OTRIZEST 0.1% Nasal Spray 10ml
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Introduction About OTRIZEST 0.1% NASAL SPRAY
OTRIZEST 0.1% NASAL SPRAY is paediatric nasal drop used for symptomatic relief from nasal congestion in children. OTRIZEST 0.1% NASAL SPRAY reduces nasal congestion, excessive nasal secretion and restores normal breathing. It contains a medicine called xylometazoline which works by thinning the mucus present in the nasal tract.
Always use OTRIZEST 0.1% NASAL SPRAY as directed by your physician.One to two drops in each nostril, one or two times daily or as directed by the physician. It is for intranasal use only. Do not use OTRIZEST 0.1% NASAL SPRAY for more than 7 days without consulting your doctor.
Before using OTRIZEST 0.1% NASAL SPRAY inform your doctor if you have diabetes, hypertension, glaucoma, hyperthyroidism, or any heart problems. You must also inform your doctor if you have any other problems in nasal tract apart from nasal congestion such as chronic nasal inflammation with very dry nasal passages (rhinitis sicca or atrophic rhinitis).
The most common side effects of using OTRIZEST 0.1% NASAL SPRAY are irritation or burning sensation after application and nasal dryness. Consult your doctor if any of these side effect worsens.
Uses Of OTRIZEST 0.1% NASAL SPRAY
- Nasal congestion
How OTRIZEST 0.1% NASAL SPRAY Works
OTRIZEST 0.1% NASAL SPRAY opens and clears the nasal passages. It works by narrowing down the blood vessels supplying the nasal passage. This helps swollen blood vessels of the nasal tract to return to its normal size which allows the air to pass through the nostrils more freely. It also reduces excessive nasal secretions and provides temporary relief from nasal inflammation, swelling and discomfort.
How to use OTRIZEST 0.1% NASAL SPRAY
Always use OTRIZEST 0.1% NASAL SPRAY as directed by your physician. It is for intranasal use only.
For Nasal Drops: Gently instill few drops of this medicine into each nostril. One to two drops in each nostril, one or two times daily or as directed by the physician.Clean the dropper after application.
For Nasal Spray: Insert the spray nozzle inside the affected nostril. Press the pump to release the spray and sniff at the same time. Repeat the same to the other nostril if required. Clean the nozzle after application.
To avoid possible spread of infection, this pack should only be used by a single person. Do not use OTRIZEST 0.1% NASAL SPRAY for more than 7 days without consulting your doctor. Discard the unused portion after 28 days of opening it.
Side Effects Of OTRIZEST 0.1% NASAL SPRAY
Common
- Dry nose
- Nose discomfort
- Headache
- Nausea
- Irritation or burning sensation after application
Uncommon
- Nosebleeds
Rare
Stop using OTRIZEST 0.1% NASAL SPRAY and contact your doctor immediately if you experience any of the following side effects:
- Severe allergic reactions (such as swelling of the face, lips, tongue, and/or throat which can lead to difficulty in breathing or swallowing)
- Severe itching of the skin, with a red rash or raised spots on the skin.
How To Manage Side Effects
Headache
Rest and relax. Keep yourself hydrated by drinking plenty of fluids such as water or electrolytes. Applying a pain-relieving balm on your forehead can be beneficial. Do not consume excessive alcohol, as it could aggravate your headache. Consult your doctor if your headache worsens.
Nausea And Vomiting
Take OTRIZEST 0.1% NASAL SPRAY with or just after meals. Stick to simple meals. Avoid eating oil rich or spicy foods. Consult your doctor if your nausea worsens.
Warning & Precautions
Driving and Using Machines
Use with CautionDo not drive or operate any tools or machines if your ability is affected by OTRIZEST 0.1% NASAL SPRAY.
Allergy
ContraindicatedDo not use OTRIZEST 0.1% NASAL SPRAY if you are allergic to Xylometazoline or to any other ingredients of this medicine.
Heart Disease
Use with CautionOTRIZEST 0.1% NASAL SPRAY should be used with caution in patients with heart disease (such as hypertension, prolonged QT syndrome). Therefore, consult your doctor before using it.
Use In Pediatrics
Consult your doctorOTRIZEST 0.1% NASAL SPRAY can be used in children and adolescents aged 12 years or above. You must consult your doctor before using OTRIZEST 0.1% NASAL SPRAY if your child is aged 6 years or above. It is not recommended for use in children aged below 6 years. Therefore, consult your doctor for advice before administration
Use In Geriatrics
Use with CautionOTRIZEST 0.1% NASAL SPRAY should be used with caution in elderly patients. Therefore, consult your doctor for advice.
Others
OTRIZEST 0.1% NASAL SPRAY is not recommended for use if you:
- Have had a recent neurosurgery
- Have narrow-angle glaucoma (increased pressure within the eyes)
- Have any problems in the nasal tract such as chronic nasal inflammation with very dry nasal passages (rhinitis sicca or atrophic rhinitis)
- Have an enlarged prostate gland
- Have phaeochromocytoma (a rare tumour of the adrenal glands)
Before using OTRIZEST 0.1% NASAL SPRAY, inform your doctor if you:
- Have diabetes
- Have hyperthyroidism (overactive thyroid gland)
Interactions
A. Drug-Drug interactions:
- Antidepressants such as monoamine oxidase inhibitors (Ex. moclobemide, isocarboxazid, phenelzine and tranylcypromine), tricyclic antidepressants (Ex. amitriptyline, nortriptyline), lithium, fluoxetine, sertraline, citalopram, escitalopram etc
- alpha-blockers (Ex. prazosin, terazocin) or beta blockers (Ex. propranolol, atenolol)
- antiglaucoma (Ex. Timolol, betaxolol)
Overdosage:
If you or anyone else accidentally applied too much of OTRIZEST 0.1% NASAL SPRAY, consult your doctor immediately.
Synopsis
| Drug | : | Xylometazoline |
| Pharmacological Category | : | Alpha-Adrenergic Agonist |
| Therapeutic Indication | : | Nasal congestion, sinusitis, perennial allergic rhinitis |
| Dosage Forms | : | Nasal Drops, Nasal Spray |
More Information
Storage
- Keep OTRIZEST 0.1% NASAL SPRAY out of reach to children
- Store OTRIZEST 0.1% NASAL SPRAY at room temperature
FAQs About OTRIZEST 0.1% NASAL SPRAY
Q: What is the use of OTRIZEST 0.1% NASAL SPRAY ?
A: OTRIZEST 0.1% NASAL SPRAY is used to relieve nasal congestion caused due to common cold, sinusitis or allergic rhinitis.
Q: Can OTRIZEST 0.1% NASAL SPRAY be used every day?
A: Use OTRIZEST 0.1% NASAL SPRAY for the duration prescribed by your doctor. Do not use OTRIZEST 0.1% NASAL SPRAY for more than 7 days without consulting your doctor. Prolonged use of OTRIZEST 0.1% NASAL SPRAY may worsen your condition.
Q: Is it safe to use OTRIZEST 0.1% NASAL SPRAY ?
A: Yes. OTRIZEST 0.1% NASAL SPRAY is one of the safe and well-tolerated medicine. It does not cause any harmful side effects. It may cause local irritation or burning sensation after application which is quite normal and disappears after a few minutes.
Q: What are the common side effects of OTRIZEST 0.1% NASAL SPRAY ?
A: The most common side effects of using OTRIZEST 0.1% NASAL SPRAY are irritation or burning sensation after application and nasal dryness. Consult your doctor if they bother you.
Q: Can OTRIZEST 0.1% NASAL SPRAY be used in children?
A: OTRIZEST 0.1% NASAL SPRAY can be used in children and adolescents aged 12 years or above. You must consult your doctor before using OTRIZEST 0.1% NASAL SPRAY if your child is aged 6 years or above. It is not recommended for use in children aged below 6 years. Therefore, consult your doctor for advice before administration.
Q: Is OTRIZEST 0.1% NASAL SPRAY an antihistamine?
A: OTRIZEST 0.1% NASAL SPRAY is a sympathomimetic agonist which directly acts on the alpha-adrenergic receptors of the blood vessels supplying the nasal tract and narrows them down. This reduces swelling of the nasal tract and allows the air to pass through the nostrils more freely.
Q: How long it takes for OTRIZEST 0.1% NASAL SPRAY to work?
A: OTRIZEST 0.1% NASAL SPRAY may show its therapeutic effect after 5 to 10 minutes of application. It works by narrowing of blood vessels in the affected lining of the nose and helps to provide relief from congestion.
Q: Can OTRIZEST 0.1% NASAL SPRAY cause rebound congestion?
A: Yes, OTRIZEST 0.1% NASAL SPRAY may cause rebound congestion (worsening of congestion due to nasal decongestant sprays) if you use for more than the duration recommended by your doctor.
References
1. K.D. Tripathi. Adrenergic System and Drugs. Essential of Medical Pharmacology. 7th Edition. Page – 136.
2. Xylometazoline. ScienceDirect.com. [Accessed on 8thJuly 2024]. https://www.sciencedirect.com/topics/medicine-and-dentistry/xylometazoline#:~:text=Clinical%20Pharmacology%3A,Therapeutic%20Effect%3A%20Decreased%20nasal%20congestion.
3. Ronald Eccles, Kaj Martensson and Shirley C. Chen. Effects of intranasal xylometazoline, alone or in combination with ipratropium, in patients with common cold. Taylor Francis Online. January 2010. [Accessed on 8thJuly 2024]. https://www.tandfonline.com/doi/abs/10.1185/03007991003648015?journalCode=icmo20
4. GlaxoSmithKline Consumer Healthcare (UK). Electronic Medicines Compendium (EMC). [Revised in August 2021] [Accessed on 8thJuly 2024]. https://www.medicines.org.uk/emc/files/pil.5984.pdf
5. GlaxoSmithKline Consumer Healthcare (UK). Electronic Medicines Compendium (EMC). [Revised in August 2021] [Accessed on 8thJuly 2024]. https://www.medicines.org.uk/emc/files/pil.1412.pdf
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