of exercise contribute
  • Hormonal imbalances – Conditions like PCOS and thyroid disorders can increase risk

Common symptoms of Type 2 Diabetes:

  • Excessive thirst and frequent urination
  • Unexplained weight loss or weight gain
  • Fatigue and low energy
  • Blurred vision
  • Slow wound healing and frequent infections

How type 2 Diabetes Progresses:

1. Early Stage: Mild insulin resistance, high fasting glucose levels

2. Intermediate Stage: Increased insulin resistance, post-meal sugar spikes

3. Advanced Stage: Significant insulin deficiency, requiring medications like TENEMERZ 20MG TABLET or insulin therapy

FAQs About TENEMERZ 20MG TABLET

Q: What is TENEMERZ 20MG TABLET used for?

A: TENEMERZ 20MG TABLET contains Teneligliptin which is used to manage type II diabetes (high blood sugar levels) in adults, that cannot be controlled by diet and exercise alone. Your doctor will decide the correct dose and duration of therapy for you depending upon your age, body weight and disease condition.

Q: Can I take TENEMERZ 20MG TABLET with other diabetes medications?

A: Yes, TENEMERZ 20MG TABLET but only under medical supervision to avoid hypoglycemia.

Q: Can I drink alcohol while on TENEMERZ 20MG TABLET?

A: It is not recommended to consume alcohol while taking TENEMERZ 20MG TABLET, especially if you are being managed for type 2 diabetes.

Q: Is TENEMERZ 20MG TABLET safe to use in pregnancy?

A: TENEMERZ 20MG TABLET should be used in pregnant women only if prescribed by the physician. Your doctor may prescribe TENEMERZ 20MG TABLET for you after evaluating the risks and benefit ratio.

Q: What precautions do I need to follow while taking TENEMERZ 20MG TABLET?

A: Before taking TENEMERZ 20MG TABLET, inform your doctor if you have any liver or heart problems. You must also inform your doctor if you have hormonal problems, stomach problems (surgery in the gut) or if you are malnourished. TENEMERZ 20MG TABLET is not suitable for use in patients with type I diabetes mellitus.

Q: Can I take medication for high blood pressure along with TENEMERZ 20MG TABLET?

A: No. It is not advisable to take medicines to control blood pressure while taking TENEMERZ 20MG TABLET without consulting your doctor.

Q: What should I do if I experience low blood sugar after taking TENEMERZ 20MG TABLET?

A: Low blood sugar is a common side effect of taking TENEMERZ 20MG TABLET. Try to have sugar rich food items such as fruit juice, glucose tablets or gel, soft drinks, honey, or sugary candy. Check your blood sugar after 10 minutes. If not gained optimum level, take another sugary snack, or drink, and check the blood sugar again. In case of persistent low blood sugar levels, consult your doctor immediately.

Q: How does TENEMERZ 20MG TABLET work in diabetes management?

A: TENEMERZ 20MG TABLET contains Teneligliptin, which belongs to a class of medications called DPP-4 inhibitors (dipeptidyl peptidase-4 inhibitors). It helps manage type 2 diabetes mellitus by improving blood sugar control.

Q: Can TENEMERZ 20MG TABLET cause dizziness?

A: Yes. Dizziness is a common side effect of using TENEMERZ 20MG TABLET In case you experience dizziness, lie down until it passes, then get up slowly and carefully. Get adequate rest. Drink plenty of water and other fluids. Avoid coffee, cigarettes, and alcohol. Do not drive or use machinery to avoid accidents.

Q: Can TENEMERZ 20MG TABLET be taken with insulin?

A: Co-administration of TENEMERZ 20MG TABLET with insulin is considered risky as they are increased chances of hypoglycemia (decreased blood sugar levels).

Q: How to take TENEMERZ 20MG TABLET?

A: You must take TENEMERZ 20MG TABLET as advised by your physician. Try to take this medicine preferably after meals and swallow it with a glass of water. Do not crush or chew the medicine.

Q: How much TENEMERZ 20MG TABLET should I take?

A: TENEMERZ 20MG TABLET should be used only under medical supervision. Your doctor will decide the correct dose and duration of therapy for you depending upon your age, body condition and severity of the disease condition.

References

1. Joseph T. DiPiro, Robert L. Talbert, Gary C. Yee, Gary R. Matzke, Barbara G. Wells, L. Michael Posey. Diabetes Mellitus. Pharmacotherapy- A Pathophysiologic Approach. Eighth edition. Page- 1263, 1264.

2. Mitra, A., & Ray, S. Evaluation of the Safety and Efficacy of Teneligliptin at a Higher Dose in Indian Type 2 Diabetes Patients: A Retrospective Analysis. NIH National Library of Medicine, National center for biotechnology information. PubMed Central. January 2020. [Accessed on 4th June 2025]

3. Torrent Pharmaceutical Ltd. Teneligliptin. [Revised in April 2021] [Accessed on 4th June 2025]

4. Mitsubishi Tanabe Pharma Factory Ltd. Teneligliptin. [Revised in April 2020] [Accessed on 4th June 2025]

Author Details

Written By Dr. Karthikeyan Rajagopal - M.Pharm (Pharmacology)
Reviewed By Dr. Sankara Babu Gorle - MBBS, MD(Pharmacology) View profile
Last updated on 04 Jun 2025 | 03:54 PM(IST)
    Net Qty
    1 N
    Shelf Life
    720 days
    Item Weight
    17.5 g
    Ingredient
    Teneligliptin 20 mg
    Hsn Code
    30049099
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