Introduction About OPTIFLEV EYE DROPS

OPTIFLEV EYE DROPS is a combination of Flurbiprofen and Hydroxypropyl methylcellulose (HPMC) which belongs to the group of medicines called NSAIDs and Eye lubricants. It is used to manage narrowing of pupil (black hole on the centre of the eye) during eye surgery (cataract removal) and post-surgical inflammation of eyes.

OPTIFLEV EYE DROPS is also used to manage Pseudophakic Cystoid macular edema (swelling of part of eye called macula with fluid due to complication of cataract surgery), eye pain associated with surgery and Post operative dry eye.

OPTIFLEV EYE DROPS is not recommended for use if you have viral eye infection or have a tendency to bleed. Contact your doctor before using it.

OPTIFLEV EYE DROPS is not recommended for use in third trimester of pregnancy and inform your doctor if you are breastfeeding before using this medicine.

The most common side effects of using OPTIFLEV EYE DROPS are burning or stinging sensations, eye irritation or discomfort. Contact your physician if any of the symptoms worsen.

Uses Of OPTIFLEV EYE DROPS

Manage:

• Prevent narrowing of pupil during eye surgery (cataract removal)
• Post-surgical inflammation of eyes
• Pseudophakic cystoid macular edema
• Eye pain associated with surgery
• Post operative dry eye

How OPTIFLEV EYE DROPS Works

Flurbiprofen present in the OPTIFLEV EYE DROPS works by stopping the pupil (inner part of the eye) from narrowing. Thus, it makes it easy for a doctor to check the eye during surgery or changing the lens and also blocks the release of certain chemicals called prostaglandins that cause pain, inflammation and irritation in the eye. While Hydroxypropyl methylcellulose is an Eye lubricant used to reduce dryness and soreness irritation. It also helps to manage damage to the eye in certain eye diseases.

How to use OPTIFLEV EYE DROPS

Instil OPTIFLEV EYE DROPS into the eye as advised by your physician. Shake well before use. It is for ophthalmic use only. OPTIFLEV EYE DROPS is normally instilled by your doctor. The doctor will instil the drops in your eye.

But if you are putting the eye drops in yourself, then wash your hands, tilt your head back and look at the ceiling. Gently pull the lower eyelid down until there is a small pocket. Turn the bottle upside down and squeeze it to release drop into the affected eye and close your eye for 30 seconds. Do not touch tip of container to any surface to avoid contamination.

Side Effects Of OPTIFLEV EYE DROPS

Warning & Precautions

Pregnancy

Contraindicated

OPTIFLEV EYE DROPS is not recommended for use in third trimester of pregnancy. Contact your doctor for advice before using it.

Breastfeeding

Consult your doctor

Before using OPTIFLEV EYE DROPS inform your physician if you are breastfeeding women.

Driving and Using Machines

Use with Caution

Do not drive or operate any machines if you have blurred vision after using OPTIFLEV EYE DROPS.

Allergy

Contraindicated

Do not use OPTIFLEV EYE DROPS if you are allergic to Flurbiprofen and Hydroxypropyl methylcellulose (HPMC) or other similar medicines, aspirin or to other ingredients of this medicine.

Interactions

A. Drug-Drug interactions:

Tell your doctor if you are applying or have recently taken any other medicines, including medicines obtained without a prescription, vitamin supplement or herbal products.

• medicine that affects the blood clots

Overdosage:

If you or anyone else accidentally take too much of OPTIFLEV EYE DROPS, consult your doctor immediately or visit the nearby hospital. If you have placed too many drops in your eye(s), wash your eye(s) with clean water. Apply your next dose at the normal time.

Synopsis

More Information

• Keep OPTIFLEV EYE DROPS out of the sight and reach of children
• Store OPTIFLEV EYE DROPS below 30°C

FAQs About OPTIFLEV EYE DROPS

Q: What precautions have to be taken while using OPTIFLEV EYE DROPS?

A: OPTIFLEV EYE DROPS is used 2 hours before the surgery. It should be used only after consulting with the doctor, as it contains the inactive ingredients which can cause allergic reactions or other problems. Consult your physician if you have any history of eye surgery.

Q: Can I use another eye drops along with OPTIFLEV EYE DROPS?

A: Other eye medicine should not usually be used with OPTIFLEV EYE DROPS. However, if your doctor recommends using OPTIFLEV EYE DROPS with another eye medicine, leave at least 5 minutes between putting in OPTIFLEV EYE DROPS and the other medicine.

Q: What if I forget to use OPTIFLEV EYE DROPS?

A: If you forget to use OPTIFLEV EYE DROPS, you should take the missed dose as soon as you remember, unless it is nearly time for the next dose. Do not take a double dose to make up for a missed dose and if a drop misses your eye, try again.

Q: Can I wear contact lens while using OPTIFLEV EYE DROPS?

A: OPTIFLEV EYE DROPS contains benzalkonium chloride may be absorbed by soft contact lenses and may change the colour of the contact lenses. You should remove contact lenses before using this medicine and put them back 15 minutes afterwards.  Benzalkonium chloride may also cause eye irritation, especially if you have dry eyes or disorders of the cornea (the clear layer at the front of the eye). If you feel abnormal eye sensation, stinging or pain in the eye after using this medicine, contact your doctor.

References

1. K.D. Tripathi. NSAIDs and Antipyretic-Analgesics. Essentials of medical pharmacology. Seventh edition. 2013. Page – 201.

2. Ahuja M, Dhake AS, Sharma SK, Majumdar DK. Topical ocular delivery of NSAIDs. NIH National Library of Medicine, National Center for Biotechnology Information. PubMed Central. June 2008. [Accessed on 21st July 2022]. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2751374/

3. Sarkar S, Mondal KK, Roy SS, Gayen S, Ghosh A, De RR. Comparison of preoperative nepafenac (0.1%) and flurbiprofen (0.03%) eye drops in maintaining mydriasis during small incision cataract surgery in patients with senile cataract: A randomized, double-blind study. NIH National Library of Medicine, National Center for Biotechnology Information. PubMed Central. Sep-Oct 2015. [Accessed on 21st July 2022]. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4621668/

4. FDC International Ltd. Electronic Medicines Compendium (EMC). [Revised in June 2020] [Accessed on 21st July 2022]. https://www.medicines.org.uk/emc/files/pil.457.pdf

5. Allergan Pharmaceuticals Ireland. Electronic Medicines Compendium (EMC). [Revised in February 2022] [Accessed on 21st July 2022]. https://www.medicines.org.uk/emc/files/pil.1343.pdf

6. Flurbi- SP eye drops (Flurbiprofen and Hydroxypropyl methylcellulose). Spectra Vision Care. [Accessed on 21st July 2022]. https://www.spectravisioncare.in/product/flurbiprofen-0-03-hpmc25

7. FLURVIS Eye drops (Flurbiprofen and Hydroxypropyl methylcellulose). Salvador Visontech. [Accessed on 21st July 2022]. http://www.salvadorvisiontech.com/products

8. TAKFLUR EYE DROPS (Flurbiprofen and Hydroxypropyl methylcellulose). Pharmtak Ophthalmics Pvt Ltd. [Accessed on 21st July 2022]. https://www.pharmtakindia.com/product/takflur-eye-drops/

9. OPTIFLEV EYE DROPS (Flurbiprofen and Hydroxypropyl methylcellulose). Leeford Healthcare Ltd. [Accessed on 21st July 2022]. https://www.leeford.in/product/135/optiflev-eye-drops