Introduction About ORNOF RF SYRUP

ORNOF RF SYRUP contains Ofloxacin, which belongs to the group of medicines called Antibiotics. It is used in children to manage bacterial infections of the eyes, ears, nose, throat, lungs, skin and urinary tract. Bacterial infections are generally characterized by fever, extreme tiredness, swollen lymph nodes in the neck, armpits, groin or elsewhere, headache, nausea or vomiting.

Ofloxacin works by binding to and inhibiting bacterial enzymes required in DNA synthesis, thus interrupting DNA replication and managing bacterial cell multiplication.

Before using ORNOF RF SYRUP, inform your doctor if you have any other conditions or if you are using or taking other medicines. It should be used cautiously in pregnant and breastfeeding women. Your doctor will prescribe the right dose of ORNOF RF SYRUP for your child depending on age, body weight and severity of infection.

The most common side effects of taking ORNOF RF SYRUP are vomiting, nausea, stomach pain, diarrhoea, loss of appetite, headache, difficulty sleeping and dizziness. Contact your doctor if any of the symptoms worsen.

Uses Of ORNOF RF SYRUP

It is indicated for the management of the following bacterial infections in children:

• eye infection
• ear infection
• nose infection
• throat infection
• lung infection
• skin infection
• urinary tract infection

How ORNOF RF SYRUP Works

ORNOF RF SYRUP works by binding to and inhibiting bacterial enzymes required in DNA synthesis, thus interrupting DNA replication and managing bacterial cell multiplication.

How to use ORNOF RF SYRUP

Take ORNOF RF SYRUP as advised by your physician. Shake well before use. Your doctor will decide the correct dose and duration for you according to your age, body weight and severity of infection.

Side Effects Of ORNOF RF SYRUP

How To Manage Side Effects

Nausea:

Take regular sips of a cold drink. Have ginger or peppermint tea. Stick to simple meals. Avoid eating oily or spicy foods. If nausea does not improve, contact your doctor.

Vomiting:

Get adequate rest. Drink lots of fluids, especially water. Have small sips if you feel sick. Eat when you feel like it – you do not need to eat or avoid any specific foods. If vomiting does not improve, contact your doctor.

Headache:

Drink an ample amount of water. Get adequate rest. Try to be relaxed and stress-free. Ask your doctor before taking any medicine for headaches. Consult your doctor immediately if your symptom does not improve.

Dizziness:

Lie down until the dizziness is gone, then get up slowly. Move slowly and carefully, do not hurry. Get adequate rest. Drink plenty of water and other fluids. Avoid coffee, cigarettes, alcohol and drugs. Consult your doctor immediately if your symptom does not improve.

Diarrhoea:

Drink lots of fluids, like water or fruit juice to keep yourself hydrated. Do not consume any medicine on your own without consulting your doctor. Consult your doctor immediately if your symptom does not improve.

Stomach pain:

Try to rest and relax. Eat and drink slowly or try to eat smaller meals more frequently. Keep a heating pad on your stomach. Consult your doctor immediately if your symptom does not improve.

Decreased appetite:

Eat when you are hungry. Eat smaller meals more often than usual. Snack only when you are hungry. Eat a nutritious snack rich in calories and protein, such as dried fruit and nuts. Consult your doctor immediately if your symptom does not improve.

Warning & Precautions

Pregnancy

ORNOF RF SYRUP should be used with caution in pregnant women. Consult your doctor before taking it.

Breastfeeding

ORNOF RF SYRUP should be used with caution in breastfeeding women. Consult your doctor before taking it.

Driving and Using Machines

Consult your doctor if you feel any side effects during management with ORNOF RF SYRUP that may stop you from driving or using machines.

Allergy

Do not take ORNOF RF SYRUP if you are allergic to Ofloxacin or any of the other ingredients of this medicine or previously had an allergic reaction to any quinolone antibiotic.

Interactions

A. Drug-Drug interactions:

Before using ORNOF RF SYRUP, inform your doctor if you are taking, have taken or might take any other medicine, including prescription, non-prescription or any herbal medicine.

Overdosage:

If you or anyone else accidentally take too much of ORNOF RF SYRUP, contact your doctor immediately.

Synopsis

More Information

• Keep ORNOF RF SYRUP out of reach from children
• Store below 25°C

FAQs About ORNOF RF SYRUP

Does ORNOF RF SYRUP manage urinary tract infections?

Yes. ORNOF RF SYRUP is used to manage urinary tract infections. Your doctor will decide the correct dose and duration for you depending upon your age, body weight and severity of infection.

Can ORNOF RF SYRUP manage typhoid?

According to some studies, ORNOF RF SYRUP can be used to manage typhoid, in adults who are infected with S. typhi resistant to other medicines like chloramphenicol, ampicillin and cotrimoxazole. However, consult your doctor before giving ORNOF RF SYRUP to your child for indications other than those prescribed.

Can ORNOF RF SYRUP cause a headache?

Yes. ORNOF RF SYRUP may cause headaches. In such cases, drink ample amount of water and get adequate rest. Try to be relaxed and stress-free. Ask your doctor before taking any medicine for headaches. If the headache does not improve, contact your doctor.

What if I forget to take a dose of ORNOF RF SYRUP?

If you forget to take a dose of ORNOF RF SYRUP, take it as soon as you remember. However, omit the missed dose if it is almost time for the next dose. Do not take medicine twice to make up for a forgotten dose.

Can ORNOF RF SYRUP be stopped?

Continue taking ORNOF RF SYRUP until your doctor tells you to stop, unless you experience any unwanted effects, worsening of your condition or any new symptoms. In such a case, contact your doctor right away.

Can I take other medicines with ORNOF RF SYRUP?

Before taking ORNOF RF SYRUP, inform your doctor if you are taking, have taken or might take any other medicine, including prescription, non-prescription or any herbal medicine, as these might interact with each other and cause serious side effects.

Can ORNOF RF SYRUP cause nausea?

Yes. If you feel nauseous, take ORNOF RF SYRUP with or just after meals. Stick to simple meals. Avoid eating oily or spicy foods. If nausea does not improve, contact your doctor.

Can I drive a car after taking ORNOF RF SYRUP?

Do not drive if you experience dizziness after taking ORNOF RF SYRUP. Consult your doctor if you feel any side effects during management with ORNOF RF SYRUP that may stop you from driving or using machines.

References

1. K D Tripathi. Sulfonamides, Cotrimoxazole and Quinolones. Essentials of Medical Pharmacology. Seventh edition. 2013. Page – 713.

2. Derrick B. Graham; Jayson Tripp. Ofloxacin. StatPearls [Internet]. StatPearls Publishing. March 2022. [Accessed on 13th July 2022] https://www.ncbi.nlm.nih.gov/books/NBK549837/

3. Shin YJ, Choi JS, Chung JH, Han JY, Ahn HK, Ryu HM. Pregnancy outcomes in women reporting exposure to ofloxacin in early pregnancy. NIH National Library of Medicine, National center for biotechnology information. Pubmed.gov. August 2018. [Accessed on 13th July 2022] https://pubmed.ncbi.nlm.nih.gov/29565187/#:~:text=Ofloxacin%20and%20other%20quinolones%20are,of%20concerns%20about%20cartilage%20toxicity.

4. Drugs and Lactation Database (LactMed). Ofloxacin. NIH National Library of Medicine, National center for biotechnology information. [Revised in February 2021] [Accessed on 13th July 2022] https://www.ncbi.nlm.nih.gov/books/NBK501055/#:~:text=Use%20of%20ofloxacin%20is%20acceptable,infant%20to%20ofloxacin%20in%20breastmilk.

5. Fostini R, Girelli M, Dalle Vedove P, Benedetti M, Recchia G. Safety profile of ofloxacin in elderly patients. NIH National Library of Medicine, National center for biotechnology information. Pubmed.gov. 1988. [Accessed on 13th July 2022] https://pubmed.ncbi.nlm.nih.gov/3063474/

6. Ishaq M, Farooqui BJ, Ashfaq MK, Khan MA. Therapeutic implications of ofloxacin in the treatment of typhoid fever caused by multiply resistant Salmonella typhi. NIH National Library of Medicine, National center for biotechnology information. Pubmed.gov. August 1990. [Accessed on 13th July 2022] https://pubmed.ncbi.nlm.nih.gov/2126297/#:~:text=We%20concluded%20that%20ofloxacin%20can,to%20chloramphenicol%2C%20ampicillin%20and%20cotrimoxazole.

7. Elkos Healthcare. Ofloxacin. [Accessed on 13th July 2022] https://www.elkosgroup.in/product-details.php?name=OFLOKOS-100

8. Elkos Healthcare. Ofloxacin. [Accessed on 13th July 2022] https://www.elkosgroup.in/product-details.php?name=OFLOKOS-50

Useful Diagnostic Tests

• Bacterial culture
• Microscopic examination
• Completed Blood Count (CBC)