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Introduction About RABEZ D CAPSULE
RABEZ D CAPSULE is a prescription medicine containing rabeprazole and domperidone which helps in managing stomach and duodenal ulcers, gastritis, signs of Gastro-Esophageal Reflux Disease (GERD) such as acid reflux, heartburn, regurgitation (food or acid coming backup in mouth or throat), difficulty in swallowing, sense to cough due to throat discomfort, hoarseness, sore throat, or chest pain due to acid reflux, nausea and bloating.
It can also be used to manage Zollinger-Ellison Syndrome and H.Pylori infections (along with antibiotics). RABEZ D CAPSULE is used as a maintenance therapy to manage symptoms of GERD in patients.
Take RABEZ D CAPSULE at least 30 minutes before meals before a meal for maximum effectiveness. Do not lie down immediately after taking this medicine and follow simple diet with less spice and drink plenty of water or fluids. Before taking this medicine, inform your doctor if you have any liver problems or kidney problems as a precaution.
Consult your doctor before taking this medicine if you are pregnant and breastfeeding women. The most common side effects of taking RABEZ D CAPSULE are nausea, dry mouth, dizziness and diarrhoea. Consult your doctor if any of these side effects trouble you.
Uses Of RABEZ D CAPSULE
- Signs of GERD (such as acidity, heartburn, regurgitation of acid or food, difficulty in swallowing, coughing, hoarseness due to throat discomfort, sore throat)
- Nausea and Bloating
- Stomach ulcers, Duodenal ulcers
- Zollinger-Ellison Syndrome
- H.Pylori infections (when used along with antibiotics)
- Indigestion and improve gut movements
- Gastritis (inflammation of stomach lining)
Benefits of RABEZ D CAPSULE
Effective Relief from Acid Reflux and Heartburn:
RABEZ D CAPSULE helps reduce excessive stomach acid, preventing acid reflux and providing relief from heartburn. It soothes the esophagus, preventing further irritation and discomfort.
Relieves Nausea and Vomiting:
The Domperidone in RABEZ D CAPSULE enhances stomach motility, ensuring food moves efficiently through the digestive system. This helps prevent nausea, vomiting, and the sensation of fullness.
Reduces Bloating and Indigestion:
By improving digestion and preventing stomach acid buildup, RABEZ D CAPSULE alleviates bloating, discomfort, and heaviness after meals, making digestion smoother.
Promotes Faster Digestion and Gut Health:
RABEZ D CAPSULE supports healthy gut function by regulating stomach acid production and improving the movement of food through the digestive tract, ensuring better digestion.
Relieves Symptoms of Gastritis:
This capsule helps heal the stomach lining by reducing acid production and inflammation, relieving gastritis symptoms such as burning pain, nausea, and irritation.
Improves Swallowing and Reduces Throat Irritation:
By preventing acid reflux from reaching the throat, RABEZ D CAPSULE reduces irritation, making swallowing easier and relieving symptoms like sore throat and discomfort.
Fast-Acting Formula for Quick Symptom Relief:
RABEZ D CAPSULE starts working quickly to control acid secretion and improve digestion, providing rapid relief from acidity, reflux, and digestive discomfort.
How RABEZ D CAPSULE Works
RABEZ D CAPSULE contains Rabeprazole and Domperidone, which work together to provide relief from acidity, heartburn, and digestive discomfort.
- Rabeprazole reduces excess stomach acid by blocking acid-producing pumps in the stomach. This helps prevent acid reflux, heartburn, and ulcers.
- Domperidone improves stomach movement, helping food pass through the digestive system smoothly. It prevents nausea, bloating, and a feeling of fullness after meals.
Together, RABEZ D CAPSULE helps in faster digestion, reduces acidity, and reduces discomfort caused by acid reflux or indigestion. It provides quick and long-lasting relief from gastric problems, making you feel better after meals.
How to use RABEZ D CAPSULE
RABEZ D CAPSULE should be taken exactly as prescribed by your doctor. Swallow it whole with a glass of water without crushing or chewing. For best results, take it at the same time each day to maintain consistent acid control.
How to Take RABEZ D CAPSULE
- Take RABEZ D CAPSULE on an empty stomach, preferably 30 minutes before a meal for maximum effectiveness.
- Avoid lying down immediately after taking the capsule, and follow a healthy diet to manage acidity symptoms better.
Recommended Dosage of RABEZ D CAPSULE for Acidity and Reflux
The usual recommended dosage for adults is one capsule daily before breakfast or as directed by a doctor. In severe cases of GERD or acid reflux, your doctor may adjust the dosage based on your condition.
Dosage for Stomach and Duodenal Ulcers
For patients with stomach or duodenal ulcers, one capsule per day is commonly prescribed. The duration of treatment may vary from 4 to 8 weeks, depending on the severity of the ulcer and response to treatment.
RABEZ D CAPSULE Dosage for Children
RABEZ D CAPSULE is generally not recommended for children below 12 years unless prescribed by a doctor. Pediatric dosage, if needed, should be determined based on the child's weight and medical condition.
How Long Should I Take RABEZ D CAPSULE?
The duration of RABEZ D CAPSULE treatment depends on the condition being treated. For short-term relief from acidity and reflux, it may be taken for 2 to 4 weeks. For chronic conditions like GERD or ulcers, the doctor may recommend a longer course of 4 to 8 weeks or more. Always follow your doctor’s advice regarding duration.
What if I forgot to take RABEZ D CAPSULE
If you miss a dose, take it as soon as you remember. However, if it’s close to your next dose, skip the missed one and continue with your regular schedule. Do not take a double dose to make up for the missed one, as it may increase the risk of side effects.
Side Effects Of RABEZ D CAPSULE
Like all medicines, RABEZ D CAPSULE may cause certain side effects in some individuals, although not everybody gets them
Common Side Effects of RABEZ D CAPSULE are:
- Nausea, vomiting, dry mouth
- Dizziness, headache
- Diarrhea, constipation
When To Seek Medical Attention?
Stop taking RABEZ D CAPSULE and contact your doctor immediately if you experience the following side effects:
- severe allergic reaction (sudden wheezing, swelling of lips, face or body, rash, fainting or difficulties swallowing)
- symptoms of liver problems (yellow skin, dark urine and tiredness)
- severe skin reactions such as erythema multiforme, stevens-johnson syndrome or toxic epidermal necrolysis (reddening of skin with blisters or peeling and may be associated with a high fever and joint pains, also severe blisters and bleeding in the lips, eyes, mouth, nose and genitals)
- seizures
- involuntary movements of the face or arms and legs, excessive trembling, excessive muscle stiffness or muscle spasm
- heart rhythm disorders (rapid or irregular heartbeat)
RABEZ D CAPSULE – Longterm Usage and Safety:
- RABEZ D CAPSULE is generally safe for short-term use to manage acidity, GERD, and digestive issues. However, long-term use should be done only under medical supervision, as prolonged use may lead to potential risks such as vitamin B12 deficiency, weakened bones (osteoporosis), kidney issues, or gut imbalances.
- If you need to take RABEZ D CAPSULE for an extended period, your doctor may suggest periodic monitoring and lifestyle modifications to reduce dependence.
- Always follow your doctor’s advice for safe and effective use.
Warning & Precautions
Pregnancy
Monitoring requiredThere are no well controlled studies regarding the use of domperidone and rabeprazole among pregnant women. Animal studies have not indicated any major side effects to the growing fetus. Therefore, RABEZ D CAPSULE should be used in pregnant women only if decided necessary by the physician.
Breastfeeding
Consult your doctorRABEZ D CAPSULE should be used with caution in breastfeeding women, as clinical studies have shown that small amount of domperidone may pass through human breast milk. A risk to the nursing infant cannot be excluded. Therefore, consult your doctor for advice before taking this medicine.
Driving and Using Machines
Use with CautionDo not drive or operate any machines if you experience sleepiness, confusion or less control over your movements.
Alcohol
Consult your doctorAvoid consumption of alcohol while taking RABEZ D CAPSULE, as it could aggravate your existing condition.
Kidney
Use with CautionRABEZ D CAPSULE should be used with caution in patients with kidney patients. Careful monitoring and proper dose adjustments are required in patients who undergo long-term therapy. Therefore, before taking RABEZ D CAPSULE inform your doctor if you have any pre-existing kidney problems.
Liver
Use with CautionRABEZ D CAPSULE should be used with caution in patients with liver patients. Therefore, before taking RABEZ D CAPSULE inform your doctor if you have any pre-existing liver problems.
Allergy
ContraindicatedDo not take RABEZ D CAPSULE if you are allergic to Domperidone or Rabeprazole or any other ingredients of this medicine.
Heart Disease
Use with CautionRABEZ D CAPSULE should be used with caution in patients with heart problems. If you are advised to take this medicine for a long-term therapy, periodic medical consultation are required.
Use In Pediatrics
Consult your doctorThere are no well controlled studies regarding the safety of domperidone and rabeprazole in children (aged below 12 years). Therefore, RABEZ D CAPSULE should be used in children only if considered necessary by your child’s doctor.
Use In Geriatrics
Use with CautionRABEZ D CAPSULE should be used with caution in elderly patients (aged 65 years or above). When consumed as a long-term management therapy, regular check up on bones and overall health is required to avoid long term side effects. Additionally, for elderly patients, doctor may also prescribe bone supplements as a precaution.
Other Warnings for RABEZ D CAPSULE
Before taking RABEZ D CAPSULE, inform your physician if you:
- Have osteoporosis
- Have vitamin B12 deficiency (sore tongue, mouth ulcers, pale skin, depression)
- Are going to test Chromogranin A level
Who should not take [GBNKEYWORD
RABEZ D CAPSULE is not recommended for use in patients suffering from:
- bloody stools or bleeding in the gut
- blockage or tear in the intestines
- severe fluid or electrolyte disturbances
- prolactinoma
- phenylketonuria
- low potassium or magnesium levels or any underlying health conditions that can cause the same
- hereditary problems of galactose intolerance, total lactase deficiency or glucose-galactose malabsorption
Safety Advice
Expert Advice While Taking RABEZ D CAPSULE
- Take on an Empty Stomach: Consume 30 minutes before meals for maximum effectiveness.
- Avoid Spicy & Acidic Foods: Reduce caffeine, alcohol, and fatty foods to enhance results.
- Monitor for Side Effects: Watch for headache, nausea, dizziness, or digestive discomfort and inform your doctor if they persist.
- Do Not Self-Medicate: Long-term use without medical supervision may lead to bone loss, vitamin B12 deficiency, or kidney issues. Therefore, do not self-medicate without doctor consultation.
- Check for Drug Interactions: Inform your doctor about any other medications or supplements to avoid adverse interactions.
Diet and Lifestyle Advice
Lifestyle Changes
- Sleep on Your Left Side – Lying on your left side can help keep stomach acid from traveling up your esophagus.
- Elevate Your Head While Sleeping – Raising the head of your bed by about 6–8 inches can reduce nighttime acid reflux.
- Maintain a Healthy Weight – Excess abdominal fat increases pressure on the stomach, leading to acid reflux.
- Avoid Smoking & Alcohol – Nicotine weakens the lower esophageal sphincter, and alcohol irritates the stomach lining.
- Manage Stress – Stress can worsen acid reflux. Try relaxation techniques such as yoga, meditation, or deep breathing exercises.
- Avoid Tight Clothing – Snug clothing or tight belts can put extra pressure on your stomach, triggering reflux.
Dietary Changes
- Eat Smaller, More Frequent Meals – Large meals put extra pressure on your stomach, increasing the chance of reflux.
- Avoid Eating Late at Night – Stop eating at least 2–3 hours before bedtime.
- Limit Acidic & Spicy Foods – Citrus fruits, tomatoes, spicy foods, and caffeinated beverages can trigger symptoms.
- Choose Low-Fat Dairy – High-fat dairy products may worsen symptoms, while low-fat versions can provide relief.
- Drink Water Instead of Carbonated Beverages – Soda and sparkling water can introduce excess gas into your stomach, increasing reflux.
RABEZ D CAPSULE Vs. Pan-D, Which is better?
| Feature | RABEZ D CAPSULE | Pan-D Capsule |
| Active Ingredients | Rabeprazole (20 mg) + Domperidone (30 mg) | Pantoprazole (40 mg) + Domperidone (30 mg) |
| Acid Reduction Strength | More potent and provides faster relief | Slightly slower onset, but offers long-lasting effect |
| Onset of Action | Works within 1-2 hours | Takes 2-3 hours to start working |
| Duration of Effect | Lasts up to 24 hours | Lasts 24 hours |
| Best For | Severe acidity, ulcers, and GERD needing faster relief | Chronic acid reflux, gastritis, and long-term use |
| Safety in Long-Term Use | May cause bone loss, B12 deficiency, or kidney issues if used for a long time | May lead to electrolyte imbalance or gut issues over prolonged use |
| Doctor’s Preference | Prescribed for rapid symptom relief | Preferred for long-term acid suppression |
Both RABEZ D CAPSULE and Pan-D are effective in treating acidity and reflux, but the choice depends on your doctor's recommendation based on your condition.
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Drug - Drug interaction
- Methotrexate – Can alter its effects, potentially increasing toxicity.
- Antifungals (Ketoconazole, Itraconazole) – Reduced absorption due to altered stomach acid levels.
- HIV Medications (Atazanavir, Nelfinavir, Saquinavir, Rilpivirine) – Decreased effectiveness due to reduced absorption.
- Antacids (Aluminum hydroxide, Magnesium hydroxide) – May reduce the effectiveness of RABEZ D CAPSULE.
- Sucralfate (for ulcers) – Can interfere with absorption.
- Heart Medications (Losartan, Valsartan, Digoxin, Quinidine) – Possible impact on blood pressure and heart rhythm.
- Antibiotics (Clarithromycin, Amoxicillin) – May have interactions that affect antibiotic absorption.
- Blood Thinners (Warfarin) – Increased risk of bleeding.
- Painkillers (Tramadol, Pregabalin) – Potential central nervous system effects.
- Cancer Medications (Erlotinib, Dasatinib, Nilotinib) – Reduced efficacy.
Drug - Food interaction
- Avoid taking RABEZ D CAPSULE with food or milk, as it decreases the effectiveness of the medication. It should ideally be taken 30 minutes before food for optimal absorption.
- Alcohol should be avoided since it can cause dizziness, drowsiness, and impair cognitive function.
- Iron supplements and high-calcium foods may interfere with absorption and should be taken at different times.
Synopsis
| Drug | : | Domperidone, Rabeprazole |
| Pharmacological Category | : | Dopamine antagonist, Proton pump inhibitor |
| Therapeutic Indication | : | Peptic ulcer, GERD |
| Dosage Forms | : | Tablet, Capsule |
FAQs About RABEZ D CAPSULE
Q: What is RABEZ D CAPSULEUsed For?
A: RABEZ D CAPSULE is commonly prescribed for acid reflux, GERD (gastroesophageal reflux disease), heartburn, indigestion, and gastric ulcers. It helps reduce stomach acid production and improves digestion by enhancing gut motility, making it effective in treating gastritis and bloating.
Q: How Does RABEZ D CAPSULE Help with Acid Reflux?
A: RABEZ D CAPSULE contains Rabeprazole and Domperidone, which work together to reduce stomach acid levels and improve food movement in the digestive tract. This helps prevent acid from flowing back into the esophagus, relieving symptoms like heartburn, sour burps, and throat irritation caused by acid reflux.
Q: Can RABEZ D CAPSULE Be Taken for Gastritis?
A: Yes, RABEZ D CAPSULE is often recommended for gastritis as it helps reduce stomach inflammation, control acid secretion, and relieve burning sensation in the stomach. However, it should be taken under medical supervision for the best results.
Q: How Long Should I Take RABEZ D CAPSULE for Acidity?
A: The duration of RABEZ D CAPSULE therapy depends on the severity of acidity and the doctor's recommendation. Generally, it is prescribed for 2 to 4 weeks for mild acid reflux and up to 8 weeks for severe GERD or ulcers. Long-term use should be done only under medical guidance to avoid side effects.
Q: What Are the Benefits of RABEZ D CAPSULE for Stomach Ulcers?
A: RABEZ D CAPSULE helps heal stomach and duodenal ulcers by reducing excessive acid secretion, allowing the ulcer to heal naturally. It also prevents ulcer recurrence and relieves symptoms like burning pain, nausea, and indigestion.
Q: Can RABEZ D CAPSULE Be Taken for Nausea and Vomiting?
A: Yes, RABEZ D CAPSULE is effective in reducing nausea and vomiting caused by acid reflux, bloating, or delayed stomach emptying. Domperidone, one of its ingredients, enhances gut motility and prevents food from staying too long in the stomach.
Q: Is RABEZ D CAPSULE Safe for Long-Term Use in Acid Reflux Treatment?
A: RABEZ D CAPSULE is generally safe for short-term use but long-term use may lead to vitamin B12 deficiency, bone loss, or kidney issues. If long-term treatment is required, periodic monitoring and supplements may be recommended by your doctor.
Q: Can RABEZ D CAPSULE Be Taken on an Empty Stomach?
A: Yes, RABEZ D CAPSULE should be taken on an empty stomach, at least 30 minutes before meals to ensure maximum absorption and effectiveness in controlling acid production.
Q: Should RABEZ D CAPSULE Be Taken Before or After Food?
A: RABEZ D CAPSULE is best taken before food, preferably 30 minutes before breakfast, for optimal acid suppression and symptom relief. Taking it after meals may reduce its effectiveness.
Q: Can I Take RABEZ D CAPSULE at Night for Acid Reflux?
A: RABEZ D CAPSULE is usually taken in the morning before breakfast, but in some cases, doctors may recommend taking it at night before dinner if symptoms persist. Consult your doctor before changing your dose timing.
Q: Can RABEZ D CAPSULE Be Taken with Other Medications Like Antacids?
A: Yes, RABEZ D CAPSULE can be taken with antacids, but it is advisable to take antacids at least 2 hours apart to avoid reducing the effectiveness of Rabeprazole. Consult your doctor before combining medications.
Q: What Are the Common Side Effects of RABEZ D CAPSULE?
A: Common side effects ofRABEZ D CAPSULE include headache, nausea, dizziness, diarrhea, dry mouth, constipation, and bloating. If any of these persist or worsen, seek medical advice.
Q: Does RABEZ D CAPSULE Cause Drowsiness or Dizziness?
A: RABEZ D CAPSULE may cause mild dizziness or drowsiness in some individuals. It is advisable to avoid driving or operating machinery until you know how your body reacts to the medication.
Q: Can RABEZ D CAPSULE Cause Dry Mouth or an Unusual Taste?
A: Yes, dry mouth and altered taste sensation are possible side effects of RABEZ D CAPSULE. Drinking plenty of water and chewing sugar-free gum can help alleviate these symptoms.
Q: Can I Take RABEZ D CAPSULE Daily?
A: Yes, RABEZ D CAPSULE can be taken daily as prescribed by your doctor. However, prolonged daily use without medical supervision is not recommended due to potential long-term side effects.
Q: Is RABEZ D CAPSULE Safe for Acid Reflux?
A: Yes, RABEZ D CAPSULE is highly effective and safe for acid reflux when taken as per the prescribed dosage. It provides quick relief from heartburn, bloating, and regurgitation.
Q: How to Take RABEZ D CAPSULE for Best Results?
A: For the best results, take one capsule on an empty stomach at least 30 minutes before meals, preferably in the morning. Follow your doctor’s dosage instructions carefully.
Q: What Is the Best Time to Take RABEZ D CAPSULE?
A: The best time to take RABEZ D CAPSULE is in the morning before breakfast. If prescribed twice daily, take the second dose before dinner for maximum acid suppression.
Q: Can I Take RABEZ D CAPSULE with Antacids?
A: Yes, but it is recommended to take antacids at least 2 hours apart from RABEZ D CAPSULE to avoid interactions that might reduce its absorption.
Q: Does RABEZ D CAPSULE Interact with Blood Pressure or Diabetes Medications?
A: RABEZ D CAPSULE may interact with certain medications for blood pressure, diabetes, and heart conditions. Always inform your doctor about any existing medications before starting RABEZ D CAPSULE.
Q: Can RABEZ D CAPSULE Be Taken with Alcohol?
A: It is advisable to avoid alcohol while taking RABEZ D CAPSULE as it can increase stomach irritation, worsen acidity, and reduce medication effectiveness.
Q: Is RABEZ D CAPSULE Safe for Pregnant or Breastfeeding Women?
A: RABEZ D CAPSULE should be used in pregnancy and breastfeeding only if prescribed by a doctor. Its safety is not well-established, and alternative treatments may be recommended.
Q: Does RABEZ D CAPSULE Work Immediately or Take Time?
A: RABEZ D CAPSULE starts working within 1-2 hours, but full relief from chronic acidity or ulcers may take a few days to weeks of consistent use.
Q: Does RABEZ D CAPSULE Cause Weight Gain?
A: RABEZ D CAPSULE is not directly linked to weight gain, but prolonged use may alter digestion and metabolism, leading to changes in appetite or mild bloating.
Q: What Should I Eat While Taking RABEZ D CAPSULE?
A: Follow a healthy diet with fiber-rich foods, lean proteins, and probiotics while avoiding spicy, acidic, and fatty foods to improve digestion and prevent acid reflux.
Q: Can RABEZ D CAPSULE Be Used in Pregnant Women?
A: RABEZ D CAPSULE should be taken during pregnancy only if prescribed by a doctor. If necessary, doctors may recommend safer alternatives for managing acid reflux during pregnancy.
References
- Domperidone Rabeprazole Package insert. Corona Remedies Pvt. Ltd. [Accessed on 6th June 2025].
- Rabeprazole Domperidone Capsules. Package insert. Bluecross Labs Ltd. [Revised in February 2023]. [Accessed on 6th June 2025].
- Rabeprazole 10 and 20mg Tablet. EMC. UK. Patient information leaflet. [Revised in March 2017]. [Accessed on 6th June 2025].
- Domperidone. Package insert. Torrent Pharma. [Revised in April 2022]. [Accessed on 6th June 2025].
- Rabeprazole Sodium 20mg + Domperidone 30mg S.R Capsule. Central Drugs Standard Control Organisation. (CDSCO). October 2004. [Accessed on 6th June 2025].
- Pregnancy, breastfeeding and fertility while taking rabeprazole. NHS. UK. [Revised in January 2025]. [Accessed on 6th June 2025].
- Rabeprazole Pregnancy and Breastfeeding Warnings. Drugs.com. [Revised in December 2024]. [Accessed on 6th June 2025].
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