PANSEC IV (WITH DILUENT) INJECTION is used to manage peptic ulcers, gastroesophageal reflux disease (GERD) or reflux esophagitis and its associated symptoms such as acidity, heartburn, acid reflux and pain in swallowing. It contains Pantoprazole which belongs to the group of medicines called Proton pump inhibitors.  

Uses Of PANSEC IV (WITH DILUENT) INJECTION

It is used to manage:

• Peptic ulcer
• Gastrointestinal Reflux disease (GERD)
• Reflux esophagitis (inflammation of the esophagus)
• Acidity, Heartburn, Pain in swallowing
• Zollinger-Ellison syndrome (tumors in pancreas causing the stomach to secrete more acid)

How PANSEC IV (WITH DILUENT) INJECTION Works

PANSEC IV (WITH DILUENT) INJECTION reduces gastric acid secretion by the blocking the actions of a protein membrane called H+K+Atpase (proton pump) across the stomach lining. As a result, it manages the worsening of ulcers, heals the existing ulcers and esophageal lesions and provides relief from the unpleasant symptoms of GI tract (such as acidity, heartburn and acid reflux).

How to use PANSEC IV (WITH DILUENT) INJECTION

• It will be administered to you only by a doctor or a nurse into the vein (intravenously)
• Your doctor will decide the correct dose and duration of therapy for you depending upon your age, body weight and disease condition

Side Effects Of PANSEC IV (WITH DILUENT) INJECTION

Common side effects of PANSEC IV (WITH DILUENT) INJECTION:

• benign polyps in the stomach
• injection site reactions (pain and inflammation)
• nausea or vomiting
• diarrhea, constipation, stomach pain, flatulence
• dry mouth

Contact your doctor immediately if you experience any of the following side effects after receiving PANSEC IV (WITH DILUENT) INJECTION:

• severe allergic reactions (skin rash, itching, swelling of the lips, face or body and difficulty in breathing or swallowing)
• signs of liver problems (yellowing of the skin and eyes, dark urine and tiredness)
• severe skin reactions (redness, blistering, peeling of skin and bleeding in the lips, eyes, mouth, nose and genitals with fever)
• signs of kidney problem (lower back pain, painful urination)
• signs of low magnesium levels in blood (tiredness, abnormal muscle movements, dizziness, confusion, disorientation, irregular heartbeat)
• uncontrollable body movements (including eye and tongue), twisted neck and abnormal body posture

Warning & Precautions

Pregnancy

Monitoring required

PANSEC IV (WITH DILUENT) INJECTION should be used in pregnant women only if it is considered necessary by the physician.

Breastfeeding

Monitoring required

PANSEC IV (WITH DILUENT) INJECTION may pass through breast milk. Therefore, it should be used in breastfeeding women only if it is considered necessary by the physician.

Driving and Using Machines

Use with Caution

PANSEC IV (WITH DILUENT) INJECTION does not affect your ability in driving or handling heavy tools or machines.

Alcohol

Consult your doctor

Avoid consumption of alcohol while receiving PANSEC IV (WITH DILUENT) INJECTION, as it could aggravate your existing condition.

Kidney

Use with Caution

PANSEC IV (WITH DILUENT) INJECTION should be used with caution in patients with kidney problems.

Liver

Use with Caution

PANSEC IV (WITH DILUENT) INJECTION should be used with caution in patients with liver problems.

Allergy

Contraindicated

Do not receive PANSEC IV (WITH DILUENT) INJECTION if you are allergic to Pantoprazole or any other ingredients of this medicine.

Use In Pediatrics

Contraindicated

PANSEC IV (WITH DILUENT) INJECTION is not recommended for use in children and adolescents (aged below 18 years).  

Use In Geriatrics

Use with Caution

PANSEC IV (WITH DILUENT) INJECTION should be used with caution in elderly patients (aged 65 years and above).

Interactions

A. Drug-Drug interactions:

Before receiving PANSEC IV (WITH DILUENT) INJECTION inform your doctor if you are receiving any of the following medicines such as:

• Antifungal (Ex. ketoconazole, itraconazole and Posaconazole)
• Anti-cancer agents (Ex. Erlotinib)
• Anticoagulants (Ex. Warfarin and phenprocoumon)
• Antimetabolites (Ex. methotrexate)
• Anti-viral agents (Ex. atazanavir)
• Antidepressants (Ex. fluvoxamine)
• Antibiotics (Ex. rifampicin)
• Herbal medicine (Ex. St. John’s wort)

Overdosage:

PANSEC IV (WITH DILUENT) INJECTION will be administered only by a doctor or a nurse in a hospital, and so it is unlikely to receive an overdose. However, consult your doctor or nurse if you experience any unusual symptoms.

Synopsis

More Information

FAQs About PANSEC IV (WITH DILUENT) INJECTION

References

1. KD Tripathi. Drugs for Peptic Ulcer and Gastroesophageal Reflux Disease. Essentials of medical pharmacology. Eighth Edition. 2019. Page –701.

2. H Wurzer, K Schutze, T Bethke, R Fischer, R Luhmann, C Riesenhuber. Efficacy and safety of pantoprazole in patients with gastroesophageal reflux disease using an intravenous-oral regimen. Austrian Intravenous Pantoprazole Study Group. NIH. National Library of Medicine. National Center for Biotechnology Information. Pubmed.gov. May-June 1999. [Accessed on 22nd October 2022] click here

3. Sun Pharmaceutical Industries Europe B.V. Electronic Medicines Compendium (EMC). [Revised in August 2021] [Accessed on 22nd October 2022] click here

4. Central Drugs Standard Control Organization. Pantoprazole. Each vial contains pantoprazole sod. Eq to Pantoprazole 40mg. S(-) Pantoprazole (as sodium) Inj 20mg/vial. [Revised in June 2006] [Accessed on 22nd October 2022] click here

Useful Diagnostic Tests

• Complete Blood Count (CBC)
• Stool Complete Analysis

Author Details

Written By Srilekha. R - B.Pharm

Reviewed By Dr. Sankara Babu Gorle - MBBS, MD(Pharmacology) View profile

Last updated on 21 Nov 2024 | 10:09 AM(IST)