INTRODUCTION

OLMY D 40MG is a combination of Indapamide and Olmesartan which belongs to the group of medicines called Thiazide diuretics and Angiotensin-II receptor blockers respectively. It is used to manage hypertension. Hypertension (also known as high blood pressure) is a medical condition in which the force of the blood exerted against the walls of the artery remains very high, and as a result it may lead to severe damage to the blood vessels supplying several vital organs, like heart, kidney, or brain.

Olmesartan is an angiotensin II receptor blocker. It acts by relaxing the blood vessels supplying the vital organs. Indapamide is a thiazide-diuretic. It acts by increasing the removal of excess water and certain electrolytes (sodium and chloride) from the body in the form of urine. Collectively, they improve blood flow through the blood vessels and makes the heart to pump blood more smoothly with less pressure.

While undergoing therapy with OLMY D 40MG your doctor will regularly monitor your blood pressure, kidney function, blood sugar levels, blood cholesterol levels, blood uric acid levels and electrolyte profile (sodium, potassium, and magnesium levels) to avoid the risk of unwanted side effects.

Before taking OLMY D 40MG inform your doctor if you have diabetes, gout, or any muscle problems. You must also inform your doctor if you have any heart problems, low blood volume or are severely dehydrated due to excessive vomiting or diarrhea.

OLMY D 40MG is not recommended for use in patients with severe kidney or liver problems. It is also not suitable for use in patients with low blood potassium levels and in pregnant or breastfeeding women as it may cause serious harm to the growing baby.

OLMY D 40MG may make you feel dizzy while standing up suddenly or changing positions. Therefore, do not drive or operate any heavy tools or machines as a precaution. Also, avoid drinking alcohol as it might make you feel dizzier and drowsier.

The most common side effects of taking OLMY D 40MG are dizziness, nausea, headache, back pain, muscle cramps and tiredness. Consult your doctor if any of these side effect worsens.

USES OF OLMY D 40MG

• Manages hypertension (high blood pressure)

HOW OLMY D 40MG WORKS

OLMY D 40MG effectively controls blood pressure. It contains two medicines namely, olmesartan and indapamide. Olmesartan blocks the actions of certain hormones (angiotensin-II) in the body that causes narrowing of blood vessels and increase in blood pressure.

Indapamide increases the excretion of excess fluid and certain electrolytes (sodium and chloride) from the body in the form of urine. Together, they reduce blood volume, relax blood vessels, and improve blood flow through the blood vessels which helps the heart to pump blood more efficiently with less pressure.

DIRECTIONS FOR USE

Take OLMY D 40MG as directed by your physician. Swallow the medicine with a glass of water. Do not crush or chew the medicine. OLMY D 40MG can be taken with or without meals. Try to take OLMY D 40MG at the same time each day.

Your doctor will decide the correct dose and duration of therapy for you depending upon your age, body weight and health condition. Continue to take OLMY D 40MG for the stipulated duration instructed by your doctor without interruption to achieve better results.

SIDE EFFECTS OF OLMY D 40MG

HOW TO MANAGE SIDE EFFECTS

Nausea and Vomiting:

Take OLMY D 40MG with or just after a meal or a snack. Stick to simple meals. Avoid eating rich or spicy food. Consult your doctor if your nausea worsens.

Dizziness:

Try to rest and relax. Get enough sleep. Avoid driving or operating any tools or machines completely while you are feeling dizzy. Do not consume excessive alcohol, as it could aggravate your dizziness. Consult your doctor if your dizziness worsens.

Headache:

Rest and relax. Keep yourself hydrated by drinking plenty of fluids such as water or electrolytes. Applying a pain-relieving balm on your forehead can be beneficial. Do not consume excessive alcohol, as it could aggravate your headache. Consult your doctor if your headache worsens.

WARNING & PRECAUTIONS

INTERACTIONS

A. Drug-Drug Interaction:

Before taking OLMY D 40MG inform your doctor if you are taking any of the following:

• other medicines used to manage elevated blood pressure (such as aliskiren, captopril, enalapril, lisinopril, losartan, valsartan)
• lithium (a medicine used to manage depression)
• potassium supplements or potassium-sparing diuretics such as spironolactone, triamterene or amiloride (used to retain or increase potassium levels in the body)
• non-steroidal anti-inflammatory drugs (used for pain relief) such as indomethacin, celecoxib, ibuprofen, aspirin
• heparin (a medicine used to prevent blood clots)
• medicines used to manage abnormal heart rhythm (Ex. hydroquinidine, quinidine, amiodarone, sotalol, ibutilide, dofetilide or digitalis)
• bepridil (a medicine used to manage chest pain)
• stimulant laxatives (used to manage constipation) Ex. bisacodyl, sodium pico sulfate
• medicines used to manage mental disorders such as depression, psychosis, or anxiety (Ex. pimozide, amisulpride, haloperidol)
• medicines used to manage bacterial infections (Ex. sparfloxacin, moxifloxacin, erythromycin)
• vincamine injection (a medicine used to manage memory loss)
• pentamidine (a medicine used to manage pneumonia)
• halofantrine (a medicine used to manage malaria)
• mizolastine (a medicine used to manage allergic reactions)
• amphotericin B injection (a medicine used to manage fungal infections)
• baclofen (a medicine used to manage muscle spasm)
• allopurinol (a medicine used to manage gout)
• metformin (a medicine used to manage diabetes mellitus)
• oral corticosteroids (used to manage inflammation) Ex. dexamethasone, prednisolone, budesonide, salbutamol
• iodinated contrast media (used for X-rays)
• calcium supplements or calcium containing medicines
• tacrolimus, ciclosporin (used to prevent graft rejection)
• tetracosactide (a medicine used to manage Crohn’s disease)
• colesevelam (a medicine used to manage high blood cholesterol levels)
• cisapride (a medicine used to enhance bowel movements)
• diphemanil (a medicine used to manage stomach problems)
• methadone (a medicine used to manage addiction)

Overdosage:

If you or anyone else accidentally took more OLMY D 40MG, consult your doctor immediately or visit the nearby hospital straight away. Overdosage may cause side effects such as nausea, vomiting, dizziness, low blood pressure, cramps, changes in urine output, drowsiness, and confusion.

SYNOPSIS

MORE INFORMATION

• Keep OLMY D 40MG out of reach of children
• Store OLMY D 40MG at room temperature

FAQs ABOUT OLMY D 40MG

What are the uses of OLMY D 40MG?

OLMY D 40MG is used to manage hypertension. It contains two medicines namely olmesartan and indapamide. Olmesartan acts by relaxing the blood vessels and indapamide acts by increasing the excretion of sodium and water from the body in the form of urine. Collectively, they relax blood vessels, improves blood flow, and reduces blood pressure.

What type of a medicine is OLMY D 40MG?

OLMY D 40MG is an antihypertensive medicine used to reduce elevated blood pressure. It is a combination of two medicines namely olmesartan and indapamide. Olmesartan is an angiotensin II receptor blocker and indapamide is a thiazide-diuretic. They both acts together in reducing blood pressure.

Can the use of OLMY D 40MG cause kidney problems?

Yes. The use of OLMY D 40MG may affect your kidney functions. It is strictly not recommended for use in patients with severe kidney problems. It should be used with caution in patients with other kidney problems (such as dialysis or any recent kidney transplant). Therefore, consult your doctor before taking OLMY D 40MG as a precaution.

What happens when I stop taking OLMY D 40MG?

Do not stop taking OLMY D 40MG without consulting your doctor as your blood pressure may raise once again. Make sure to take OLMY D 40MG for the stipulated duration recommended by your doctor to achieve maximum results.

What is the best time to take OLMY D 40MG?

OLMY D 40MG can be taken with or without meals. Your doctor will decide the best time for you to take OLMY D 40MG based on your age, body weight and disease condition.

What to do if I forgot to take a dose of OLMY D 40MG?

If you have missed a dose of OLMY D 40MG, take it as soon as you remember. However, if it is time for the next dose of OLMY D 40MG, skip the missed dose and take the next one regularly. Do not take a double dose of OLMY D 40MG to compensate the missed ones.

What precautions should be followed while taking OLMY D 40MG?

Before taking OLMY D 40MG inform your doctor if you have diabetes, gout, or any muscle problems. You must also inform your doctor if you have any severe liver, kidney or heart problems, low blood volume or are severely dehydrated. Stop taking OLMY D 40MG and consult your doctor immediately if you become pregnant. Avoid driving or handling heavy tools or machines, as OLMY D 40MG may cause excessive dizziness or drowsiness. Regularly visit your doctor and take all the necessary blood test recommended by your doctor without fail.

Can OLMY D 40MG causes electrolyte imbalance?

Yes. OLMY D 40MG may the levels of certain electrolytes (sodium or potassium) in the body. To avoid this, your doctor will closely monitor the electrolytes levels in the blood periodically. However, if you experience any unusual symptoms such as chest pain, muscle weakness, irregular heartbeat, confusion, drowsiness, nausea, or vomiting, consult your doctor for advice.

Can I consume alcohol while taking OLMY D 40MG?

Avoid consumption of alcohol while taking OLMY D 40MG as it might make you feel dizzier and drowsier.

What happens if I accidentally take more OLMY D 40MG?

If you or anyone else accidentally took more OLMY D 40MG, consult your doctor immediately. Overdosage may cause side effects such as nausea, vomiting, dizziness, low blood pressure, cramps, changes in urine output, drowsiness, and confusion.

Can I take OLMY D 40MG daily?

Take OLMY D 40MG as advised by your physician. Your doctor will evaluate your health condition and suggests whether can you take OLMY D 40MG every day or not.

Is OLMY D 40MG safe to use in diabetic patients?

OLMY D 40MG may alter the blood sugar levels in your body. Therefore, it is necessary to inform your doctor if you have diabetes before taking OLMY D 40MG as a precaution. Your doctor will closely monitor you blood sugar levels to avoid the risk of side effects. Also, inform your doctor if you experience any unusual tiredness, hunger or thirst while undergoing therapy with OLMY D 40MG.

What are the side effects of OLMY D 40MG?

The most common side effects of taking OLMY D 40MG are dizziness, nausea, headache, back pain, muscle cramps and tiredness. Consult your doctor if any of these side effect worsens.

Can I stop taking OLMY D 40MG once my symptoms subside?

No. Do not stop taking OLMY D 40MG without consulting your doctor. As hypertension is a chronic condition, long term management may be necessary to control its symptoms. Therefore, take OLMY D 40MG as advised by your doctor for the stipulated duration. Premature discontinuation of therapy may increase your blood pressure once again.

Can the use of OLMY D 40MG affect the liver?

Yes. OLMY D 40MG may affect the way your liver work. It can elevate the levels of certain liver enzymes in your body. Therefore, it is strictly not recommended for use in patients with severe liver diseases. It should be used with caution in patients with other minor liver problems. Consult your doctor before taking it.

Can OLMY D 40MG be taken during pregnancy?

OLMY D 40MG is not recommended for use in pregnant women as it may cause serious harm to the growing foetus. Therefore, inform your doctor before taking OLMY D 40MG if you are pregnant, think you may be pregnant or planning to have a baby. If you become pregnant while undergoing therapy with OLMY D 40MG, stop taking it and consult your doctor immediately.

REFERENCES

1. KD. Tripathi. Diuretics & Drugs Affecting Renin Angiotensin System and Plasma Kinins. Essentials of medical pharmacology. Seventh edition. 2013. Page – 579 & 507.

2. Toshio Ogihara, Takao Saruta, Hiromi Rakugi, Ikuo Saito, Kazuaki Shimamoto, Hiroaki Matsuoka, Kazuyuki Shimada, Sadayoshi Ito, Masatsugu Horiuchi, Tsutomu Imaizumi, Shuichi Takishita, Jitsuo Higaki, Shigehiro Katayama, Genjiroh Kimura, Satoshi Umemura, Nobuyuki Ura, Koichi Hayashi, Masato Odawara, Norio Tanahashi, Toshihiko Ishimitsu, Naoki Kashihara, Satoshi Morita, and Satoshi Teramukai. Combinations of olmesartan and a calcium channel blocker or a diuretic in elderly hypertensive patients: a randomized, controlled trial. NCBI; PMC US National Library of Medicine, National Institute of Health. September 2014. [Accessed on 12th March 2022] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4166009//

3. Servier (Ireland) Industries Ltd. Electronic Medicines Compendium (EMC). [Revised in October 2021] [Accessed on 13th July 2022] https://www.medicines.org.uk/emc/files/pil.1152.pdf

4. Actavis Ltd. Health Products Regulatory Authority (HPRA). [Revised in July 2021] [Accessed on 9th April 2022] http://www.hpra.ie/img/uploaded/swedocuments/8c0fc811-cf88-4bd5-818e-609e07fe1190.pdf

USEFUL DIAGNOSTIC TESTS

• Kidney Function Test