PREGATRON 150 Capsule 10's
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Introduction About PREGATRON 150 CAPSULE
PREGATRON 150 CAPSULE is used to manage neuropathic pain, peripheral neuropathic pain, fibromyalgia syndrome, peripheral and central neuropathic pain. It contains Pregabalin which belongs to the group of medicines called Anticonvulsants. It can also be used to manage certain forms of epilepsy (fits or seizures) when used in combination with other anti-epileptic medicines. It may also be effective in managing generalized anxiety disorders (severe anxiety that affects daily activities) when other medicines are not effective.
Before taking PREGATRON 150 CAPSULE inform your doctor if you have or had any lung, liver, kidney, or heart problems. You must also inform your doctor before taking the medicine if you have diabetes, any other nerve or brain disorders or if you have a history of drug abuse. Avoid consuming alcohol while taking the medicine as it may make you feel dizzier which can eventually lead to an increased risk of injuries, falls or accidents. Do not take the medicine if you are pregnant or breastfeeding mother. Women of childbearing age must use a suitable contraceptive method to avoid pregnancy while undergoing therapy with the medicine.
PREGATRON 150 CAPSULE should be used with extreme caution in elderly patients (aged above 65 years) particularly in those who have kidney problems. It may alter the blood sugar levels, therefore regularly check your blood sugar levels as a precaution. The most common side are dizziness, drowsiness, headache, dry mouth, blurred vision and swelling of body parts. Contact your doctor if any of these side effects worsen.
Uses Of PREGATRON 150 CAPSULE
It is used to manage:
- neuropathic pain
- peripheral neuropathic pain
- fibromyalgia syndrome
- peripheral and central neuropathic pain
- certain forms of epilepsy
- anxiety disorders
How PREGATRON 150 CAPSULE Works
PREGATRON 150 CAPSULE works by binding to the alpha2-delta subunit of voltage-gated calcium channels, which reduces the release of neurotransmitters and neuronal excitability. It acts as a specific analgesic for peripheral and central neuropathic pain by blocking the transmission of pain signals across the nervous system. It relieves anxiety by reducing the release of certain brain chemicals (GABA) that causes abnormal mood stimulation and anxiety.
How to use PREGATRON 150 CAPSULE
- Take PREGATRON 150 CAPSULE as advised by your physician
- Swallow the medicine with a glass of water. Do not crush or chew the medicine
- It can be taken with or without food
- Your doctor will decide the correct dose and duration of therapy for you depending upon your age, body weight and disease condition
- Do not stop taking the medicine without consulting your doctor
Side Effects Of PREGATRON 150 CAPSULE
Common Side Effects of PREGATRON 150 CAPSULE:
- dizziness, drowsiness, headache
- increased appetite
- elevated mood, confusion, disorientation, irritability
- lack of attention, clumsiness, memory impairment
- tremor, difficulty in speaking
- tingling or numbness, sedation, lethargy
- difficulty in sleeping, tiredness
- visual disturbances
- spinning sensation, problems with balance
- dry mouth, constipation, vomiting, flatulence, diarrhoea, nausea, swelling in the abdomen
- muscle cramps, joint or back pain, pain in limbs
- sore throat
- loss of appetite, weight loss
- heart rate disturbances
- flushing
- difficulty in breathing, dry nose, nasal congestion
- difficult or painful urination
- cold hands and feet
Stop taking PREGATRON 150 CAPSULE and consult your doctor immediately if you experience any of the following side effects:
- serious skin reaction involving reddish non-elevated, target-like, or circular patches on the trunk, often with central blisters, skin peeling, ulcers of mouth, throat, nose, genitals, and eyes (Stevens-Johnson syndrome, toxic epidermal necrolysis)
- yellow discoloration of the skin and whites of the eyes
- self-harming thoughts
Warning & Precautions
Pregnancy
Monitoring requiredPREGATRON 150 CAPSULE is not recommended for use in pregnant women unless considered necessary by the physician. Women of childbearing age must use a suitable contraceptive method (non-hormonal methods) to avoid pregnancy while undergoing therapy with the medicine.
Breastfeeding
Monitoring requiredPREGATRON 150 CAPSULE is not recommended for use in breastfeeding women unless considered necessary by the physician.
Driving and Using Machines
Use with CautionDo not drive or operate any heavy tools or machines if you feel dizzy or sleepy after taking PREGATRON 150 CAPSULE.
Alcohol
Consult your doctorAvoid consumption of alcohol while taking PREGATRON 150 CAPSULE as it could aggravate your dizziness.
Kidney
Use with CautionPREGATRON 150 CAPSULE should be used with caution in patients with kidney diseases (such as decreased urination).
Liver
Use with CautionPREGATRON 150 CAPSULE should be used with caution in patients with severe liver diseases.
Allergy
ContraindicatedDo not take PREGATRON 150 CAPSULE if you are allergic to Pregabalin or to any other ingredients of this medicine.
Lungs
Use with CautionPREGATRON 150 CAPSULE should be used with caution in patients having respiratory problems.
Heart Disease
Use with CautionPREGATRON 150 CAPSULE should be used with caution in patients who have a history of heart disease (Ex. high or low blood pressure).
Use In Pediatrics
ContraindicatedPREGATRON 150 CAPSULE is generally not recommended for use in children and adolescents (aged below 18 years) due to a lack of safety data.
Use In Geriatrics
Use with CautionPREGATRON 150 CAPSULE should be used with caution in elderly patients (aged above 65 years). Proper dose adjustments and careful monitoring are required in such patients.
Others
Before taking PREGATRON 150 CAPSULE, inform your doctor if you:
- have or had constipation
- have a history of drug abuse
Interactions
A. Drug-Drug interactions:
Before taking PREGATRON 150 CAPSULE, inform your doctor if you are taking any of the following medicines such as:
- Strong opioids (Ex. oxycodone)
- Benzodiazepines (Ex. lorazepam)
- Oral contraceptives (Ex. ethinyl estradiol)
Overdosage:
If you or anyone else accidentally took more PREGATRON 150 CAPSULE, consult your doctor immediately or visit the nearby hospital. Symptoms of overdosage might include feeling sleepy, confused, agitated, or restlessness and fits.
Synopsis
| Drug | : | Pregabalin |
| Pharmacological Category | : | GABA analogs |
| Therapeutic Indication | : | Neuropathic pain, Peripheral neuropathic pain, Fibromyalgia syndrome, Peripheral and central neuropathic pain, Certain forms of epilepsy and Anxiety disorders |
| Dosage Forms | : | Tablet, Capsule, Syrup, Oral solution |
More Information
FAQs About PREGATRON 150 CAPSULE
Q: What is PREGATRON 150 CAPSULE used for?
A: PREGATRON 150 CAPSULE is used to manage neuropathic pain, peripheral neuropathic pain, fibromyalgia syndrome, peripheral and central neuropathic pain.
Q: What if I forget to take a dose of PREGATRON 150 CAPSULE?
A: If your forgot to take a dose of PREGATRON 150 CAPSULE, take it as soon as you remember. However, if it is time to take the next dose of this medicine, skip the missed one and take the next dose at regular times. Do not take a double dose of this medicine to compensate for the missed dose.
Q: How long will it take for PREGATRON 150 CAPSULE to reduce nerve pain?
A: The time taken for PREGATRON 150 CAPSULE in managing your condition may vary from person-to-person depending upon the severity of the disease. But you may start noticing the difference from your condition after 2 weeks of using the medicine. However, it may take several weeks for you to experience a complete pain relief. Therefore, take the medicine consistently as advised by your doctor. Do not skip doses or discontinue the therapy in the mid-way without consulting your doctor.
Q: What happens if I stop taking PREGATRON 150 CAPSULE suddenly?
A: Do not stop taking PREGATRON 150 CAPSULE without consulting your doctor as it may precipitate unpleasant withdrawal symptoms (such as headache, difficulty in sleeping, nausea, anxiety, diarrhea, flu-like symptoms, convulsions, nervousness, depression, pain, sweating, and dizziness).
Q: Will taking a higher dose of PREGATRON 150 CAPSULE be more effective?
A: No. Do not take a higher dose of PREGATRON 150 CAPSULE than the prescribed one without consulting your doctor. Taking a higher dose of the medicine may not be beneficial. If the prescribed dose is not effective for you, consult your doctor. Your doctor would prescribe a suitable higher dose for you or suggest an alternative therapy after evaluating your disease condition.
Q: Does PREGATRON 150 CAPSULE help with anxiety?
A: Yes. PREGATRON 150 CAPSULE is used to manage generalized anxiety disorders. It helps to relieve anxiety by reducing the release of certain brain chemicals (GABA) that causes abnormal mood stimulation and anxiety.
Q: What precautions should I need to follow while taking PREGATRON 150 CAPSULE?
A: Before taking the medicine inform your doctor if you have or had any lung, liver, kidney, or heart problems. You must also inform your doctor before taking the medicine if you have diabetes, any other nerve or brain disorders or if you have a history of drug abuse. Women of childbearing age must use a suitable contraceptive method to avoid pregnancy while undergoing therapy with the medicine.
Q: Can PREGATRON 150 CAPSULE be used in children?
A: PREGATRON 150 CAPSULE is generally not recommended for use in children and adolescents (under 18 years of age) due to lack of clinical safety data.
Q: Can PREGATRON 150 CAPSULE cause a headache after taking it?
A: Yes. Headache is a common side effect of taking the medicine. In case if you are experiencing a headache after taking the medicine, try to rest and relax. Keep drinking plenty of fluids such as water or electrolytes. Apply a pain-relieving balm on the forehead if needed. Do not consume too much of alcohol.
References
1. K.D. Tripathi. Antiepileptic Drugs. Essentials of medical pharmacology. Seventh edition. 2013. Page – 420.
2. Charles P Taylor, Timothy Angelotti, Eric Fauman. Pharmacology and mechanism of action of pregabalin: the calcium channel alpha2-delta (alpha2-delta) subunit as a target for antiepileptic drug discovery. NIH National Library of Medicine, National center for biotechnology information. Pubmed.gov. February 2007. [Accessed on 7th April 2022] click here
3. Vivek Verma, Nirmal Singh, Amteshwar Singh Jaggi. Pregabalin in Neuropathic Pain: Evidence and Possible Mechanisms. NIH National Library of Medicine, National center for biotechnology information. Pubmed.gov. January 2014. [Accessed on 7th April 2022] click here
4. Milpharm Limited. Electronic Medicines Compendium (EMC). [Revised in March 2022] [Accessed on 7th April 2022] click here
5. Parke Davis. U.S. Food & Drug Administration. [Revised in September 2017] [Accessed on 7th April 2022] click here
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