Introduction About PROCILLUS ORAL SUSPENSION

PROCILLUS ORAL SUSPENSION contains Bacillus clausii which belongs to the group of medicines called Probiotics. It important to have good balance of good bacteria in our body. Good bacteria helps to eliminate bad bacteria, to maintain balance. Probiotic supplements are an excellent way to add good bacteria to your body. PROCILLUS ORAL SUSPENSION is used to manage alterations in the intestinal bacterial flora, which can happen due to various conditions like chronic diarrhoea, infection in intestines, lowered immunity, chronic gastrointestinal disorders and antibiotic therapy.

Before taking PROCILLUS ORAL SUSPENSION, inform your doctor if you suffer with bacteremia, septicemia or sepsis in immunocompromised patients or hospitalized due to a serious illness and taking management with antibiotics.

PROCILLUS ORAL SUSPENSION should be used in pregnant and breast-feeding women only if clearly advised by the doctor. PROCILLUS ORAL SUSPENSION can be recommended in children only for shorter duration. Consult your child’s doctor to select an optimal dose for your child.

Inform your doctor if you experience any unusual side effects such as allergic reactions including rash, urticaria and angioedema (swelling underneath the skin) during management with this medicine.

Uses Of PROCILLUS ORAL SUSPENSION

• Manage alteration of the intestinal bacterial flora

How PROCILLUS ORAL SUSPENSION Works

PROCILLUS ORAL SUSPENSION contains Bacillus clausii spores cross the barrier of the acid gastric juices reaching the intestinal tract where they are transformed into metabolically active vegetative cells. It contributes to the recovery of the intestinal microbial flora. Furthermore, since the Bacillus clausii can produce various vitamins, in particular group B vitamins, it contributes to correcting the dysvitaminosis caused by antibiotics and chemotherapeutic agents.

How to use PROCILLUS ORAL SUSPENSION

Take PROCILLUS ORAL SUSPENSION as advised by your physician. Shake the bottle well before use. Take the contents directly or dilute in water or other drinks (like milk or beverages). Once open, the drug should be taken within a short time to avoid contaminating the suspension. Your doctor will decide the correct dose and duration for you depending upon your age, body weight and disease condition.

Warning & Precautions

Pregnancy

PROCILLUS ORAL SUSPENSION should be used in pregnant women only if considered clearly necessary. Consult your doctor before taking it. 

Breastfeeding

PROCILLUS ORAL SUSPENSION should be used in breast-feeding women only if considered clearly necessary. Consult your doctor before taking it.

Driving and Using Machines

 PROCILLUS ORAL SUSPENSION has no influence on the ability to drive and use machines.

Allergy

PROCILLUS ORAL SUSPENSION is not recommended for use if you are allergic to Bacillus clausii or other ingredients of this medicine. 

Interactions

A. Drug-Drug Interactions:

Before taking PROCILLUS ORAL SUSPENSION, inform your doctor if you are taking any medicines including prescription, non-prescription, herbals and vitamin supplements

Overdosage:

If you or anyone else accidentally takes too much of PROCILLUS ORAL SUSPENSION, consult your doctor immediately or go to a nearest hospital straight away.

Synopsis

More Information

• Keep the medicine out of reach of children
• Store PROCILLUS ORAL SUSPENSION at room temperature

FAQs About PROCILLUS ORAL SUSPENSION

Q: What is PROCILLUS ORAL SUSPENSION used for?

A: PROCILLUS ORAL SUSPENSION is used to manage alterations in the intestinal bacterial flora, which can happen due to various conditions like chronic diarrhoea, infection in intestines, lowered immunity, chronic gastrointestinal disorders and antibiotic therapy.

Q: How to take PROCILLUS ORAL SUSPENSION?

A: Take PROCILLUS ORAL SUSPENSION as advised by your physician. Shake the bottle well before use. Take the contents directly or dilute in water or other drinks (like milk or beverages). Once open, the drug should be taken within a short time to avoid contaminating the suspension. Your doctor will decide the correct dose and duration for you depending upon your age, body weight and disease condition.

Q: How does PROCILLUS ORAL SUSPENSION work?

A: PROCILLUS ORAL SUSPENSION contains Bacillus clausii spores cross the barrier of the acid gastric juices reaching the intestinal tract where they are transformed into metabolically active vegetative cells. It contributes to the recovery of the intestinal microbial flora. Furthermore, since the Bacillus clausii can produce various vitamins, in particular group B vitamins, it contributes to correcting the dysvitaminosis caused by antibiotics and chemotherapeutic agents.    

Q: Can PROCILLUS ORAL SUSPENSION be used in children?

A: PROCILLUS ORAL SUSPENSION can be recommended in children only for shorter duration. Consult your child’s doctor for advice to select an optimal dose for your child to manage the specific condition.

Q: What if I forget to take a dose of PROCILLUS ORAL SUSPENSION?

A: If you have missed a dose of PROCILLUS ORAL SUSPENSION, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and take the next scheduled dose. Do not double the dose to make up for the missed one.

References

1. KD. Tripathi. Drugs for Constipation and Diarrhoea. Essentials of medical pharmacology. Seventh edition. 2013. Page – 672-688

2. Princess I, Natarajan T, Ghosh S. When good bacteria behave badly: a case report of Bacillus clausii sepsis in an immunocompetent adult. NIH. National Library of Medicine. National center for biotechnology information. February 2020. [Accessed on 13th September 2022] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7523625/

3. Ianiro G, Rizzatti G, Plomer M, Lopetuso L, Scaldaferri F, Franceschi F, Cammarota G, Gasbarrini A. Bacillus clausii for the Treatment of Acute Diarrhea in Children: A Systematic Review and Meta-Analysis of Randomized Controlled Trials. NIH. National Library of Medicine. National center for biotechnology information. Pubmed Central. August 2018 [Accessed on 13th September 2022] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6116021/

4. Sanofi S.p.A. National Agency for Food and Drug Administration and Control (NAFDAC) [Revised in August 2019] [Accessed on 13th September 2022] https://www.nafdac.gov.ng/wp-content/uploads/Files/SMPC/a_v5/SmPC-Enterogermina-bacillusclausii.pdf

5. Allianz Biosciences Private Limited. Vizylac Junior (Bacillus clausii). Torrent Pharma. [Revised in May 2022]. [Accessed on 13th September 2022] https://www.torrentian.com/pisheet/Upload/PI_Sheet/3085.pdf

6. Sanofi. Enterogermina (Bacillus clausii) Oral Suspension. [Revised in January 2022] [Accessed on 13th September 2022] https://www.sanofi.in/dam/jcr:515d0b20-79a5-4ebd-a594-fa2d172ca5ce/Enterogermina%20OS%20PI.pdf