Introduction About ROXIL 50MG TABLET

ROXIL 50MG TABLET contains Roxithromycin which belongs to the group of medicines called Antibiotics. It is used to manage mild to moderately severe bacterial infections in children such as acute pharyngitis and tonsillitis (inflammation of pharynx or tonsils characterized by sore throat and pain during swallowing), skin and soft issues infections like impetigo (contagious skin infections that predominantly affects infants and young children characterised with red sores around the face, mouth, and nose).

Prior to the management, your doctor may want you to take several blood tests to examine your child’s existing condition.

ROXIL 50MG TABLET is not recommended for use in children having severely impaired liver function. Consult your doctor before giving ROXIL 50MG TABLET to your child.

It should be used with caution among children with impaired kidney function and heart diseases. Consult your doctor before giving ROXIL 50MG TABLET to your child.

Your doctor will prescribe the right dose and duration depends on your child’s age, body weight and severity of the infection. Consult your doctor before giving ROXIL 50MG TABLET to your child.

ROXIL 50MG TABLET may cause minor side effects such as nausea, vomiting, stomach pain, diarrhoea, flatulence although not everybody gets them. Consult your doctor if any of the side effects worsen or persist for a longer duration.

Uses Of ROXIL 50MG TABLET

It is used to manage bacterial infections in children such as:

• acute pharyngitis
• acute tonsillitis
• skin and soft issues infections like impetigo

How ROXIL 50MG TABLET Works

ROXIL 50MG TABLET works by inhibiting the protein synthesis through cell wall penetration of the suspectable organisms and binding on the 50 S ribosomal subunit of bacteria thereby terminating the bacterial growth. As a result, it blocks the growth of the bacteria and stops the infection from spreading.

How to use ROXIL 50MG TABLET

Give ROXIL 50MG TABLET to your child as per the physician’s advice.

For Tablet, Capsule: ROXIL 50MG TABLET should be taken with a glass of water and do not crush or chew the medicine.

For Dispersible Tablet: Disperse ROXIL 50MG TABLET in the specified quantity of water as mentioned in the label. Then mix it well and give your child to drink it immediately.

Your doctor will decide the correct dose and duration of therapy for your child depending upon your child’s age, body weight and severity of infection. Continue to give ROXIL 50MG TABLET for the stipulated duration prescribed by your doctor to achieve better results.

Side Effects Of ROXIL 50MG TABLET

Warning & Precautions

Driving and Using Machines

Do not allow your child drive or play outdoors, as ROXIL 50MG TABLET may cause dizziness or blurry vision. Consult your doctor before giving ROXIL 50MG TABLET.

Kidney

ROXIL 50MG TABLET should be used with caution in children having impaired kidney function. Consult your doctor for advice before giving ROXIL 50MG TABLET.

Liver

ROXIL 50MG TABLET is not recommended for use in children having severely impaired liver function (liver cirrhosis with jaundice and/or ascites). Consult your doctor before giving ROXIL 50MG TABLET.

Allergy

Do not give ROXIL 50MG TABLET if your child is allergic to Roxithromycin or macrolide antibiotics (Ex. azithromycin, erythromycin, or clarithromycin), or any other ingredients of this medicine.

Heart Disease

ROXIL 50MG TABLET should be given with caution in child having heart diseases. Consult your doctor before giving ROXIL 50MG TABLET.

Interactions

A. Drug-Drug interactions:

Before giving ROXIL 50MG TABLET, inform your doctor if your child is taking any of the following medicine:

• theophylline (medicine used to manage asthma)
• ergotamine or dihydroergotamine (used to manage migraine headache)
• terfenadine, astemizole (medicines used to manage allergic conditions)
• cisapride (used to manage heartburns and gastrointestinal problems)
• pimozide (used to manage psychosis)
• warfarin, phenprocoumon (used to manage blood clots)
• ciclosporin (medicine used to manage graft rejection after organ transplantation)
• chloroquine or hydroxychloroquine (used to manage malaria)
• rifabutin and bromocriptine (used in the management of HIV infections)

Overdosage:

If your child or anyone else accidentally took too much of ROXIL 50MG TABLET, consult your doctor immediately or visit any nearby hospital.

Synopsis

More Information

• Keep ROXIL 50MG TABLET out of reach of children
• Store ROXIL 50MG TABLET at room temperature

FAQs About ROXIL 50MG TABLET

What is the use of ROXIL 50MG TABLET?

ROXIL 50MG TABLET manages mild to moderately severe bacterial infections in children such acute pharyngitis, acute tonsillitis, skin, and soft issues infections like impetigo.

When should I give ROXIL 50MG TABLET to my child?

ROXIL 50MG TABLET should be given at least 15 minutes before food or on an empty stomach (3 hours after a meal). Your doctor will decide the correct dose and duration for your child depending upon the age, body weight and disease condition.

Who should avoid taking ROXIL 50MG TABLET?

ROXIL 50MG TABLET is not recommended for use in children having severely impaired liver function. Consult your doctor before giving ROXIL 50MG TABLET.

What should I do if I forget to give ROXIL 50MG TABLET to my child?

Try to give the medicine at the same time each day. If you have missed a dose by chance, try to administer the ROXIL 50MG TABLET as soon as possible when you notice. However, if the time for next dose is closer, skip the dosage and do not try to give the double dosage.

Can I stop giving ROXIL 50MG TABLET to child on my own?

Do not stop giving ROXIL 50MG TABLET on your own without doctor’s advice. When the course of management is not complete or doses are skipped, it will not completely clear the infection, or the symptoms may reoccur.

References

1. KD. Tripathi. Macrolide, Lincosamide, Glycopeptide and Other Anti bacteria Antibiotics; Urinary Antiseptics. Essentials of medical pharmacology. Eighth edition. 2019. Page –805.

2. Roxithromycin. NIH National Library of Medicine, National Centre for biotechnology information. PubChem. October 2022. [Accessed 29th October 2022] https://pubchem.ncbi.nlm.nih.gov/compound/Roxithromycin

3. J.K. Aronson. ScienceDirect. Roxithromycin. 2016. [Accessed 29th October 2022]  https://www.sciencedirect.com/topics/pharmacology-toxicology-and-pharmaceutical-science/roxithromycin

4. Sanofi-Aventis Australia Private Ltd. RULIDE & RULIDE D (ROXITHROMYCIN). [Revised in October 2022] [Accessed 29th October 2022] https://secure.guildlink.com.au/gc/ws/sw/pi.cfm?product=swprulid

5. Sanofi Aventis Australia Private Ltd. RULIDE D (ROXITHROMYCIN). [Revised in September 2020] [Accessed 29th October 2022] https://apps.medicines.org.au/files/swcruldd.pdf

Useful Diagnostic Tests

• Complete blood count