Introduction About REFZIL O 500MG TABLET

REFZIL O 500MG TABLET is used in the management of bacterial infections such as bronchitis, respiratory tract infections (such as pneumonia), sinusitis, urinary tract infections, skin infections, ear infections, tonsils, throat infections, etc. It contains Cefprozil which is a cephalosporin antibiotic which works by killing the susceptible bacteria that causes the infection.

Take REFZIL O 500MG TABLET as advised by your physician. It can be taken with or without meals. Do not skip doses or stop taking this medicine without consulting your doctor, even if you feel better, as it could make the medicine less effective against complete eradication of the infections.

Before taking REFZIL O 500MG TABLET inform your doctor if you are allergic to cephalosporin antibiotics, penicillins, cefdinir or similar medicines, have a previous history of developing severe diarrhea and stomach pain after taking antibiotics, are suffering from colitis, kidney problems, or if you are pregnant or breastfeeding.

The most common side effects of taking REFZIL O 500MG TABLET are nausea, vomiting, headache and dizziness. Consult your doctor if they trouble you. Inform your doctor immediately if you experience severe stomach pain with blood diarrhea or fever, chills and flu-like symptoms after taking this medicine.

Uses Of REFZIL O 500MG TABLET

Used in the management of bacterial infections such as:

• Bronchitis, sinusitis, tonsilitis, throat infections
• Respiratory tract infections (pneumonia)
• Skin infections
• Ear infections

How REFZIL O 500MG TABLET Works

REFZIL O 500MG TABLET contains Cefprozil which is a powerful antibiotic. It works by binding to the bacteria cell wall and inhibiting peptidoglycan synthesis, an essential component in bacterial cells that is required to keep cell wall stronger. This action, causes lysis of bacterial cell wall, disrupting cell components, followed by inactivation of the bacteria cells. Hence, Cefdinir is effective in managing severe bacterial infections.

How to use REFZIL O 500MG TABLET

Take REFZIL O 500MG TABLET as advised by your physician. It can be taken with or without meals.

For Tablet, Capsule: Swallow the medicine with a glass of water. Do not crush or chew the medicine.

For Dispersible Tablet: Disperse the medicine in a glass of water before consumption.

Your doctor will decide the correct dose and duration of therapy for you based on your age, body weight and severity of infection.

Follow the dosing schedule as advised by your physician to achieve better results. Do not skip doses or stop taking this medicine without consulting your doctor, even if you feel better, as it could make the medicine less effective against complete eradication of the infections.

Side Effects Of REFZIL O 500MG TABLET

How To Manage Side Effects

Dizziness Or Drowsiness

Sit or lie down as soon as you feel dizzy to prevent falls and stay still until the sensation passes. Slowly change positions, especially when getting up from sitting or lying down, to avoid sudden drops in blood pressure. Staying hydrated is key, as dehydration can cause or worsen dizziness. Ensure you're eating regularly to maintain blood sugar levels, and avoid alcohol or caffeine, which can exacerbate dizziness. Resting in a cool, quiet environment can help, especially if the dizziness is related to stress or overheating. If dizziness persists or is accompanied by other symptoms like chest pain or severe headache, seek medical attention.Top of FormBottom of Form

Nausea And Vomiting

Taking the antibiotic with food can help, as it can reduce stomach irritation. However, check if the specific antibiotic can be taken with food, as some require an empty stomach for proper absorption. Staying hydrated is essential; drinking small sips of water throughout the day can help ease nausea. Eating smaller, more frequent meals with bland, easy-to-digest foods like crackers, toast, or rice can also alleviate symptoms. Ginger, whether in tea or as a supplement, is known to help with nausea. If the nausea persists or worsens, it’s important to consult a healthcare provider, as they might adjust the dosage or switch to a different antibiotic.

Warning & Precautions

Pregnancy

Contraindicated

Do not take REFZIL O 500MG TABLET without consulting your doctor if you are pregnant or think you may be pregnant. Therefore, consult your doctor before use.

Breastfeeding

Contraindicated

Do not take REFZIL O 500MG TABLET without consulting your doctor if you are breastfeeding. Therefore, consult your doctor before use.

Driving and Using Machines

Use with Caution

Do not drive or operate any heavy machines or tools if your ability is affected by REFZIL O 500MG TABLET.

Kidney

Use with Caution

REFZIL O 500MG TABLET should be used with caution in patients with kidney problems. Therefore, consult your doctor for advice before taking it.

Allergy

Contraindicated

Do not take REFZIL O 500MG TABLET if you are allergic to Cefprozil, penicillins or any other medicines of cephalosporin drug class.

Use In Pediatrics

Consult your doctor

REFZIL O 500MG TABLET should be used with caution in children and adolescents. It should not be used in infants aged below 6 months, due to lack of safety data. Therefore, consult your doctor before administering REFZIL O 500MG TABLET to children.

Use In Geriatrics

Use with Caution

REFZIL O 500MG TABLET should be used with caution in elderly patients. Therefore, consult your doctor before taking it.

Interactions

A. Drug-Drug Interactions:

• Aminoglycoside antibiotics (such as streptomycin, gentamicin, kanamycin)
• Probenecid (used for gout management)
• Iron supplements

Overdosage:

If you or anyone else accidentally took too many doses of REFZIL O 500MG TABLET, consult your doctor for advice immediately. Symptoms of overdosage might include nausea, vomiting, epigastric distress, diarrhea, and convulsions.

Synopsis

More Information

FAQs About REFZIL O 500MG TABLET

Q: What is REFZIL O 500MG TABLET used for?

A: REFZIL O 500MG TABLET is used in the management of bacterial infections such as bronchitis, respiratory tract infections (such as pneumonia), sinusitis, urinary tract infections, skin infections, ear infections, tonsils, throat infections, etc. It contains Cefprozil which is a cephalosporin antibiotic which works by killing the susceptible bacteria that causes the infection.

Q: How REFZIL O 500MG TABLET works in the body?

A: REFZIL O 500MG TABLET contains Cefdinir which is a powerful antibiotic. It works by binding to the bacteria cell wall and inhibiting peptidoglycan synthesis, an essential component in bacterial cells that is required to keep cell wall stronger. This action, causes lysis of bacterial cell wall, disrupting cell components, followed by inactivation of the bacteria cells. Hence, Cefdinir is effective in managing severe bacterial infections.

Q: Can I stop taking REFZIL O 500MG TABLET once I feel better?

A: Follow the dosing schedule as advised by your physician to achieve better results. Do not skip doses or stop taking this medicine without consulting your doctor, even if you feel better, as it could make the medicine less effective against complete eradication of the infections.

Q: Is REFZIL O 500MG TABLET safe?

A: REFZIL O 500MG TABLET is safe when used under careful medical supervision. It may cause nausea, vomiting, stomach upset, headache or dizziness in some individuals. Therefore, consult your doctor for advice if they trouble you.

Q: When can I see an improvement in my condition after taking REFZIL O 500MG TABLET?

A: It may take around 1-2 weeks of therapy to start noticing improvement. However, the therapy duration can take around 1 month or more based on the severity of infection.

Q: Can REFZIL O 500MG TABLET be used during pregnancy?

A: Do not take REFZIL O 500MG TABLET without consulting your doctor if you are pregnant or think you may be pregnant. Therefore, consult your doctor before use.

Q: Can REFZIL O 500MG TABLET be used in children?

A: REFZIL O 500MG TABLET should be used with caution in children and adolescents. It should not be used in infants aged below 6 months, due to lack of safety data. Therefore, consult your doctor before administering REFZIL O 500MG TABLET to children.

References

1. KD. Tripathi. Essentials of Medical Pharmacology. 8th Edition. Beta-Lactam antibiotics. Page-777.

2. Cefprozil. A review of its antibacterial activity, pharmacokinetic properties, and therapeutic potential. NCBI. National Center for Biotechnology information. National library of Medicine. February 1993. [Accessed on 14th August 2024] https://pubmed.ncbi.nlm.nih.gov/7681376/

3. Cefprozil. National Library of Medicine. MedlinePlus. [Revised in January 2022]. [Accessed on 14th August 2024] https://medlineplus.gov/druginfo/meds/a698022.html

4. Sandoz Canada Inc. Cefprozil Tablets (cefprozil as cefprozil monohydrate). Tablets, 250 mg and 500 mg. [Revised in October 2020]. [Accessed on 14th August 2024] https://pdf.hres.ca/dpd_pm/00058690.PDF

5. Central Drugs Standard Control Organisation (CDSCO). Cefprozil tablet & powder for oral suspension. August 2006. Cefprozil 125mg/250mg Dispersible Tablet. June 2004. [Accessed on 14th August 2024] https://cdscoonline.gov.in/CDSCO/Drugs

Useful Diagnostic Tests

• Complete blood count (CBC)