Introduction About SELZIC OD 150MG TABLET

SELZIC OD 150MG TABLET is used to manage partial seizures in adults with epilepsy as monotherapy or adjunctive therapy. It contains Oxcarbazepine which belongs to the group of medicines called Anti-epileptics.

Prior to management with the medicine, your doctor may want you to take several blood tests to understand existing condition and to safely use the medicine and to decide the appropriate dose of this medicine. Before taking, inform your doctor if you have liver, kidney or heart problems or intolerance to certain sugars (such as lactose).  

SELZIC OD 150MG TABLET should be used during pregnancy only if the potential benefit justifies the potential risk to the foetus. The most common side effects are dizziness, nausea, vomiting, headaches, diarrhoea, constipation, stomach pain and skin rash. Consult your doctor if any of the side effects worsen.

Uses Of SELZIC OD 150MG TABLET

• It is used to manage partial seizures in adults with epilepsy as monotherapy or adjunctive therapy

How SELZIC OD 150MG TABLET Works

SELZIC OD 150MG TABLET helps to control electrical activity in the brain (by binding to sodium channels) which is out of control in epileptic patients. Thus, reducing the chances of having seizures.

How to use SELZIC OD 150MG TABLET

• Take SELZIC OD 150MG TABLET as advised by your physician
• Swallow the medicine with a glass of water. Do not crush or chew the medicine
• Your doctor will decide the correct dose and duration for you depending upon your age, body weight and disease condition
• Do not stop taking the medicine unless your doctor advises you to stop

Side Effects Of SELZIC OD 150MG TABLET

Common side effects of SELZIC OD 150MG TABLET:

• dizziness, tiredness, drowsiness
• nausea, vomiting, diarrhoea, constipation, stomach pain
• headache
• depression, confusion, difficulty concentrating
• low blood levels of sodium
• agitation, other mood changes
• lack of emotion or motivation
• disturbed, blurred or double vision
• uncontrolled eye movement
• loss of coordination, shaking
• spinning sensation

Stop taking SELZIC OD 150MG TABLET and contact your doctor immediately if you experience any of the following side effects:

• signs of low number of white blood cells (increase in the number of infections with fever, severe chills, sore throat or mouth ulcers)
• signs of a blood disorder (tiredness, breathlessness when exercising, looking pale, headache, chills, dizziness, infections leading to fever, sore throat, mouth ulcer, bleeding or bruising more easily than normal, nose bleeding, reddish or purplish patches, unexplained blotches on skin)

Warning & Precautions

Pregnancy

Monitoring required

SELZIC OD 150MG TABLET should be used during pregnancy only if the potential benefit justifies the potential risk to the foetus.

Breastfeeding

Consult your doctor

Inform your doctor if you are a breastfeeding women, before taking the medicine.

Driving and Using Machines

Use with Caution

Do not drive or operate any machines after taking SELZIC OD 150MG TABLET if you experience dizziness, drowsiness, balance or co-ordination problems, eye problems like double or blurred vision, low blood levels of sodium causing muscle weakness or decreased consciousness, especially when starting the management or increasing the dose.

Alcohol

Consult your doctor

Avoid consumption of alcohol while taking SELZIC OD 150MG TABLET as it might make you feel very drowsy.

Kidney

Use with Caution

SELZIC OD 150MG TABLET should be used with caution in patients with kidney problems (especially associated with low sodium levels in the blood). Your doctor may initiate the management with the lowest effective dose and may gradually increase the dose of this medicine. Your doctor will examine your blood before management and at regular intervals during management with this medicine.  

Liver

Use with Caution

SELZIC OD 150MG TABLET should be used with caution in patients with liver problems or who develop liver problems during management and in serious liver problems your doctor may adjust the dose.  

Allergy

Contraindicated

Do not take SELZIC OD 150MG TABLET if you are allergic to Oxcarbazepine or any other ingredients of this medicine.

Heart Disease

Use with Caution

SELZIC OD 150MG TABLET should be used with caution in patients with heart failure (signs include breathlessness, swelling of the feet or legs due to fluid build-up) or heart rhythm disorder.

Use In Pediatrics

Consult your doctor

Dose for children SELZIC OD 150MG TABLET can be taken by children aged 6 years or above. Your doctor will give the right dose depends on your child’s age, body weight and disease condition.

Use In Geriatrics

Use with Caution

SELZIC OD 150MG TABLET should be used with caution in elderly patients (aged 65 years and above), especially in patients with kidney impairment and your doctor may adjust the dose.

Interactions

A. Drug-Drug interactions:

Before taking SELZIC OD 150MG TABLET, inform your doctor if you are taking any of the following medicines:

• Antiepileptics fits (Ex. phenobarbital, phenytoin, carbamazepine, lamotrigine and valproic acid)
• Hormonal medicines (Ex. ethinyl estradiol, desogestrel)
• Antidepressants (Ex. lithium, phenelzine and moclobemide)
• Diuretics (Ex. furosemide, spironolactone)
• Antidiuretic hormones (Ex. desmopressin)
• Non-steroidal anti-inflammatory agents (Ex. indomethacin, ibuprofen)
• Immunosuppressants (Ex. ciclosporin, tacrolimus)
• Antibiotics (Ex. rifampicin)

Overdosage:

If you or anyone else accidentally takes too much of SELZIC OD 150MG TABLET, consult your doctor immediately or visit the nearby hospital. Overdosage symptoms are low blood levels of sodium, anger, agitation, confusion, drowsiness or sleepiness, dizziness, nausea, vomiting, tiredness, fast or irregular heartbeat, headache, uncontrolled twitching or jerking, double or blurred vision, lack of coordination of movements and uncontrolled eye movements.

Synopsis

More Information

FAQs About SELZIC OD 150MG TABLET

References

1. Barbara G. Wells, Joseph T. DiPiro, Terry L. Shwinghammer, Cecily V. DiPiro. Epilepsy. Pharmacotherapy Handbook. Ninth edition. 2015. Page-518.

2. S M Grant, D Faulds. Oxcarbazepine. A review of its pharmacology and therapeutic potential in epilepsy, trigeminal neuralgia and affective disorders. NIH. National Center for Biotechnology Information.Pubmed.gov. June 1992. [Accessed on 4th June 2024] click here

3. Charles V. Preuss, Gagandeep Randhawa, Tom Joshua P. Wy, Abdolreza Saadabadi. Oxcarbazepine. NIH. National Library of Medicine. National Center for Biotechnology Information. May 2022. [Accessed on 4th June 2024] click here

4. Gerard Laboratories. Electronic Medicines Compendium (EMC). [Revised in August 2022] [Accessed on 4th June 2024] click here

5. Torrent Pharmaceuticals Ltd. Oleptal OD (Oxcarbazepine). [Revised in July 2019] [Accessed on 4th June 2024] click here

6. Central Drugs Standard Control Organization (CDSCO). Oxcarbazepine. [Accessed on 4th June 2024] click here

Author Details

Written By Srilekha. R - B.Pharm

Reviewed By Dr. Sankara Babu Gorle - MBBS, MD(Pharmacology) View profile

Last updated on 21 Nov 2024 | 03:10 PM(IST)