Introduction About TEGNECT M 20/500MG TABLET

TEGNECT M 20/500MG TABLET is a medication used for managing type 2 diabetes. It helps regulate blood sugar levels effectively.

TEGNECT M 20/500MG TABLET controls blood sugar levels in type 2 diabetes patients, manages diabetes-related complications and improves insulin sensitivity.

Take TEGNECT M 20/500MG TABLET as prescribed by your doctor. Usually taken once daily with or without food.

Before taking TEGNECT M 20/500MG TABLET inform your doctor if you have any liver, kidney or heart problems. You must also inform your doctor if you have low potassium levels in blood or are severely dehydrated due to excessive vomiting or diarrhea recently.

The most common side effects of taking TEGNECT M 20/500MG TABLET are nausea, stomach discomfort and low blood sugar (if combined with other diabetes medicines). Consult your doctor if any of the above side effects bother you.

Uses Of TEGNECT M 20/500MG TABLET

• Used to manage Type II diabetes

Benefits of TEGNECT M 20/500MG TABLET

1. Controls blood sugar levels in type 2 diabetes patients:

• TEGNECT M 20/500MG TABLET contains Teneligliptin and Metformin which work together to lower high blood glucose levels
• It enhances insulin secretion from the pancreas and reduces glucose production in the liver
• Helps maintain steady blood sugar levels throughout the day and after meals

2. Manages diabetes-related complications:

• By keeping blood sugar under control, TEGNECT M 20/500MG TABLET helps to manage long-term complications like:
• Nerve damage (neuropathy)
• Kidney problems (nephropathy)
• Eye diseases (retinopathy)
• Heart conditions (cardiovascular risks)
• Regular use as prescribed by a doctor can help improve overall health outcomes for diabetes patients

3. Improves insulin sensitivity:

• Metformin in TEGNECT M 20/500MG TABLET enhances the body's response to insulin, making it more effective
• Reduces insulin resistance, ensuring better glucose uptake by muscles and tissues
• Supports weight management in diabetes patients by managing excess fat accumulation

How TEGNECT M 20/500MG TABLET Works

TEGNECT M 20/500MG TABLET contains Metformin and Teneligliptin. Metformin works by lowering glucose production in the liver, delaying glucose absorption from intestines and increasing the body’s sensitivity to insulin. Teneligliptin is a dipeptidyl peptidase-4 inhibitor which works by increasing the release of insulin from pancreas and decreasing the hormones that raise blood sugar levels. This reduces both fasting and post-meal sugar levels. Together, they provide better control of blood sugar.

How to use TEGNECT M 20/500MG TABLET

How to take TEGNECT M 20/500MG TABLET correctly?

• Take TEGNECT M 20/500MG TABLET with a meal or immediately after eating
• Swallow whole, do not crush, chew, or break the tablet
• Take the exact dose prescribed by your doctor, do not increase or decrease the dose on your own
• Stick to a routine: Take it at the same time daily for consistent blood sugar control
• Follow a balanced diet, exercise regularly, and manage stress to improve diabetes control

TEGNECT M 20/500MG TABLET dosage instructions:

• The usual dose is one tablet once or twice daily with meals
• The dosage may vary depending on blood sugar levels, medical history, and other medications
• Do not self-adjust the dosage without consulting your doctor

What if I forgot to take TEGNECT M 20/500MG TABLET

• If you realize you missed a dose within a few hours, take it immediately with food
• If it is close to your next scheduled dose, skip the missed dose and continue with your regular routine
• Do not take a double dose to make up for the missed one, as this can increase the risk of low blood sugar (hypoglycemia)

Overdose

If you or anyone else accidentally took more of TEGNECT M 20/500MG TABLET, consult your doctor immediately or visit the nearby hospital. Symptoms of overdose are feeling cold, severe nausea or vomiting, stomach pain, unexplained weight loss, muscular cramps and fast breathing.

Side Effects Of TEGNECT M 20/500MG TABLET

Common side effects of TEGNECT M 20/500MG TABLET:

• nausea
• stomach discomfort
• low blood sugar (if combined with other diabetes medicines)

When to consult a doctor?

• serious allergic reaction (hives, swelling of the face, lips, tongue or throat causing difficulty in breathing or swallowing)
• severe skin rashes with redness and blistering of the skin
• signs of lactic acidosis (cold hands or feet, dizziness or light-headedness, slow or irregular heartbeat, weakness or tiredness, unusual muscle pain, trouble breathing, sleepiness or drowsiness, stomach pains, nausea or vomiting)
• signs of liver damage (tiredness, loss of appetite, weight loss, with or without yellowing of the skin or whites of the eyes)

How To Manage Side Effects

Nausea And Vomiting

• Always take TEGNECT M 20/500MG TABLET with a meal or immediately after eating
• Drink plenty of water throughout the day to manage dehydration
• Instead of large meals, try eating small, balanced meals throughout the day
• Ginger tea, ginger candies, or peppermint tea can help settle the stomach and reduce nausea
• Stay upright for at least 30 minutes after taking the medication to manage acid reflux and nausea

Stomach Discomfort

• Include fiber-rich foods like vegetables, whole grains, and fruits to aid digestion
• Avoid spicy, greasy, or processed foods, which can aggravate stomach discomfort
• Gentle physical activity like walking after meals can help improve digestion and reduce bloating

Warning & Precautions

Pregnancy

Consult your doctor

Human studies on Teneligliptin's safety during pregnancy are lacking. Animal studies have not shown harm to the fetus, but these results do not always predict human responses. Metformin’s long-term effects on offspring are still under investigation. Hence TEGNECT M 20/500MG TABLET should only be used during pregnancy if the potential benefit justifies the potential risk to the fetus.

Breastfeeding

Contraindicated

Animal studies indicate Teneligliptin may transfer into milk and cause caution. Metformin is present in human breast milk in low amounts. Hence TEGNECT M 20/500MG TABLET should be avoided by breastfeeding mothers.

Driving and Using Machines

Use with Caution

Do not drive or operate any machines if you feel dizzy after taking TEGNECT M 20/500MG TABLET.

Alcohol

Consult your doctor

Avoid consumption of alcohol while taking TEGNECT M 20/500MG TABLET as it may increase the risk of unwanted side effects.

Kidney

Contraindicated

TEGNECT M 20/500MG TABLET is not recommended for use in patients with severely reduced kidney functions.

Liver

Consult your doctor

TEGNECT M 20/500MG TABLET is not recommended for use in patients with severe liver problems. It should be used with caution in patients with gall stones.

Allergy

Contraindicated

Do not take TEGNECT M 20/500MG TABLET if you are allergic to Metformin or Teneligliptin or any other ingredients of this medicine.

Lungs

Contraindicated

TEGNECT M 20/500MG TABLET is not recommended for use in patients with severe infections of the lungs or respiratory tract.

Heart Disease

Contraindicated

TEGNECT M 20/500MG TABLET is not recommended for use in patients with severe heart problems (such as acute heart failure, recent heart attack, arrythmia, prolonged QT interval).

Use In Pediatrics

Consult your doctor

The safety and effectiveness of TEGNECT M 20/500MG TABLET have not been established in infants, children and adolescents (aged below 18 years).

Use In Geriatrics

Consult your doctor

The safety and effectiveness of TEGNECT M 20/500MG TABLET have not been established in elderly patients (aged 65 years or above).

Other Warnings for TEGNECT M 20/500MG TABLET

Before taking TEGNECT M 20/500MG TABLET, inform your doctor if you:

• have pituitary insufficiency or adrenal insufficiency
• are malnourished, starved, on an irregular diet, or feeling weak
• perform extreme muscle exercises
• have a history of abdominal operation or intestinal obstruction
• have hypokalaemia
• have type I diabetes mellitus
• have severe traumatic conditions

Who should not take [GBNKEYWORD

TEGNECT M 20/500MG TABLET is not recommended for use if you:

• have severe, uncontrollable diabetes
• have lactic acidosis or ketoacidosis
• are dehydrated (due to drinking less fluid or had severe vomiting or diarrhea during the recent days)
• have any severe systemic infection
• have shock or problems in blood circulation

Diet and Lifestyle Advice

Best foods to eat while TEGNECT M 20/500MG TABLET:

• Brown rice, quinoa, whole wheat bread, oats
• Lentils, chickpeas, kidney beans
• Spinach, kale, broccoli, carrots
• Apples, pears, oranges, berries
• Eggs, chicken, fish, tofu & paneer
• Broccoli, cauliflower, cabbage

Exercise tips to enhance the effectiveness of TEGNECT M 20/500MG TABLET:

• Cardiovascular (Aerobic) Exercises
• Strength Training – Builds Muscle & Burns Fat
• Flexibility & Balance Exercises – Manages Diabetes-Related Complications
• High-Intensity Interval Training (HIIT) – Quick & Effective

Foods & drinks to avoid while on TEGNECT M 20/500MG TABLET:

• Sugary foods & high-carb processed foods
• Fried & fatty foods
• Alcohol & caffeinated drinks
• High-sodium foods
• Dairy products with added sugar & artificial sweeteners

How to balance your diet to manage blood sugar spikes:

• Prioritize low-glycemic index (GI) foods
• Eat more protein with every meal
• Add healthy fats for better blood sugar control
• Control carbohydrate intake
• Stay hydrated & avoid sugary drinks
• Eat at regular intervals
• Plan a balanced plate (the diabetes plate method)

Drug - Drug interaction

1. Anti-diabetic medications (Risk of Hypoglycemia):

• Insulin, sulfonylureas (Glimepiride, Gliclazide, Glibenclamide)
• Precaution: Monitor blood sugar levels closely to prevent dizziness, sweating, and shakiness

2. Iodine contrast media (risk of lactic acidosis):

• Iodine-based contrast dyes (used for diagnostic imaging)
• Precaution: Stop TEGNECT M 20/500MG TABLET 48 hours before and after contrast imaging to prevent kidney-related complications

3. Bronchodilators:

• Salbutamol (Albuterol), terbutaline
• Precaution: Monitor blood sugar levels more frequently if using inhalers or nebulizers regularly

4. Corticosteroids:

• Prednisolone, Dexamethasone, Hydrocortisone, Steroid inhalers & injections
• Precaution: If steroids are necessary, adjust diabetes medication under medical supervision

5. Diuretics:

• Furosemide, Hydrochlorothiazide (HCTZ), Spironolactone
• Precaution: Stay hydrated and monitor kidney function regularly

6. NSAIDs:

• Ibuprofen, Naproxen, Diclofenac, Aspirin
• Precaution: Use NSAIDs cautiously and for short durations. Paracetamol is a safer alternative for pain relief

Drug - Food interaction

How does TEGNECT M 20/500MG TABLET compare to Metformin?

TEGNECT M 20/500MG TABLET vs. Insulin – Which works best for Type 2 Diabetes?

Onset of Action:

Synopsis

More Information

FAQs About TEGNECT M 20/500MG TABLET

References

1. KD. Tripathi. Insulin, Oral Hypoglycaemic Drugs and Glucagon. Essentials of medical pharmacology. Seventh edition. 2013. Page – 274 & 275.
2. Linong Ji, Ling Li,  Jianhua Ma, Xuefeng Li, Dongmei Li,  Bangzhu Meng, Weiping Lu, Jiao Sun, Yanmei Liu,  Gen Takayanagi and Yi Wang. Efficacy and safety of teneligliptin added to metformin in Chinese patients with type 2 diabetes mellitus inadequately controlled with metformin: A phase 3, randomized, double-blind, placebo-controlled study. NIH. National Library of Medicine. National Center for Biotechnology Information. PMC. PubMed Central. January 2021. [Accessed on 20th May 2025]
3. Rx Farma Limited. Electronic Medicines Compendium (EMC). [Revised in September 2019] [Accessed on 20th May 2025]
4. Torrent Pharmaceutical Ltd. Teneligliptin. [Revised in April 2021] [Accessed on 20th May 2025]
5. Centaur Pharmaceuticals Pvt Ltd. TEN20 – M. [Accessed on 20th May 2025]
6. Johnlee Pharmaceuticals Pvt Ltd. TENALIP-M 1000. [Accessed on 20th May 2025]

Useful Diagnostic Tests

• Random Blood Sugar (RBS)
• Fasting Blood Sugar (FBS)
• Post Prandial Blood Sugar (PPBS)
• Sugar Risk Package
• HbA1C, Also known as Glycated Hemoglobin, Glycosylated Hemoglobin

Author Details

Written By Dr. Karthikeyan Rajagopal - M.Pharm (Pharmacology)

Reviewed By Dr. Sankara Babu Gorle - MBBS, MD(Pharmacology) View profile

Last updated on 23 May 2025 | 12:58 PM(IST)