ROXITHRAL A Tablet 10's
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Introduction About ROXITHRAL A TABLET
ROXITHRAL A TABLET is a combination of Ambroxol and Roxithromycin, which belong to the group of medicines called Mucolytic and Macrolide antibiotics, respectively. It is used to manage respiratory infections from both the upper and lower airways (such as otitis, sinusitis, pharyngitis, tonsillitis, bronchitis, and pneumonia). Respiratory tract infections (RTIs) are infections of parts of the body that are involved in breathing (such as the sinuses, throat, airways, or lungs).
Otitis is an inflammation of the ear. Sinusitis is an inflammation or swelling of the tissue of the sinus lining. Pharyngitis is inflammation of the pharynx, which is in the back of the throat. It is most often mentioned simply as a sore throat. Tonsillitis is inflammation of the tonsils (the tonsils are two oval-shaped tissue pads at the back of the throat). Bronchitis is when the tubes that carry air to the lungs, called the bronchial tubes, get inflamed and swollen. Pneumonia is an infection and inflammation of the lungs' air sacs.
Before taking this medicine, tell your doctor if you have serious liver problems, heart problems, kidney problems, myasthenia gravis, or peptic ulcers. ROXITHRAL A TABLET is not recommended for use among pregnant and breastfeeding women. ROXITHRAL A TABLET is not recommended for use in children under 6 years of age and should be used with caution in elderly patients.
The most common side effects of ROXITHRAL A TABLET are nausea or vomiting, diarrhea, changes in sense of taste, and numbness in the throat and mouth. Consult your doctor for advice if the condition persists or worsens.
Uses Of ROXITHRAL A TABLET
ROXITHRAL A TABLET is used to manage respiratory infections from both the upper and lower airways (such as otitis, sinusitis, pharyngitis, tonsillitis, bronchitis, and pneumonia).
How ROXITHRAL A TABLET Works
ROXITHRAL A TABLET contains Ambroxol and Roxithromycin. Ambroxol works by thinning and losing the mucus (phlegm), making it easier to cough out. Roxithromycin works by stopping bacterial growth by inhibiting the synthesis of essential proteins, which are required by bacteria to carry out vital functions. The addition of ambroxol enhances the antibacterial effect of roxithromycin. Together with Ambroxol and Roxithromycin, it helps manage respiratory infections.
How to use ROXITHRAL A TABLET
Take ROXITHRAL A TABLET as advised by your physician. Swallow the ROXITHRAL A TABLET with enough water. Do not crush or chew the medicine. The correct dose and duration will be decided by your doctor for you depending on your age, body weight, and disease condition.
Side Effects Of ROXITHRAL A TABLET
Common
- nausea
- vomiting
- diarrhoea
- changes in sense of taste
- numbness in the throat and the mouth
Uncommon
- indigestion
- stomach pain
- dry mouth
Rare
- hypersensitivity reactions
- rash
- hives
Stop taking ROXITHRAL A TABLET and contact your doctor immediately if you experience any of the following side effects:
- severe skin reactions (symptoms include rash and lesions on the mucous membranes of the mouth, throat, nose, eyes, and reproductive organs)
- vaginal itching, soreness, or discharge
- fainting
- changes in the heartbeat (fast or irregular)
- signs of liver problems (such as yellowing of the skin or eyes, dark urine, and pain in the abdomen)
- allergic reactions such as skin rash, itching, swelling of the mouth, lips, or face, or difficulty breathing
- severe diarrhea
How To Manage Side Effects
Diarrhea
Drink lots of fluids, such as water, to keep yourself hydrated. Avoid eating high-fat or spicy foods. Try to avoid taking any medicine on your own to manage diarrhea and consult your doctor if the diarrhea gets worse.
Nausea And Vomiting
Take this medicine with meals or just after meals. Stick to simple meals. Avoid eating rich or spicy food. Consult your doctor if nausea and vomiting persist.
Stomach Pain
Try to rest and relax. Eat and drink gradually, or try to have smaller, more frequent meals. Keep a heating pad on your stomach. If the stomach pain does not improve, contact your physician for advice.
Warning & Precautions
Pregnancy
ContraindicatedROXITHRAL A TABLET is generally not recommended for use in pregnant women. Consult your physician for advice before taking ROXITHRAL A TABLET.
Breastfeeding
ContraindicatedROXITHRAL A TABLET is generally not recommended for use in breastfeeding women. Consult your physician for advice before taking ROXITHRAL A TABLET.
Driving and Using Machines
Use with CautionDo not drive or operate any machines if you feel dizzy after taking ROXITHRAL A TABLET.
Alcohol
Consult your doctorAvoid consumption of alcohol while taking ROXITHRAL A TABLET, as it worsens the side effects.
Kidney
Use with CautionROXITHRAL A TABLET should be used with caution if you have any kidney problems. Consult your physician for advice before taking ROXITHRAL A TABLET.
Liver
Consult your doctorROXITHRAL A TABLET is generally not recommended to use in patients with severe hepatic impairment, and it should be used with caution if you have any liver problems like hepatic cirrhosis with jaundice and/or ascites. Consult your physician for advice before taking ROXITHRAL A TABLET.
Allergy
ContraindicatedDo not take ROXITHRAL A TABLET if you are allergic to ambroxol, roxithromycin, or any of the other ingredients of this medicine.
Heart Disease
Use with CautionROXITHRAL A TABLET should be used with caution if you have any heart problems. Consult your physician for advice before taking ROXITHRAL A TABLET.
Use In Pediatrics
Consult your doctorROXITHRAL A TABLET is generally not recommended to use in children below 6 years of age and should be used with caution in children above 6 years of age. Consult your physician for advice before taking ROXITHRAL A TABLET.
Use In Geriatrics
Use with CautionROXITHRAL A TABLET should always be used with caution in elderly patients. Consult your physician for advice before taking ROXITHRAL A TABLET.
Others
Before taking ROXITHRAL A TABLET, inform your doctor if you:
- have bronchial motor activity syndrome with a large production of secretion (risk of a mucous plug)
- have peptic ulcers
Interactions
A. Drug-Drug interactions:
Before taking ROXITHRAL A TABLET, inform your doctor if you are taking any of the following medicines, such as:
- medicine used to manage asthma (Ex. theophylline)
- medicines used to manage migraine headaches (Ex. ergotamine or dihydroergotamine)
- medicine used to manage irregular heart rhythms (Ex. disopyramide)
- medicines used to manage allergies (Ex. terfenadine and astemizole)
- medicine used to manage blood clots (Ex. warfarin)
- medicine used to manage heart failure (Ex. digoxin)
- medicine used to induce sleep before operations (Ex. midazolam)
- medicine used to manage organ transplant rejection or to manage certain problems with the immune system (Ex. cyclosporin)
- medicine used to manage gastrointestinal problems (Ex. cisapride)
- medicine used as antipsychotic (Ex. pimozide)
Overdosage:
If you or anyone else accidentally takes too much of ROXITHRAL A TABLET, consult your doctor immediately or visit the nearby hospital.
Synopsis
| Drug | : | Ambroxol, Roxithromycin |
| Pharmacological Category | : | Mucolytic and Macrolide antibiotics, respectively |
| Therapeutic Indication | : | Respiratory infections |
| Dosage Forms | : | Tablet, Kid Tablet |
More Information
Storage
- Keep out of reach of children
- Store at a temperature below 25°C
FAQs About ROXITHRAL A TABLET
Q: Is it safe to use ROXITHRAL A TABLET while pregnant or nursing?
A: ROXITHRAL A TABLET is generally not recommended for use by pregnant or breastfeeding women. Consult your physician for advice before taking ROXITHRAL A TABLET.
Q: Can I use ROXITHRAL A TABLET in patients who have liver disease?
A: ROXITHRAL A TABLET is generally not recommended for use in patients with severe hepatic impairment, and it should be used with caution if you have any liver problems like hepatic cirrhosis with jaundice and/or ascites. Consult your physician for advice before taking ROXITHRAL A TABLET.
Q: When should you seek medical attention in an emergency?
A: Stop taking ROXITHRAL A TABLET and contact your doctor immediately if you experience any of the following side effects: severe skin reactions (symptoms include rash, lesions on the mucous membranes of the mouth, throat, nose, eyes, and reproductive organs), vaginal itching, soreness, or discharge, fainting, changes in the heartbeat (fast or irregular), signs of liver problems (such as yellowing of the skin or eyes, dark urine, pain in the abdomen), and allergic reactions such as skin rash, itching, swelling of the lips, face, or mouth, or changes in the
Q: Does ROXITHRAL A TABLET cause dry mouth?
One of the common side effects of ROXITHRAL A TABLET is dry mouth. It is not necessary for everyone taking ROXITHRAL A TABLET to experience this side effect. To avoid such side effects, drink plenty of water, regularly rinse your mouth, practice good oral hygiene, and suck on sugarless candy. However, if the condition persists or worsens, please consult a doctor.
Q: What are the common side effects of ROXITHRAL A TABLET?
A: The most common side effects of ROXITHRAL A TABLET are nausea or vomiting, diarrhea, changes in sense of taste, and numbness in the throat and mouth. Consult your doctor if the condition persists or worsens.
Q: What is ROXITHRAL A TABLET used for?
A: ROXITHRAL A TABLET is used to manage respiratory infections from both the upper and lower airways (such as otitis, sinusitis, pharyngitis, tonsillitis, bronchitis, and pneumonia). Consult your doctor before taking it.
Q: What should I avoid while taking ROXITHRAL A TABLET?
A: Avoid consumption of alcohol while taking ROXITHRAL A TABLET, as it worsens the side effects.
Q: What precautions must be taken while using ROXITHRAL A TABLET?
A: Before taking ROXITHRAL A TABLET, inform your doctor if you have any kidney, liver, or heart problems, bronchial motor activity syndrome with a large production of secretion (risk of a mucous plug), or have peptic ulcers. Consult your physician for advice before taking ROXITHRAL A TABLET.
Q: Who should avoid taking ROXITHRAL A TABLET?
A: ROXITHRAL A TABLET is generally not recommended for use in patients with severe hepatic impairment, allergic to ambroxol, or roxithromycin.
Q: Is ROXITHRAL A TABLET safe for kids?
A: ROXITHRAL A TABLET is generally not recommended for use in children below 6 years of age and should be used with caution in children above 6 years of age. Consult your physician for advice before taking ROXITHRAL A TABLET.
References
1. KD Tripathi. Drugs for Cough and Bronchial Asthma and Macrolide, Lincosamide, Glycopeptide, and Other Antibacterial Antibiotics; Urinary Antiseptics. Essentials of Medical Pharmacology. Seventh Edition. 2013. Page – 219, 754.
2. Ahmad Kantar, Ludger Klimek, Dorotheea Cazan, Annette Sperl, Ulrike Sent, and Margarida Mesquita. An overview of efficacy and safety of ambroxol for the treatment of acute and chronic respiratory diseases with special regard to children. Journal of Multidisciplinary Respiratory Medicine. March 2020. [Accessed on 14th September 2024] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7137760/
3. BC Cooper, PR Mullins, MR Jones, and SD Lang. Clinical efficacy of roxithromycin in the treatment of adults with upper and lower respiratory tract infection due to Haemophilus influenza: a meta-analysis of 12 clinical studies. Database of Abstracts of Reviews of Effects (DARE). 1994. [Accessed on 14th September 2024] https://www.ncbi.nlm.nih.gov/books/NBK66222/
4. Siwasak Juthong, Sarayuth Eiamsa-ard. Roxithromycin as Anti-Inflammatory Drug Improves Clinical Outcomes in Adult Patients with Bronchiectasis: A Double-Blinded Randomized, Placebo-Controlled Pilot Clinical Trial. Journal of Health Science and Medical Research. 2019. [Accessed on 14th September 2024] https://www.jhsmr.org/index.php/jhsmr/article/view/56
5. Roxithromycin. http://www.medizzine.com/ December 2010. [Accessed on 14th September 2024] http://www.medizzine.com/en/patients/drugs/R/roxithromycin.php#f
6. Sandoz. Ravimiregister. [Revised in June 2016]. [Accessed on 14th September 2024] https://www.ravimiregister.ee/Data/PIL_ENG/PIL_10403_ENG.pdf
7. Ambrosan. promed.cz. [Accessed on 14th September 2024] https://www.promed.cz/en/non-prescription-drugs/ambrosan-60-mg-tablets
8. Health Navigator. www.healthnavigator.org.nz. [Revised in May 2022] [Accessed on 14th September 2024] https://www.healthnavigator.org.nz/medicines/r/roxithromycin/
9. Roxithromycin. MIMS. [Accessed on 14th September 2024] https://www.mims.com/india/drug/info/roxithromycin?type=full&mtype=generic
10. Teva Pharma Limited. Arrow tablet [Revised in February 2017] [Accessed on 14th September 2024] https://www.medsafe.govt.nz/consumers/cmi/a/arrow-roxithromycin.pdf
Useful Diagnostic Tests
- Complete Blood Count (CBC)/ Hemogram
- Total IGE
- Wheeze/Rhinitis Comprehensive Panel Adult
- Basic Allergy Package
- Absolute Eosinophil Count, Blood
- Allergy Comprehensive Profile
- Allergy Post Screening Profile
- Allergy Screen (Includes Total Ige And Alatop)
- Infection Checkup Profile
Author Details
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