INTRODUCTION

PROVIRONUM 25MG contains Mesterolone which belongs to the group of medicines called Androgens. It is used to manage potency disturbances, male infertility, and male hypogonadism only. Male hypogonadism is a condition when the body does not produce enough testosterone. Testosterone is essential for the development and maintenance of the male reproductive organs as well as other male characteristics such as hair growth, deep voice, sexual drive, muscle mass and body fat distribution. It is for use in male patients only.

PROVIRONUM 25MG is not recommended for use in patients with prostate cancer, male breast cancer, high blood calcium levels, or porphyria. PROVIRONUM 25MG should be used with caution in patients with kidney or heart disease, prostate disease, diabetes, migraine, fits or seizure disorder, abnormal red blood cells or blood disorder, sleep apnoea, etc. Consult your doctor before taking this medicine.

Prior to management with PROVIRONUM 25MG, your doctor may examine your prostate and may advise you to take relevant tests to understand your condition. GBNKEYWORD] is not recommended for use in children and it should be used with caution in elderly patients aged 65 years or above. Consult your doctor before taking PROVIRONUM 25MG. The most common side effects of taking PROVIRONUM 25MG are headache, fluid retention, breast enlargement, increased sexual drive, acne, excess hair growth, premature puberty and stunted growth. Consult your doctor if any of the symptom worsens.

USES OF PROVIRONUM 25MG

Used to manage:

• potency disturbances
• male infertility
• male hypogonadism

HOW PROVIRONUM 25MG WORKS

PROVIRONUM 25MG works similar to the male sex hormone called testosterone. This medicine supplements the male hormone produced by the body. As a result, it helps to manage conditions associated with low testosterone levels in the body.    

DIRECTIONS FOR USE

Take PROVIRONUM 25MG as advised by your physician. Swallow the medicine with a glass of water. Do not crush or chew the medicine. Your physician will decide the correct dose and duration of management and frequency for you depending upon your age, body weight and disease condition. Do not stop taking PROVIRONUM 25MG without contacting your doctor.

SIDE EFFECTS OF PROVIRONUM 25MG

HOW TO MANAGE SIDE EFFECTS

Headache:

Rest and relax. Drink plenty of fluids such as water and electrolytes. Apply a pain-relieving balm on the forehead if necessary. Do not consume alcohol. Consult your doctor if the symptom does not improve.

WARNING & PRECAUTIONS

INTERACTIONS

A. Drug-Drug interactions:

Before taking PROVIRONUM 25MG, inform your doctor if you are taking any of the following medicines:

• phenobarbital and phenytoin (used to manage seizures)  
• cyclosporine (used to suppress the immune system)
• antidiabetics such as metformin, glimepiride or voglibose (used to manage diabetes mellitus)  
• thyroxine (used to manage and replace low thyroid levels)  
• oral anticoagulants such as warfarin (used to manage or prevent blood clots)

Overdosage:

If you or anyone else accidentally take too much of PROVIRONUM 25MG, consult your doctor immediately or visit the nearby hospital. Symptoms of overdosage are liver abnormalities, tumours, changes in blood lipids, increased risk of heart disease, reduced glucose tolerance, decreased testosterone levels, enlargement of male breast tissue, stunted growth, psychiatric disturbances, acute withdrawal syndrome, vomiting blood or blood in stools and tendon damage.

SYNOPSIS

MORE INFORMATION

• Keep PROVIRONUM 25MG out of reach of children
• Store PROVIRONUM 25MG at room temperature

FAQs ABOUT PROVIRONUM 25MG

How does PROVIRONUM 25MG work?

PROVIRONUM 25MG works similar to the male sex hormone called testosterone. This medicine supplements the male hormone produced by the body. As a result, it helps to manage conditions associated with low testosterone levels in the body.

Can I stop taking PROVIRONUM 25MG on my own?

No, it is not recommended to stop taking PROVIRONUM 25MG on your own even though you are feeling well. Continue taking this medicine for as long as your doctor has prescribed, as this may help you to recover completely.

Is PROVIRONUM 25MG safe to use in patients with liver disease?

PROVIRONUM 25MG is not recommended for use in patients with previous or existing liver tumours and should be used with caution in patients with liver disease. Consult your doctor before taking PROVIRONUM 25MG.

What is PROVIRONUM 25MG used for?

PROVIRONUM 25MG is used in adult males to manage potency disturbances, male infertility, and male hypogonadism only. Male hypogonadism is a condition when the body does not produce enough testosterone.

Who should avoid taking PROVIRONUM 25MG?

PROVIRONUM 25MG is not recommended for use in patients with porphyria (inherited blood disorder), prostate cancer, male breast cancer and in patients having high calcium levels in blood. Consult your doctor before taking PROVIRONUM 25MG.

REFERENCES

1. K.D. Tripathi. Androgens and Drugs for Erectile Dysfunction. Essentials of medical pharmacology. Seventh edition. 2013. Page – 299.

2. Giovanni Corona, Giulia Rastrelli, Linda Vignozzi, Mario Maggi. Emerging medication for the management of male hypogonadism. NIH. National Library of Medicine. National center of biotechnology Information. Pubmed.gov. June 2012. [Accessed on 17th June 2022] https://pubmed.ncbi.nlm.nih.gov/22612692/

3. J Gerris, F Comhaire, P Hellemans, K Peeters, F Schoonjans. Placebo-controlled trial of high-dose Mesterolone management of idiopathic male infertility. NIH. National Library of Medicine. National center of biotechnology Information. Pubmed.gov. March 1991. [Accessed on 17th June 2022] https://pubmed.ncbi.nlm.nih.gov/1900485/

4. Central Drugs Standard Control Organisation (CDSCO). Mesterolone. [Accessed on 17th June 2022] https://cdscoonline.gov.in/CDSCO/Drugs

5. Bayer Australia Ltd. Proviron (mesterolone) [Revised in March 2013] [Accessed on 17th June 2022] https://www.nps.org.au/assets/medicines/7a6a6aa4-93f8-4bd2-a23e-a53300feff80.pdf

USEFUL DIAGNOSTIC TESTS

• Follicle Stimulating Hormone
• Testosterone Free
• Testosterone Total