Introduction About POWERGYL SUSPENSION
POWERGYL SUSPENSION is a combination of Metronidazole and Ofloxacin, which belong to the group of medicines called Antibiotics. POWERGYL SUSPENSION is used to manage different kinds of bacterial and parasitic infections (caused by different kinds of bacteria or parasites), diarrhea (loose, watery stools that occur more often than usual) and systemic infection (an infection that is in the bloodstream).
POWERGYL SUSPENSION should be used with caution in patients with liver problems, kidney problems and heart disease. POWERGYL SUSPENSION is not recommended for use by pregnant or breastfeeding women. Consult your doctor before taking it.
The most common side effects of POWERGYL SUSPENSION are nausea, headache, sleeplessness, genital itching in women, dizziness, vaginal inflammation, diarrhoea and vomiting. Consult your doctor if any of the symptoms worsen.
Uses Of POWERGYL SUSPENSION
- Manage bacterial and parasitic infections
- Manage diarrhea
- Manage systemic infection (an infection that is in the bloodstream)
How POWERGYL SUSPENSION Works
POWERGYL SUSPENSION helps to reduce infections caused by different bacteria or parasites, whereas Metronidazole works by inhibiting the protein synthesis in the cells of various bacteria and parasites, which gradually leads to cell death. Ofloxacin works by managing bacterial growth (DNA replication), which leads to cell death.
How to use POWERGYL SUSPENSION
Always use POWERGYL SUSPENSION as directed by your physician. Shake well before use. Do not stop using POWERGYL SUSPENSION without informing your doctor.
Side Effects Of POWERGYL SUSPENSION
Common
- nausea
- headache
- sleeplessness
- genital itching in women
- dizziness
- vaginal inflammation
- diarrhoea
- vomiting
Rare
Stop using POWERGYL SUSPENSION and contact your doctor immediately if you have:
- allergic reaction with symptoms such as swelling of the face, lips, throat or tongue, itching, difficulty breathing, difficulty swallowing
- skin rashes with blistering, peeling or bleeding of the skin around the lips, eyes, mouth, nose and genitals
- serious but very rare side effect is a brain disease (encephalopathy)
- blistering or bleeding of the skin around the eyes, mouth, lips, nose and genitals
- red, scaly widespread rash with bumps under the skin and blisters accompanied by fever
- steven johnson syndrome - severe blistering rash where layers of the skin may peel off
How To Manage Side Effects
Nausea / Vomiting:
Take this medicine with or just after meals. Stick to simple meals. Avoid eating oil-rich or spicy foods. Consult your doctor if the symptom does not improve.
Headache:
Rest and relax. Drink plenty of fluids such as water or electrolytes. Apply a pain-relieving balm on the head if required. Do not consume alcohol. Consult your doctor if the symptom does not improve.
Dizziness:
If you feel dizzy, keep your eyes closed sit or lie down. Do not drive or operate machinery. Consult your doctor if the symptom does not improve.
Diarrhea:
Drink lots of fluids, such as water or fruit juices to keep yourself hydrated. Avoid taking any medicine on your own for managing diarrhoea. Consult your doctor if the symptom does not improve.
Warning & Precautions
Pregnancy
POWERGYL SUSPENSION is not recommended for use in pregnant women. Consult your doctor before using it.
Breastfeeding
POWERGYL SUSPENSION is not recommended for use in breastfeeding women. Consult your doctor before using it.
Driving and Using Machines
Do not drive or operate any machines if you feel sleepy or dizzy or could affect your eyesight after using POWERGYL SUSPENSION. Consult your doctor before using it.
Alcohol
Avoid consumption of alcohol while taking POWERGYL SUSPENSION because it might cause unpleasant side effects such as nausea, vomiting, hot flushes, stomach pain, very fast or uneven heartbeat and headache. Consult your doctor before using it.
Kidney
POWERGYL SUSPENSION should be used with caution in patients with kidney problems and patients undergoing kidney dialysis. Consult your doctor before using it.
Liver
POWERGYL SUSPENSION should be used with caution in patients with liver problems. Consult your doctor before using it.
Allergy
Do not take POWERGYL SUSPENSION if you are allergic to metronidazole, ofloxacin, other quinolone antibiotics such as ciprofloxacin or norfloxacin or any of the other ingredients in this medicine. Consult your doctor before using it.
Lungs
POWERGYL SUSPENSION should be used with caution in patients with a lung transplant. Consult your doctor before using it.
Heart Disease
POWERGYL SUSPENSION should be used with caution in patients with heart disease. Consult your doctor before using it.
Others
Before using POWERGYL SUSPENSION, inform your doctor if you:
- have a disease of the nervous system
- are on hemodialysis
- have a history of joint problems or rheumatoid arthritis
- are suffering from Alzheimer’s disease, seizures, stroke
- have decreased in blood minerals
Use in Pediatrics:
POWERGYL SUSPENSION should be used with caution in children. Consult your doctor before using it.
Use in Geriatrics:
POWERGYL SUSPENSION should be used with caution. Consult your doctor before using it.
Interactions
A. Drug-Drug interactions:
Before taking POWERGYL SUSPENSION, inform your doctor if you are taking any of these medicines:
- warfarin (anticoagulants)
- lithium (used to manage mental illness)
- phenytoin, carbamazepine, phenobarbitone (used to manage epilepsy)
- 5 fluorouracil, busulfan (used to manage cancer)
- ciclosporin (immunosuppressant)
- disulfiram
Overdosage:
If you or anyone else accidentally receive too much of POWERGYL SUSPENSION, consult your doctor immediately or visit the nearby hospital.
Synopsis
| Drug | : | Metronidazole, Ofloxacin |
| Pharmacological Category | : | Nitroimidazole antibiotic, Quinolone antibiotic |
| Therapeutic Indication | : | Bacterial and parasitic infections, diarrhea, systemic infection |
| Dosage Forms | : | Tablet, Syrup, Suspension, Oral Suspension |
More Information
- Keep POWERGYL SUSPENSION out of reach from children
- Store at room temperature
FAQs About POWERGYL SUSPENSION
Q: What is POWERGYL Suspension used for?
A: POWERGYL Suspension is commonly used to manage bacterial and protozoal infections in various parts of the body, including the gastrointestinal tract, urinary tract and reproductive organs, etc.
Q: How do POWERGYL Suspension work?
A: POWERGYL Suspension is a combination of two medicines, namely ofloxacin and metronidazole. Ofloxacin is a broad-spectrum antibiotic that inhibits the growth of bacteria by interfering with their DNA replication. Metronidazole is an antibiotic and antiprotozoal medication that works by disrupting the DNA structure of bacteria and parasites, leading to their death.
Q: What types of infections are managed with POWERGYL Suspension?
A: POWERGYL Suspension are commonly used to manage infections such as bacterial diarrhea, urinary tract infections (UTIs), pelvic inflammatory disease (PID), bacterial vaginosis, and certain types of skin infections.
Q: How should I take POWERGYL Suspension?
A: POWERGYL Suspension are usually taken orally with a full glass of water. It's important to follow the dosage instructions provided by your healthcare provider and to complete the full course of management, even if symptoms improve before the medication is finished.
Q: Can I drink alcohol while taking POWERGYL Suspension?
A: It is generally recommended to avoid alcohol while taking Metronidazole, as it can cause severe nausea, vomiting, headache, and flushing. However, Ofloxacin does not typically interact with alcohol.
Q: What are the common side effects of POWERGYL Suspension?
A: Common side effects of taking POWERGYL Suspension may include nausea, vomiting, diarrhea, stomach pain, dizziness, headache, and changes in taste. If any of these side effects persist or worsen, it's important to consult your healthcare provider.
Q: Can POWERGYL Suspension be used during pregnancy?
A: POWERGYL Suspension are generally not recommended during pregnancy, especially during the first trimester, due to potential risks to the developing fetus. However, your healthcare provider may prescribe them if the benefits outweigh the risks.
Q: Is POWERGYL Suspension safe for pediatric use?
A: POWERGYL Suspension may be prescribed for pediatric use under the guidance of a healthcare provider. The dosage and duration of management will be determined based on the child's age, weight, and the severity of the infection.
Q: How long does it take for POWERGYL Suspension to start working?
A: The time it takes to see improvement in symptoms varies depending on the type and severity of the infection. In some cases, symptoms may improve within a few days of starting management, but it's important to complete the full course of antibiotics as prescribed by your healthcare provider to ensure the infection is fully managed.
Q: Can breast-feeding women take POWERGYL Suspension?
A: A few clinical trial studies show that POWERGYL Suspension passes through the breast milk from mother to infant while breastfeeding. So, POWERGYL Suspension is not recommended for breastfeeding women. Consult your doctor before taking the medicine.
Q: I am presently undergoing kidney dialysis. Can I take POWERGYL Suspension?
A: POWERGYL Suspension should be used with caution in dialysis patients. Since dialysis purifies intoxicants and other materials in the blood, POWERGYL Suspension can also be removed. So, the effect of POWERGYL Suspension might be reduced. It is better to inform your doctor if you are on dialysis and you are taking POWERGYL Suspension.
References
1. KD Tripathi, Anti-microbial drugs and Beta-lactam Antibiotics, Essentials of medical pharmacology, Seventh edition. 2013 Page 894 & 713.
2. Connor B. Weir; Jacqueline K. Le., Metronidazole, National Library of Medicine. [Revised April 2022] [Accessed 22 June 2022] https://www.ncbi.nlm.nih.gov/books/NBK539728/
3. JB Chemicals, OFM SUSP, CIMS. [Accessed 22 June 2022] https://www.mims.com/india/drug/info/ofm%20susp
4. Rosemont, Metronidazole. [Revised April 2020] [Accessed 22 June 2022] https://www.medicines.org.uk/emc/files/pil.6690.pdf
5. Medindia, Ofloxacin. [Accessed 22 June 2022] https://www.medindia.net/drug-price/ofloxacin/zo-60ml.htm#Indication
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