Introduction About ONDAMAC MD TABLET

ONDAMAC MD TABLET is used to provide relief from sensation of nausea and vomiting. It contains a medicine called Ondansetron which is an anti-emetic medicine. It reduces the nausea and vomiting sensation by blocking the vomiting centres of the brain.

Before taking ONDAMAC MD TABLET, inform your doctor if you have severe constipation, heart or liver problems, imbalance with the levels of salts in the blood, such as potassium, sodium and magnesium or if you have been scheduled for any surgery.

Consult your doctor before taking ONDAMAC MD TABLET if you are pregnant or breastfeeding.

The dose of ONDAMAC MD TABLET will depends on the age, body weight and disease condition of your child. Dosage adjustment is not required in elderly patients, hence consult your doctor before taking ONDAMAC MD TABLET.

The most common side effects of taking ONDAMAC MD TABLET includes headache, flushing and constipation. Consult your doctor if any of these above symptoms gets worse.

Uses Of ONDAMAC MD TABLET

• Management of nausea and vomiting

How ONDAMAC MD TABLET Works

ONDAMAC MD TABLET is anti-emetic medicine which works by blocking the action of serotonin, a natural substance in the body that can trigger nausea and vomiting. Specifically, it targets the 5-HT3 receptors in the brain and the gastrointestinal tract. By inhibiting these receptors, ondansetron effectively reduces the signals that lead to nausea and vomiting, providing relief to patients undergoing treatments that can induce these symptoms.

How to use ONDAMAC MD TABLET

Take ONDAMAC MD TABLET as advised by your physician. It can be taken with or without food.

For Tablet, Capsule: Swallow ONDAMAC MD TABLET with a glass of water. Do not crush or chew the medicine.

For Dispersible Tablet: Disperse the medicine in the specified quantity of water as mentioned in the label. Consume the medicine immediately after reconstitution.

For Oral Disintegrating strips: Place the medicine directly on your tongue and allow it to dissolve. For fast-dissolving strips, place the strip on your tongue or the inside of your cheek.

Your doctor will decide the correct dose and duration of therapy for you depending upon your age, body weight and severity of the infection.

Side Effects Of ONDAMAC MD TABLET

Common Side Effects of ONDAMAC MD TABLET:

• headache
• flushing (feeling of warmth)
• constipation
• Dizziness
• Diarrhea

Warning & Precautions

Pregnancy

Consult your doctor

Pregnant women should only use ONDAMAC MD TABLET if prescribed by a doctor, after assessing the benefits and risks.

Breastfeeding

Consult your doctor

Limited data is available on the use of ondansetron during breastfeeding. While no harmful effects have been reported in breastfed infants, ondansetron is excreted in breast milk. Therefore, breastfeeding mothers should consult a doctor before using this medicine as a precaution.

Driving and Using Machines

Use with Caution

Do not drive or operate any machines if you feel dizzy or uneasy after taking ONDAMAC MD TABLET.

Liver

Use with Caution

ONDAMAC MD TABLET should be used with caution in patients with liver problems. Consult your doctor before taking ONDAMAC MD TABLET.

Allergy

Contraindicated

Do not take ONDAMAC MD TABLET if you are allergic to ondansetron, granisetron or palonosetron or to any other ingredients of this medicine.

Heart Disease

Use with Caution

ONDAMAC MD TABLET should be used with caution in patients with heart diseases such as uneven heartbeats (arrhythmias) or congestive heart failure.

Use In Pediatrics

Monitoring required

ONDAMAC MD TABLET can be used in children if prescribed by the physician.

Use In Geriatrics

Monitoring required

ONDAMAC MD TABLET can be used in elderly patients if prescribed by the physician.

Interactions

A. Drug-Drug Interactions:

Before taking ONDAMAC MD TABLET, inform your doctor, if you are taking any of the following medicine:

• apomorphine (used to manage Parkinson’s disease)
• Antiepileptics (Ex. phenytoin, carbamazepine)
• Anti-TB agent (Ex. rifampicin)
• Pain killers (such as tramadol, methadone)
• Antipsychotic agents (Ex. haloperidol)
• Cardiac agents (Ex. amiodarone) and/or high blood pressure (Ex. atenolol, timolol)
• cancer medicines (Ex. doxorubicin, daunorubicin, monoclonal, trastuzumab) 
• Antibiotics (such as erythromycin, ketoconazole)
• Antidepressants, Sedatives, Anxiolytics (ex. fluoxetine, paroxetine, sertraline, fluvoxamine, citalopram, venlafaxine, duloxetine escitalopram)

Overdosage:

If you or anyone else accidentally takes too much of ONDAMAC MD TABLET, consult your doctor immediately or visit the nearby hospital.

Synopsis

FAQs About ONDAMAC MD TABLET

Q: Is ONDAMAC MD TABLET a chemo drug?

A: No, it is not a chemo drug. It belongs to a group of medicines called serotonin antagonists and used to manage side effects caused due to chemotherapy.

Q: What ONDAMAC MD TABLET is used for?

A: ONDAMAC MD TABLET is used to manage nausea and vomiting caused by medical managements like chemotherapy, radiotherapy or surgery.

Q: For how long should you take ONDAMAC MD TABLET?

A: Your doctor will advise you on how long you should continue to take ONDAMAC MD TABLET. Consult your doctor from time to time to review your management and assess your symptoms.

Q: What happens if you take more ONDAMAC MD TABLET than your required dose?

A: If you or anyone else accidentally takes too much of ONDAMAC MD TABLET, consult your doctor immediately or visit the nearby hospital.

Q: What side effects are seen with ONDAMAC MD TABLET?

A: The most common side effects of taking ONDAMAC MD TABLET are headaches, flushing (feeling of warmth), constipation. Consult your doctor if above side effects got worse.

References

1. KD. Tripathi. Section 11, Gastrointestinal Drugs. Essentials of medical pharmacology. Seventh edition. 2013. Page – 661.

2. LTS Lohmann Therapie-Systeme AG Lohmannstrasse. Andernach GERMANY [Revised April 2022] [Accessed on 29 September 2022] click here

3. Koland M, Sandeep V, Charyulu N. Fast Dissolving Sublingual Films of Ondansetron Hydrochloride: Effect of Additives on in vitro Drug Release and Mucosal Permeation. J Young Pharm. 2010 Jul;2(3):216-22. [Accessed on 29 September 2022] click here

4. Kumria R, Gupta V, Bansal S, Wadhwa J, Nair AB. Oral buccoadhesive films of ondansetron: Development and evaluation. Int J Pharm Investig. 2013 Apr;3(2):112-8. [Accessed on 29 September 2022] click here

5. Ondansetron Soluble Films. [Accessed on 29 September 2022] click here

6. Myoclinic. [Accessed on 29 September 2022] click here

Useful Diagnostic Tests

• Complete blood count

Author Details

Written By Srilekha. R - B.Pharm

Reviewed By Dr. Sankara Babu Gorle - MBBS, MD(Pharmacology) View profile

Last updated on 11 Feb 2025 | 04:40 PM(IST)