Introduction About PIROX GEL

PIROX GEL contains Piroxicam, which belongs to the group of medicines called Non-Steroidal Anti-Inflammatory Drugs. It is used for the management of rheumatism (an autoimmune disease causing painful swelling of joints and stiffness), sprains (ligament tear with limited movements, popping sensation or sound and bruising), strains and mild osteoarthritis (a joint disease that occurs when the protective tissues at the end of the bones wear done which is characterised by joint pain in hands, neck and hip).

Piroxicam exerts its anti-inflammatory actions by inhibiting the enzyme cyclooxygenase-1 thereby, blocking the release of prostaglandins (a substance produced during injury and inflammation causing pain and swelling) and other chemical mediators that cause pain and swelling.

PIROX GEL should be used with caution in patients with kidney disease. Consult your doctor for advice. It should be used with caution during breastfeeding. PIROX GEL is not recommended for use in children below 12 years of age. Consult your doctor for advice. Side effects of this medicine are nausea (feeling sick), indigestion, and stomach discomfort. Contact your doctor if the symptom does not improve.

Uses Of PIROX GEL

• Manage rheumatism (pain or swelling in or around the bones, muscles, or joints), sprains, strains, and mild osteoarthritis of joints like knees, wrists, ankles etc

How PIROX GEL Works

PIROX GEL exerts its anti-inflammatory actions by inhibiting the enzyme cyclooxygenase-1 thereby, blocking the release of prostaglandins (a substance produced during injury and inflammation causing pain and swelling) and other chemical mediators that cause pain and swelling.

How to use PIROX GEL

Always use this medicine exactly as your doctor has told you. Apply as advised by your doctor. Rub the gel into the skin gently until the gel disappears.

Side Effects Of PIROX GEL

How To Manage Side Effects

Nausea or Vomiting:

Stick to simple meals. Try to avoid oil-rich or spicy foods, sugary snacks, and drinks. Try to drink liquid slowly along with your meals, or in between meals. Consult your doctor if your symptom is not improving.

Skin rash:

Try to avoid hot showers because they may cause skin irritation. Avoid frequent contact and rubbing over the affected area. Use sunscreen and protective clothing when outdoors. If this symptom does not get better, speak to a doctor.

Warning & Precautions

Pregnancy

PIROX GEL is not recommended for use in pregnant women, especially during the last three months of pregnancy. Consult your doctor before taking this medicine.

Breastfeeding

PIROX GEL should be used with caution in breastfeeding women. Discuss the risks and benefits with your doctor.

Driving and Using Machines

PIROX GEL does not affect the ability to drive or operate machinery. However, consult your physician.

Kidney

PIROX GEL should be used with caution in patients with kidney disease. Consult your doctor for advice.

Allergy

Do not take PIROX GEL if you are allergic to Piroxicam.

Interactions

A. Drug-Drug interactions:

Before using PIROX GEL inform your doctor if you are taking any prescription, non-prescription or herbal medicines.

Overdosage:

If you or anyone else accidentally swallowed too much of PIROX GEL, consult your doctor immediately or visit the nearby hospital.

Synopsis

More Information

• Keep out of reach from children
• Store in a dry place below 25°C

FAQs About PIROX GEL

What are the uses of PIROX GEL?

PIROX GEL It is used for the management of rheumatism (pain or swelling in or around the bones, muscles, or joints), sprains, strains, and mild osteoarthritis of joints like knees, wrists, ankles etc.

How does PIROX GEL works?

PIROX GEL exerts its anti-inflammatory actions by inhibiting the enzyme cyclooxygenase-1 thereby, blocking the release of prostaglandins (a substance produced during injury and inflammation causing pain and swelling) and other chemical mediators that cause pain and swelling.

Can PIROX GEL be given to children?

PIROX GEL is not recommended for use in children below 12 years of age. Your doctor may prescribe you any other suitable medication. Consult your doctor for advice.

How to use PIROX GEL?

Always use this medicine exactly as your doctor has told you. Apply as advised by your doctor. Rub the gel into the skin gently until the gel disappears.

Can PIROX GEL be used in a pregnant woman?

PIROX GEL is not recommended for use in pregnant women, especially during the last three months of pregnancy.  Consult your doctor for advice before using [GBNKEYEORD].

References

1. KD Tripathi. Non-steroidal anti-inflammatory drugs. Essentials of medical pharmacology. Eighth edition. 2013. Page – 218.

2. R N Brogden, R C Heel, T M Speight, G S Avery; Piroxicam: a review of its pharmacological properties and therapeutic efficacy. NIH National Library of Medicine, National centre for biotechnology information. PubMed.gov. September 1981. [Accessed 28th July 2022] https://pubmed.ncbi.nlm.nih.gov/7021122/                       

3. Gunesh Dhembre. Formulation and critical evaluation of piroxicam gel. ResearchGate. February 2021. [Accessed 28th July 2022] https://www.researchgate.net/publication/353379377_Formulation_and_critical_evaluation_of_piroxicam_gel                                                                   

4. Tiofarma B.V. Electronic Medicines Compendium (EMC). [Revised in February 2022] [Accessed 28th July 2022] https://www.medicines.org.uk/emc/files/pil.5047.pdf