Introduction About TELEKAST T TABLET

TELEKAST T TABLET is a combination of Montelukast and Theophylline which belongs to the group of medicines called Leukotriene receptor antagonists and Xanthines respectively. TELEKAST T TABLET is used to manage bronchial asthma.

Asthma is a condition in which a person's airways becomes inflamed, narrow, swell and produce extra mucus, which makes it difficult for a person to breathe which is generally characterized by symptoms such as shortness of breath, chest pain, wheezing (whistling sound while breathing) and sleeplessness.

Before taking TELEKAST T TABLET, inform your doctor if you are asthmatic, have worsening chest symptoms such as breathlessness or cough, stomach ulcer, cystic fibrosis (a life-threatening disorder that damages lungs and digestive system), seizures, fits or convulsions, have a viral infection or have heart, kidney or liver problems.  

Consult your doctor before taking TELEKAST T TABLET if you are pregnant or planning to have a baby or a breastfeeding woman. TELEKAST T TABLET is not recommended for use in children and adolescents (aged below 15 years). It should be used with caution in patients with elderly patients. Consult your doctor before taking this medicine.

The most common symptoms of taking TELEKAST T TABLET are abdominal pain, headache, diarrhoea, nausea, vomiting and fever. Consult your doctor if any of the side effects get worse. 

Uses Of TELEKAST T TABLET

• Manage bronchial asthma  

How TELEKAST T TABLET Works

TELEKAST T TABLET helps in managing the symptoms of asthma, where montelukast blocks leukotriene (a chemical messenger) that results in the reduction of inflammation of the airways and theophylline (a xanthine derivative) that acts by relaxing the muscles of the airways that results in easier breathing by managing the symptoms of asthma.

How to use TELEKAST T TABLET

Take TELEKAST T TABLET as advised by your physician. Swallow TELEKAST T TABLET with a glass of water and do not chew or crush the medicine. Your doctor will decide the correct dose and duration for you depending upon your age, body weight and disease condition.

Side Effects Of TELEKAST T TABLET

How To Manage Side Effects

Diarrhoea:

Drink lot of fluids such as water to keep yourself hydrated. Try to avoid taking any medicine on your own to manage diarrhoea and consult your doctor if the symptom gets worse.

Dizziness:

Lie down until the dizziness passes away and then move slowly and carefully. Take plenty amount of rest and drink plenty of fluids. Consult and inform your doctor if the symptom does not improve.

Headache:

Apply hot or cold-water bag on your head. Try taking rest in a quiet and dark room. Drink tea or coffee. Consult and inform your doctor if the symptom does not improve.

Nausea and vomiting:

Try to take TELEKAST T TABLET with or just after a meal or a snack. Stick to simple meals. Avoid eating oil-rich, fried or spicy food. Consult your doctor if the symptom gets worse.

Warning & Precautions

Pregnancy

TELEKAST T TABLET should be used during pregnancy only if considered clearly necessary. Consult your doctor before taking TELEKAST T TABLET.  

Breastfeeding

TELEKAST T TABLET should be used in breast-feeding women only if considered clearly necessary as this medicine is secreted in breast milk and cause irritability to the infant while breast-feeding. Consult your doctor before taking TELEKAST T TABLET.      

Driving and Using Machines

TELEKAST T TABLET might cause dizziness or drowsiness. If you experience these side effects, try to avoid driving or operating heavy machines. Consult your doctor before taking TELEKAST T TABLET.

Alcohol

Avoid consumption of alcohol while taking TELEKAST T TABLET since it may alter the effect of the medicine. Consult your doctor before taking TELEKAST T TABLET.   

Kidney

TELEKAST T TABLET should be used with caution in patients with kidney problems. Consult your doctor before taking TELEKAST T TABLET.  

Liver

TELEKAST T TABLET should be used with caution in patients with liver problems. Consult your doctor before taking TELEKAST T TABLET.

Allergy

TELEKAST T TABLET is not recommended for use if you are allergic to Montelukast Theophylline, or aminophylline.

Lungs

TELEKAST T TABLET should be used with caution in patients with asthma or breathing problems. Consult your doctor before taking TELEKAST T TABLET.   

Heart Disease

TELEKAST T TABLET should be used with caution in patients with heart problems such as irregular heartbeat, high blood pressure or other heart problems. Consult your doctor before taking TELEKAST T TABLET.

Interactions

A. Drug-Drug Interactions:

Before taking TELEKAST T TABLET, inform your doctor, if you are taking any of the following medicines:

• acetylsalicylic acid (used for mild to moderate pain and to manage fever)
• anti-inflammatory medicines (used to relieve pain, reduce inflammation and fever) Ex. ibuprofen, naproxen, diclofenac
• carbamazepine, phenobarbital, phenytoin (used for the management of epilepsy)
• rifampicin or isoniazid (used to manage tuberculosis)
• gemfibrozil (used for the management of high cholesterol)
• certain other medicines to manage asthma or breathing conditions that contain aminophylline, salbutamol, terbutaline or salmeterol
• steroids (used for allergic red, itchy skin and painful joints and muscles) Ex. prednisolone, betamethasone, dexamethasone.
• diuretics (medicine used to increase urine production) Ex. aldactone, bumetanide, torsemide
• oral contraceptives (medicines used to manage pregnancy) Ex. estrogen and progestin
• st.john’s wort (herbal medicine used for depression)
• aminoglutethimide, methotrexate or lomustine (medicine used to manage cancer)
• medicines used to manage high blood pressure and other heart problems (Ex. adenosine, diltiazem, isoprenaline, mexiletine, propafenone, propranolol, verapamil or beta blockers such as acebutolol, atenolol, bisoprolol)
• regadenoson or dipyridamole (medicines used to manage heart problems)
• medicine used to manage diseased blood vessels Ex. pentoxifylline
• medicines used as a sedative or to manage anxiety such as benzodiazepine (Ex. alprazolam, chlordiazepoxide, clorazepate)
• medicine used to manage herpes simplex infection due to herpes virus Ex. aciclovir
• medicine used to manage gout Ex. sulphinpyrazone or allopurinol
• medicine used to manage problems associated with thyroid glands Ex. carbimazole
• cimetidine or nizatidine (medicines used to manage stomach ulcers, indigestion or heartburn)
• ciprofloxacin, clarithromycin, erythromycin, enoxacin (medicines used to manage bacterial infections)
• fluconazole (medicine used to manage fungal infections)
• ritonavir (medicine used to manage HIV)
• interferons (medicines used to manage conditions such as herpes, cancer, leukemia (white blood cancer) or hepatitis (inflammation of liver) Ex. interferon alfa-2a, interferon alfa-2b
• thiabendazole (medicines used to manage infections caused by worms such as threadworms)
• fluvoxamine or lithium (medicines used to manage depression)
• doxapram (medicines used to stimulate breathing)
• disulfiram (medicines used to manage alcoholism)
• a cough medicine or decongestant containing ephedrine (medicine used to manage nasal congestion, breathing problems)

Overdosage:

If you or anyone else accidentally takes too much of TELEKAST T TABLET, consult your doctor immediately or visit the nearby hospital. Overdosage symptoms of TELEKAST T TABLET are abdominal pain, sleepiness, thirst, headache, vomiting, hyperactivity, stomach pain, vomiting blood, fast or irregular heartbeat, low blood pressure, feel very restless, experience overactive reflexes or unusual muscle stiffness, have a fit or even go into a coma.

Synopsis

More Information

• Keep the medicine out of reach of children
• Store TELEKAST T TABLET at room temperature

FAQs About TELEKAST T TABLET

What is TELEKAST T TABLET used for?

TELEKAST T TABLET is used to manage the symptoms of asthma which is a condition in which a person's airways becomes inflamed, narrow, swell and produce extra mucus resulting in difficulty while breathing which is generally characterized by symptoms such as shortness of breath, chest pain, wheezing (whistling sound while breathing) and sleeplessness.

Who should avoid taking TELEKAST T TABLET?

TELEKAST T TABLET is not recommended for use in patients who have porphyria (a rare disease of the blood pigments) and those who are allergic to montelukast, theophylline or aminophylline. Consult your doctor before taking TELEKAST T TABLET.   

What are the common side effects of TELEKAST T TABLET?

The most common side effects of taking TELEKAST T TABLET are abdominal pain, headache, diarrhea, nausea, vomiting, fever and rash. Consult your doctor if any of the side effects get worse.   

Is it safe to drive after taking TELEKAST T TABLET?

TELEKAST T TABLET might cause dizziness and drowsiness. If you experience these side effects, try to avoid driving or operating heavy machines. Consult your doctor before taking TELEKAST T TABLET.

What happens if you take more TELEKAST T TABLET than your required dose?

If you or anyone else accidentally takes too much of TELEKAST T TABLET, consult your doctor immediately or visit the nearby hospital. Overdose symptoms of TELEKAST T TABLET are abdominal pain, sleepiness, thirst, headache, vomiting, hyperactivity, stomach pain, vomiting blood, fast or irregular heartbeat, low blood pressure, feel very restless, experience overactive reflexes or unusual muscle stiffness, have a fit or even go into a coma.

References

1. KD. Tripathi. Drugs for Cough and Bronchial Asthma. Essentials of medical pharmacology. Seventh edition. 2013. Page – 224 & 228

2. Organon and Co. Montelukast Post-marketing Comparative Study With Theophylline added to Inhaled Corticosteroid (0476-396). NIH U.S. National Library of Medicine ClinicalTrials.gov. [Revised in February 2022] [Accessed on 31st May 2022] https://clinicaltrials.gov/ct2/show/NCT00756418

3. Harrison R. Wermuth; Talel Badri; Veronica Takov. Montelukast. NIH National Library of Medicine, National center for biotechnology information. April 2022 [Accessed on 31st May 2022] https://www.ncbi.nlm.nih.gov/books/NBK459301/

4. Talha N. Jilani; Charles V. Preuss; Sandeep Sharma. Theophylline. NIH National Library of Medicine, National center for biotechnology information. May 2022 [Accessed on 31st May 2022] https://www.ncbi.nlm.nih.gov/books/NBK519024/

5. Guillermo Sánchez, and Diana Buitrago. Effect of Montelukast 10 mg in Elderly Patients with Mild and Moderate Asthma Compared with Young Adults. Results of a Cohort Study. NIH National Library of Medicine, National center for biotechnology information. November 2018 [Accessed on 31st May 2022] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6425064/

6. Ludmila N Bakhireva , Kenneth Lyons Jones, Michael Schatz, Hillary S Klonoff-Cohen, Diana Johnson, Donald J Slymen, Christina D Chambers, Organization of Teratology Information Specialists Collaborative Research Group. Safety of leukotriene receptor antagonists in pregnancy. NIH National Library of Medicine, National center for biotechnology information. PubMed.gov. March 2007 [Accessed on 31st May 2022] https://pubmed.ncbi.nlm.nih.gov/17336611/

7. M C Frederiksen, T I Ruo, M J Chow, A J Atkinson Jr. Theophylline pharmacokinetics in pregnancy. Safety of leukotriene receptor antagonists in pregnancy. NIH National Library of Medicine, National center for biotechnology information. PubMed.gov. September 1986 [Accessed on 31st May 2022] ttps://pubmed.ncbi.nlm.nih.gov/3742937/

8. Amarox Limited. Electronic medicines compendium (EMC). [Revised in November 2020] [Accessed on 31st May 2022] https://www.medicines.org.uk/emc/files/pil.13555.pdf

9. Bard Pharmaceuticals Limited. Electronic medicines compendium (EMC). [Revised in January 2019] [Accessed on 31st May 2022] https://www.medicines.org.uk/emc/files/pil.7717.pdf

Useful Diagnostic Tests

• Pulmonary function test