Introduction About POLO 250 SUSPENSION

POLO 250 SUSPENSION contains Paracetamol which belongs to the group of medicines called Analgesics and Antipyretics. It is used to relieve mild to moderate pain like headache, migraine, nerve pain, toothache, sore throat, period pains, teething, immunisation, earache, and general aches and pains. It can also be used to manage fever (high temperature), and symptoms of cold or flu.

Before taking POLO 250 SUSPENSION, inform your doctor if you have liver or kidney problems, fructose intolerance, Gilberts syndrome, glucose-6-phosphate dehydrogenase deficiency, hemolytic anaemia, reduced glutathione levels, malnourishment, dehydration or if you weigh less than 50 kg.

POLO 250 SUSPENSION should be used in pregnant women only if considered necessary. Avoid consumption of alcohol during management with POLO 250 SUSPENSION, as it might make you more prone to side effects.

POLO 250 SUSPENSION is not recommended for use in children (2-3 months old, weighing less than 4 kg or born before 37 weeks). Contact your doctor if you get any side effects of any of the symptoms get worse.

Uses Of POLO 250 SUSPENSION

• Relieves mild to moderate pain, fever, and symptoms of cold or flu

How POLO 250 SUSPENSION Works

POLO 250 SUSPENSION relieves pain by increasing the pain threshold by inhibiting certain enzymes (COX-1 and COX-2) involved in synthesis of chemicals responsible for inducing pain (prostaglandins). It reduces fever by directly acting on heat-regulating centers in the brain, resulting in vessel relaxation, sweating, and loss of body heat.

How to use POLO 250 SUSPENSION

Take POLO 250 SUSPENSION as advised by your physician. Shake well before use. Your doctor will decide the correct dose and duration for you based upon your age, body weight and disease condition.

Side Effects Of POLO 250 SUSPENSION

How To Manage Side Effects

Constipation

Eat plenty of fiber rich foods like fresh fruits, vegetables, cereals, and drink plenty of water. Exercise more regularly. If you still feel constipated, contact your doctor.

Nausea And Vomiting

Take POLO 250 SUSPENSION with, or just after meals. Stick to simple meals. Avoid eating oily or spicy foods. If you still feel nauseous and vomiting, contact your doctor.

Skin rash Or Itching

Avoid hot showers because hot water can irritate your skin more. Do not scratch the affected area. Use protective clothing when going outdoors. Regularly moisturize your skin. Consult your doctor if your skin rash gets worse.

Warning & Precautions

Pregnancy

Monitoring required

POLO 250 SUSPENSION should be used in pregnant women only if considered necessary. Consult your doctor before taking it.

Breastfeeding

Monitoring required

POLO 250 SUSPENSION should be used in breastfeeding women only if considered necessary. Consult your doctor before taking it.

Driving and Using Machines

Use with Caution

Consult your doctor if you feel any side effect during management with POLO 250 SUSPENSION that may stop you from driving or using machines.

Alcohol

Consult your doctor

Avoid consumption of alcohol while taking POLO 250 SUSPENSION. Before taking POLO 250 SUSPENSION, inform your doctor if you have chronic alcoholism.

Kidney

Use with Caution

POLO 250 SUSPENSION should be used with caution in patients with severe kidney problems. Consult your doctor before taking it.

Liver

Use with Caution

POLO 250 SUSPENSION should be used with caution in patients with severe liver problems, liver problems due to excessive alcohol intake, or have Gilberts syndrome (liver doesn't process bilirubin properly). Consult your doctor before taking it.

Allergy

Contraindicated

Do not take POLO 250 SUSPENSION if you are allergic to Paracetamol or any of the other ingredients of this medicine.

Interactions

A. Drug-Drug interactions:

Before taking POLO 250 SUSPENSION, inform your doctor if you are taking any of the following medicines:

• medicines used to induce sleep (Ex. phenobarbital, pentobarbital)
• medicines used in depression (Ex. amitriptyline, nortriptyline)
• cholestyramine (used to control blood fat levels)
• warfarin (used for managing blood clots)
• zidovudine (used to manage HIV infection)
• other medicines containing paracetamol
• medicines to manage nausea and vomiting (Ex. metoclopramide, domperidone)
• medicines used to manage fits (Ex. carbamazepine, phenytoin)
• medicines used to manage pregnancy (Ex. ethinyl estradiol, norethindrone)
• medicines used to manage bacterial infections (Ex. flucloxacillin, chloramphenicol)

Overdosage:

If you, your child, or anyone else accidentally take too much of POLO 250 SUSPENSION, consult your doctor immediately or visit the nearby hospital. Symptoms of POLO 250 SUSPENSION overdose are delayed, serious liver damage, paleness, nausea, sweating, vomiting, loss of appetite and stomach pain.

Synopsis

More Information

• Keep POLO 250 SUSPENSION out of reach of children
• Store below 25°C

FAQs About POLO 250 SUSPENSION

Q: Can POLO 250 SUSPENSION be given to children?

A: POLO 250 SUSPENSION is not recommended for use in children (2-3 months old, weighing less than 4 kg or born before 37 weeks). Your doctor will decide the correct dose or select a suitable alternative management for your child.

Q: What if I forget to take a dose of POLO 250 SUSPENSION?

A: If you forget to take a dose of POLO 250 SUSPENSION, take it as soon as you remember. However, omit the missed dose if it's almost time for the next one. Do not take POLO 250 SUSPENSION two times to make up for the missed dose.

Q: Can POLO 250 SUSPENSION manage pregnancy?

A: No. POLO 250 SUSPENSION does not manage pregnancy, but it should be used with caution in fertile women. Consult your doctor before taking it.

Q: Can POLO 250 SUSPENSION be stopped?

A: Continue taking POLO 250 SUSPENSION until your doctor tells you to stop, unless you experience any unwanted effects, worsening of your condition or any new symptoms. Contact your doctor in such case.

Q: What is POLO 250 SUSPENSION used for?

A: POLO 250 SUSPENSION is used to relieve mild to moderate pain like headache, migraine, nerve pain, toothache, sore throat, period pains, teething, immunisation, earache, and general aches and pains. It can also be used to manage fever (high temperature), and symptoms of cold or flu.

Q: What should I tell my doctor before taking POLO 250 SUSPENSION?

A: Patients taking POLO 250 SUSPENSION must inform their doctor about their pre-existing conditions like kidney or liver problems, or any type of sugar intolerance. Patients should also tell if they are pregnant, breast-feeding, or allergic to anything. Consult your doctor if you experience anything different.

Q: Can POLO 250 SUSPENSION be taken in pregnancy?

A: POLO 250 SUSPENSION should be used in pregnant women only if considered necessary. The lowest possible dose that reduces your pain and/or your fever should be used for the shortest time possible. Contact your doctor if the pain or fever is not relieved or if you need to take the medicine more often. If you are pregnant, think you may be pregnant or are planning to get pregnant, consult your doctor before taking it.

Q: Can I take other medicines with POLO 250 SUSPENSION?

A: Before taking POLO 250 SUSPENSION, inform your doctor if you are taking, have taken, or might take any other medicine, including prescription, over the counter or any herbal medicine, as these might cause serious side effects by interacting with each other.

References

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2. KD. Tripathi. NSAIDs and Antipyretic-Analgesics. Essentials of Medical Pharmacology. Seventh edition. 2013. Page – 206.

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4. Okereke, B., Ibeleme, O., & Bisi-Onyemaechi, A. Randomised comparative trial of the efficacy of paracetamol syrup and dispersible tablets for the management of fever in children. NIH National Library of Medicine, National center for biotechnology information. PubMed Central. March 2021. [Accessed on 13th August 2022] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7985941/

5. Rosemont Pharmaceuticals Ltd. Electronic Medicines Compendium (EMC). [Revised in May 2022] [Accessed on 13th August 2022] https://www.medicines.org.uk/emc/files/pil.6694.pdf

6. Delpharm Orleans. Electronic Medicines Compendium (EMC). [Revised in May 2022] [Accessed on 13th August 2022] https://www.medicines.org.uk/emc/files/pil.6634.pdf

7. Rosemont Pharmaceuticals Ltd. Electronic Medicines Compendium (EMC). [Revised in July 2021] [Accessed on 13th August 2022] https://www.medicines.org.uk/emc/files/pil.2853.pdf

8. Micro Labs Ltd. Paracetamol. [Accessed on 13th August 2022] https://www.microlabsltd.com/elibrary/node/1782, https://www.microlabsltd.com/elibrary/node/1787, https://www.microlabsltd.com/elibrary/node/1797, https://www.microlabsltd.com/elibrary/node/1800

9. GlaxoSmithKline Asia Private Limited. Paracetamol. [Accessed on 13th August 2022] https://www.crocin.com/products/children-products/5-to-12-years/crocin-suspension-ds.html#