Introduction About PHENSEDYL DX SYRUP

PHENSEDYL DX SYRUP is a combination of Chlorpheniramine and Dextromethorphan which belongs to the group of medicines called Antihistamines and Antitussives respectively. It is used to relieve dry cough due to throat irritation, sneezing and running nose. It is also used to manage hay fever or upper respiratory allergies such as sneezing, runny nose, itchy, watery eyes, itching of the nose and throat.

Avoid consumption of alcohol while taking this medicine as this may lead to unwanted effects.  PHENSEDYL DX SYRUP is not recommended for use in patients with or at risk of developing, respiratory failure (Ex. chronic obstructive airways disease or pneumonia, or an exacerbation of asthma). PHENSEDYL DX SYRUP should be used with caution in patients with lung disease, severe kidney or heart diseases. PHENSEDYL DX SYRUP is not recommended for use in pregnant or breastfeeding women. Contact your doctor before taking.

PHENSEDYL DX SYRUP is not recommended for use in children under 2 years of age. Contact your doctor before taking. PHENSEDYL DX SYRUP should be used with caution in elderly patients (aged 65 years or above). Contact your doctor before taking. The most common side effects of this medicine are sedation, somnolence, disturbance in attention, abnormal coordination, dizziness, drowsiness, headache, blurred vision, nausea, vomiting, dry mouth, abdominal discomfort, fatigue. Contact your physician if any of the symptoms worsen.

Uses Of PHENSEDYL DX SYRUP

• Used to manage dry cough due to throat irritation, sneezing and running nose

How PHENSEDYL DX SYRUP Works

PHENSEDYL DX SYRUP helps to manage dry cough, where Chlorpheniramine is an antihistamine which works by blocking the histamine H1 receptor and manages the release of histamine (which normally produces symptoms of sneezing, itching, watery eyes, and runny nose) and Dextromethorphan is a cough suppressant which relieves cough by acting on the cough centre in the brain. Together relives cough effectively.

How to use PHENSEDYL DX SYRUP

Take PHENSEDYL DX SYRUP as advised by your physician. Shake well before use. Your physician will decide the correct dose and duration for you depending upon your age, body weight and disease condition.

Side Effects Of PHENSEDYL DX SYRUP

How To Manage Side Effects

Dizziness Or Drowsiness

Try to rest and relax. Get enough sleep. Avoid driving or operate any machines while you are feeling dizzy. Do not consume alcohol, as it can aggravate your dizziness. Contact your doctor if dizziness persists.

Headache

Rest and relax. Drink plenty of fluids such as water and electrolytes. Apply a pain-relieving balm on the head if necessary. Do not consume alcohol. Contact your doctor if your headache did not improve.

Nausea And Vomiting

Take this medicine with, or just after meals. Stick to simple meals. Avoid eating oily or spicy foods. Contact your doctor if nausea or vomiting bothers you.

Stomach Pain

Try to rest and relax. Eat small meals but take frequently. Keep a heat pad on your stomach. Contact your doctor if the stomach pain worsens.

Warning & Precautions

Pregnancy

Contraindicated

PHENSEDYL DX SYRUP is generally not recommended for use in pregnancy. Contact your doctor before taking the medicine.

Breastfeeding

Contraindicated

PHENSEDYL DX SYRUP is not recommended for use in breastfeeding women as it may pass through the breast milk. Contact your doctor before taking.

Driving and Using Machines

Use with Caution

Do not drive or operate any machines if you feel drowsiness, dizziness, blurred vision, and psychomotor impairment after taking PHENSEDYL DX SYRUP.

Alcohol

Consult your doctor

Avoid consumption of alcohol while taking PHENSEDYL DX SYRUP as it may lead to unwanted effects.

Kidney

Use with Caution

PHENSEDYL DX SYRUP should be used with caution in patients with severe kidney disease. Contact your doctor before taking.

Liver

Use with Caution

PHENSEDYL DX SYRUP should be used with caution in patients with severe liver disease. Contact your doctor before taking.

Allergy

Contraindicated

Do not take PHENSEDYL DX SYRUP if you are allergic to Chlorpheniramine, Dextromethorphan, or to other ingredients of this medicine.

Lungs

Consult your doctor

PHENSEDYL DX SYRUP is not recommended for use in patients with or at risk of developing, respiratory failure (Ex.  chronic obstructive airways disease or pneumonia, or an exacerbation of asthma). It should be used with caution in patients with asthma, bronchitis, bronchiectasis, emphysema. Contact your doctor before taking.

Heart Disease

Use with Caution

PHENSEDYL DX SYRUP should be used with caution in patients with severe heart diseases and severe hypertension. Contact your doctor before taking.

Use In Pediatrics

Consult your doctor

Your doctor will prescribe the right dose depends on your child’s age, body weight and disease condition. Contact your doctor before taking PHENSEDYL DX SYRUP.

Use In Geriatrics

Use with Caution

PHENSEDYL DX SYRUP should be used with caution in elderly patients (aged 65 years or above). Contact your doctor before taking the medicine.

Interactions

A. Drug-Drug interactions:

Inform your physician, if you are taking any of the following medicines,

• alprazolam, diazepam, lorazepam (medicines that induces sleep and to manage anxiety)
• phenobarbital, pentobarbital (medicines used to reduce excitement)
• tramadol, morphine, codeine, methadone (medicines used for severe pain)
• fluphenazine, thioridazine, haloperidol, perphenazine (medicines used to manage psychoses)
• dicyclomine (medicines used to relax stomach and intestine)
• fluoxetine, paroxetine, sertraline, amitriptyline, imipramine, selegiline, rasagiline, bupropion (medicines used for depression)
• cough and cold medicines
• phenytoin (medicine used to manage fits)
• quinidine, amiodarone, propafenone, and flecainide (used to manage heart rhythm disorders)
• cinacalcet (used to manage hyperparathyroidism)
• terbinafine (used to manage fungal infections)
• dimenhydrinate (used to manage the symptoms of allergic reactions)

Overdosage:

If you or anyone else accidentally took too much of this medicine, consult your doctor immediately. Symptoms of overdosage are drowsiness, lethargy, nystagmus, ataxia, depression, nausea, vomiting, and hyperactivity, excitation, mental confusion, tremors, psychosis, hallucinations, high fever and convulsions, restlessness, nervousness and irritability, stupor, dystonia, and respiratory depression.

Synopsis

More Information

• Keep out of reach of children
• Store PHENSEDYL DX SYRUP below 30°C

FAQs About PHENSEDYL DX SYRUP

Q: What is PHENSEDYL DX SYRUP used for?

A: PHENSEDYL DX SYRUP is used to manage cough due to throat or bronchial irritation, sneezing and running nose caused by cold, dry cough, allergic cough, post-operative cough, smokers cough, and night-time cough. It is also used to manage hay fever or upper respiratory allergies such as sneezing, runny nose, itchy, watery eyes, and itching of the nose and throat. Contact your doctor before taking.

Q: How does PHENSEDYL DX SYRUP work?

A: PHENSEDYL DX SYRUP helps to manage cough, where chlorpheniramine is an antihistamine that works by blocking the histamine H1 receptor and managing the release of histamine (which normally produces symptoms of sneezing, itching, watery eyes, and runny nose), and dextromethorphan is a cough suppressant that relieves cough by acting on the cough center in the brain. Together, they relieve coughs effectively.

Q: What are the possible side effects of taking PHENSEDYL DX SYRUP?

A: The most common side effects of this medicine are sedation, somnolence, disturbance in attention, abnormal coordination, dizziness, drowsiness, headache, blurred vision, nausea, vomiting, dry mouth, abdominal discomfort, and fatigue. Contact your physician if any of the symptoms worsen.

Q: Does PHENSEDYL DX SYRUP cause sleepiness?

A: Yes. PHENSEDYL DX SYRUP causes sleepiness. Try to rest and relax. Get enough sleep. Avoid driving or operating any machines while you are feeling sleepy. Do not consume alcohol, as it can aggravate your sleepiness. Contact your doctor if your sleepiness does not improve.

Q: Is PHENSEDYL DX SYRUP safe during pregnancy and breastfeeding?

A: PHENSEDYL DX SYRUP is generally not recommended for use during pregnancy or in breastfeeding women as it may pass through the breast milk. Consult your doctor before taking it.

Q: Can I consume alcohol while taking PHENSEDYL DX SYRUP?

A: Avoid consumption of alcohol while taking PHENSEDYL DX SYRUP, as it may lead to unwanted effects.

Q: What precautions must be taken while using PHENSEDYL DX SYRUP?

A: Before taking PHENSEDYL DX SYRUP, inform your doctor if you have severe liver disease, kidney disease, heart disease, hypertension, epilepsy, glaucoma, urinary retention, prostatic enlargement, pyloroduodenal obstruction, thyrotoxicosis, or diabetes.

Q: Who should not take PHENSEDYL DX SYRUP?

A: PHENSEDYL DX SYRUP is not recommended for use if you have confusion, rare hereditary problems like fructose intolerance, glucose-galactose malabsorption, and sucrase-isomaltase insufficiency, or if you are at risk of developing respiratory failure (Ex. chronic obstructive airways disease, pneumonia, or an exacerbation of asthma), or are allergic to chlorpheniramine or dextromethorphan.

Q: Can I take other medicines while taking PHENSEDYL DX SYRUP?

A: Inform your healthcare provider about all medications, supplements, and herbal products you are taking, as they may interact with PHENSEDYL DX SYRUP. Certain medicines may interact with PHENSEDYL DX SYRUP and affect blood sugar levels.

Q: What should I do if I miss a dose of PHENSEDYL DX SYRUP?

A: If you miss a dose, take it as soon as you remember, unless it's almost time for your next dose. In that case, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one.

Q: Is it safe to buy PHENSEDYL DX SYRUP from online pharmacies like Netmeds?

A: Generally, it is safe to purchase PHENSEDYL DX SYRUP from reputable online pharmacies like Netmeds in India. Netmeds adheres to strict regulations to ensure the quality and authenticity of the medications. If you wish to buy PHENSEDYL DX SYRUP on Netmeds, you need a prescription from a registered medical practitioner. Netmeds has made buying online medicines easier for consumers and is one of India's leading online pharmacies.

References

1. K.D. Tripathi. Drugs for cough and bronchial asthma. Essentials of medical pharmacology. Seventh edition. 2013. Page – 220.

2. Bethesda (MD). Chlorpheniramine. National Institute of Health. NLM. National Centre for Biotechnology Information. PubChem Compound Summary. 2004. [Accessed on 12th March 2024] https://pubchem.ncbi.nlm.nih.gov/compound/Chlorpheniramine

3. Bethesda (MD). Dextromethorphan. National Institute of Health. NLM. National Centre for Biotechnology Information. PubChem Compound Summary. 2004. [Accessed on 12th March 2024] https://pubchem.ncbi.nlm.nih.gov/compound/5360696

4. GlaxoSmithKline Consumer Healthcare (UK). Electronic Medicines Compendium (EMC). [Revised in December 2020] [Accessed on 12th March 2024] https://www.medicines.org.uk/emc/files/pil.3928.pdf

5. Delpharm Orleans. Electronic Medicines Compendium (EMC). [Revised in February 2022] [Accessed on 12th March 2024] https://www.medicines.org.uk/emc/files/pil.1523.pdf

6. GlaxoSmithKline Pharmaceuticals Limited. Chlorpheniramine and Dextromethorphan. [Revised in November 2019] [Accessed on 12th March 2024] https://india-pharma.gsk.com/media/6399/piriton-cs.pdf

7. Accudial Pharmaceutical, Inc. Chlorpheniramine and Dextromethorphan. [Revised in November 2011] [Accessed on 12th March 2024] https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=03401433-923e-4577-ba58-9087515c8053

8. Cheston CS Syrup (Chlorpheniramine and Dextromethorphan). Cipla Ltd. [Revised in November 2013] [Accessed on 12th March 2024] https://www.ciplamed.com/product-index/cheston-cs-syrup