Percin Tablet 5'S
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Introduction About PERCIN TABLET
PERCIN TABLET contains Prulifloxacin which belongs to the group of medicines called Fluoroquinolones. PERCIN TABLET is used manage infections caused by susceptible bacteria which includes lower urinary tract infections with/without association with other urinary medical problems, sudden worsening of chronic bronchitis and/or acute bronchial rhinosinusitis (inflammation of nasal cavity and paranasal sinuses) in affected individuals.
PERCIN TABLET is also used to manage bacterial rhinosinusitis when usual antibiotics becomes infective/contraindicated to manage the disease.
PERCIN TABLET is not recommended for use in patients allergic (hypersensitive) to prulifloxacin, and/or other fluoroquinolones. It is also not recommended for use in patients suffering from tendonitis (inflamed tendons), and/or glucose-6-phosphate dehydrogenase deficiency (a genetic disorder that affects red blood cells).
Before taking PERCIN TABLET, inform your doctor if you have epilepsy/medical condition that may cause convulsions, lactose (type of sugar found in milk) intolerance, myasthenia gravis (muscle weakness), Glucose-6-phosphate dehydrogenase (G6PD) deficiency, heart problems (such as abnormal heart rhythm, QT interval prolongation, aortic aneurysm, tear in aorta wall), kidney, and/or liver problems.
PERCIN TABLET is not recommended for use in pregnant and breast-feeding women. It is also not recommended for use in children and adolescents (aged below 18 years) and is advised to be used with caution in elderly patients (aged 60 years/above) after consulting the doctor.
The most common side effect associated with the use of PERCIN TABLET is stomach pain. Consult your doctor if the symptom worsens.
Uses Of PERCIN TABLET
- Manage susceptible bacterial infections which include lower urinary tract infections (with/without association with other urinary medical problems), sudden worsening of chronic bronchitis, and/or acute bronchial rhinosinusitis in affected individuals
- Manage bacterial rhinosinusitis when usual antibiotics becomes infective/contraindicated to manage the disease
How PERCIN TABLET Works
PERCIN TABLET works by inhibiting DNA gyrase (enzyme responsible for DNA synthesis) in susceptible bacteria which results in destruction of bacterial cell structure thus managing the occurrence of bacterial infection in affected individuals.
How to use PERCIN TABLET
Take PERCIN TABLET as advised by your physician. Swallow the medicine with a glass of water. Do not crush or chew the medicine. Your doctor will decide the correct dose and duration for you depending upon your age, disease condition, and body weight.
Side Effects Of PERCIN TABLET
Common
- stomach pain
Uncommon
- inflammation of the stomach, loss of appetite, nausea, vomiting, diarrhoea
- headache, dizziness
- itching/rash
- loss of appetite
Rare
- fever, hot flushes
- changes in taste
- sleep disorders, confusion/sleepiness
- impaired hearing
- redness and irritation in the eyes
- indigestion, heartburn, wind, bloating, abnormal stools
- sore lips, tongue/mouth/fungal infection
- muscle spasms/breakdown
- dry skin, red wheals on the skin
- increased sensitivity to sunlight
- feeling restless
- mouth ulcer
- joint pains all over the body
Stop taking PERCIN TABLET and contact your doctor immediately if you experience any of the following side effects:
- sudden, severe pain in abdomen/chest/back
- severe/persistent watery diarrhoea (noticed with blood/mucus in stools)
- muscle pain/weakness, dark urine, tiny crystals in urine
- signs of neuropathy such as pain, burning, tingling, numbness, and/or weakness (especially in arms/legs)
- disabling/potentially irreversible conditions that includes tendon, muscle/joint pain of upper and lower limbs, difficulty in walking, abnormal sensations (such as burning/prickling sensation), sensory disorders (such as impairment of hearing, vision, taste/smell), depression, memory impairment, severe fatigue, and/or severe sleep disorders
- severe reaction to the sun such as burning/peeling sensation
- impaired eyesight
- sudden wheeziness, breathing difficulties, swelling of the eyelids, face/lips, rash/itching
- Stevens Johnson syndrome (rare/serious disorder of skin and mucous membrane) associated with signs such as severe skin rash, blistering of skin involving mouth and tongue
- signs of tendon inflammation such as swelling/pain in the affected limb
- signs of low blood sugar such as feeling shaky/irritable
- signs of dermatitis (inflammation of skin) such as skin reddening and flaking
How To Manage Side Effects
Nausea and vomiting:
Take PERCIN TABLET with/just after a meal. Stick to simple meals. Avoid eating oil rich/spicy foods, sugary snacks and drinks. Avoid drinking too much liquid along with your meals, and drink slowly in between meals. Consult your doctor if the condition worsens.
Diarrhoea:
Drink plenty of water and stay hydrated. Try to avoid taking any medicine on your own to manage diarrhea. Consult and inform your doctor if the symptom worsens.
Headache:
If PERCIN TABLET causes headache, then take rest and drink plenty of fluids. Try to avoid drinking alcohol. Ask your doctor to recommend a painkiller. Headaches should usually go away after the first week of taking PERCIN TABLET. If it lasts more than a week/becomes severe, then consult and inform your doctor.
Dizziness:
Try to rest and get enough sleep. Try to avoid driving or operating any tools or machines while you feel dizzy. Limit consumption of alcohol, as it can aggravate dizziness. Consult and inform your doctor if the symptom worsens.
Itchy Skin:
Try to pat or tap your skin instead of scratching it. Hold a damp towel to cool your skin. Wear loose clothing and avoid tight clothes, or clothes made from wool or synthetic fabrics. Avoid using perfumed soaps, deodorants or moisturizers and use a skin softener regularly.
Rashes:
Do not scratch the affected area. Wear protective clothing while going outdoors. Regularly moisturize your skin. Consult and inform your doctor if the symptom gets worse.
Indigestion:
Try to have smaller and more frequent meals and drink slowly. Reduce consumption of coffee, cola, tea, or alcohol and lose weight if you are obese. Try to avoid smoking and don’t have rich, fatty or spicy foods. Consult your doctor and inform if the symptom does not improve.
Warning & Precautions
Pregnancy
PERCIN TABLET is not recommended for use in pregnant women. Consult your doctor before taking the medicine.
Breastfeeding
PERCIN TABLET is not recommended for use in breastfeeding women. Consult your doctor before taking the medicine.
Driving and Using Machines
Do not drive or operate any machines if you feel dizzy or confused after taking PERCIN TABLET.
Kidney
PERCIN TABLET should be used with caution in patients with kidney problems. Consult your doctor before taking PERCIN TABLET.
Liver
PERCIN TABLET should be used with caution in patients with liver problems. Consult your doctor before taking PERCIN TABLET.
Allergy
Do not take PERCIN TABLET if you are allergic (hypersensitive) to prulifloxacin, other fluoroquinolones, and/or any other ingredients of this medicines.
Heart Disease
PERCIN TABLET should be used with caution in patients with heart problems such as abnormal heart rhythm, QT interval prolongation, aortic aneurysm, tear in aorta wall. Consult your doctor before taking PERCIN TABLET.
Others
PERCIN TABLET is not recommended for use if you:
- suffer from tendonitis (inflamed tendons)
- have glucose-6-phosphate dehydrogenase deficiency (genetic disorder of red blood cells)
Before taking PERCIN TABLET, inform your doctor if you:
- have epilepsy/medical condition that may cause convulsions (fits)
- have lactose (sugar found in milk) intolerance
- have myasthenia gravis (muscle weakness)
- have Glucose-6-phosphate dehydrogenase (G6PD) deficiency
- have a family history of connective tissue disorders (such as Marfan syndrome, vascular Ehlers-Danlos syndrome), vascular disorders (such as Takayasu arteritis, giant cell arteritis, Behcet's disease, high blood pressure, atherosclerosis)
Use in Paediatrics:
PERCIN TABLET is not recommended for use in children (aged below 18 years). Consult your doctor before taking PERCIN TABLET.
Use in Geriatrics:
PERCIN TABLET should be used with caution in elderly patients (aged 60 years/above). Consult your doctor before taking PERCIN TABLET.
Interactions
A. Drug–Drug Interactions:
Before taking PERCIN TABLET, inform your doctor if you are taking any of the following medicine:
- medicines used in the management of indigestion, heartburn or stomach ulcers (Ex. cimetidine)
- medicines containing calcium/iron
- medicines used in the management of diabetes (Ex. sitagliptin, metformin)
- medicines to control your heartbeat (Ex. amiodarone, quinidine, procainamide)
- other antibiotics (medicines used to manage bacterial infections) Ex. erythromycin, clarithromycin, azithromycin
- medicines used in the management of depression (Ex. amitriptyline, clomipramine, imipramine)
- medicines used to reduce uric acid in the blood (Ex. probenecid)
- medicines used for pain relief in arthritis (Ex fenbufen)
- medicines used for asthma or breathing difficulties (Ex. theophylline)
- medicines used to manage blood clotting (Ex. warfarin)
- medicines used to manage angina (chest pains) or high blood pressure (Ex. nicardipine)
- steroids for allergic conditions or inflammation (Ex. prednisolone)
B.Drug–Food Interactions:
PERCIN TABLET should not be taken with milk/milk products.
Overdosage:
If you or anyone else accidentally take too much of PERCIN TABLET, consult your doctor immediately or visit the nearby hospital to manage overdose symptoms.
Synopsis
| Drug | : | Prulifloxacin |
| Pharmacological Category | : | Fluoroquinolones |
| Therapeutic Indication | : | Susceptible bacterial infections (such as lower urinary tract infections with/without association with other urinary medical problems, sudden worsening of chronic bronchitis/acute bronchial rhinosinusitis, Bacterial rhinosinusitis |
| Dosage Forms | : | Tablet |
More Information
- Keep PERCIN TABLET out of reach of children
- Do not store PERCIN TABLET above 30°C
FAQs About PERCIN TABLET
What is PERCIN TABLET used for?
PERCIN TABLET is used manage infections caused by susceptible bacteria which includes lower urinary tract infections with/without association with other urinary medical problems, sudden worsening of chronic bronchitis and/or acute bronchial rhinosinusitis (inflammation of nasal cavity and paranasal sinuses). It is also used to manage bacterial rhinosinusitis when usual antibiotics becomes infective/contraindicated to manage the disease in affected individuals.
What are the common side effects of taking PERCIN TABLET?
The most common side effect associated with the use of PERCIN TABLET is stomach pain. Consult your doctor if the symptom worsens.
How PERCIN TABLET works?
PERCIN TABLET works by inhibiting DNA gyrase (enzyme responsible for DNA synthesis) in susceptible bacteria which results in destruction of bacterial cell structure thus managing the occurrence of bacterial infection in affected individuals.
How PERCIN TABLET should be taken?
Take PERCIN TABLET as advised by your physician. Swallow the medicine with a glass of water. Do not crush or chew the medicine. Your doctor will decide the correct dose and duration for you depending upon your age, disease condition, and body weight.
Can PERCIN TABLET be used in pregnant and breastfeeding women?
No, PERCIN TABLET is not recommended for use in pregnant and breastfeeding women. Consult your doctor before taking the medicine.
References
1. K.D. Tripathi. Sulfonamides, Cotrimoxazole and Quinolones. Essentials of medical pharmacology. Seventh edition. 2013. Page – 714.
2. Guillem Prats, Vilma Rossi, Enrica Salvatori, Beatriz Mirelis. Prulifloxacin: a new antibacterial fluoroquinolone. NIH National Library of Medicine. National Center for Biotechnology Information. PubMed.gov. February 2006. [Accessed on 1st June 2022] https://pubmed.ncbi.nlm.nih.gov/16441207/
3. NIH National Library of Medicine, National center for biotechnology information. Pubchem. Prulifloxacin. [Accessed on 1st June 2022] https://pubchem.ncbi.nlm.nih.gov/compound/Prulifloxacin
4. A.C.R.A.F. S.p.A. Glimbax 600mg. [Revised in April 2020] [Accessed on 1st June 2022] https://meditrina.gr/wp-content/uploads/2020/12/Glimbax_PIL_2020_04_ENG.pdf
Useful Diagnostic Tests
- Chest X-ray
- Bacterial culture test
Author Details
The contents of this website are for informational purposes only and not intended to be a substitute for professional medical advice, diagnosis, or treatment. Please seek the advice of a physician or other qualified health provider with any questions you may have regarding a medical condition. Do not disregard professional medical advice or delay in seeking it because of something you have read on this website.
