Introduction About TACLIMENT EYE OINTMENT

TACLIMENT EYE OINTMENT contains Tacrolimus which belongs to the group of medicines called Immunosuppressants. It is used to manage allergic eye conditions (such as allergic conjunctivitis, keratoconjunctivitis, etc.). It also reduces eye inflammation and dryness. It can also be used to manage corneal graft rejection following corneal transplantation.

Apply a small amount of TACLIMENT EYE OINTMENT into the affected eye(s). It is for ophthalmic use only. Wash your hands before and after application. Avoid touching the tip of the ointment tube with your mouth, nose or other parts of body to avoid contamination.

If you wear soft contact lenses, make sure to remove them before applying TACLIMENT EYE OINTMENT. Consult your doctor about the usage of contact lenses while undergoing management with TACLIMENT EYE OINTMENT.

Before using TACLIMENT EYE OINTMENT inform your doctor if you have pre-existing disease conditions such as autoimmune disease or skin disorders. You must also inform your doctor if you have any liver or kidney problems.

Do not use TACLIMENT EYE OINTMENT if you are pregnant or breastfeeding without consulting your doctor. TACLIMENT EYE OINTMENT is not suitable for use in infants and toddlers aged below 2 years.

The use of TACLIMENT EYE OINTMENT is generally safe and well tolerated. However, it may cause mild eye irritation, discomfort or redness in some individuals. Consult your doctor if this bothers you.

Uses Of TACLIMENT EYE OINTMENT

• Manage Allergic Eye conditions (such as allergic conjunctivitis)
• Reduces eye Inflammation and dryness
• Prevents corneal graft rejection following transplantation

How TACLIMENT EYE OINTMENT Works

TACLIMENT EYE OINTMENT is an immunosuppressive agent. It works by blocking the release of certain chemicals in the body (such as T-cells) that cause allergic and inflammatory reactions. When applied to the eyes, it stops allergic response in the eyes and reduces eye inflammation. It also suppresses the immune system and manages the risk of graft rejection in patients undergoing corneal transplantation.

How to use TACLIMENT EYE OINTMENT

Apply TACLIMENT EYE OINTMENT as directed by the physician. It is for ophthalmic use only. Apply a small amount of the medicine into the affected eye(s). Wash your hands before and after application.

Do not touch the tip of the ointment tube with your mouth, nose or other parts of body to avoid contamination. If you wear soft contact lenses, make sure to remove them before applying TACLIMENT EYE OINTMENT. Consult your doctor about the usage of contact lenses while undergoing management with TACLIMENT EYE OINTMENT.

Your doctor will decide the correct dose and duration of therapy for you depending upon your age, body weight and health condition. Do not stop using TACLIMENT EYE OINTMENT unless your doctor tells you to stop.

Side Effects Of TACLIMENT EYE OINTMENT

How To Manage Side Effects

Eye irritation, redness or discomfort:

Avoid watching direct light sources. Do not strain your eyes too much. Protect your eyes from bright light while going outdoors using sunglasses. Consult your doctor if this side effect bothers you.

Warning & Precautions

Pregnancy

TACLIMENT EYE OINTMENT is generally not recommended for use in pregnant women. However, consult your doctor before using it.

Breastfeeding

TACLIMENT EYE OINTMENT is generally not recommended for use in breastfeeding women. However, consult your doctor before using it.

Driving and Using Machines

Do not drive or operate any heavy tools or machines if you experience any vision problems after applying TACLIMENT EYE OINTMENT.

Alcohol

Avoid consumption of alcohol while using TACLIMENT EYE OINTMENT as it may cause eye redness.

Kidney

TACLIMENT EYE OINTMENT should be used with caution in patients with kidney problems. Therefore, consult your doctor before using it.

Liver

TACLIMENT EYE OINTMENT should be used with caution in patients with liver problems. Therefore, consult your doctor before using it.

Allergy

Talk to your doctor before using TACLIMENT EYE OINTMENT if you are allergic to Tacrolimus or to any macrolide antibiotics (such as erythromycin, azithromycin).

Interactions

A. Drug – drug interactions:

Before using TACLIMENT EYE OINTMENT, inform your doctor if you are using any other medicines on the eyes.

B. Drug -food interaction:

NA

Overdosage:

If you or anyone else accidentally used excessive amount of TACLIMENT EYE OINTMENT, rinse your eyes with plain water to ease the irritation. If you irritation persists, consult your doctor.

Synopsis

More Information

• Keep TACLIMENT EYE OINTMENT out of reach of children
• Store TACLIMENT EYE OINTMENT at room temperature

FAQs About TACLIMENT EYE OINTMENT

What is the use of TACLIMENT EYE OINTMENT?

TACLIMENT EYE OINTMENT is used to manage allergic eye conditions (such as allergic conjunctivitis, keratoconjunctivitis, etc.). It also reduces eye inflammation and dryness. It can also be used to manage corneal graft rejection following corneal transplantation.

How TACLIMENT EYE OINTMENT works?

TACLIMENT EYE OINTMENT is an immunosuppressive agent. It works by blocking the release of certain chemicals in the body (such as T-cells) that cause allergic and inflammatory reactions. When applied to the eyes, it stops allergic response in the eyes and reduces eye inflammation. It also suppresses the immune system and manages the risk of graft rejection in patients undergoing corneal transplantation.

How to use TACLIMENT EYE OINTMENT?

Apply a small amount of the medicine into the affected eye(s). It is for ophthalmic use only. Wash your hands before and after application. If you wear soft contact lenses, make sure to remove them before applying TACLIMENT EYE OINTMENT.

What precautions must be followed while using TACLIMENT EYE OINTMENT?

TACLIMENT EYE OINTMENT is for ophthalmic use only. Wash your hands before and after application. Avoid touching the tip of the ointment tube with your mouth, nose or other parts of body to avoid contamination. If you wear soft contact lenses, make sure to remove them before using TACLIMENT EYE OINTMENT. Before using TACLIMENT EYE OINTMENT inform your doctor if you have pre-existing disease conditions such as autoimmune disease, skin disorders, liver problems or kidney problems or if you are pregnant or breastfeeding.

Is TACLIMENT EYE OINTMENT safe?

The use of TACLIMENT EYE OINTMENT is generally safe and well tolerated. However, it may cause mild eye irritation, discomfort or redness in some individuals. Consult your doctor if this bothers you.

What are the common side effects of using TACLIMENT EYE OINTMENT?

The use of TACLIMENT EYE OINTMENT is generally safe and well tolerated. However, it may cause mild eye irritation, discomfort or redness in some individuals. Consult your doctor if this bothers you.

What to do if I forgot to apply TACLIMENT EYE OINTMENT?

If you forgot to apply a dose of TACLIMENT EYE OINTMENT, apply it as soon as you remember. However, if it is time for the next dose of TACLIMENT EYE OINTMENT, skip the missed dose and apply the next one regularly. Do not apply a double dose of TACLIMENT EYE OINTMENT to compensate the missed ones.

How long will it take for TACLIMENT EYE OINTMENT to heal my condition?

You need to apply TACLIMENT EYE OINTMENT as long as your doctor prescribes you the medicine. Your doctor will decide the correct dose and duration of therapy for you depending upon your age, body weight and disease condition.

Can I use other eye medicines while using TACLIMENT EYE OINTMENT?

Avoid using any other eye medicines along with TACLIMENT EYE OINTMENT without consulting your doctor as it may increase the risk of side effects.

Can TACLIMENT EYE OINTMENT be used in pregnant women?

TACLIMENT EYE OINTMENT is generally not recommended for use in pregnant women. However, consult your doctor before using it.

Who must not use TACLIMENT EYE OINTMENT?

TACLIMENT EYE OINTMENT is generally not recommended for use in pregnant or breastfeeding women. It is also not suitable for use in infants and toddlers aged below 2 years.

Can TACLIMENT EYE OINTMENT reduce conjunctivitis?

Yes. TACLIMENT EYE OINTMENT can be used to manage allergic eye conditions (such as allergic conjunctivitis, keratoconjunctivitis, etc.).

Can TACLIMENT EYE OINTMENT be used in children?

TACLIMENT EYE OINTMENT should be used in children and adolescents (aged between 2-18 years) only if prescribed by the physician. It is not recommended for use in children aged below 2 years. However, consult your doctor for advice.

References

1. Alan G. Kabat. Uveitis. Clinical Ocular Pharmacology by Jimmy D Barlett, Siret D Jaanus. Fifth edition. 2007. Page – 595
2. Morgana Arima Vedovato, Queiroz Thaynara, Do Mendes, Carmo. Use of Topical Tacrolimus in Ophthalmology: Nonsystematic Review. ResearchGate. December 2020. [Accessed on 19th October 2022] https://www.researchgate.net/publication/347288480_Use_of_Topical_Tacrolimus_in_Ophthalmology_Nonsystematic_Review
3. Sunil Kumar, Rajiv Kumar. Efficacy and Safety of Tacrolimus Eye Ointment in Refractory Vernal Keratoconjunctivitis in Eastern India. International Journal of Contemporary Medical Research. November 2016. [Accessed on 19th October 2022] https://www.ijcmr.com/uploads/7/7/4/6/77464738/ijcmr_1077_dec_10.pdf
4. Ajit Kumar Hazarika and Prodip Kumar Singh. Efficacy of topical application of 0.03% tacrolimus eye ointment in the management of allergic conjunctivitis. NIH. National Library of Medicine. National Center for Biotechnology Information. PMC. PubMed Central. August 2015. [Accessed on 19th October 2022] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4630738/
5. Vera Lucia LiendoMaria Eugenia VolaTelma Pereira BarreiroTais Hitomi WakamatsuJosé Álvaro Pereira GomesMyrna Serapião dos Santos. Topical tacrolimus for the treatment of severe allergic keratoconjunctivitis in children. Scielo Brazil. July-August 2017. [Accessed on 19th October 2022] https://www.scielo.br/j/abo/a/HGfBVHdpmKqZjGwJ35Qxb9K/?lang=en
6. Otavio A Magalhaes, Diane R Marinho, Sergio Kwitko. Topical 0.03% tacrolimus preventing rejection in high-risk corneal transplantation: a cohort study. NIH. National Library of Medicine. National Center for Biotechnology Information. Pubmed.gov. November 2013. [Accessed on 19th October 2022] https://pubmed.ncbi.nlm.nih.gov/24008822/
7. Astellas Ireland Co. Ltd. Electronic Medicines Compendium (EMC). [Revised in June 2021] [Accessed on 19th October 2022] https://www.medicines.org.uk/emc/files/pil.1612.pdf
8. Glenmark Pharmaceuticals Inc., USA. Tacrolimus (ta-KROE-li-mus) Ointment 0.03% Ointment 0.1%. [Revised in March 2021] [Accessed on 19th October 2022] https://glenmarkpharma-us.com/wp-content/uploads/Tacrolimus-Ointment-Medication-Guide.pdf
9. Acrotak (Eye Ointment). Pharmatak Ophthalmics (I) Pvt Ltd. [Accessed on 19th October 2022] https://www.pharmtakindia.com/product/acrotak-eye-ointment/